Research Topics
Species | Daphne T HsuSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Outcome after the single-stage, nonfenestrated Fontan procedureD T Hsu
Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Circulation 96:II-335-40. 1997..Other centers perform single-stage Fontan operations and do not fenestrate. Thus controversies have arisen regarding the indications for the staged procedure versus single stage and for fenestration versus no fenestration...- Biological and psychological differences in the child and adolescent transplant recipientDaphne T Hsu
Columbia University Medical Center, Morgan Stanley Children s Hospital of New York Presbyterian, NY 10032, USA
Pediatr Transplant 9:416-21. 2005..Further studies to elucidate the importance of both age-related pharmacokinetic and behavioral factors are needed to formulate therapeutic interventions that would improve adherence and patient outcomes... 
Lessons learned from the pediatric heart transplant studyDaphne T Hsu
Department of Pediatrics, Columbia University, New York, NY, USA
Congenit Heart Dis 1:54-62. 2006....- BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol TrialScott R Auerbach
Division of Pediatric Cardiology, Columbia University, Morgan Stanley Children s Hospital of New York Presbyterian, New York, NY, USA
Circ Heart Fail 3:606-11. 2010..This study was designed to determine whether BNP levels predict outcomes in patients with moderate symptomatic HF... - Trends and outcomes in transplantation for complex congenital heart disease: 1984 to 2004Jonathan M Chen
Division of Pediatric Cardiac Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
Ann Thorac Surg 78:1352-61; discussion 1352-61. 2004..We undertook the current single center study to evaluate surgical outcomes and lessons learned through a nearly twenty year experience with cardiac transplantation for complex congenital heart disease... - Outcomes in pediatric cardiac transplantation with a positive HLA cross-matchMarc E Richmond
Division of Pediatric Cardiology, Department of Pediatrics, Morgan Stanley Children s Hospital of New York Presbyterian, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Pediatr Transplant 16:29-35. 2012..Further investigation is warranted to define which patients with a positive cross-match will do poorly... - Ventricular diastolic stiffness predicts perioperative morbidity and duration of pleural effusions after the Fontan operationCara A Garofalo
Department of Pediatrics, Columbia College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Circulation 114:I56-61. 2006..These observations could improve risk stratification and clinical management of children at high-risk undergoing the Fontan operation... - Cardiac retransplantation in high risk pediatric patientsMarc E Richmond
Division of Pediatric Cardiology, Morgan Stanley Children s Hospital of New York Presbyterian, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Pediatr Transplant 11:615-23. 2007..Overall, patients had excellent survival after retransplantation even in those with risk factors for poor outcome... - Tissue Doppler-derived diastolic myocardial velocities are abnormal in pediatric cardiac transplant recipients in the absence of endomyocardial rejectionSebastian Strigl
Division of Pediatric Cardiology, Columbia College of Physicians and Surgeons, New York, NY, 10032, USA
Pediatr Cardiol 29:749-54. 2008..Abnormalities in tissue Doppler-derived diastolic myocardial velocities are common in pediatric cardiac transplant recipients free of acute rejection... - Pediatric heart transplantation across ABO blood type barriers: a case studyRose J Rodriguez
Children's Hospital of New York-Presbyterian, New York, NY, USA
Prog Transplant 15:161-5. 2005..This article presents a case study of a neonate with congenital heart disease who underwent one of the first successful ABO-incompatible heart transplantations in the United States... 
