L J Hirsch

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy
    L J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Mailman School of Public Health, Columbia University, 710 W 168 St, Box NI 135, New York, NY 10032, USA
    Neurology 63:1022-6. 2004
  2. ncbi request reprint Focal motor seizures induced by alerting stimuli in critically ill patients
    Lawrence J Hirsch
    Department of Neurology, Comprehensive Epilepsy Center, Neurological Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Epilepsia 49:968-73. 2008
  3. doi request reprint Cross-sensitivity of skin rashes with antiepileptic drug use
    L J Hirsch
    Associate Clinical Comprehensive Epilepsy Center, Columbia University, Neurological Institute, New York, NY 10032, USA
    Neurology 71:1527-34. 2008
  4. ncbi request reprint Predictors of Lamotrigine-associated rash
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Mailman School of Public Health, Columbia University, 710 W 168th Street, NI 1 35, New York, NY 10032, U S A
    Epilepsia 47:318-22. 2006
  5. ncbi request reprint Effect of age and comedication on levetiracetam pharmacokinetics and tolerability
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Epilepsia 48:1351-9. 2007
  6. ncbi request reprint The current state of treatment of status epilepticus
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Columbia University Neurological Institute, Box NI 135, 710 West 168th Street, New York, NY 10032, USA
    Curr Neurol Neurosci Rep 2:345-56. 2002
  7. ncbi request reprint The ACNS subcommittee on research terminology for continuous EEG monitoring: proposed standardized terminology for rhythmic and periodic EEG patterns encountered in critically ill patients
    Lawrence J Hirsch
    Department of Neurology, Comprehensive Epilepsy Center, Columbia University, New York, New York, USA
    J Clin Neurophysiol 22:128-35. 2005
  8. ncbi request reprint Continuous EEG monitoring and midazolam infusion for refractory nonconvulsive status epilepticus
    J Claassen
    Department of Neurology, Division of Critical Care Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurology 57:1036-42. 2001
  9. pmc Clinical use of ictal SPECT in secondarily generalized tonic-clonic seizures
    G I Varghese
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Brain 132:2102-13. 2009
  10. ncbi request reprint Comparison and predictors of rash associated with 15 antiepileptic drugs
    H Arif
    Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York, NY 10032, USA
    Neurology 68:1701-9. 2007

Collaborators

Detail Information

Publications66

  1. ncbi request reprint Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy
    L J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Mailman School of Public Health, Columbia University, 710 W 168 St, Box NI 135, New York, NY 10032, USA
    Neurology 63:1022-6. 2004
    ..To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy...
  2. ncbi request reprint Focal motor seizures induced by alerting stimuli in critically ill patients
    Lawrence J Hirsch
    Department of Neurology, Comprehensive Epilepsy Center, Neurological Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    Epilepsia 49:968-73. 2008
    ....
  3. doi request reprint Cross-sensitivity of skin rashes with antiepileptic drug use
    L J Hirsch
    Associate Clinical Comprehensive Epilepsy Center, Columbia University, Neurological Institute, New York, NY 10032, USA
    Neurology 71:1527-34. 2008
    ..To determine rates of cross-sensitivity of rash among commonly used antiepileptic drugs (AEDs) in patients with epilepsy...
  4. ncbi request reprint Predictors of Lamotrigine-associated rash
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Mailman School of Public Health, Columbia University, 710 W 168th Street, NI 1 35, New York, NY 10032, U S A
    Epilepsia 47:318-22. 2006
    ..To determine the predictors of lamotrigine-associated rash (LTG-rash) and the incidence of serious and benign LTG-rash to individualize risk assessment in a given patient...
  5. ncbi request reprint Effect of age and comedication on levetiracetam pharmacokinetics and tolerability
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Epilepsia 48:1351-9. 2007
    ..To compare pharmacokinetics and tolerability of levetiracetam (LEV) in older versus younger adults...
