John G Keilp

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Cerebral blood flow patterns underlying the differential impairment in category vs letter fluency in Alzheimer's disease
    J G Keilp
    Department of Brain Imaging, New York State Psychiatric Institute, New York, USA
    Neuropsychologia 37:1251-61. 1999
  2. pmc Early visual information processing deficit in depression with and without Borderline Personality Disorder
    John G Keilp
    Department of Neuroscience, Columbia University Medical College and New York State Psychiatric Institute, Box 42, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 149:139-45. 2007
  3. ncbi request reprint Aggressiveness, not impulsiveness or hostility, distinguishes suicide attempters with major depression
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, New York, USA
    Psychol Med 36:1779-88. 2006
  4. ncbi request reprint Correlates of trait impulsiveness in performance measures and neuropsychological tests
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, Columbia University Medical College, Box 42, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 135:191-201. 2005
  5. pmc Change in cognitive functioning in depressed older adults following treatment with sertraline or nortriptyline
    Michelle E Culang-Reinlieb
    Graduate Center, City University of New York, New York, NY, USA
    Int J Geriatr Psychiatry 27:777-84. 2012
  6. pmc Attention deficit in depressed suicide attempters
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, United States
    Psychiatry Res 159:7-17. 2008
  7. pmc Neuropsychological characteristics as predictors of SSRI treatment response in depressed subjects
    Marianne Gorlyn
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA
    J Neural Transm 115:1213-9. 2008
  8. ncbi request reprint The specificity of neuropsychological impairment in predicting antidepressant non-response in the very old depressed
    Joel R Sneed
    Department of Psychiatry, Columbia State University, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Geriatr Psychiatry 23:319-23. 2008
  9. pmc Future suicide attempt and responses to serotonergic challenge
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA
    Neuropsychopharmacology 35:1063-72. 2010
  10. ncbi request reprint The WAIS-III and major depression: absence of VIQ/PIQ differences
    Marianne Gorlyn
    Department of Neuroscience, New York State Psychiatric Institute, NY 10032, USA
    J Clin Exp Neuropsychol 28:1145-57. 2006

