Research Topics
| GEORGE M HRIPCSAKSummaryAffiliation: Columbia University Country: USA Publications
Research Grants
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Detail Information
Publications
Visualizing the operating range of a classification systemGeorge Hripcsak
Department of Biomedical Informatics, Columbia University Medical Center, 622 West 168th Street, VC5, New York, NY 10027, USA
J Am Med Inform Assoc 19:529-32. 2012..Graphing a prevalence-specific metric such as F-measure or the relative cost of errors over a wide range of prevalence allows a visualization of the performance of the system and a comparison of systems in different contexts...- A draft framework for measuring progress towards the development of a National Health Information InfrastructureDean F Sittig
Department of Medical Informatics, Northwest Permanente, P C, Portland, OR, USA
BMC Med Inform Decis Mak 5:14. 2005..We describe a conceptual framework to help measure progress toward that goal... - Characterizing environmental and phenotypic associations using information theory and electronic health recordsXiaoyan Wang
Dept of Biomedical Informatics, Columbia University, New York 10032, USA
BMC Bioinformatics 10:S13. 2009..In particular, some associations are indirect relations due to interdependencies among the data... - A reliability study for evaluating information extraction from radiology reportsG Hripcsak
Columbia University, New York, New York, USA
J Am Med Inform Assoc 6:143-50. 1999..To assess the reliability of a reference standard for an information extraction task... - Access to data: comparing AccessMed with Query by ReviewG Hripcsak
Department of Medical Informatics, Columbia Presbyterian Medical Center, New York, NY, USA
J Am Med Inform Assoc 3:288-99. 1996..To evaluate the performance of tools for authoring patient database queries... 
Mining complex clinical data for patient safety research: a framework for event discoveryGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, 622 West 168th Street, New York, NY 10032, USA
J Biomed Inform 36:120-30. 2003....- The United Hospital Fund meeting on evaluating health information exchangeGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
J Biomed Inform 40:S3-10. 2007..Unintended consequences should be monitored. A comprehensive study of return on investment requires an assessment of all effects. Program evaluation across several projects may help set future policy... - Emergency department access to a longitudinal medical recordGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, New York, NY, USA
J Am Med Inform Assoc 14:235-8. 2007.... - Using the Federated Council for Internal Medicine curricular guide and administrative codes to assess IM residents' breadth of experienceGeorge Hripcsak
Department of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA
Acad Med 79:557-63. 2004..To estimate internal medicine residents' breadth of experience using a published curricular guide and an electronic medical record... - Using discordance to improve classification in narrative clinical databases: an application to community-acquired pneumoniaGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
Comput Biol Med 37:296-304. 2007..In a study of pneumonia--in which the ICD9-CM coding was found to be very poor--the discordance measure was statistically significantly correlated with classification correctness (.45; 95% CI .15-.62)... - Modeling electronic discharge summaries as a simple temporal constraint satisfaction problemGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
J Am Med Inform Assoc 12:55-63. 2005..To model the temporal information contained in medical narrative reports as a simple temporal constraint satisfaction problem... - Agreement, the f-measure, and reliability in information retrievalGeorge Hripcsak
Department of Medical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
J Am Med Inform Assoc 12:296-8. 2005..Positive specific agreement-or the equivalent F-measure-may be an appropriate way to quantify interrater reliability and therefore to assess the reliability of a gold standard in these studies... - IAIMS architectureG Hripcsak
Department of Medical Informatics, Columbia Presbyterian Medical Center, New York, NY 10032, USA
J Am Med Inform Assoc 4:S20-30. 1997..Several IAIMS sites have adopted a client-server architecture, and some have adopted a three-tiered approach, separating user interface functions, application logic, and repositories... - Automated tuberculosis detectionG Hripcsak
Department of Medical Informatics, Columbia University, New York, USA
J Am Med Inform Assoc 4:376-81. 1997..To measure the accuracy of automated tuberculosis case detection... - Use of electronic clinical documentation: time spent and team interactionsGeorge Hripcsak
Department of Biomedical Informatics, Columbia University Medical Center, New York, USA
J Am Med Inform Assoc 18:112-7. 2011..To measure the time spent authoring and viewing documentation and to study patterns of usage in healthcare practice... - Reference standards, judges, and comparison subjects: roles for experts in evaluating system performanceGeorge Hripcsak
Department of Medical Informatics, Columbia University, New York, New York 10032, USA
