Dale Hesdorffer

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. doi request reprint Long-term psychiatric outcomes following traumatic brain injury: a review of the literature
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, and Department of Epidemiology, Mailman School of Public Health, New York, NY 10032, USA
    J Head Trauma Rehabil 24:452-9. 2009
  2. ncbi request reprint Are certain diuretics also anticonvulsants?
    D C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
    Ann Neurol 50:458-62. 2001
  3. ncbi request reprint Marked improvement in adherence to traumatic brain injury guidelines in United States trauma centers
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, New York, NY, USA
    J Trauma 63:841-7; discussion 847-8. 2007
  4. doi request reprint Status epilepticus without an underlying cause and risk of death: a population-based study
    Giancarlo Logroscino
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 10015, USA
    Arch Neurol 65:221-4. 2008
  5. doi request reprint Estimating the incidence of first unprovoked seizure and newly diagnosed epilepsy in the low-income urban community of Northern Manhattan, New York City
    Emma K T Benn
    Gertrude H Sergievsky Center, Columbia University, New York, New York 10032, USA
    Epilepsia 49:1431-9. 2008
  6. doi request reprint Suicidal ideation and behavior screening in intractable focal epilepsy eligible for drug trials
    Dale C Hesdorffer
    GH Sergievsky Center and Department of Epidemiology, Columbia University, New York, New York 10032, USA
    Epilepsia 54:879-87. 2013
  7. doi request reprint Surveillance of epilepsy and prevention of epilepsy and its sequelae: lessons from the Institute of Medicine report
    Dale C Hesdorffer
    Department of Epidemiology, Gertrude H Sergievsky Center, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Curr Opin Neurol 26:168-73. 2013
  8. pmc Research implications of the Institute of Medicine Report, Epilepsy Across the Spectrum: Promoting Health and Understanding
    Dale C Hesdorffer
    GH Sergievksky Center, Columbia University, New York, New York 10024, USA
    Epilepsia 54:207-16. 2013
  9. doi request reprint Sudden unexpected death in epilepsy. Potential role of antiepileptic drugs
    Dale C Hesdorffer
    Gertrude H Sergievsky Center and Department of Epidemiology, Columbia University, 630 West 168th Street, P and S Unit 16, New York, NY, USA
    CNS Drugs 27:113-9. 2013
  10. pmc Design and phenomenology of the FEBSTAT study
    Dale C Hesdorffer
    GH Sergievsky Center, Columbia University, 630 West 168th Street, P and S Unit 16, New York, NY 10032, USA
    Epilepsia 53:1471-80. 2012

