GEORGE M HRIPCSAK

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Correlating electronic health record concepts with healthcare process events
    George Hripcsak
    Biomedical Informatics, Columbia University, New York, New York, USA
    J Am Med Inform Assoc 20:e311-8. 2013
  2. pmc Next-generation phenotyping of electronic health records
    George Hripcsak
    Biomedical Informatics, Columbia University, New York, NY 10027
    J Am Med Inform Assoc 20:117-21. 2013
  3. pmc Visualizing the operating range of a classification system
    George Hripcsak
    Department of Biomedical Informatics, Columbia University Medical Center, 622 West 168th Street, VC5, New York, NY 10027, USA
    J Am Med Inform Assoc 19:529-32. 2012
  4. pmc A draft framework for measuring progress towards the development of a National Health Information Infrastructure
    Dean F Sittig
    Department of Medical Informatics, Northwest Permanente, P C, Portland, OR, USA
    BMC Med Inform Decis Mak 5:14. 2005
  5. pmc Characterizing environmental and phenotypic associations using information theory and electronic health records
    Xiaoyan Wang
    Dept of Biomedical Informatics, Columbia University, New York 10032, USA
    BMC Bioinformatics 10:S13. 2009
  6. pmc Emergency department access to a longitudinal medical record
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, New York, NY, USA
    J Am Med Inform Assoc 14:235-8. 2007
  7. pmc Syndromic surveillance using ambulatory electronic health records
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, New York, NY, 10032, USA
    J Am Med Inform Assoc 16:354-61. 2009
  8. ncbi request reprint Using the Federated Council for Internal Medicine curricular guide and administrative codes to assess IM residents' breadth of experience
    George Hripcsak
    Department of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA
    Acad Med 79:557-63. 2004
  9. pmc Modeling electronic discharge summaries as a simple temporal constraint satisfaction problem
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
    J Am Med Inform Assoc 12:55-63. 2005
  10. pmc Access to data: comparing AccessMed with Query by Review
    G Hripcsak
    Department of Medical Informatics, Columbia Presbyterian Medical Center, New York, NY, USA
    J Am Med Inform Assoc 3:288-99. 1996

Research Grants

Detail Information

Publications60

  1. pmc Correlating electronic health record concepts with healthcare process events
    George Hripcsak
    Biomedical Informatics, Columbia University, New York, New York, USA
    J Am Med Inform Assoc 20:e311-8. 2013
    ..To study the relation between electronic health record (EHR) variables and healthcare process events...
  2. pmc Next-generation phenotyping of electronic health records
    George Hripcsak
    Biomedical Informatics, Columbia University, New York, NY 10027
    J Am Med Inform Assoc 20:117-21. 2013
    ....
  3. pmc Visualizing the operating range of a classification system
    George Hripcsak
    Department of Biomedical Informatics, Columbia University Medical Center, 622 West 168th Street, VC5, New York, NY 10027, USA
    J Am Med Inform Assoc 19:529-32. 2012
    ..Graphing a prevalence-specific metric such as F-measure or the relative cost of errors over a wide range of prevalence allows a visualization of the performance of the system and a comparison of systems in different contexts...
  4. pmc A draft framework for measuring progress towards the development of a National Health Information Infrastructure
    Dean F Sittig
    Department of Medical Informatics, Northwest Permanente, P C, Portland, OR, USA
    BMC Med Inform Decis Mak 5:14. 2005
    ..We describe a conceptual framework to help measure progress toward that goal...
  5. pmc Characterizing environmental and phenotypic associations using information theory and electronic health records
    Xiaoyan Wang
    Dept of Biomedical Informatics, Columbia University, New York 10032, USA
    BMC Bioinformatics 10:S13. 2009
    ..In particular, some associations are indirect relations due to interdependencies among the data...
  6. pmc Emergency department access to a longitudinal medical record
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, New York, NY, USA
    J Am Med Inform Assoc 14:235-8. 2007
    ....
  7. pmc Syndromic surveillance using ambulatory electronic health records
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, New York, NY, 10032, USA
    J Am Med Inform Assoc 16:354-61. 2009
    ..To assess the performance of electronic health record data for syndromic surveillance and to assess the feasibility of broadly distributed surveillance...
  8. ncbi request reprint Using the Federated Council for Internal Medicine curricular guide and administrative codes to assess IM residents' breadth of experience
    George Hripcsak
    Department of Biomedical Informatics, Columbia University Medical Center, New York, NY 10032, USA
    Acad Med 79:557-63. 2004
    ..To estimate internal medicine residents' breadth of experience using a published curricular guide and an electronic medical record...