J Am Med Inform Assoc 9:1-15. 2002..These are separate roles that have different implications for study design, metrics, and issues of reliability and validity. Diagrams help delineate the roles of experts in complex study designs... - Exploiting time in electronic health record correlationsGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, New York, New York 10032, USA
J Am Med Inform Assoc 18:i109-15. 2011..To demonstrate that a large, heterogeneous clinical database can reveal fine temporal patterns in clinical associations; to illustrate several types of associations; and to ascertain the value of exploiting time... - Syndromic surveillance using ambulatory electronic health recordsGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, New York, NY, 10032, USA
J Am Med Inform Assoc 16:354-61. 2009..To assess the performance of electronic health record data for syndromic surveillance and to assess the feasibility of broadly distributed surveillance... - Bias associated with mining electronic health recordsGeorge Hripcsak
Columbia University
J Biomed Discov Collab 6:48-52. 2011..Manual review revealed errors in both selecting and characterizing the cohort, and narrowing the cohort improved the result. Nevertheless, a significantly narrowed cohort might contain its own biases that would be difficult to estimate... - Use of natural language processing to translate clinical information from a database of 889,921 chest radiographic reportsGeorge Hripcsak
Department of Medical Informatics, Columbia University, 622 W 168th St, VC 5, New York, NY 10032, USA
Radiology 224:157-63. 2002..To evaluate translation of chest radiographic reports by using natural language processing and to compare the findings with those in the literature... - Measuring agreement in medical informatics reliability studiesGeorge Hripcsak
Department of Medical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
J Biomed Inform 35:99-110. 2002.... - Columbia University's Informatics for Diabetes Education and Telemedicine (IDEATel) project: technical implementationJustin Starren
Columbia University, New York, New York, USA
J Am Med Inform Assoc 9:25-36. 2002..With more than 400 HTUs installed, IDEATel has demonstrated the feasibility of large-scale home telemedicine... - Automated detection of adverse events using natural language processing of discharge summariesGenevieve B Melton
Department of Biomedical Informatics, Columbia University, 622 West 168th Street, Vanderbilt Clinic, 5th Floor, New York, NY 10032, USA
J Am Med Inform Assoc 12:448-57. 2005..CONCLUSION: NLP is an effective technique for detecting a broad range of adverse events in text documents and outperformed traditional and previous automated adverse event detection methods... - Of truth and pathways: chasing bits of information through myriads of articlesMichael Krauthammer
Department of Medical Informatics, Columbia University, New York, NY 10032, USA
Bioinformatics 18:S249-57. 2002..We hope that in the future such a model can be useful for automatically producing consensus views of molecular interaction data... - Gene symbol disambiguation using knowledge-based profilesHua Xu
Department of Biomedical Informatics, Columbia University, New York City, New York, USA
Bioinformatics 23:1015-22. 2007..Existing knowledge sources, such as Entrez Gene and the MEDLINE database, contain information concerning the characteristics of a particular gene that could be used to disambiguate gene symbols... - A temporal constraint structure for extracting temporal information from clinical narrativeLi Zhou
Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
J Biomed Inform 39:424-39. 2006..Placing data within the structure provides a foundational representation upon which further reasoning, including the addition of domain knowledge and other post-processing to implement an STP, can be accomplished... - The evaluation of a temporal reasoning system in processing clinical discharge summariesLi Zhou
Department of Biomedical Informatics, Columbia University, New York, NY, USA
J Am Med Inform Assoc 15:99-106. 2008..TimeText is a temporal reasoning system designed to represent, extract, and reason about temporal information in clinical text... - Repurposing the clinical record: can an existing natural language processing system de-identify clinical notes?Frances P Morrison
Columbia University Department of Biomedical Informatics, New York, NY, USA
J Am Med Inform Assoc 16:37-9. 2009..The MedLEE processor may be a good enhancement to other de-identification systems, both removing PHI and providing coded data from clinical text... - Using social network analysis within a department of biomedical informatics to induce a discussion of academic communities of practiceJacqueline Merrill
Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
J Am Med Inform Assoc 15:780-2. 2008..The findings will guide future direction and faculty recruitment efforts. Communities of practice present a novel view of interdisciplinarity in biomedical informatics... - Use abstracted patient-specific features to assist an information-theoretic measurement to assess similarity between medical casesHui Cao