Research Grants

Detail Information

Publications41

  1. doi request reprint Long-term psychiatric outcomes following traumatic brain injury: a review of the literature
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, and Department of Epidemiology, Mailman School of Public Health, New York, NY 10032, USA
    J Head Trauma Rehabil 24:452-9. 2009
    ..To determine the relationship between traumatic brain injury (TBI) and long-term psychiatric health outcomes, occurring 6 months or more after TBI...
  2. ncbi request reprint Are certain diuretics also anticonvulsants?
    D C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
    Ann Neurol 50:458-62. 2001
    ..Given the potential therapeutic value for seizure control, low toxicity, and low cost, therapeutic efficacy should be explored in clinical studies...
  3. ncbi request reprint Marked improvement in adherence to traumatic brain injury guidelines in United States trauma centers
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, New York, NY, USA
    J Trauma 63:841-7; discussion 847-8. 2007
    ..We conducted a survey of US trauma centers to evaluate guideline adherence, to examine predictors of adherence, and to compare our results with similar surveys conducted in 1991 and 2000...
  4. doi request reprint Status epilepticus without an underlying cause and risk of death: a population-based study
    Giancarlo Logroscino
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 10015, USA
    Arch Neurol 65:221-4. 2008
    ..To determine the independent effect of status epilepticus (SE) on risk of death...
  5. doi request reprint Estimating the incidence of first unprovoked seizure and newly diagnosed epilepsy in the low-income urban community of Northern Manhattan, New York City
    Emma K T Benn
    Gertrude H Sergievsky Center, Columbia University, New York, New York 10032, USA
    Epilepsia 49:1431-9. 2008
    ..To estimate the incidence and mortality associated with first unprovoked seizure or newly diagnosed epilepsy in a low-income, predominantly Hispanic community in Northern Manhattan, New York City...
  6. doi request reprint Suicidal ideation and behavior screening in intractable focal epilepsy eligible for drug trials
    Dale C Hesdorffer
    GH Sergievsky Center and Department of Epidemiology, Columbia University, New York, New York 10032, USA
    Epilepsia 54:879-87. 2013
    ..This was done to determine which instrument was optimal for use in epilepsy...
  7. doi request reprint Surveillance of epilepsy and prevention of epilepsy and its sequelae: lessons from the Institute of Medicine report
    Dale C Hesdorffer
    Department of Epidemiology, Gertrude H Sergievsky Center, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Curr Opin Neurol 26:168-73. 2013
    ..Evidence supporting these recommendations and the information that can be gained from them is reviewed...
  8. pmc Research implications of the Institute of Medicine Report, Epilepsy Across the Spectrum: Promoting Health and Understanding
    Dale C Hesdorffer
    GH Sergievksky Center, Columbia University, New York, New York 10024, USA
    Epilepsia 54:207-16. 2013
    ..The IOM report has many other research priorities for researchers to consider developing to advance the field of epilepsy and better the lives of people with epilepsy...
  9. doi request reprint Sudden unexpected death in epilepsy. Potential role of antiepileptic drugs
    Dale C Hesdorffer
    Gertrude H Sergievsky Center and Department of Epidemiology, Columbia University, 630 West 168th Street, P and S Unit 16, New York, NY, USA
    CNS Drugs 27:113-9. 2013
    ..For patients for whom seizure control is unattainable, supervision or monitoring may prevent SUDEP, though this has never been formally tested...
  10. pmc Design and phenomenology of the FEBSTAT study
    Dale C Hesdorffer
    GH Sergievsky Center, Columbia University, 630 West 168th Street, P and S Unit 16, New York, NY 10032, USA
    Epilepsia 53:1471-80. 2012
    ..We report on the baseline phenomenology of the final cohorts as well as detailed aims and methodology...
  11. doi request reprint Epilepsy, suicidality, and psychiatric disorders: a bidirectional association
    Dale C Hesdorffer
    Gertrude H Sergievsky Center and Department of Epidemiology, Columbia University, New York, NY 10032, USA
    Ann Neurol 72:184-91. 2012
    ..A study was undertaken to determine whether psychiatric disorders associated with suicide are more common in incident epilepsy than in matched controls without epilepsy, before and after epilepsy diagnosis...
  12. doi request reprint Do antiepileptic drugs or generalized tonic-clonic seizure frequency increase SUDEP risk? A combined analysis
    Dale C Hesdorffer
    Department of Epidemiology, GH Sergievsky Center, Columbia University, New York, New York 10032, USA
    Epilepsia 53:249-52. 2012
    ..The prior analysis, however, did not evaluate AEDs and GTCS frequency concurrently...
  13. pmc Familial clustering of epilepsy and behavioral disorders: evidence for a shared genetic basis
    Dale C Hesdorffer
    Department of Epidemiology, GH Sergievsky Center, Columbia University, New York, New York 10032, USA
    Epilepsia 53:301-7. 2012
    ..To examine whether family history of unprovoked seizures is associated with behavioral disorders in epilepsy probands, thereby supporting the hypothesis of shared underlying genetic susceptibility to these disorders...
  14. doi request reprint Combined analysis of risk factors for SUDEP
    Dale C Hesdorffer
    Columbia University, New York, New York, USA
    Epilepsia 52:1150-9. 2011
    ..To pool data from four published case-control studies of sudden unexpected death in epilepsy (SUDEP) with live controls, to increase the power to determine risk factors...
