Elizabeth Hillman

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Assessment of an in situ temporal calibration method for time-resolved optical tomography
    Jeremy C Hebden
    University College London, Department of Medical Physics and Bioengineering, 11 20 Capper Street, London WC1E 6JA, UK
    J Biomed Opt 8:87-92. 2003
  2. pmc In vivo optical imaging and dynamic contrast methods for biomedical research
    Elizabeth M C Hillman
    Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, and Columbia University in the City of New York, New York, NY 10027, USA
    Philos Transact A Math Phys Eng Sci 369:4620-43. 2011
  3. pmc Depth-resolved optical imaging of transmural electrical propagation in perfused heart
    Elizabeth M C Hillman
    Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, Columbia University, 1210 Amsterdam Avenue, New York, NY 10027, USA
    Opt Express 15:17827-41. 2007
  4. pmc Optical brain imaging in vivo: techniques and applications from animal to man
    Elizabeth M C Hillman
    Columbia University, Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, 351ET, 1210 Amsterdam Avenue, New York, New York 10027, USA
    J Biomed Opt 12:051402. 2007
  5. pmc Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation
    Elizabeth M C Hillman
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    Neuroimage 35:89-104. 2007
  6. pmc Simultaneous multiwavelength laminar optical tomography
    Sean A Burgess
    Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Opt Lett 33:2710-2. 2008
  7. pmc High-speed vascular dynamics of the hemodynamic response
    Brenda R Chen
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Neuroimage 54:1021-30. 2011
  8. ncbi request reprint Laminar optical tomography: demonstration of millimeter-scale depth-resolved imaging in turbid media
    Elizabeth M C Hillman
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Lett 29:1650-2. 2004
  9. pmc Ultra-fast multispectral optical imaging of cortical oxygenation, blood flow, and intracellular calcium dynamics
    Matthew B Bouchard
    Laboratory for Functional Optical Imaging, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA
    Opt Express 17:15670-8. 2009
  10. pmc Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage
    William S Blaner
    Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA
    Biochim Biophys Acta 1791:467-73. 2009