Department of Biomedical Informatics, Columbia University, 622 W168th, VC5, New York, NY 10032, USA
J Biomed Inform 41:882-8. 2008..The developed metric, using a combination of abstracted disease, finding, procedure and medication features, achieved a correlation between 0.6012 and 0.6940 to experts... - The role of domain knowledge in automating medical text report classificationAdam B Wilcox
Department of Medical Informatics, University of Utah, Salt Lake City, USA
J Am Med Inform Assoc 10:330-8. 2003..To analyze the effect of expert knowledge on the inductive learning process in creating classifiers for medical text reports... - Assessing explicit error reporting in the narrative electronic medical record using keyword searchingHui Cao
Department of Medical Informatics, Columbia University, New York, NY, USA
J Biomed Inform 36:99-105. 2003..Identifying errors is a critical step for managing and preventing them. In this study, we assessed the explicit reporting of medical errors in the electronic record... - Active computerized pharmacovigilance using natural language processing, statistics, and electronic health records: a feasibility studyXiaoyan Wang
Department of Biomedical Informatics, Columbia University, 622 West 168 Street, VC5, New York, NY 10032, USA
J Am Med Inform Assoc 16:328-37. 2009..Our results demonstrate that the framework is feasible although there are some challenging issues. To the best of our knowledge, this is the first study using comprehensive unstructured data from the EHR for pharmacovigilance... - Design and analysis of controlled trials in naturally clustered environments: implications for medical informaticsJen Hsiang Chuang
Department of Medical Informatics, Columbia University, New York, New York 10032, USA
J Am Med Inform Assoc 9:230-8. 2002..Correlation must be taken into account in the analysis and in the sample-size calculations for cluster-randomized trials... - Temporal reasoning with medical data--a review with emphasis on medical natural language processingLi Zhou
Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
J Biomed Inform 40:183-202. 2007.... - Selecting information in electronic health records for knowledge acquisitionXiaoyan Wang
Department of Biomedical Informatics, Columbia University, New York, NY 10032, United States
J Biomed Inform 43:595-601. 2010..Further investigation of complementary methods, such as more sophisticated statistical methods, more complex temporal models and use of information from other knowledge sources, is needed... - Promoting patient safety and enabling evidence-based practice through informaticsSuzanne Bakken
Department of Nursing and Biomedical Informatics, Columbia University, New York, NY 10032, USA
Med Care 42:II49-56. 2004.... - An informatics infrastructure for patient safety and evidence-based practice in home healthcareSuzanne Bakken
Columbia University
J Healthc Qual 26:24-30. 2004..Resolution of these challenges requires commitment and collaboration among key stakeholders... - Columbia University's Informatics for Diabetes Education and Telemedicine (IDEATel) Project: rationale and designSteven Shea
Columbia University, New York, New York, USA
J Am Med Inform Assoc 9:49-62. 2002..The project is intended to provide data to help inform regulatory and reimbursement policies for electronically delivered health care services... - Automated encoding of clinical documents based on natural language processingCarol Friedman
Department of Biomedical Informatics, Columbia University, 622 West 168 Street, VC 5, New York, NY 10032, USA
J Am Med Inform Assoc 11:392-402. 2004..The aim of this study was to develop a method based on natural language processing (NLP) that automatically maps an entire clinical document to codes with modifiers and to quantitatively evaluate the method... - Mapping abbreviations to full forms in biomedical articlesHong Yu
Department of Medical Informatics, Columbia University, New York, New York 10032, USA
J Am Med Inform Assoc 9:262-72. 2002..To develop methods that automatically map abbreviations to their full forms in biomedical articles... - Terminology model discovery using natural language processing and visualization techniquesLi Zhou
Department of Biomedical Informatics, Columbia University, New York, NY, USA
J Biomed Inform 39:626-36. 2006..We believe that a general method based on NLP and information visualization will facilitate the modeling of medical terminologies... - A model for expanded public health reporting in the context of HIPAASoumitra Sengupta
Department of Biomedical Informatics, Columbia University, New York, NY, USA
J Am Med Inform Assoc 15:569-74. 2008..The appropriateness of these approaches varies with the definition of what data may be included, the requirements of the minimum necessary standard, the accounting of disclosures, and the feasibility of the approach... - Using empiric semantic correlation to interpret temporal assertions in clinical textsGeorge Hripcsak
Department of Biomedical Informatics, Columbia University, College of Physicians and Surgeons, 622 West 168 Street, VC 5, New York, NY 10032, USA
J Am Med Inform Assoc 16:220-7. 2009..To measure the uncertainty of temporal assertions like "3 weeks ago" in clinical texts... - A statistical methodology for analyzing co-occurrence data from a large sampleHui Cao