Detail Information

Publications25

  1. ncbi request reprint Cerebral blood flow patterns underlying the differential impairment in category vs letter fluency in Alzheimer's disease
    J G Keilp
    Department of Brain Imaging, New York State Psychiatric Institute, New York, USA
    Neuropsychologia 37:1251-61. 1999
    ..Letter Fluency deficits, on the other hand, carry significant information about the degree to which perfusion deficits have spread to frontal cortex...
  2. pmc Early visual information processing deficit in depression with and without Borderline Personality Disorder
    John G Keilp
    Department of Neuroscience, Columbia University Medical College and New York State Psychiatric Institute, Box 42, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 149:139-45. 2007
    ..Poor early information processing appears to be a feature of Borderline Personality Disorder, and may play a role in the impulsive behavior that is characteristic of the disorder...
  3. ncbi request reprint Aggressiveness, not impulsiveness or hostility, distinguishes suicide attempters with major depression
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, New York, USA
    Psychol Med 36:1779-88. 2006
    ....
  4. ncbi request reprint Correlates of trait impulsiveness in performance measures and neuropsychological tests
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, Columbia University Medical College, Box 42, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 135:191-201. 2005
    ....
  5. pmc Change in cognitive functioning in depressed older adults following treatment with sertraline or nortriptyline
    Michelle E Culang-Reinlieb
    Graduate Center, City University of New York, New York, NY, USA
    Int J Geriatr Psychiatry 27:777-84. 2012
    ..The aim of this study was to compare the impact of nortriptyline to sertraline on change in cognitive functioning in depressed older adults...
  6. pmc Attention deficit in depressed suicide attempters
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, United States
    Psychiatry Res 159:7-17. 2008
    ....
  7. pmc Neuropsychological characteristics as predictors of SSRI treatment response in depressed subjects
    Marianne Gorlyn
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA
    J Neural Transm 115:1213-9. 2008
    ..Cognitive slowing may mediate the working memory and executive function deficits found in nonresponders. These findings can inform exploration for pharmacogenetic endophenotypes...
  8. ncbi request reprint The specificity of neuropsychological impairment in predicting antidepressant non-response in the very old depressed
    Joel R Sneed
    Department of Psychiatry, Columbia State University, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Geriatr Psychiatry 23:319-23. 2008
    ..2007). The purpose of this study was to ascertain whether this effect is specific to response inhibition or whether impairment in other cognitive domains also predicts non-response...
  9. pmc Future suicide attempt and responses to serotonergic challenge
    John G Keilp
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY, USA
    Neuropsychopharmacology 35:1063-72. 2010
    ..Results suggest that blunted cortisol and unfavorable acute mood response to serotonergic challenge, in the context of the general activating effects of these drugs, may be a risk factor for later suicide attempt...
  10. ncbi request reprint The WAIS-III and major depression: absence of VIQ/PIQ differences
    Marianne Gorlyn
    Department of Neuroscience, New York State Psychiatric Institute, NY 10032, USA
    J Clin Exp Neuropsychol 28:1145-57. 2006
    ..Results suggest general intellectual performance in depression is best characterized by deficits in processing speed, rather than global nonverbal abilities, and that this deficit is consistent across depression subtypes...
  11. doi request reprint Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathy
    Brian A Fallon
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Arch Gen Psychiatry 66:554-63. 2009
    ..There is controversy regarding whether objective neurobiological abnormalities exist after intensive antibiotic treatment for Lyme disease...
  12. ncbi request reprint The impact of borderline personality disorder and anxiety on neuropsychological performance in major depression
    Eric A Fertuck
    Department of Neuroscience, Columbia University New York State Psychiatric Institute, New York, NY 10032, USA
    J Pers Disord 20:55-70. 2006
    ....
  13. doi request reprint Iowa gambling task performance in currently depressed suicide attempters
    Marianne Gorlyn
    Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, NY 10032, USA
    Psychiatry Res 207:150-7. 2013
    ..Psychometric and conceptual issues surrounding the IGT also appear to affect its utility as a general marker of suicidal behavior risk...
  14. doi request reprint SSRI versus bupropion effects on symptom clusters in suicidal depression: post hoc analysis of a randomized clinical trial
    Michael F Grunebaum
    Molecular Imaging and Neuropathology Division, New York State Psychiatric Institute, 1051 Riverside Drive, Box 42, New York, NY 10032
    J Clin Psychiatry 74:872-9. 2013
    ..Identifying the depression symptoms most closely associated with suicidal thoughts and which medications provide the fastest depression relief may help suicide prevention...
  15. ncbi request reprint DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability
    Haiyan Xu