  9. pmc Modeling electronic discharge summaries as a simple temporal constraint satisfaction problem
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
    J Am Med Inform Assoc 12:55-63. 2005
    ..To model the temporal information contained in medical narrative reports as a simple temporal constraint satisfaction problem...
  10. pmc Access to data: comparing AccessMed with Query by Review
    G Hripcsak
    Department of Medical Informatics, Columbia Presbyterian Medical Center, New York, NY, USA
    J Am Med Inform Assoc 3:288-99. 1996
    ..To evaluate the performance of tools for authoring patient database queries...
  11. pmc Agreement, the f-measure, and reliability in information retrieval
    George Hripcsak
    Department of Medical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
    J Am Med Inform Assoc 12:296-8. 2005
    ..Positive specific agreement-or the equivalent F-measure-may be an appropriate way to quantify interrater reliability and therefore to assess the reliability of a gold standard in these studies...
  12. pmc The United Hospital Fund meeting on evaluating health information exchange
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
    J Biomed Inform 40:S3-10. 2007
    ..Unintended consequences should be monitored. A comprehensive study of return on investment requires an assessment of all effects. Program evaluation across several projects may help set future policy...
  13. ncbi request reprint Using discordance to improve classification in narrative clinical databases: an application to community-acquired pneumonia
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
    Comput Biol Med 37:296-304. 2007
    ..In a study of pneumonia--in which the ICD9-CM coding was found to be very poor--the discordance measure was statistically significantly correlated with classification correctness (.45; 95% CI .15-.62)...
  14. ncbi request reprint Mining complex clinical data for patient safety research: a framework for event discovery
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, 622 West 168th Street, New York, NY 10032, USA
    J Biomed Inform 36:120-30. 2003
    ....
  15. pmc Use of electronic clinical documentation: time spent and team interactions
    George Hripcsak
    Department of Biomedical Informatics, Columbia University Medical Center, New York, USA
    J Am Med Inform Assoc 18:112-7. 2011
    ..To measure the time spent authoring and viewing documentation and to study patterns of usage in healthcare practice...
  16. ncbi request reprint Use of natural language processing to translate clinical information from a database of 889,921 chest radiographic reports
    George Hripcsak
    Department of Medical Informatics, Columbia University, 622 W 168th St, VC 5, New York, NY 10032, USA
    Radiology 224:157-63. 2002
    ..To evaluate translation of chest radiographic reports by using natural language processing and to compare the findings with those in the literature...
  17. pmc Bias associated with mining electronic health records
    George Hripcsak
    Columbia University
    J Biomed Discov Collab 6:48-52. 2011
    ..Manual review revealed errors in both selecting and characterizing the cohort, and narrowing the cohort improved the result. Nevertheless, a significantly narrowed cohort might contain its own biases that would be difficult to estimate...
  18. pmc Exploiting time in electronic health record correlations
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, New York, New York 10032, USA
    J Am Med Inform Assoc 18:i109-15. 2011
    ..To demonstrate that a large, heterogeneous clinical database can reveal fine temporal patterns in clinical associations; to illustrate several types of associations; and to ascertain the value of exploiting time...
  19. ncbi request reprint Measuring agreement in medical informatics reliability studies
    George Hripcsak
    Department of Medical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
    J Biomed Inform 35:99-110. 2002
    ....
  20. pmc A reliability study for evaluating information extraction from radiology reports
    G Hripcsak
    Columbia University, New York, New York, USA
    J Am Med Inform Assoc 6:143-50. 1999
    ..To assess the reliability of a reference standard for an information extraction task...
  21. pmc Reference standards, judges, and comparison subjects: roles for experts in evaluating system performance
    George Hripcsak
    Department of Medical Informatics, Columbia University, New York, New York 10032, USA
    J Am Med Inform Assoc 9:1-15. 2002
    ..These are separate roles that have different implications for study design, metrics, and issues of reliability and validity. Diagrams help delineate the roles of experts in complex study designs...
  22. pmc IAIMS architecture
    G Hripcsak
    Department of Medical Informatics, Columbia Presbyterian Medical Center, New York, NY 10032, USA
    J Am Med Inform Assoc 4:S20-30. 1997
    ..Several IAIMS sites have adopted a client-server architecture, and some have adopted a three-tiered approach, separating user interface functions, application logic, and repositories...
  23. pmc Automated tuberculosis detection
    G Hripcsak
    Department of Medical Informatics, Columbia University, New York, USA
    J Am Med Inform Assoc 4:376-81. 1997
    ..To measure the accuracy of automated tuberculosis case detection...