  6. ncbi request reprint The current state of treatment of status epilepticus
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Columbia University Neurological Institute, Box NI 135, 710 West 168th Street, New York, NY 10032, USA
    Curr Neurol Neurosci Rep 2:345-56. 2002
    ..This article reviews these issues, concentrating on recent advances and practical issues related to the clinical care of patients with status epilepticus...
  7. ncbi request reprint The ACNS subcommittee on research terminology for continuous EEG monitoring: proposed standardized terminology for rhythmic and periodic EEG patterns encountered in critically ill patients
    Lawrence J Hirsch
    Department of Neurology, Comprehensive Epilepsy Center, Columbia University, New York, New York, USA
    J Clin Neurophysiol 22:128-35. 2005
  8. ncbi request reprint Continuous EEG monitoring and midazolam infusion for refractory nonconvulsive status epilepticus
    J Claassen
    Department of Neurology, Division of Critical Care Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurology 57:1036-42. 2001
    ..Titrating cIV-MDZ to burst suppression, more aggressive treatment with concurrent AED, or a longer period of initial treatment may reduce the high proportion of patients with RSE who relapse after cIV-MDZ is discontinued...
  9. pmc Clinical use of ictal SPECT in secondarily generalized tonic-clonic seizures
    G I Varghese
    Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06520 8018, USA
    Brain 132:2102-13. 2009
    ..These findings suggest that, with appropriate cautious interpretation, ictal SPECT in secondarily generalized seizures can help localize the region of seizure onset...
  10. ncbi request reprint Comparison and predictors of rash associated with 15 antiepileptic drugs
    H Arif
    Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York, NY 10032, USA
    Neurology 68:1701-9. 2007
    ..To determine predictors and relative incidence of antiepileptic drug (AED)-related rash in patients taking all common AEDs...
  11. ncbi request reprint Detection of electrographic seizures with continuous EEG monitoring in critically ill patients
    J Claassen
    Division of Critical Care Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, USA
    Neurology 62:1743-8. 2004
    ..To identify patients most likely to have seizures documented on continuous EEG (cEEG) monitoring and patients who require more prolonged cEEG to record the first seizure...
  12. ncbi request reprint Electrographic seizures and periodic discharges after intracerebral hemorrhage
    J Claassen
    Division of Stroke and Critical Care Neurology, Comprehensive Epilepsy Center, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA
    Neurology 69:1356-65. 2007
    ..To determine the frequency and significance of electrographic seizures and other EEG findings in patients with intracerebral hemorrhage (ICH)...
  13. doi request reprint Continuous electroencephalogram monitoring in the intensive care unit
    Daniel Friedman
    Department of Neurology, Comprehensive Epilepsy Center, Columbia University, NewYork City, New York, USA
    Anesth Analg 109:506-23. 2009
    ..The exact role and cost-effectiveness of cEEG at the current time remains unclear, but we believe it has significant potential to improve neurologic outcomes in a variety of settings...
  14. doi request reprint Intracranial multimodal monitoring for acute brain injury: a single institution review of current practices
    R Morgan Stuart
    Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurocrit Care 12:188-98. 2010
    ..Here we review our experience in a consecutive series of acutely brain injured patients who underwent multimodality monitoring...
  15. ncbi request reprint Stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs): a common EEG phenomenon in the critically ill
    Lawrence J Hirsch
    Comprehensive Epilepsy Center Critical Care Division, Department of Neurology, Columbia University, New York, New York 10032, USA
    Epilepsia 45:109-23. 2004
    ..To describe an underrecognized EEG phenomenon in critically ill patients undergoing continuous EEG monitoring (cEEG). We named these EEG patterns stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs)...
  16. ncbi request reprint Nonconvulsive seizures: developing a rational approach to the diagnosis and management in the critically ill population
    J Jirsch
    Comprehensive Epilepsy Center, Columbia University Medical Center, New York, NY, USA
    Clin Neurophysiol 118:1660-70. 2007
    ..This review surveys the evidence for and against NCSs causing neuronal injury, and attempts to develop a rational approach to the diagnosis and management of these seizures, particularly in the encephalopathic population...
