Mady Hornig

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Immune-mediated animal models of Tourette syndrome
    Mady Hornig
    Center for Infection and Immunity, Columbia University Mailman School of Public Health, New York, NY, USA
    Neurosci Biobehav Rev 37:1120-38. 2013
  2. pmc Spatiotemporal analysis of purkinje cell degeneration relative to parasagittal expression domains in a model of neonatal viral infection
    Brent L Williams
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th Street, Rm 1801, New York, NY 10032, USA
    J Virol 81:2675-87. 2007
  3. pmc Hippocampal poly(ADP-Ribose) polymerase 1 and caspase 3 activation in neonatal bornavirus infection
    Brent L Williams
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
    J Virol 82:1748-58. 2008
  4. pmc Nonparametric methods for the analysis of single-color pathogen microarrays
    Omar J Jabado
    Center for Infection and Immunity Mailman School of Public Health Columbia University New York, NY, USA
    BMC Bioinformatics 11:354. 2010
  5. pmc Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances
    Brent L Williams
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e24585. 2011
  6. doi request reprint Astrovirus encephalitis in boy with X-linked agammaglobulinemia
    Phenix lan Quan
    Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 16:918-25. 2010
  7. doi request reprint Borna disease virus - fact and fantasy
    W Ian Lipkin
    Center for Infection and Immunity, Columbia University Mailman School of Public Health, 722 W 168th St, 17th Floor, New York, NY 10032, United States
    Virus Res 162:162-72. 2011
  8. pmc Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5
    Joari De Miranda
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    FASEB J 23:1064-71. 2009
  9. doi request reprint Oxidative stress biomarkers in sporadic ALS
    Hiroshi Mitsumoto
    Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University Medical Center, New York, NY 10032, USA
    Amyotroph Lateral Scler 9:177-83. 2008
  10. pmc Bocavirus episome in infected human tissue contains non-identical termini
    Amit Kapoor
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e21362. 2011