  24. pmc Columbia University's Informatics for Diabetes Education and Telemedicine (IDEATel) project: technical implementation
    Justin Starren
    Columbia University, New York, New York, USA
    J Am Med Inform Assoc 9:25-36. 2002
    ..With more than 400 HTUs installed, IDEATel has demonstrated the feasibility of large-scale home telemedicine...
  25. pmc Automated detection of adverse events using natural language processing of discharge summaries
    Genevieve B Melton
    Department of Biomedical Informatics, Columbia University, 622 West 168th Street, Vanderbilt Clinic, 5th Floor, New York, NY 10032, USA
    J Am Med Inform Assoc 12:448-57. 2005
    ..To determine whether natural language processing (NLP) can effectively detect adverse events defined in the New York Patient Occurrence Reporting and Tracking System (NYPORTS) using discharge summaries...
  26. ncbi request reprint Of truth and pathways: chasing bits of information through myriads of articles
    Michael Krauthammer
    Department of Medical Informatics, Columbia University, New York, NY 10032, USA
    Bioinformatics 18:S249-57. 2002
    ..We hope that in the future such a model can be useful for automatically producing consensus views of molecular interaction data...
  27. ncbi request reprint Gene symbol disambiguation using knowledge-based profiles
    Hua Xu
    Department of Biomedical Informatics, Columbia University, New York City, New York, USA
    Bioinformatics 23:1015-22. 2007
    ..Existing knowledge sources, such as Entrez Gene and the MEDLINE database, contain information concerning the characteristics of a particular gene that could be used to disambiguate gene symbols...
  28. pmc The evaluation of a temporal reasoning system in processing clinical discharge summaries
    Li Zhou
    Department of Biomedical Informatics, Columbia University, New York, NY, USA
    J Am Med Inform Assoc 15:99-106. 2008
    ..TimeText is a temporal reasoning system designed to represent, extract, and reason about temporal information in clinical text...
  29. ncbi request reprint A temporal constraint structure for extracting temporal information from clinical narrative
    Li Zhou
    Department of Biomedical Informatics, Columbia University, 622 West 168th Street, VC5, New York, NY 10032, USA
    J Biomed Inform 39:424-39. 2006
    ..Many temporal reasoning mechanisms use constraint-based approaches. Our previous research demonstrates that electronic discharge summaries can be modeled as a simple temporal problem (STP)...
  30. pmc Use abstracted patient-specific features to assist an information-theoretic measurement to assess similarity between medical cases
    Hui Cao
    Department of Biomedical Informatics, Columbia University, 622 W168th, VC5, New York, NY 10032, USA
    J Biomed Inform 41:882-8. 2008
    ..The developed metric, using a combination of abstracted disease, finding, procedure and medication features, achieved a correlation between 0.6012 and 0.6940 to experts...
  31. pmc Selecting information in electronic health records for knowledge acquisition
    Xiaoyan Wang
    Department of Biomedical Informatics, Columbia University, New York, NY 10032, United States
    J Biomed Inform 43:595-601. 2010
    ..Further investigation of complementary methods, such as more sophisticated statistical methods, more complex temporal models and use of information from other knowledge sources, is needed...
  32. pmc Using social network analysis within a department of biomedical informatics to induce a discussion of academic communities of practice
    Jacqueline Merrill
    Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
    J Am Med Inform Assoc 15:780-2. 2008
    ..The findings will guide future direction and faculty recruitment efforts. Communities of practice present a novel view of interdisciplinarity in biomedical informatics...
  33. pmc Repurposing the clinical record: can an existing natural language processing system de-identify clinical notes?
    Frances P Morrison
    Columbia University Department of Biomedical Informatics, New York, NY, USA
    J Am Med Inform Assoc 16:37-9. 2009
    ..The MedLEE processor may be a good enhancement to other de-identification systems, both removing PHI and providing coded data from clinical text...
  34. pmc Active computerized pharmacovigilance using natural language processing, statistics, and electronic health records: a feasibility study
    Xiaoyan Wang
    Department of Biomedical Informatics, Columbia University, 622 West 168 Street, VC5, New York, NY 10032, USA
    J Am Med Inform Assoc 16:328-37. 2009
    ..Our results demonstrate that the framework is feasible although there are some challenging issues. To the best of our knowledge, this is the first study using comprehensive unstructured data from the EHR for pharmacovigilance...