  17. ncbi request reprint Psychiatric and behavioral side effects of the newer antiepileptic drugs in adults with epilepsy
    D Weintraub
    Department of Neurology, Columbia University Comprehensive Epilepsy Center, New York, NY, USA
    Epilepsy Behav 10:105-10. 2007
    ..Psychiatric/behavioral side effects (PSEs) are common in patients taking antiepileptic drugs (AEDs). The objective of the study described here was to compare the PSE profiles of the newer AEDs...
  18. ncbi request reprint Nonconvulsive status epilepticus after subarachnoid hemorrhage
    Lyle J Dennis
    Division of Critical Care Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    Neurosurgery 51:1136-43; discussion 1144. 2002
    ..We sought to determine the frequency and clinical features of NCSE among comatose patients with SAH...
  19. ncbi request reprint Continuous electroencephalogram monitoring in critically ill patients
    Nathalie Jette
    Comprehensive Epilepsy Center, Columbia University, 710 West 168th Street, Box NI 135, New York, NY 10032, USA
    Curr Neurol Neurosci Rep 5:312-21. 2005
    ..This article reviews the indications and recent advances in cEEG in critically ill patients. Continuous brain monitoring with cEEG is rapidly becoming the standard of care in critically ill patients with neurologic impairment...
  20. ncbi request reprint Cyclic electrographic seizures in critically ill patients
    David E Friedman
    Comprehensive Epilepsy Center, Columbia University Medical Center, New York, New York, U S A
    Epilepsia 49:281-7. 2008
    ..Compressed displays of EEG frequency spectra (such as compressed spectral array, CSA) can facilitate interpretation of continuous EEG by allowing the reader to observe on a single screen patterns evolving over many minutes or hours...
  21. ncbi request reprint Continuous EEG monitoring in the intensive care unit
    Lawrence J Hirsch
    Neurological Institute of New York, Comprehensive Epilepsy Center, Columbia University, New York, New York 10032, USA
    Am J Electroneurodiagnostic Technol 44:137-58. 2004
    ....
  22. ncbi request reprint Lamotrigine and its applications in the treatment of epilepsy and other neurological and psychiatric disorders
    Sheetal Malik
    Comprehensive Epilepsy Center, Columbia University Neurological Institute, Box NI 135, 710 West 168th Street, 7th Floor, New York, NY 10032, USA
    Expert Rev Neurother 6:1609-27. 2006
    ..Lamotrigine has demonstrated particular benefit in the treatment of women and elderly patients with epilepsy...
  23. ncbi request reprint Effect of antiepileptic drug comedication on lamotrigine clearance
    David Weintraub
    Columbia Comprehensive Epilepsy Center and Department of Neurology, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Arch Neurol 62:1432-6. 2005
    ..To investigate the effect of antiepileptic drug (AED) comedication, including all newer AEDs, on lamotrigine clearance (CL)...
  24. ncbi request reprint Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sample
    Jan Claassen
    Division of Stroke and Critical Care Neurology and Comprehensive Epilepsy Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Neurosurgery 61:60-4; discussion 64-5. 2007
    ..To identify the frequency of and impact on outcome of generalized convulsive status epilepticus (GCSE) among patients with nontraumatic subarachnoid hemorrhage (SAH)...
  25. ncbi request reprint Prognostic significance of continuous EEG monitoring in patients with poor-grade subarachnoid hemorrhage
    Jan Claassen
    Division of Stroke and Critical Care Neurology, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Neurocrit Care 4:103-12. 2006
    ..The objective of this study was to determine if continuous electroencephalogram (cEEG) monitoring results are predictive of 3-month outcome in critically ill patients with SAH...
