Research Topics
Species | Sanja JelicSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Sleep-disordered breathing in acute decompensated heart failureSanja Jelic
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Curr Heart Fail Rep 6:169-75. 2009..The presence of CSA is associated with increased mortality in HF patients. Efficacious suppression of central sleep apnea with continuous positive airway pressure therapy may reduce mortality in HF...
Inflammation, oxidative stress, and the vascular endothelium in obstructive sleep apneaSanja Jelic
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Trends Cardiovasc Med 18:253-60. 2008....
Diagnostic and therapeutic approach to coexistent chronic obstructive pulmonary disease and obstructive sleep apneaSanja Jelic
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Int J Chron Obstruct Pulmon Dis 3:269-75. 2008..The aim of the present review is to discuss the diagnostic approach to patients with both conditions and to delineate the benefits of timely recognition and treatment of OSA in patients with COPD...
Clinical review: airway hygiene in the intensive care unitSanja Jelic
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA
Crit Care 12:209. 2008..Available data are distilled into recommendations for the maintenance of airway hygiene in ICU patients...
Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apneaSanja Jelic
Columbia University College of Physicians and Surgeons, Division of Pulmonary, Allergy, and Critical Care Medicine, PH8 Center, Room 840, 630 W 168th St, New York, NY 10032, USA
Circulation 117:2270-8. 2008..The effects of continuous positive airway pressure (CPAP) therapy on endothelial function and repair capacity were assessed...
Diagnostic usefulness of B-type natriuretic peptide and functional consequences of muscle alterations in COPD and chronic heart failureSanja Jelic
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, PH 8, Room 840, 630 West 168th St, New York, NY 10032, USA
Chest 130:1220-30. 2006..Exercise training reverses skeletal muscle abnormalities in patients with COPD or chronic heart failure and may be particularly indicated in patients with coexistent COPD and chronic heart failure...
Endothelial repair capacity and apoptosis are inversely related in obstructive sleep apneaSanja Jelic
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Vasc Health Risk Manag 5:909-20. 2009..To investigate the impact of obstructive sleep apnea (OSA) on endothelial repair capacity and apoptosis in the absence of potentially confounding factors including obesity...
Vascular inflammation in obesity and sleep apneaSanja Jelic
Columbia University College of Physicians and Surgeons, Division of Pulmonary, Allergy, and Critical Care Medicine, PH8 Center, Room 101, 630 W 168th St, New York, NY 10032, USA
Circulation 121:1014-21. 2010..We investigated directly whether the endothelial alterations that are attributed commonly to obesity are in fact related to OSA...
Endothelial function in obstructive sleep apneaAmy Atkeson
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Prog Cardiovasc Dis 51:351-62. 2009..Treatment of OSA improves endothelial vasomotor tone and reduces inflammation. We review the evidence and possible mechanisms of endothelial dysfunction as well as the effect of treatment on endothelial function in OSA...
Mechanisms of endothelial dysfunction in obstructive sleep apneaAmy Atkeson
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA
Vasc Health Risk Manag 4:1327-35. 2008..The present review focuses on possible mechanisms that underlie endothelial activation and inflammation in OSA...
The effect of ventilation on spectral analysis of heart rate and blood pressure variability during exerciseMatthew N Bartels
Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, Box 38, New York, NY 10032, USA
Respir Physiol Neurobiol 144:91-8. 2004..These findings suggest that the increases in ventilation associated with incremental exercise do not significantly affect spectral analysis of cardiovascular autonomic modulation in healthy subjects...
Increased sympathetic and decreased parasympathetic cardiovascular modulation in normal humans with acute sleep deprivationXu Zhong
Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, 622 West 168th Street, VC 12-206, New York, NY 10032, USA
J Appl Physiol 98:2024-32. 2005..In summary, acute SD was associated with increased sympathetic and decreased parasympathetic cardiovascular modulation and decreased BRS, most consistently in the seated position and during simple reaction-time testing...
Vascular endothelial sampling and analysis of gene transcripts: a new quantitative approach to monitor vascular inflammationDuygu Onat
Department of Medicine, Columbia Univ, New York, NY, USA
J Appl Physiol 103:1873-8. 2007..We introduce venous endothelial sampling coupled to quantitative analysis of gene transcripts by real-time PCR, as a novel approach to study endothelial gene expression in human subjects...