Birth weight and prematurity in infants with single ventricle physiology: pediatric heart network infant single ventricle trial screened populationRichard V Williams
Department of Pediatrics, University of Utah, Salt Lake City, Utah, USA
Congenit Heart Dis 5:96-103. 2010....- Utility of post-transplant anti-HLA antibody measurements in pediatric cardiac transplant recipientsSteve Xydas
Division of Cardiothoracic Surgery, Department of Surgery, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Heart Lung Transplant 24:1289-96. 2005.... - Heart transplantation to a physiologic single lung in patients with congenital heart diseaseJacqueline M Lamour
Division of Pediatric Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Heart Lung Transplant 23:948-53. 2004.... - Cardiac transplantation after the Fontan or Glenn procedureK Anitha Jayakumar
Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, New York, USA
J Am Coll Cardiol 44:2065-72. 2004.... - The Fontan patient: inconsistencies in medication therapy across seven pediatric heart network centersPage A W Anderson
Department of Pediatrics, Duke University Medical Center, Durham, NC, USA
Pediatr Cardiol 31:1219-28. 2010..Medication use rates varied widely among the centers, even with controls for center differences in patient characteristics. Prospective therapeutic trials are needed to guide the medical treatment of Fontan patients... - Ross procedure in infants and toddlers followed into childhoodIsmee A Williams
Division of Pediatric Cardiology, Morgan Stanley Children s Hospital of New York, New York, NY 10032, USA
Circulation 112:I390-5. 2005..The Ross procedure is commonly used to treat aortic valve disease in pediatric and adult patients. For infants, data are limited regarding survival, reintervention, autograft growth, and function... - Effects of growth hormone therapy in children after cardiac transplantationSeema Mital
Division of Pediatric Cardiology, Department of Pediatrics, Columbia University, New York, New York, USA
J Heart Lung Transplant 25:772-7. 2006..The safety and efficacy of GH after pediatric cardiac transplantation is not known. The objective of this study was to evaluate growth and cardiovascular effects of GH in children with growth failure after cardiac transplantation... - Functional state following the Fontan procedureIsmee A Williams
Department of Pediatrics, Division of Cardiology, Columbia University Medical Centre, New York, New York, USA
Cardiol Young 19:320-30. 2009..Despite improvements in outcomes after completion of the Fontan circulation, long-term functional state varies. We sought to identify pre- and postoperative characteristics associated with overall function... - Association of impaired linear growth and worse neurodevelopmental outcome in infants with single ventricle physiology: a report from the pediatric heart network infant single ventricle trialChitra Ravishankar
Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA Electronic address
J Pediatr 162:250-256.e2. 2013..To describe neurodevelopmental outcomes in infants with single ventricle (SV) physiology and determine factors associated with worse outcomes... - Coronary artery dilation in sickle cell diseaseGeorge T Nicholson
Department of Pediatrics, Children s Hospital at Montefiore, Bronx, NY, USA
J Pediatr 159:789-794.e1-2. 2011..To evaluate the prevalence of coronary artery dilation in children with sickle cell disease (SCD)... - Management of aortopulmonary collaterals in children following cardiac transplantation for complex congenital heart diseaseUsha S Krishnan
Department of Pediatrics Pediatric Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York 10595, USA
J Heart Lung Transplant 23:564-9. 2004..High output cardiac failure due to residual aortopulmonary collaterals can affect outcome following heart transplantation... - Rationale and design of a trial of angiotensin-converting enzyme inhibition in infants with single ventricleDaphne T Hsu
Columbia University, New York, NY, USA
Am Heart J 157:37-45. 2009..Infants with single-ventricle physiology show abnormalities in ventricular function as well as poor growth. The ability of an ACE inhibitor to preserve ventricular function and improve growth in these infants is unknown... - Outcome of idiopathic restrictive cardiomyopathy in childrenRachel J Weller
Division of Pediatric Cardiology, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Am J Cardiol 90:501-6. 2002..No risk factors for the development of pulmonary hypertension were identified; therefore, all children with IRC should undergo serial monitoring of their PVRI, and any increase should prompt a transplant evaluation... - Dilated cardiomyopathy and heart failure in childrenDaphne T Hsu
Department of Pediatrics, Albert Einstein College of Medicine, 3415 Bainbrige Avenue, Bronx, NY 10467, USA