  26. ncbi request reprint Continuous EEG monitoring in patients with subarachnoid hemorrhage
    Jan Claassen
    Comprehensive Epilepsy Center, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Neurophysiol 22:92-8. 2005
    ..CEEG findings may lead to therapeutic (e.g., antiepileptic medication, hypertensive therapy, angioplasty) or additional diagnostic interventions such as angiography, CT or MRI...
  27. doi request reprint Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsy
    Hiba Arif
    Comprehensive Epilepsy Center, Columbia University, Neurological Institute, 710 W 168th St, New York, NY 10032, USA
    Arch Neurol 67:408-15. 2010
    ..To compare the effectiveness of antiepileptic drugs (AEDs) for use in older adults with epilepsy...
  28. ncbi request reprint Intracortical electroencephalography in acute brain injury
    Allen Waziri
    Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Ann Neurol 66:366-77. 2009
    ..We hypothesized that bedside placement of an intracortical multicontact electrode would allow for improved monitoring of cortical potentials in critically ill neurological patients...
  29. ncbi request reprint A randomized, double-blind, placebo-controlled trial of donepezil to improve memory in epilepsy
    Marla J Hamberger
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Epilepsia 48:1283-91. 2007
    ..To determine whether an acetylcholinesterase inhibitor, such as donepezil, would improve memory or other cognitive/psychological functions in epilepsy patients with subjective memory complaints...
  30. ncbi request reprint Levetiracetam may be more effective for late-onset partial epilepsy
    Carl W Bazil
    Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York, NY 10032, USA
    Arch Neurol 59:1905-8. 2002
    ..Clinical experience suggests that certain individuals will respond to a given agent while others with the same seizure type will not...
  31. ncbi request reprint How long does it take to make an accurate diagnosis in an epilepsy monitoring unit?
    David E Friedman
    Neurological Institute, Comprehensive Epilepsy Center, Columbia University Medical Center, New York, New York, USA
    J Clin Neurophysiol 26:213-7. 2009
    ..Interictal electroencephalography alone cannot reliably distinguish between those with epileptic seizures and nonepileptic events...
  32. ncbi request reprint Tonic-absence seizures: an underrecognized seizure type
    Tina T Shih
    Columbia Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York Presbyterian Hospital, New York, New York 10032, USA
    Epilepsia 44:461-5. 2003
    ..In addition, these descriptions were formulated in the pre-EMU (Epilepsy Monitoring Unit) era, without benefit of video/clinical correlation. We now characterize this underrecognized seizure type...
  33. ncbi request reprint Treatment of status epilepticus: a survey of neurologists
    Jan Claassen
    Division of Critical Care Neurology, Department of Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, 710 West 168th Street, Unit 39, New York, NY 10032, USA
    J Neurol Sci 211:37-41. 2003
    ..New antiepileptic drugs (AEDs) have provided alternatives to traditional treatment paradigms for status epilepticus (SE)...
  34. ncbi request reprint Continuous electroencephalographic monitoring in critically ill patients with central nervous system infections
    Emmanuel Carrera
    Comprehensive Epilepsy Center, Columbia University Medical Center, 710 W 168th St, Box NI 135, New York, NY 10032, USA
    Arch Neurol 65:1612-8. 2008
    ..To determine the prevalence, predictors, and clinical significance of electrographic seizures (ESz) and other continuous electroencephalographic monitoring findings in critically ill patients with central nervous system infections...
  35. ncbi request reprint Efficacy of clobazam as add-on therapy for refractory epilepsy: experience at a US epilepsy center
    Maria A Montenegro
    Department of Neurology, Comprehensive Epilepsy Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Clin Neuropharmacol 31:333-8. 2008
    ..The objective of this study was to evaluate the usage patterns, efficacy, tolerability, and 1-year retention of CLB in patients with refractory epilepsy seen at a tertiary US epilepsy center...