Department of Biomedical Informatics, 622 West 168th Street, VC 5, Columbia University, New York, NY 10032, USA
J Biomed Inform 40:343-52. 2007..We used linear regression to select the threshold in a reproducible fashion. In one experiment, we found that the method selected a threshold similar to that previously obtained by manually reviewing associations... - Large datasets in biomedicine: a discussion of salient analytic issuesAnshu Sinha
Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
J Am Med Inform Assoc 16:759-67. 2009..The authors further suggest that the community consider facilitating discussion through interdisciplinary panels, invited papers and curriculum enhancement to establish guidelines for analysis and reporting... - Clinical decision support and electronic prescribing systems: a time for responsible thought and actionRandolph A Miller
Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA
J Am Med Inform Assoc 12:403-9. 2005 - Detecting adverse events using information technologyDavid W Bates
Division of General Medicine, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
J Am Med Inform Assoc 10:115-28. 2003..Information technology techniques can detect some adverse events in a timely and cost-effective way, in some cases early enough to prevent patient harm... - Automated acquisition of disease drug knowledge from biomedical and clinical documents: an initial studyElizabeth S Chen
Clinical Informatics Research and Development, Partners HealthCare System, 93 Worcester Street, PO Box 81902, Wellesley, MA 02481, USA
J Am Med Inform Assoc 15:87-98. 2008..Explore the automated acquisition of knowledge in biomedical and clinical documents using text mining and statistical techniques to identify disease-drug associations... - An expert study evaluating the UMLS lexical metaschemaLi Zhang
Computer Science Department, New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA
Artif Intell Med 34:219-33. 2005.... - Inter-patient distance metrics using SNOMED CT defining relationshipsGenevieve B Melton
Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
J Biomed Inform 39:697-705. 2006..Ontology and information content principles may be potentially helpful tools for similarity metric development... - Evaluation of training with an annotation schema for manual annotation of clinical conditions from emergency department reportsWendy W Chapman
Department of Biomedical Informatics, University of Pittsburgh, 200 Meyran Avenue, M 183 VALE, Pittsburgh, PA 15260, United States
Int J Med Inform 77:107-13. 2008..Determine whether agreement among annotators improves after being trained to use an annotation schema that specifies: what types of clinical conditions to annotate, the linguistic form of the annotations, and which modifiers to include... - Development, implementation, and a cognitive evaluation of a definitional question answering system for physiciansHong Yu
Department of Health Sciences, University of Wisconsin Milwaukee, Enderis Hall 939, 2400 E Hartford Avenue, P O Box 413, Milwaukee, WI 53211, USA
J Biomed Inform 40:236-51. 2007.... - Developing common methods for evaluating health information exchangeGeorge Hripcsak
J Biomed Inform 40:S1-2. 2007 - Detecting adverse events for patient safety research: a review of current methodologiesHarvey J Murff
Department of Veterans Affairs, Tennessee Valley Healthcare System, GRECC, 1310 24th Avenue South, Nashville, TN 37212 2637, USA
J Biomed Inform 36:131-43. 2003..But these systems will perform optimally only if we improve our understanding of the fundamental nature of errors and the ways in which the human mind can naturally, but erroneously, contribute to the problems that we observe... - Comparing and consolidating two heuristic metaschemasYan Chen
New Jersey Institute of Technology, Newark, NJ 07102, USA
J Biomed Inform 41:293-317. 2008.... - Policy and the future of adverse event detection using information technologyDavid W Bates
Division of General Medicine, Department of Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA
J Am Med Inform Assoc 10:226-8. 2003 - A lexical metaschema for the UMLS semantic networkLi Zhang
Computer Science Department, New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA
Artif Intell Med 33:41-59. 2005..A new kind of metaschema, called the lexical metaschema, is derived from a lexical partition of the SN. The lexical metaschema is compared to previously derived metaschemas, e.g., the cohesive metaschema...
Research Grants
- DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESGeorge Hripcsak; Fiscal Year: 2009..We will evaluate the incremental benefit of structured data, narrative data, and temporally processed narrative data. ..
- DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESGeorge Hripcsak; Fiscal Year: 2005..abstract_text> ..
- DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESGeorge Hripcsak; Fiscal Year: 2002..6) Disseminate the methods and results--The methods and results will be disseminated via publications and a Web site, and tools will be made available. ..
- DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESGEORGE M HRIPCSAK; Fiscal Year: 2010....