Heart Fail Clin 6:415-32, vii. 2010..The predictors for better and worse outcomes are reviewed. Guidelines for the use of medical and surgical therapies to treat heart failure in children are summarized... - Spontaneous regression of left ventricular dilation in children with restrictive ventricular septal defectsCharles S Kleinman
Department of Pediatrics, Division of Pediatric Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Pediatr 150:583-6. 2007.... - Children undergoing heart transplant are at increased risk for postoperative vasodilatory shockJames S Killinger
Department of Pediatrics, Division of Critical Care Medicine, Columbia University, College of Physicians and Surgeons, Bronx, NY, USA
Pediatr Crit Care Med 10:335-40. 2009..To determine the incidence of vasodilatory shock (VDS) in children after cardiopulmonary bypass (CPB), and to describe this syndrome of post-CPB VDS in children... - Carvedilol for children and adolescents with heart failure: a randomized controlled trialRobert E Shaddy
Department of Pediatrics, University of Utah School of Medicine and Primary Children s Medical Center, Salt Lake City, USA
JAMA 298:1171-9. 2007..Although beta-blockers improve symptoms and survival in adults with heart failure, little is known about these medications in children and adolescents... - Outcome of children with end-stage congenital heart disease waiting for cardiac transplantationSeema Mital
Division of Pediatric Cardiology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Heart Lung Transplant 22:147-53. 2003..End-stage congenital heart disease (CHD) is a major indication for pediatric cardiac transplantation. The objective of the study was to evaluate pre-transplant outcome of children with CHD... - Psychiatric disorders in youth with medically unexplained chest pain versus innocent heart murmurJoshua D Lipsitz
College of Physicians and Surgeons, Columbia University, New York, NY, USA
J Pediatr 160:320-4. 2012..To examine the prevalence of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition psychiatric disorders in youth with chest pain compared with a control sample with innocent heart murmur... - Echocardiographic analysis of ventricular geometry and function during repair of congenital septal defectsJoseph P Hart
Department of Surgery, Columbia College of Physicians and Surgeons, New York, New York 10032, USA
Ann Thorac Surg 77:53-60. 2004..Additional studies are needed to define changes in afterload and contractility as well as diastolic compliance and systolic mechanics... - Multicenter USA Amplatzer patent ductus arteriosus occlusion device trial: initial and one-year resultsRobert H Pass
Department of Pediatrics, Children s Hospital of New York, Presbyterian Hospital, Columbia University, New York, New York 10032, USA
J Am Coll Cardiol 44:513-9. 2004..We sought to review and report initial and one-year efficacy and safety results of the multicenter USA Amplatzer ductal occluder (ADO) device trial... - RAAS gene polymorphisms influence progression of pediatric hypertrophic cardiomyopathyBeth D Kaufman
Department of Pediatrics, Columbia University, New York, NY, 10032, USA
Hum Genet 122:515-23. 2007..05). Pro-LVH RAAS gene polymorphisms are associated with progressive septal hypertrophy and LVOT obstruction in children with HCM. Identification of RAAS modifier genes may help to risk-stratify patients with HCM... - Endovascular stent placement for venous obstruction after cardiac transplantation in children and young adultsAnitha Jayakumar
Division of Pediatric Cardiology, Department of Pediatrics, Children's Hospital of New York, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Catheter Cardiovasc Interv 56:383-6. 2002..Endovascular stent implantation for venous obstruction in patients following cardiac transplantation was safe and effective, allowing improved ease of catheterization for future posttransplantation monitoring and surveillance... - Endovascular stent implantation in the pulmonary arteries of infants and children without the use of a long vascular sheathRobert H Pass
Division of Pediatric Cardiology, Department of Pediatrics, Children s Hospital of New York New York Presbyterian Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Catheter Cardiovasc Interv 55:505-9. 2002..This technique is useful for the palliation of proximal pulmonary artery stenosis and is effective definitive treatment for peripheral pulmonary artery stenosis in small infants and children...
Research Grants
- Pediatric Heart Network: Follow-up of the Single Ventricle Reconstruction TrialWilliam Hellenbrand; Fiscal Year: 2007..The results of this multicenter, prospective study will provide important information regarding the optimal neonatal surgical intervention for this lesion. (End of Abstract) ..