  36. ncbi request reprint Quantitative continuous EEG for detecting delayed cerebral ischemia in patients with poor-grade subarachnoid hemorrhage
    Jan Claassen
    The Division of Stroke and Critical Care Neurology, Department of Neurology, Neurological Institute, Columbia University, New York, NY 10032, USA
    Clin Neurophysiol 115:2699-710. 2004
    ..The purpose of this study was to identify quantitative EEG (qEEG) parameters that are most sensitive and specific for the detection of DCI in stuporous or comatose SAH patients...
  37. ncbi request reprint Continuous EEG monitoring in the intensive care unit: an overview
    Lawrence J Hirsch
    Comprehensive Epilepsy Center, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    J Clin Neurophysiol 21:332-40. 2004
    ..Real-time detection of ischemia at a reversible stage is technologically feasible with CEEG and should be developed into a practical form for prevention of in-hospital infarction in the near future...
  38. ncbi request reprint Treatment of status epilepticus
    Hiba Arif
    Comprehensive Epilepsy Center, Columbia University, New York, New York, USA
    Semin Neurol 28:342-54. 2008
    ..In refractory SE, continuous EEG monitoring is required to recognize recurrence of seizure activity, as most seizures will be nonconvulsive...
  39. ncbi request reprint Diagnostic utility of an epilepsy monitoring unit
    Janice L Smolowitz
    Columbia University School of Nursing, Department of Neurology, New York, NY 10032, USA
    Am J Med Qual 22:117-22. 2007
    ..Admission resulted in change in treatment in 79%. This review documents the diagnostic utility of an epilepsy monitoring unit while highlighting that time since symptom onset to admission exceeded established guidelines...
  40. ncbi request reprint Bitemporal epileptiform discharges induced by bupropion: a case report
    G D Shah
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Clin Neuropharmacol 24:304-6. 2001
    ..This is the first well-documented case of epileptiform discharges induced by bupropion in humans...
  41. pmc Cortical and subcortical networks in human secondarily generalized tonic-clonic seizures
    H Blumenfeld
    Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520 8018, USA
    Brain 132:999-1012. 2009
    ..Understanding the networks involved in generalized tonic-clonic seizures can provide insights into mechanisms of behavioural changes, and may elucidate targets for improved therapies...
  42. ncbi request reprint Advances in the management of seizures and status epilepticus in critically ill patients
    Karine J Abou Khaled
    Comprehensive Epilepsy Center, Department of Neurology, Columbia University Neurological Institute, New York, NY 10032, USA
    Crit Care Clin 22:637-59; abstract viii. 2006
    ..This article discusses specific treatments and specific situations, such as hepatic and renal failure patients and organ transplant patients...
  43. ncbi request reprint Updates in the management of seizures and status epilepticus in critically ill patients
    Karine J Abou Khaled
    Department of Neurology, Comprehensive Epilepsy Center, Columbia University, New York, NY 10032, USA
    Neurol Clin 26:385-408, viii. 2008
    ..This article discusses specific treatments and specific situations, such as hepatic and renal failure patients and organ transplant patients...
  44. ncbi request reprint Which EEG patterns warrant treatment in the critically ill? Reviewing the evidence for treatment of periodic epileptiform discharges and related patterns
    Derek J Chong
    Columbia University Medical Center, New York, New York, USA
    J Clin Neurophysiol 22:79-91. 2005
    ..Recommendations for treatment are given, and a modification to current criteria for the diagnosis of nonconvulsive seizures is suggested...
  45. ncbi request reprint Inadequacy of standard screen resolution for localization of seizures recorded from intracranial electrodes
    Catherine A Schevon
    Comprehensive Epilepsy Center, Neurological Institute of New York, Columbia University, New York, New York 10016, USA
    Epilepsia 45:1453-8. 2004
    ..Alternatively, spectral analysis should be performed on recordings of neocortical seizures to detect high-frequency activity that may be missed on visual inspection...