Detail Information

Publications17

  1. ncbi request reprint Assessment of an in situ temporal calibration method for time-resolved optical tomography
    Jeremy C Hebden
    University College London, Department of Medical Physics and Bioengineering, 11 20 Capper Street, London WC1E 6JA, UK
    J Biomed Opt 8:87-92. 2003
    ..The effectiveness of the method is briefly demonstrated by imaging a solid object with tissue-equivalent optical properties...
  2. pmc In vivo optical imaging and dynamic contrast methods for biomedical research
    Elizabeth M C Hillman
    Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, and Columbia University in the City of New York, New York, NY 10027, USA
    Philos Transact A Math Phys Eng Sci 369:4620-43. 2011
    ....
  3. pmc Depth-resolved optical imaging of transmural electrical propagation in perfused heart
    Elizabeth M C Hillman
    Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, Columbia University, 1210 Amsterdam Avenue, New York, NY 10027, USA
    Opt Express 15:17827-41. 2007
    ..We demonstrate that LOT can clearly resolve the direction of propagation of electrical waves within the cardiac wall, and that the dynamics observed agree well with the model of electrical propagation in rat ventricular tissue...
  4. pmc Optical brain imaging in vivo: techniques and applications from animal to man
    Elizabeth M C Hillman
    Columbia University, Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, 351ET, 1210 Amsterdam Avenue, New York, New York 10027, USA
    J Biomed Opt 12:051402. 2007
    ..In summary, it is shown that optical brain imaging continues to grow and evolve, embracing new technologies and advancing to address ever more complex and important neuroscience questions...
  5. pmc Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulation
    Elizabeth M C Hillman
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    Neuroimage 35:89-104. 2007
    ....
  6. pmc Simultaneous multiwavelength laminar optical tomography
    Sean A Burgess
    Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Opt Lett 33:2710-2. 2008
    ..The system design and phantom validation studies are presented...
  7. pmc High-speed vascular dynamics of the hemodynamic response
    Brenda R Chen
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Neuroimage 54:1021-30. 2011
    ..Our results advance the fundamental understanding of the hemodynamic response, as well as our ability to evaluate potential cellular mechanisms for their involvement in neurovascular coupling...
  8. ncbi request reprint Laminar optical tomography: demonstration of millimeter-scale depth-resolved imaging in turbid media
    Elizabeth M C Hillman
    Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Opt Lett 29:1650-2. 2004
    ..System design and image reconstruction techniques are described, along with simulation and phantom results that demonstrate the characteristics and limitations of system accuracy and resolution...
  9. pmc Ultra-fast multispectral optical imaging of cortical oxygenation, blood flow, and intracellular calcium dynamics
    Matthew B Bouchard
    Laboratory for Functional Optical Imaging, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA
    Opt Express 17:15670-8. 2009
    ....
  10. pmc Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage
    William S Blaner
    Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA
    Biochim Biophys Acta 1791:467-73. 2009
    ..Collectively, the available information suggests that HSC lipid droplets are specialized organelles for hepatic retinoid storage and that loss of HSC lipid droplets may contribute to the development of hepatic disease...
  11. pmc A system for high-resolution depth-resolved optical imaging of fluorescence and absorption contrast
    Baohong Yuan
    Department of Biomedical Engineering, Laboratory for Functional Optical Imaging, Columbia University, New York 10027, USA
    Rev Sci Instrum 80:043706. 2009
    ..In this paper, we provide a detailed description of a new LOT system design capable of imaging both absorption and fluorescence contrast, and present characterization of its performance using phantom studies...
  12. pmc Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortex
    Anna Devor
    Martinos Center for Biomedical Imaging, Stroke and Neurovascular Regulation Laboratory, Charlestown, Massachusetts 02129, USA
    J Neurosci 28:14347-57. 2008
    ..We propose that other factors, such as neuronal (and glial) release of messenger molecules, might play a dominant role in the regulation of blood flow in vivo in response to a physiological stimulus...
  13. ncbi request reprint Optimal linear inverse solution with multiple priors in diffuse optical tomography
    Ang Li
    Department of Physics Tufts University, Medford, Massachusetts 02155, USA
    Appl Opt 44:1948-56. 2005
    ..Simulations are performed to demonstrate the significant improvement in image quality afforded by combining spatial and spectral priors...
  14. pmc Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signal
    Anna Devor
    Department of Neurosciences, University of California, San Diego, California 92093, USA
    J Neurosci 27:4452-9. 2007
    ....
  15. ncbi request reprint Diffuse optical tomography with spectral constraints and wavelength optimization
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Appl Opt 44:2082-93. 2005
    ..Here the technique is described and tested in detail, and optimum wavelength sets for a broad range of chromophore combinations are discovered and analyzed...
  16. ncbi request reprint Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 28:2339-41. 2003
    ..Application of these concepts should significantly improve the fidelity of continuous-wave diffuse near-infrared optical tomography in tissues...
  17. ncbi request reprint Effective scattering coefficient of the cerebral spinal fluid in adult head models for diffuse optical imaging
    Anna Custo
    Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    Appl Opt 45:4747-55. 2006
    ..Our findings lead us to expect that the diffusion approximation will be valid even in the presence of the CSF, with consequences for faster solution of the inverse problem...

Research Grants6

  1. A Depth-resolved Voltage Sensitive Dye Imaging System
    Elizabeth Hillman; Fiscal Year: 2007
    ..The effects of abnormal pathologies on neurovascular coupling could provide new insights for treatment and prevention. The new system could also find applications in ocular, dermal, endoscopic and tumor imaging. ..
  2. In-vivo optical imaging of neurovascular coupling and cerebral metabolism
    Elizabeth Hillman; Fiscal Year: 2009
    ....
  3. In-vivo optical imaging of neurovascular coupling and cerebral metabolism
    Elizabeth M C Hillman; Fiscal Year: 2010
    ....
  4. In-vivo optical imaging of neurovascular coupling and cerebral metabolism
    Elizabeth Hillman; Fiscal Year: 2009
    ....