    Department of Genetics and Development, Columbia University, New York, NY 10032, USA
    Schizophr Res 90:104-7. 2007
    ..We propose that an interaction of the DRD2 C957T and COMT Val158Met may be involved in the generation of some working memory deficits in schizophrenia...
  16. pmc Neural responses to incongruency in a blocked-trial Stroop fMRI task in major depressive disorder
    Toshiaki Kikuchi
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    J Affect Disord 143:241-7. 2012
    ..The neural correlates of this deficit are not well described. To examine how this deficit relates to pathophysiological abnormalities in MDD, we conducted an fMRI Stroop study comparing MDD subjects to controls...
  17. pmc Suicidal ideation and the subjective aspects of depression
    John G Keilp
    Department of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, NY 10032, United States
    J Affect Disord 140:75-81. 2012
    ....
  18. ncbi request reprint Are BPI and BPII suicide attempters distinct neuropsychologically?
    Jill M Harkavy-Friedman
    New York State Psychiatric Institute and Columbia University, USA
    J Affect Disord 94:255-9. 2006
    ..Neuropsychological functioning is a means of understanding similarities and differences between diagnostic groups...
  19. ncbi request reprint Altered subicular MAP2 immunoreactivity in schizophrenia
    Gorazd Rosoklija
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    Prilozi 26:13-34. 2005
    ..The chemical or structural abnormalities underlying decreased MAP2 immunoreactivity in schizophrenia remain to be determined...
  20. pmc Polyunsaturated fatty acid associations with dopaminergic indices in major depressive disorder
    M Elizabeth Sublette
    Department of Psychiatry, Columbia University, New York, NY, USA
    Int J Neuropsychopharmacol 17:383-91. 2014
    ..The robust relationship of omega-3 PUFAs with dopaminergic but not serotonergic indices suggests that omega-6:omega-3 balance may impact depression pathophysiology through effects on the dopaminergic system...
  21. ncbi request reprint Response inhibition predicts poor antidepressant treatment response in very old depressed patients
    Joel R Sneed
    Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Geriatr Psychiatry 15:553-63. 2007
    ..There have been mixed findings regarding the prognostic significance of age of onset, executive dysfunction, and hyperintensity burden on treatment outcome in late-life depression...
  22. ncbi request reprint Response of cortical metabolic deficits to serotonergic challenge in familial mood disorders
    Lawrence S Kegeles
    Department of Psychiatry, Columbia University, New York, NY, USA
    Am J Psychiatry 160:76-82. 2003
    ..The authors applied a dl-fenfluramine challenge method to study metabolic response in this region to serotonergic challenge in familial major depression...
  23. ncbi request reprint Neurocognitive predictors of antidepressant clinical response
    Gerard E Bruder
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA Division of Cognitive Neuroscience, New York State Psychiatric Institute, New York, NY, USA Electronic address
    J Affect Disord 166:108-14. 2014
    ..Executive dysfunction and psychomotor slowing in depressed patients have been associated with poor antidepressant clinical response, but little is known about the value of neurocognitive tests for differential prediction of response...
  24. ncbi request reprint WAIS-III and WMS-III performance in chronic Lyme disease
    John G Keilp
    Columbia University College of Physicians and Surgeons, Department of Psychiatry, New York, New York 10032, USA
    J Int Neuropsychol Soc 12:119-29. 2006
    ..Deficits in chronic Lyme disease are consistent with a subtle neuropathological process affecting multiple performance tasks, although further work is needed to definitively rule out nonspecific illness effects...
  25. ncbi request reprint Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations
    Gerard E Bruder
    Department of Psychiatry, Columbia University, New York, USA
    Biol Psychiatry 58:901-7. 2005
    ..This report examines the relation of COMT genotypes to performance on a battery of working memory tests differing in the cognitive operations to be performed on the material...

Research Grants4

  1. Neuropsychological Dysfunction in Suicidal Behavior
    John Keilp; Fiscal Year: 2002
    ..Data from this study will provide much-needed information about a neglected realm of functioning in those at risk for suicide and identify the impairments in thinking that might be used to predict suicidal behavior. ..
  2. Neuropsychological Dysfunction in Suicidal Behavior
    John Keilp; Fiscal Year: 2003
    ..Data from this study will provide much-needed information about a neglected realm of functioning in those at risk for suicide and identify the impairments in thinking that might be used to predict suicidal behavior. ..
  3. Neuropsychological Dysfunction in Suicidal Behavior
    John Keilp; Fiscal Year: 2004
    ..Data from this study will provide much-needed information about a neglected realm of functioning in those at risk for suicide and identify the impairments in thinking that might be used to predict suicidal behavior. ..
  4. Neuropsychological Dysfunction in Suicidal Behavior
    John Keilp; Fiscal Year: 2005
    ..Data from this study will provide much-needed information about a neglected realm of functioning in those at risk for suicide and identify the impairments in thinking that might be used to predict suicidal behavior. ..