Research Topics
Species | John G KeilpSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Neuropsychological function and suicidal behavior: attention control, memory and executive dysfunction in suicide attemptJ G Keilp
Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, NY, USA
Psychol Med 43:539-51. 2013..Executive dysfunction, distinct from other cognitive deficits in depression, has been associated with suicidal behavior. However, this dysfunction is not found consistently across samples...
Suicidal ideation and the subjective aspects of depressionJohn G Keilp
Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, NY 10032, United States
J Affect Disord 140:75-81. 2012....
Attention deficit in depressed suicide attemptersJohn G Keilp
Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, United States
Psychiatry Res 159:7-17. 2008....
Future suicide attempt and responses to serotonergic challengeJohn G Keilp
Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA
Neuropsychopharmacology 35:1063-72. 2010..Results suggest that blunted cortisol and unfavorable acute mood response to serotonergic challenge, in the context of the general activating effects of these drugs, may be a risk factor for later suicide attempt...
WAIS-III and WMS-III performance in chronic Lyme diseaseJohn G Keilp
Columbia University College of Physicians and Surgeons, Department of Psychiatry, New York, New York 10032, USA
J Int Neuropsychol Soc 12:119-29. 2006..Deficits in chronic Lyme disease are consistent with a subtle neuropathological process affecting multiple performance tasks, although further work is needed to definitively rule out nonspecific illness effects...
Early visual information processing deficit in depression with and without Borderline Personality DisorderJohn G Keilp
Department of Neuroscience, Columbia University Medical College and New York State Psychiatric Institute, Box 42, 1051 Riverside Drive, New York, NY 10032, USA
Psychiatry Res 149:139-45. 2007..Poor early information processing appears to be a feature of Borderline Personality Disorder, and may play a role in the impulsive behavior that is characteristic of the disorder...
Neuropsychological characteristics as predictors of SSRI treatment response in depressed subjectsMarianne Gorlyn
Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA
J Neural Transm 115:1213-9. 2008..Cognitive slowing may mediate the working memory and executive function deficits found in nonresponders. These findings can inform exploration for pharmacogenetic endophenotypes...
Change in cognitive functioning in depressed older adults following treatment with sertraline or nortriptylineMichelle E Culang-Reinlieb
Graduate Center, City University of New York, New York, NY, USA
Int J Geriatr Psychiatry 27:777-84. 2012..The aim of this study was to compare the impact of nortriptyline to sertraline on change in cognitive functioning in depressed older adults...
Aggressiveness, not impulsiveness or hostility, distinguishes suicide attempters with major depressionJohn G Keilp
Department of Neuroscience, New York State Psychiatric Institute, New York, USA
Psychol Med 36:1779-88. 2006....
The specificity of neuropsychological impairment in predicting antidepressant non-response in the very old depressedJoel R Sneed
Department of Psychiatry, Columbia State University, New York State Psychiatric Institute, New York, NY 10032, USA
Int J Geriatr Psychiatry 23:319-23. 2008..2007). The purpose of this study was to ascertain whether this effect is specific to response inhibition or whether impairment in other cognitive domains also predicts non-response...
The WAIS-III and major depression: absence of VIQ/PIQ differencesMarianne Gorlyn
Department of Neuroscience, New York State Psychiatric Institute, NY 10032, USA
J Clin Exp Neuropsychol 28:1145-57. 2006..Results suggest general intellectual performance in depression is best characterized by deficits in processing speed, rather than global nonverbal abilities, and that this deficit is consistent across depression subtypes...
Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathyBrian A Fallon
Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
Arch Gen Psychiatry 66:554-63. 2009..There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease...
DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory abilityHaiyan Xu
Department of Genetics and Development, Columbia University, New York, NY 10032, USA
Schizophr Res 90:104-7. 2007..We propose that an interaction of the DRD2 C957T and COMT Val158Met may be involved in the generation of some working memory deficits in schizophrenia...
The impact of borderline personality disorder and anxiety on neuropsychological performance in major depressionEric A Fertuck
Department of Neuroscience, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
J Pers Disord 20:55-70. 2006....
Response of cortical metabolic deficits to serotonergic challenge in familial mood disordersLawrence S Kegeles
Department of Psychiatry, Columbia University, New York, NY, USA
Am J Psychiatry 160:76-82. 2003..The authors applied a dl-fenfluramine challenge method to study metabolic response in this region to serotonergic challenge in familial major depression...
Correlates of trait impulsiveness in performance measures and neuropsychological testsJohn G Keilp
Department of Neuroscience, New York State Psychiatric Institute, Columbia University Medical College, Box 42, 1051 Riverside Drive, New York, NY 10032, USA
Psychiatry Res 135:191-201. 2005....
Are BPI and BPII suicide attempters distinct neuropsychologically?Jill M Harkavy-Friedman
New York State Psychiatric Institute and Columbia University, USA
J Affect Disord 94:255-9. 2006..Neuropsychological functioning is a means of understanding similarities and differences between diagnostic groups...
Altered subicular MAP2 immunoreactivity in schizophreniaGorazd Rosoklija
Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
Prilozi 26:13-34. 2005..The chemical or structural abnormalities underlying decreased MAP2 immunoreactivity in schizophrenia remain to be determined...
Response inhibition predicts poor antidepressant treatment response in very old depressed patientsJoel R Sneed
Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY 10032, USA
Am J Geriatr Psychiatry 15:553-63. 2007..There have been mixed findings regarding the prognostic significance of age of onset, executive dysfunction, and hyperintensity burden on treatment outcome in late-life depression...
Neural responses to incongruency in a blocked-trial Stroop fMRI task in major depressive disorderToshiaki Kikuchi
Department of Psychiatry, Columbia University, New York, NY 10032, USA
J Affect Disord 143:241-7. 2012..The neural correlates of this deficit are not well described. To examine how this deficit relates to pathophysiological abnormalities in MDD, we conducted an fMRI Stroop study comparing MDD subjects to controls...
Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operationsGerard E Bruder
Department of Psychiatry, Columbia University, New York, USA
Biol Psychiatry 58:901-7. 2005..This report examines the relation of COMT genotypes to performance on a battery of working memory tests differing in the cognitive operations to be performed on the material...