  35. pmc Design and analysis of controlled trials in naturally clustered environments: implications for medical informatics
    Jen Hsiang Chuang
    Department of Medical Informatics, Columbia University, New York, New York 10032, USA
    J Am Med Inform Assoc 9:230-8. 2002
    ..Correlation must be taken into account in the analysis and in the sample-size calculations for cluster-randomized trials...
  36. pmc Automated encoding of clinical documents based on natural language processing
    Carol Friedman
    Department of Biomedical Informatics, Columbia University, 622 West 168 Street, VC 5, New York, NY 10032, USA
    J Am Med Inform Assoc 11:392-402. 2004
    ..The aim of this study was to develop a method based on natural language processing (NLP) that automatically maps an entire clinical document to codes with modifiers and to quantitatively evaluate the method...
  37. ncbi request reprint An informatics infrastructure for patient safety and evidence-based practice in home healthcare
    Suzanne Bakken
    Columbia University
    J Healthc Qual 26:24-30. 2004
    ..Resolution of these challenges requires commitment and collaboration among key stakeholders...
  38. ncbi request reprint Terminology model discovery using natural language processing and visualization techniques
    Li Zhou
    Department of Biomedical Informatics, Columbia University, New York, NY, USA
    J Biomed Inform 39:626-36. 2006
    ..We believe that a general method based on NLP and information visualization will facilitate the modeling of medical terminologies...
  39. ncbi request reprint Promoting patient safety and enabling evidence-based practice through informatics
    Suzanne Bakken
    Department of Nursing and Biomedical Informatics, Columbia University, New York, NY 10032, USA
    Med Care 42:II49-56. 2004
    ....
  40. ncbi request reprint Assessing explicit error reporting in the narrative electronic medical record using keyword searching
    Hui Cao
    Department of Medical Informatics, Columbia University, New York, NY, USA
    J Biomed Inform 36:99-105. 2003
    ..Identifying errors is a critical step for managing and preventing them. In this study, we assessed the explicit reporting of medical errors in the electronic record...
  41. pmc The role of domain knowledge in automating medical text report classification
    Adam B Wilcox
    Department of Medical Informatics, University of Utah, Salt Lake City, USA
    J Am Med Inform Assoc 10:330-8. 2003
    ..To analyze the effect of expert knowledge on the inductive learning process in creating classifiers for medical text reports...
  42. pmc Mapping abbreviations to full forms in biomedical articles
    Hong Yu
    Department of Medical Informatics, Columbia University, New York, New York 10032, USA
    J Am Med Inform Assoc 9:262-72. 2002
    ..To develop methods that automatically map abbreviations to their full forms in biomedical articles...
  43. pmc Columbia University's Informatics for Diabetes Education and Telemedicine (IDEATel) Project: rationale and design
    Steven Shea
    Columbia University, New York, New York, USA
    J Am Med Inform Assoc 9:49-62. 2002
    ..The project is intended to provide data to help inform regulatory and reimbursement policies for electronically delivered health care services...
  44. ncbi request reprint Temporal reasoning with medical data--a review with emphasis on medical natural language processing
    Li Zhou
    Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
    J Biomed Inform 40:183-202. 2007
    ....
  45. pmc Using empiric semantic correlation to interpret temporal assertions in clinical texts
    George Hripcsak
    Department of Biomedical Informatics, Columbia University, College of Physicians and Surgeons, 622 West 168 Street, VC 5, New York, NY 10032, USA
    J Am Med Inform Assoc 16:220-7. 2009
    ..To measure the uncertainty of temporal assertions like "3 weeks ago" in clinical texts...
  46. pmc A statistical methodology for analyzing co-occurrence data from a large sample
    Hui Cao
    Department of Biomedical Informatics, 622 West 168th Street, VC 5, Columbia University, New York, NY 10032, USA
    J Biomed Inform 40:343-52. 2007
    ..We used linear regression to select the threshold in a reproducible fashion. In one experiment, we found that the method selected a threshold similar to that previously obtained by manually reviewing associations...
  47. pmc A model for expanded public health reporting in the context of HIPAA
    Soumitra Sengupta
    Department of Biomedical Informatics, Columbia University, New York, NY, USA
    J Am Med Inform Assoc 15:569-74. 2008
    ..The appropriateness of these approaches varies with the definition of what data may be included, the requirements of the minimum necessary standard, the accounting of disclosures, and the feasibility of the approach...
  48. pmc Large datasets in biomedicine: a discussion of salient analytic issues
    Anshu Sinha
    Department of Biomedical Informatics, Columbia University, New York, NY 10032, USA
    J Am Med Inform Assoc 16:759-67. 2009
    ..The authors further suggest that the community consider facilitating discussion through interdisciplinary panels, invited papers and curriculum enhancement to establish guidelines for analysis and reporting...