  15. doi request reprint Health, wealth, and culture as predominant factors in psychosocial morbidity
    Dale C Hesdorffer
    Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Epilepsy Behav 15:S36-40. 2009
    ..Their careful evaluation is vital to identifying people at greatest risk for depression in epilepsy and for informing interventions to prevent the occurrence of this disabling epilepsy comorbidity...
  16. doi request reprint Is a first acute symptomatic seizure epilepsy? Mortality and risk for recurrent seizure
    Dale C Hesdorffer
    Department of Epidemiology, The Gertrude H Sergievsky Center, Mailman School of Public Health at Columbia University, New York, New York 10032, USA
    Epilepsia 50:1102-8. 2009
    ..To compare mortality and subsequent unprovoked seizure risk in a population-based study of acute symptomatic seizure and first unprovoked seizure due to static brain lesions...
  17. pmc Estimating risk for developing epilepsy: a population-based study in Rochester, Minnesota
    D C Hesdorffer
    G H Sergievsky Center, 630 West 168th Street, P and S Unit 16, New York, NY 10032, USA
    Neurology 76:23-7. 2011
    ..We report the lifetime risk for epilepsy, accounting for the competing risk of mortality...
  18. ncbi request reprint Are MRI-detected brain abnormalities associated with febrile seizure type?
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, New York, NY 10032, USA
    Epilepsia 49:765-71. 2008
    ..We undertook a study to determine the frequency of MRI-detected brain abnormalities and to evaluate their association with FS type and with specific features of complex FS...
  19. doi request reprint The FDA alert on suicidality and antiepileptic drugs: Fire or false alarm?
    Dale C Hesdorffer
    Gertrude H Sergievsky Center and Department of Epidemiology, Columbia University, New York, NY 10032, USA
    Epilepsia 50:978-86. 2009
    ....
  20. ncbi request reprint Predictors of compliance with the evidence-based guidelines for traumatic brain injury care: a survey of United States trauma centers
    Dale C Hesdorffer
    GH Sergievsky Center, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
    J Trauma 52:1202-9. 2002
    ..In 1995, evidence-based guidelines for the management of severe traumatic brain injury (TBI) were published and disseminated. Information regarding their implementation is limited...
  21. ncbi request reprint Socioeconomic status is a risk factor for epilepsy in Icelandic adults but not in children
    Dale C Hesdorffer
    GH Sergievsky Center, Columbia Presbyterian Medical Center, New York, New York, USA
    Epilepsia 46:1297-303. 2005
    ..g., head injury, stroke) associated with low SES were not addressed in prior analyses. We assess the relation between SES indices and incident epilepsy separately for children and adults and in subgroups defined by seizure etiology...
  22. ncbi request reprint Depression and suicide attempt as risk factors for incident unprovoked seizures
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Ann Neurol 59:35-41. 2006
    ..These data suggest that depression and suicide attempt may be due to different underlying neurochemical pathways, each of which is important in the development of epilepsy...
  23. pmc Distribution of febrile seizure duration and associations with development
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, Departments of Epidemiology, Biostatistics, and Neurology, Columbia University, New York, NY 10032, USA
    Ann Neurol 70:93-100. 2011
    ..We assessed the distribution of FS duration in a cohort with first FSs, and the association between FS duration and baseline characteristics of the children...
  24. ncbi request reprint Mortality in the first 30 days following incident acute symptomatic seizures
    Dale C Hesdorffer
    GH Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, 10032, USA
    Epilepsia 46:43-5. 2005
    ..Very little is known about short-term mortality after acute symptomatic seizure. One study found an increased mortality in the first year after acute symptomatic seizure, like mortality following acute symptomatic status epilepticus...
  25. pmc Co-occurrence of major depression or suicide attempt with migraine with aura and risk for unprovoked seizure
    Dale C Hesdorffer
    The Gertrude H Sergievsky Center, Columbia University, 630 West 168th Street, P and S Unit 16, New York, NY 10032, USA
    Epilepsy Res 75:220-3. 2007
    ..This may reflect a new condition cluster defined by MA, MD, SA and unprovoked seizures. Identifying the biological underpinnings this cluster may affect clinical diagnosis and treatment...
  26. ncbi request reprint Recurrence of afebrile status epilepticus in a population-based study in Rochester, Minnesota
    D C Hesdorffer
    Gertrude H Sergievsky Center and Department of Neurology, Division of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Neurology 69:73-8. 2007
    ..To determine the risk of recurrence of status epilepticus (SE) in a population-based sample and to identify risk factors for recurrence...
  27. doi request reprint Underlying cause of death in incident unprovoked seizures in the urban community of Northern Manhattan, New York City
    Emma K T Benn
    Gertrude H Sergievsky Center, Columbia University, New York, New York 10032, USA
    Epilepsia 50:2296-300. 2009
    ..Older cases (> or =65 years) had increased SMRs for influenza and pneumonia. Underlying cause of death paralleled the underlying cause of seizure in patients with symptomatic etiologies...
  28. pmc Temporal trends in new exposure to antiepileptic drug monotherapy and suicide-related behavior
    Mary Jo V Pugh