Research Grants

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Immune-mediated animal models of Tourette syndrome
    Mady Hornig
    Center for Infection and Immunity, Columbia University Mailman School of Public Health, New York, NY, USA
    Neurosci Biobehav Rev 37:1120-38. 2013
    ..Immunologically-based animal models of TS are a potent tool for dissecting the pathogenesis of this serious neuropsychiatric syndrome...
  2. pmc Spatiotemporal analysis of purkinje cell degeneration relative to parasagittal expression domains in a model of neonatal viral infection
    Brent L Williams
    Jerome L and Dawn Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, 722 West 168th Street, Rm 1801, New York, NY 10032, USA
    J Virol 81:2675-87. 2007
    ..These findings suggest a differential vulnerability of PC subsets during the early stages of virus-induced neurodegeneration...
  3. pmc Hippocampal poly(ADP-Ribose) polymerase 1 and caspase 3 activation in neonatal bornavirus infection
    Brent L Williams
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 1801, New York, NY 10032, USA
    J Virol 82:1748-58. 2008
    ..These results implicate aberrant zinc homeostasis, PARP-1, and caspase 3 activation as contributing factors in hippocampal neurodegeneration in NBD...
  4. pmc Nonparametric methods for the analysis of single-color pathogen microarrays
    Omar J Jabado
    Center for Infection and Immunity Mailman School of Public Health Columbia University New York, NY, USA
    BMC Bioinformatics 11:354. 2010
    ..Exploratory analysis of fluorescent signal distribution in clinical samples has revealed deviations from normality, suggesting that distribution-free approaches should be applied...
  5. pmc Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances
    Brent L Williams
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e24585. 2011
    ..These results indicate a relationship between human intestinal gene expression and bacterial community structure and may provide insights into the pathophysiology of gastrointestinal disturbances in children with autism...
  6. doi request reprint Astrovirus encephalitis in boy with X-linked agammaglobulinemia
    Phenix lan Quan
    Columbia University, New York, New York 10032, USA
    Emerg Infect Dis 16:918-25. 2010
    ..Our findings expand the spectrum of causative agents associated with encephalitis and highlight unbiased molecular technology as a valuable tool for differential diagnosis of unexplained disease...
  7. doi request reprint Borna disease virus - fact and fantasy
    W Ian Lipkin
    Center for Infection and Immunity, Columbia University Mailman School of Public Health, 722 W 168th St, 17th Floor, New York, NY 10032, United States
    Virus Res 162:162-72. 2011
    ..This article reviews the history, molecular biology, epidemiology, and pathobiology of bornaviruses...
  8. pmc Astrocytes recognize intracellular polyinosinic-polycytidylic acid via MDA-5
    Joari De Miranda
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    FASEB J 23:1064-71. 2009
    ..Our results illustrate the intricacy of extracellular and intracellular ds-RNA recognition in viral infections of the central nervous system and indicate the importance of MDA-5 helicase as an intracellular ds-RNA sensor in astrocytes...
  9. doi request reprint Oxidative stress biomarkers in sporadic ALS
    Hiroshi Mitsumoto
    Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University Medical Center, New York, NY 10032, USA
    Amyotroph Lateral Scler 9:177-83. 2008
    ..ELISA may be reliable and thus useful in epidemiology studies requiring large numbers of samples to determine the significance of increased oxidative stress markers in SALS. Further studies are required...
  10. pmc Bocavirus episome in infected human tissue contains non-identical termini
    Amit Kapoor
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e21362. 2011
    ..Complete genomic sequence of the HBoV3 episome and its genomic termini will improve our understanding of HBoV replication mechanism and its pathogenesis...
  11. pmc Toll-like receptor 3 regulates neural stem cell proliferation by modulating the Sonic Hedgehog pathway
    Kavitha Yaddanapudi
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 6:e26766. 2011
    ....
  12. pmc Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza
    Gustavo Palacios
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA
    PLoS ONE 4:e8540. 2009
    ..Furthermore, no evidence was found for increased frequency of risk factors for H1N1pdm disease...
  13. pmc Heart and skeletal muscle inflammation of farmed salmon is associated with infection with a novel reovirus
    Gustavo Palacios
    Center for Infection and Immunity, Columbia University, New York, New York, United States of America
    PLoS ONE 5:e11487. 2010
    ....
  14. doi request reprint The role of microbes and autoimmunity in the pathogenesis of neuropsychiatric illness
    Mady Hornig
    Department of Epidemiology, Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Curr Opin Rheumatol 25:488-795. 2013
    ..To illustrate how microbes might participate in the pathogenesis of neuropsychiatric illness by triggering the production of autoantibodies that bind to brain targets...
  15. doi request reprint Interpregnancy interval and risk of autistic disorder
    Nina Gunnes
    From the aNorwegian Institute of Public Health, Oslo, Norway bDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY cNew York State Psychiatric Institute, New York, NY dCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY eDepartment of Global Public Health and Primary Care, University of Bergen, Bergen, Norway fCentre for Clinical Research, Haukeland University Hospital, Bergen, Norway gInstitute of Psychiatry, University of Oslo, Oslo, Norway and hNic Waals Institute, Lovisenberg Diakonale Hospital, Oslo, Norway
    Epidemiology 24:906-12. 2013
    ..A recent California study reported increased risk of autistic disorder in children conceived within a year after the birth of a sibling...
  16. pmc Novel borna virus in psittacine birds with proventricular dilatation disease
    Kirsi S Honkavuori
    Columbia University, New York, NY, USA
    Emerg Infect Dis 14:1883-6. 2008
    ..Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds...
  17. pmc Lack of association between measles virus vaccine and autism with enteropathy: a case-control study
    Mady Hornig
    Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 3:e3140. 2008
    ..Failure to replicate the original study design may contribute to continued public concern with respect to the safety of the measles, mumps, and rubella (MMR) vaccine...
  18. ncbi request reprint Metallothioneins and zinc dysregulation contribute to neurodevelopmental damage in a model of perinatal viral infection
    Brent L Williams
    Greene Infectious Disease Laboratory, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Brain Pathol 16:1-14. 2006
    ..Abnormal zinc metabolism and mechanisms of neuroplasticity may contribute to the pathogenesis of disease in this model, raising more general implications for neurodevelopmental damage following viral infections in early life...
  19. ncbi request reprint Psychotropic viruses
    W Ian Lipkin
    Greene ID Lab MSPH Columbia, 722 West 168th Street, Rm 1801, New York, New York 10032, USA
    Curr Opin Microbiol 7:420-5. 2004
    ..Here we review clinical and epidemiologic data concerning viral infection and mental illness, as well as animal models that provide insight into the myriad of mechanisms by which infection can cause brain dysfunction...
  20. ncbi request reprint Borna disease virus
    Mady Hornig
    Center for Immunopathogenesis and Infectious Diseases, Mailman School of Public Health, Columbia University, New York, New York 10025, USA
    J Neurovirol 9:259-73. 2003
    ....

Research Grants1

  1. MECHANISMS OF NEUROPATHOGENESIS IN BORNA DISEASE
    Mady Hornig; Fiscal Year: 2002
    ....