Affiliation: Columbia University
Abate F, Zairis S, Ficarra E, Acquaviva A, Wiggins C, Frattini V, et al
. Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer. BMC Syst Biol. 2014;8:97 pubmed publisher
..We show the effectiveness of Pegasus in predicting new driver fusions in 176 RNA-Seq samples of glioblastoma multiforme (GBM) and 23 cases of anaplastic large cell lymphoma (ALCL). ..
Iavarone A, Lasorella A. Id proteins in neural cancer. Cancer Lett. 2004;204:189-96 pubmed
..Future work will be required to fully elucidate the molecular networks engaged by Id proteins to contribute to the essential hallmarks of neural cancer...
Iavarone A, King E, Dai X, Leone G, Stanley E, Lasorella A. Retinoblastoma promotes definitive erythropoiesis by repressing Id2 in fetal liver macrophages. Nature. 2004;432:1040-5 pubmed
..1, a master regulator of macrophage differentiation. Thus, Rb has a cell autonomous function in fetal liver macrophages, and restrains Id2 in these cells in order to implement definitive erythropoiesis. ..
Anjum S, Morganella S, D Angelo F, Iavarone A, Ceccarelli M. VEGAWES: variational segmentation on whole exome sequencing for copy number detection. BMC Bioinformatics. 2015;16:315 pubmed publisher
..In terms of both accuracy and time, VEGAWES provided better results on the synthetic data and tumor samples demonstrating its potential in robust detection of aberrant regions in the genome. ..
Ceccarelli M, Barthel F, Malta T, Sabedot T, Salama S, Murray B, et al
. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 2016;164:550-63 pubmed publisher
..Understanding of cohesive disease groups may aid improved clinical outcomes. ..