    From the South Texas Veterans Health Care System VERDICT M J V P, C P W, J V T, E P F, San Antonio Department of Epidemiology and Biostatistics M J V P, C P W, University of Texas Health Science Center at San Antonio Department of Medicine M J V P, Texas A and M University, College Station Mailman School of Public Health D H, Sergievsky Center, The Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY Edith Nourse Rogers Memorial Hospital The Center for Health Quality, Outcomes and Economic Research CHQOER M E A, Bedford, MA Yale University School of Medicine J A C, New Haven, CT Epilepsy Therapy Project J A C, Houston, TX Rush University Medical Center A M K, Chicago, IL and National Center for Veterans Studies C J B, University of Utah, Salt Lake City
    Neurology 81:1900-6. 2013
    ....
  29. doi request reprint Associates of stigma in an incident epilepsy population from northern Manhattan, New York City
    Emily B Leaffer
    G H Sergievsky Center, Columbia University, New York, NY, USA
    Epilepsy Behav 21:60-4. 2011
    ..Stigma is associated with prevalent epilepsy, but its association with incident epilepsy is unknown...
  30. ncbi request reprint ADHD as a risk factor for incident unprovoked seizures and epilepsy in children
    Dale C Hesdorffer
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Arch Gen Psychiatry 61:731-6. 2004
    ..The association has been attributed to the epilepsy or its treatment, although it is impossible to determine in previous studies which condition occurs first...
  31. pmc Parental report of behavioral and cognitive diagnoses in childhood-onset epilepsy: A case-sibling-controlled analysis
    Emma K T Benn
    Gertrude H Sergievksy Center, Columbia University, New York, NY, USA
    Epilepsy Behav 18:276-9. 2010
    ..8, P<0.001), and had engaged in self-injurious behaviors other than suicide attempts (OR=5.5, P=0.013). Future research should examine whether these conditions first present during childhood influence prognosis into adulthood...
  32. ncbi request reprint Methodologic issues in studies of mortality following epilepsy: measures, types of studies, sources of cases, cohort effects, and competing risks
    Giancarlo Logroscino
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epilepsia 46:3-7. 2005
    ..Only this type of cohort permits a complete collection of data and the observation of the clinical phase of the disease from the diagnosis of epilepsy to the outcome of the study, death...
  33. doi request reprint Investigation of familial aggregation of seizures in neurocysticercosis patients
    Elizabeth A Kelvin
    HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University, 1051 Riverside Drive, Unit 15, New York, NY 10032, USA
    Epilepsy Res 84:67-71. 2009
    ..The results of our analyses were null, and there was no trend toward familial aggregation of seizures in NCC patients...
  34. ncbi request reprint Prevalence of self-reported epilepsy in a multiracial and multiethnic community in New York City
    Elizabeth A Kelvin
    G H Sergievsky Center, Columbia University, 622 West 168th Street, New York, NY 10032, USA
    Epilepsy Res 77:141-50. 2007
    ..To estimate the prevalence of epilepsy in a racially and ethnically diverse neighborhood in New York City...
  35. ncbi request reprint Risk of intracranial pathologic conditions requiring emergency intervention after a first complex febrile seizure episode among children
    David Teng
    Department of Pediatrics, Morgan Stanley Children s Hospital of New York Presbyterian, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Pediatrics 117:304-8. 2006
    ....
  36. ncbi request reprint Mortality after a first episode of status epilepticus in the United States and Europe
    Giancarlo Logroscino
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epilepsia 46:46-8. 2005
    ..The aim of this review is to summarize the available information on the epidemiology of SE and to outline the sources of the variability in reported mortality after SE...
  37. ncbi request reprint Outcome following decompressive craniectomy for malignant swelling due to severe head injury
    Bizhan Aarabi
    Department of Neurosurgery and R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Neurosurg 104:469-79. 2006
    ..The aim of this study was to assess outcome following decompressive craniectomy for malignant brain swelling due to closed traumatic brain injury (TBI)...
  38. ncbi request reprint White matter hyperintensities and their association with suicidality in depressed young adults
    Stefan Ehrlich
    Laboratory of Developmental Psychology and Developmental Psychopathology, McLean Hospital, Harvard Medical School, Boston, MA, USA
    J Affect Disord 86:281-7. 2005
    ....
  39. ncbi request reprint Epilepsy and suicide risk
    Dale C Hesdorffer
    Lancet Neurol 6:847; author reply 848. 2007
  40. ncbi request reprint Comment on epileptic seizures and epilepsy: definitions proposed by the International League Against Epilepsy (ILAE) and the International Bureau for Epilepsy (IBE)
    Ettore Beghi
    Epilepsia 46:1698-9; author reply 1701-2. 2005
  41. doi request reprint Phenomenology of prolonged febrile seizures: results of the FEBSTAT study
    S Shinnar
    Comprehensive Epilepsy Management Center, Montefiore Medical Center, Bronx, NY 10467, USA
    Neurology 71:170-6. 2008
    ..Febrile status epilepticus (FSE) has been associated with hippocampal injury and subsequent mesial temporal sclerosis and temporal lobe epilepsy. However, little is known about the semiology of FSE...

Research Grants5

  1. EPIDEMIOLOGY OF BRAIN ABNORMALITIES IN FEBRILE SEIZURES
    Dale Hesdorffer; Fiscal Year: 2002
    ..Answers to these questions may improve the clinical management of subgroups of children at risk for long-term disability so that future at-risk children can benefit from early interventions. ..