  46. ncbi request reprint Video-EEG monitoring in the elderly: a review of 94 patients
    Alexandra E McBride
    Department of Neurology, Long Island Jewish Medical Center, New Hyde Park, NY, USA
    Epilepsia 43:165-9. 2002
    ..Few studies have assessed the characteristics of epileptic and nonepileptic seizures in this age group. Diagnostic evaluation with video-EEG monitoring is a means to distinguish these different types of events...
  47. doi request reprint Seizures and CNS hemorrhage: spontaneous intracerebral and aneurysmal subarachnoid hemorrhage
    Emily Gilmore
    Division of Critical Care Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurologist 16:165-75. 2010
    ..The deleterious effects of seizures on brain recovering from a recent injury have to be weighed against the deleterious effects of antiepileptic medications when making decisions on prophylaxis and treatment...
  48. ncbi request reprint Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: a systematic review
    Jan Claassen
    Department of Neurology, Division of Critical Care Neurology, and The Comprehensive Epilepsy Center, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Epilepsia 43:146-53. 2002
    ..This systematic review compares the efficacy of midazolam (MDL), propofol (PRO), and pentobarbital (PTB) for terminating seizures and improving outcome in RSE patients...
  49. ncbi request reprint Convulsive status epilepticus after ischemic stroke and intracerebral hemorrhage: frequency, predictors, and impact on outcome in a large administrative dataset
    Brian T Bateman
    Columbia Presbyterian Medical College for Physicians and Surgeons, Columbia University, New York, NY, USA
    Neurocrit Care 7:187-93. 2007
    ..We examined the occurrence of GCSE in acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) using a large discharge database...
  50. ncbi request reprint Literature review, case report, and expert discussion of prolonged refractory status epilepticus
    T K Robakis
    Comprehensive Epilepsy Center, Columbia University, New York, NY 10032, USA
    Neurocrit Care 4:35-46. 2006
    ..The patient eventually suffered a cardiac arrest but was resuscitated as requested by the family. Seizures then stopped, and the patient has remained in a persistent vegetative state since...
  51. ncbi request reprint Continuous electroencephalogram monitoring in the critically ill
    John J Wittman
    Comprehensive Epilepsy Center, Columbia University, New York, NY 10032, USA
    Neurocrit Care 2:330-41. 2005
    ..This article discusses findings with cEEG to date, pitfalls in performing and interpreting these studies, and where we should turn our attention with this underutilized brain monitoring technique...
  52. doi request reprint Continuous electroencephalography in the medical intensive care unit
    Mauro Oddo
    Department of Neurology, Division of Critical Care, Neurological Institute, Columbia University Medical Center, New York, New York, USA
    Crit Care Med 37:2051-6. 2009
    ..To examine predictors and the prognostic value of electrographic seizures (ESZs) and periodic epileptiform discharges (PEDs) in medical intensive care unit (MICU) patients without a primary acute neurologic condition...
  53. ncbi request reprint Heart rate and EKG changes in 102 seizures: analysis of influencing factors
    Christian Opherk
    The Columbia University Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York Presbyterian Hospital, New York, USA
    Epilepsy Res 52:117-27. 2002
    ..Since cardiac arrhythmia may be a responsible factor, we sought to determine the prevalence of significant EKG abnormalities during and immediately after epileptic seizures, and to identify risk factors for these changes...
  54. ncbi request reprint Topiramate for the treatment of epilepsy and other nervous system disorders
    Leonie van Passel
    Comprehensive Epilepsy Center, Neurological Institute, Columbia University, Box NI 135, New York, NY 10032, USA
    Expert Rev Neurother 6:19-31. 2006
    ..Paresthesias and cognitive side effects are the most common troublesome adverse effects. Recent trends towards lower doses may help achieve the best combination of efficacy and tolerability...
  55. ncbi request reprint Predictors and clinical impact of epilepsy after subarachnoid hemorrhage
    J Claassen
    Division of Critical Care Neurology, The Comprehensive Epilepsy Center, Department of Neurology, College of Physicians and Surgeons, School of Public Health, Columbia University, New York, NY, USA
    Neurology 60:208-14. 2003
    ..To determine the frequency, predictors, and impact on outcome of epilepsy developing during the first year after subarachnoid hemorrhage (SAH)...