Reproducibility of heart rate and blood pressure variability in patients with chronic obstructive pulmonary diseaseMatthew N Bartels
Dept of Rehabilitation Medicine, College of Physicians and Surgeons of Columbia University, 630 West 168th St, 38, New York, NY 10034, USA
Clin Auton Res 14:194-6. 2004..Reproducibility of these measurements may allow for a non-invasive evaluation of autonomic tone in response to treatments in COPD patients...
Supplemental oxygen increases arterial stiffness in chronic obstructive pulmonary diseaseMatthew N Bartels
Department of Rehabilitation Medicine, Columbia University, 630 West 168th Street, Box 38, New York, NY 10032, USA
Respir Med 98:84-9. 2004..In order to investigate whether peripheral arterial stiffness changes may play a role, we evaluated changes in peripheral arterial stiffness and BRS after SuppO2...
High-frequency modulation of heart rate variability during exercise in patients with COPDMatthew N Bartels
Human Performance Laboratory, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, NY 10032, USA
Chest 124:863-9. 2003..CONCLUSION: These data suggest that, in contrast to control subjects, the balance of sympathetic to parasympathetic cardiac modulation decreases in patients with COPD during maximal volitional exercise...
Predictors of oxidative stress in heart failure patients with Cheyne-Stokes respirationAna C Krieger
Weill Cornell Medical College of Cornell University, New York, NY 10065, USA
Sleep Breath 15:827-35. 2011..We hypothesized that the presence of Cheyne-Stokes respiration is associated with oxidative stress by increasing the formation of reactive oxygen species in patients with heart failure...
Chronic obstructive pulmonary disease in the elderly: an update on pharmacological managementAmy L Dzierba
Department of Pharmacy, New York Presbyterian Hospital, Columbia University, New York, New York, USA
Drugs Aging 26:447-56. 2009..The present review focuses on the special considerations regarding initiation and maintenance of pharmacotherapy in elderly patients with stable COPD...
Coexistent chronic obstructive pulmonary disease and heart failure in the elderlyMargherita Padeletti
Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, United States
Int J Cardiol 125:209-15. 2008..Long-term beta adrenergic blockade has been repeatedly shown to improve survival in elderly patients with CHF due to LV systolic dysfunction and, contrary to conventional belief, is well tolerated by patients with COPD...
Therapeutic update: non-selective beta- and alpha-adrenergic blockade in patients with coexistent chronic obstructive pulmonary disease and chronic heart failureTseday E Sirak
Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA
J Am Coll Cardiol 44:497-502. 2004..Alpha-adrenergic blockade may promote mild bronchodilation that offsets non-selective beta blockade-induced bronchoconstriction in patients with obstructive airway disease...
Arterial stiffness increases during obstructive sleep apneasSanja Jelic
Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Sleep 25:850-5. 2002..These data suggest that arterial stiffness may be a sensitive measure of acute arterial vasomotor perturbation in this setting and may have implications concerning cardiovascular sequelae in patients with OSA...
Extracorporeal membrane oxygenation in pregnancyJennifer A Cunningham
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Obstet Gynecol 108:792-5. 2006..CONCLUSION: Extracorporeal membrane oxygenation can be life saving when initiated early in pregnant patients with severe acute respiratory insufficiency unresponsive to conventional mechanical ventilation...
Sleep disordered breathing and arrhythmia burden in pacemaker recipientsMargherita Padeletti
Department of Cardiovascular Diseases, University of Siena, Siena, Italy
Pacing Clin Electrophysiol 33:1462-6. 2010..We investigated whether a novel PM that utilizes variations in transthoracic impedance to record the fluctuations in breathing pattern and minute ventilation could be used to screen patients for SDB...
Seek and treat obstructive sleep apnea in heart failureThierry H Le Jemtel
J Am Coll Cardiol 49:1632-3. 2007
Diagnostic and therapeutic challenges in patients with coexistent chronic obstructive pulmonary disease and chronic heart failureThierry H Le Jemtel
Division of Cardiology, Tulane University, New Orleans, Louisiana 70112 2699, USA
J Am Coll Cardiol 49:171-80. 2007..A large body of data indicates that patients with COPD tolerate well selective beta-blockade that should not be denied to CHF patients with concomitant COPD...
The risk profile for obstructive sleep apnea does not affect the recurrence of atrial fibrillationLuigi Padeletti
Internal Medicine and Cardiology, University of Firenze, Firenze, Italy
Pacing Clin Electrophysiol 29:727-32. 2006..We hypothesized that OSA may aggravate AF in patients with pacemakers implanted for sinus bradycardia who had documented paroxysmal AF...