  49. pmc Clinical decision support and electronic prescribing systems: a time for responsible thought and action
    Randolph A Miller
    Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA
    J Am Med Inform Assoc 12:403-9. 2005
  50. pmc Automated acquisition of disease drug knowledge from biomedical and clinical documents: an initial study
    Elizabeth S Chen
    Clinical Informatics Research and Development, Partners HealthCare System, 93 Worcester Street, PO Box 81902, Wellesley, MA 02481, USA
    J Am Med Inform Assoc 15:87-98. 2008
    ..Explore the automated acquisition of knowledge in biomedical and clinical documents using text mining and statistical techniques to identify disease-drug associations...
  51. ncbi request reprint Evaluation of training with an annotation schema for manual annotation of clinical conditions from emergency department reports
    Wendy W Chapman
    Department of Biomedical Informatics, University of Pittsburgh, 200 Meyran Avenue, M 183 VALE, Pittsburgh, PA 15260, United States
    Int J Med Inform 77:107-13. 2008
    ..Determine whether agreement among annotators improves after being trained to use an annotation schema that specifies: what types of clinical conditions to annotate, the linguistic form of the annotations, and which modifiers to include...
  52. pmc Detecting adverse events using information technology
    David W Bates
    Division of General Medicine, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Am Med Inform Assoc 10:115-28. 2003
    ..Information technology techniques can detect some adverse events in a timely and cost-effective way, in some cases early enough to prevent patient harm...
  53. ncbi request reprint Development, implementation, and a cognitive evaluation of a definitional question answering system for physicians
    Hong Yu
    Department of Health Sciences, University of Wisconsin Milwaukee, Enderis Hall 939, 2400 E Hartford Avenue, P O Box 413, Milwaukee, WI 53211, USA
    J Biomed Inform 40:236-51. 2007
    ....
  54. ncbi request reprint An expert study evaluating the UMLS lexical metaschema
    Li Zhang
    Computer Science Department, New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA
    Artif Intell Med 34:219-33. 2005
    ..In this paper, a statistical analysis methodology is presented to evaluate the lexical metaschema based on a study involving a group of established UMLS experts...
  55. ncbi request reprint Detecting adverse events for patient safety research: a review of current methodologies
    Harvey J Murff
    Department of Veterans Affairs, Tennessee Valley Healthcare System, GRECC, 1310 24th Avenue South, Nashville, TN 37212 2637, USA
    J Biomed Inform 36:131-43. 2003
    ..But these systems will perform optimally only if we improve our understanding of the fundamental nature of errors and the ways in which the human mind can naturally, but erroneously, contribute to the problems that we observe...
  56. ncbi request reprint Comparing and consolidating two heuristic metaschemas
    Yan Chen
    New Jersey Institute of Technology, Newark, NJ 07102, USA
    J Biomed Inform 41:293-317. 2008
    ....
  57. ncbi request reprint Inter-patient distance metrics using SNOMED CT defining relationships
    Genevieve B Melton
    Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    J Biomed Inform 39:697-705. 2006
    ..Ontology and information content principles may be potentially helpful tools for similarity metric development...
  58. ncbi request reprint Developing common methods for evaluating health information exchange
    George Hripcsak
    J Biomed Inform 40:S1-2. 2007
  59. pmc Policy and the future of adverse event detection using information technology
    David W Bates
    Division of General Medicine, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Am Med Inform Assoc 10:226-8. 2003
  60. ncbi request reprint A lexical metaschema for the UMLS semantic network
    Li Zhang
    Computer Science Department, New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA
    Artif Intell Med 33:41-59. 2005
    ..A new kind of metaschema, called the lexical metaschema, is derived from a lexical partition of the SN. The lexical metaschema is compared to previously derived metaschemas, e.g., the cohesive metaschema...

Research Grants11

  1. DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASES
    George Hripcsak; Fiscal Year: 2009
    ..We will evaluate the incremental benefit of structured data, narrative data, and temporally processed narrative data. ..
  2. DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASES
    George Hripcsak; Fiscal Year: 2005
    ..abstract_text> ..
  3. DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASES
    George Hripcsak; Fiscal Year: 2002
    ..6) Disseminate the methods and results--The methods and results will be disseminated via publications and a Web site, and tools will be made available. ..
  4. DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASES
    GEORGE M HRIPCSAK; Fiscal Year: 2010
    ....