Research Topics
| Elizabeth HillmanSummaryAffiliation: Columbia University Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Assessment of an in situ temporal calibration method for time-resolved optical tomographyJeremy C Hebden
University College London, Department of Medical Physics and Bioengineering, 11 20 Capper Street, London WC1E 6JA, UK
J Biomed Opt 8:87-92. 2003..The effectiveness of the method is briefly demonstrated by imaging a solid object with tissue-equivalent optical properties...
In vivo optical imaging and dynamic contrast methods for biomedical researchElizabeth M C Hillman
Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, and Columbia University in the City of New York, New York, NY 10027, USA
Philos Trans A Math Phys Eng Sci 369:4620-43. 2011....- Depth-resolved optical imaging of transmural electrical propagation in perfused heartElizabeth M C Hillman
Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, Columbia University, 1210 Amsterdam Avenue, New York, NY 10027, USA
Opt Express 15:17827-41. 2007..We demonstrate that LOT can clearly resolve the direction of propagation of electrical waves within the cardiac wall, and that the dynamics observed agree well with the model of electrical propagation in rat ventricular tissue... - Optical brain imaging in vivo: techniques and applications from animal to manElizabeth M C Hillman
Columbia University, Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, 351ET, 1210 Amsterdam Avenue, New York, New York 10027, USA
J Biomed Opt 12:051402. 2007..In summary, it is shown that optical brain imaging continues to grow and evolve, embracing new technologies and advancing to address ever more complex and important neuroscience questions... - Depth-resolved optical imaging and microscopy of vascular compartment dynamics during somatosensory stimulationElizabeth M C Hillman
Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
Neuroimage 35:89-104. 2007.... - Simultaneous multiwavelength laminar optical tomographySean A Burgess
Laboratory for Functional Optical Imaging, Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
Opt Lett 33:2710-2. 2008..The system design and phantom validation studies are presented... - High-speed vascular dynamics of the hemodynamic responseBrenda R Chen
Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
Neuroimage 54:1021-30. 2011..Our results advance the fundamental understanding of the hemodynamic response, as well as our ability to evaluate potential cellular mechanisms for their involvement in neurovascular coupling... - Laminar optical tomography: demonstration of millimeter-scale depth-resolved imaging in turbid mediaElizabeth M C Hillman
Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts 02129, USA
Opt Lett 29:1650-2. 2004..System design and image reconstruction techniques are described, along with simulation and phantom results that demonstrate the characteristics and limitations of system accuracy and resolution... - Ultra-fast multispectral optical imaging of cortical oxygenation, blood flow, and intracellular calcium dynamicsMatthew B Bouchard
Laboratory for Functional Optical Imaging, Departments of Biomedical Engineering and Radiology, Columbia University, New York, NY 10027, USA
Opt Express 17:15670-8. 2009.... - Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storageWilliam S Blaner
Department of Medicine, Columbia University, 630 W 168th St, New York, NY 10032, USA
Biochim Biophys Acta 1791:467-73. 2009..Collectively, the available information suggests that HSC lipid droplets are specialized organelles for hepatic retinoid storage and that loss of HSC lipid droplets may contribute to the development of hepatic disease... - A system for high-resolution depth-resolved optical imaging of fluorescence and absorption contrastBaohong Yuan
Department of Biomedical Engineering, Laboratory for Functional Optical Imaging, Columbia University, New York 10027, USA
Rev Sci Instrum 80:043706. 2009..In this paper, we provide a detailed description of a new LOT system design capable of imaging both absorption and fluorescence contrast, and present characterization of its performance using phantom studies... - Stimulus-induced changes in blood flow and 2-deoxyglucose uptake dissociate in ipsilateral somatosensory cortexAnna Devor
Martinos Center for Biomedical Imaging, Stroke and Neurovascular Regulation Laboratory, Charlestown, Massachusetts 02129, USA
J Neurosci 28:14347-57. 2008..We propose that other factors, such as neuronal (and glial) release of messenger molecules, might play a dominant role in the regulation of blood flow in vivo in response to a physiological stimulus... - Optimal linear inverse solution with multiple priors in diffuse optical tomographyAng Li
Department of Physics Tufts University, Medford, Massachusetts 02155, USA
Appl Opt 44:1948-56. 2005..Simulations are performed to demonstrate the significant improvement in image quality afforded by combining spatial and spectral priors... - Suppressed neuronal activity and concurrent arteriolar vasoconstriction may explain negative blood oxygenation level-dependent signalAnna Devor
Department of Neurosciences, University of California, San Diego, California 92093, USA
J Neurosci 27:4452-9. 2007.... - Diffuse optical tomography with spectral constraints and wavelength optimizationAlper Corlu
Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Appl Opt 44:2082-93. 2005..Here the technique is described and tested in detail, and optimum wavelength sets for a broad range of chromophore combinations are discovered and analyzed... - Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomographyAlper Corlu
Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Opt Lett 28:2339-41. 2003..Application of these concepts should significantly improve the fidelity of continuous-wave diffuse near-infrared optical tomography in tissues... - Effective scattering coefficient of the cerebral spinal fluid in adult head models for diffuse optical imagingAnna Custo
Computer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
Appl Opt 45:4747-55. 2006..Our findings lead us to expect that the diffusion approximation will be valid even in the presence of the CSF, with consequences for faster solution of the inverse problem...
Research Grants
- A Depth-resolved Voltage Sensitive Dye Imaging SystemElizabeth Hillman; Fiscal Year: 2007..The effects of abnormal pathologies on neurovascular coupling could provide new insights for treatment and prevention. The new system could also find applications in ocular, dermal, endoscopic and tumor imaging. ..
- In-vivo optical imaging of neurovascular coupling and cerebral metabolismElizabeth Hillman; Fiscal Year: 2009....
- In-vivo optical imaging of neurovascular coupling and cerebral metabolismElizabeth M C Hillman; Fiscal Year: 2010....
- In-vivo optical imaging of neurovascular coupling and cerebral metabolismElizabeth Hillman; Fiscal Year: 2009....