  56. ncbi request reprint Effects of incorporating memory confidence ratings and language handicap modifications on intracarotid amobarbital procedure (Wada test) memory asymmetry scores
    M J Hamberger
    Department of Neurology, College of Physicians and Surgeons of Columbia University, Columbia Presbyterian Medical Center, New York, New York, USA
    Epilepsia 40:1286-91. 1999
    ..e., adding a point to the memory score with anesthetization of the language-dominant hemisphere), both of which could be applied to most IAP protocols despite variations in testing methods among epilepsy surgery programs...
  57. pmc Abbreviated report of the NIH/NINDS workshop on sudden unexpected death in epilepsy
    L J Hirsch
    Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York, NY, USA
    Neurology 76:1932-8. 2011
    ..With the expansion of clinical, genetic, and basic science research, there is reasonable hope of advancing our understanding of SUDEP and ultimately our ability to prevent it...
  58. doi request reprint Patient-reported cognitive side effects of antiepileptic drugs: predictors and comparison of all commonly used antiepileptic drugs
    Hiba Arif
    Comprehensive Epilepsy Center, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Epilepsy Behav 14:202-9. 2009
    ..They are least likely to be reported with gabapentin, valproate, lamotrigine, carbamazepine, and levetiracetam...
  59. ncbi request reprint Can sudden unexplained death in epilepsy be prevented?
    Lawrence J Hirsch
    Department of Neurology, College of Physicians and Surgeons, New York City, NY 10032, USA
    Lancet 364:2157-8. 2004
  60. ncbi request reprint Absence epilepsy with onset before age three years: could this be Glut-1 deficiency syndrome (De Vivo syndrome)?
    Lawrence J Hirsch
    Epilepsia 45:92-3. 2004
  61. ncbi request reprint Frequency and predictors of nonconvulsive seizures during continuous electroencephalographic monitoring in critically ill children
    Nathalie Jette
    Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Arch Neurol 63:1750-5. 2006
    ..To determine the incidence, predictors, and timing of nonconvulsive seizures (NCSz) during continuous electroencephalographic monitoring (cEEG) in critically ill children...
  62. ncbi request reprint Facial emotion recognition after curative nondominant temporal lobectomy in patients with mesial temporal sclerosis
    Shearwood McClelland
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Epilepsia 47:1337-42. 2006
    ..The authors performed this study to test this hypothesis in a uniformly seizure-free postsurgical population...
  63. ncbi request reprint Ictal heart rate differentiates epileptic from non-epileptic seizures
    Christian Opherk
    Department of Medicine, University of Heidelberg, Heidelberg, Germany
    Neurology 58:636-8. 2002
    ..It was concluded that documenting an increase in HR during a spell of unresponsiveness usually can distinguish between epileptic and psychogenic causes...
  64. ncbi request reprint In nonconvulsive status epilepticus (NCSE), treat to burst-suppression: pro and con
    Kenneth G Jordan
    Jordan NeuroScience, Inc, San Bernardino, California 92404, USA
    Epilepsia 47:41-5. 2006
    ..It remains unclear if nonconvulsive seizures cause permanent neuronal injury. Nonconvulsive seizures should be diagnosed and treated as quickly as possible,but with non-coma-inducing treatments in most cases [corrected]..
  65. ncbi request reprint Nonconvulsive status epilepticus in children: clinical and EEG characteristics
    Stacey K H Tay
    Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
    Epilepsia 47:1504-9. 2006
    ..Nonconvulsive status epilepticus (NCSE) is a highly heterogeneous clinical condition that is understudied in the pediatric population...
  66. ncbi request reprint Brain monitoring: the next frontier of ICU monitoring
    Lawrence J Hirsch
    J Clin Neurophysiol 21:305-6. 2004