Haiying Hang

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1
    Haiying Hang
    Center for Radiological Research, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Genomics 79:487-92. 2002
  2. ncbi request reprint Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue
    Kevin M Hopkins
    Center for Radiological Research, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Cancer Res 63:5291-8. 2003
  3. pmc Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality
    Kevin M Hopkins
    Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Mol Cell Biol 24:7235-48. 2004
  4. ncbi request reprint Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways
    Shunchang Wang
    Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui 230031, People s Republic of China
    Toxicol Sci 102:345-51. 2008
  5. pmc Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways
    Zhigang Guo
    Department of Radiation Biology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA
    J Mol Biol 377:679-90. 2008
  6. doi request reprint Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development
    Zhishang Hu
    National Laboratory of Biomacromolecules, Chinese Academy of Sciences, Beijing, China
    Cancer Res 68:5552-61. 2008
  7. doi request reprint Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase
    Chunbo Zhang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Cell Physiol Biochem 22:295-306. 2008

Collaborators

  • Howard B Lieberman
  • R L Dunbrack
  • DEBRA WOLGEMUTH
  • Kevin M Hopkins
  • Chunbo Zhang
  • Shunchang Wang
  • Zhigang Guo
  • Zhishang Hu
  • Lu Han
  • Binghui Shen
  • Charles Xia Zhang
  • Muralidhar L Hegde
  • Leilei Yang
  • L David Finger
  • Yuheng Liu
  • Xiang Xiao
  • Minli Tang
  • Yun Zhao
  • Wei He
  • Xiao Yang
  • Jun Wang
  • Purnima Singh
  • Lijun Wu
  • Bei Pei
  • Yikun He
  • Valerie Chavez
  • M Prakash Hande
  • Wojtek Auerbach
  • Xiang Yuan Wang
  • Alexandra L Joyner
  • Ana Berlin
  • Xiaojian Wang
  • Harshwardhan M Thaker

Detail Information

Publications7

  1. ncbi request reprint Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1
    Haiying Hang
    Center for Radiological Research, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Genomics 79:487-92. 2002
    ..Furthermore, overexpression of HUS1B but not HUS1 in human cells induces clonogenic cell death. We suggest that HUS1B and HUS1 have distinct but related roles in regulating cell cycle checkpoints and genomic integrity...
  2. ncbi request reprint Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue
    Kevin M Hopkins
    Center for Radiological Research, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Cancer Res 63:5291-8. 2003
    ..The findings also indicate that HRAD9B can serve as a biomarker in particular for testicular seminomas and might be causally related to the disease...
  3. pmc Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality
    Kevin M Hopkins
    Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Mol Cell Biol 24:7235-48. 2004
    ..These investigations establish Mrad9 as a key mammalian genetic element of pathways that regulate the cellular response to DNA damage, maintenance of genomic integrity, and proper embryonic development...
  4. ncbi request reprint Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways
    Shunchang Wang
    Key Laboratory of Ion Beam Bioengineering, Institute of Plasma Physics, Chinese Academy of Sciences, Hefei, Anhui 230031, People s Republic of China
    Toxicol Sci 102:345-51. 2008
    ..Finally, our study demonstrates that C. elegans is a mammalian in vivo substitute model to study the mechanisms of Cd-induced apoptosis...
  5. pmc Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways
    Zhigang Guo
    Department of Radiation Biology, City of Hope National Medical Center and Beckman Research Institute, Duarte, CA 91010, USA
    J Mol Biol 377:679-90. 2008
    ..Replacement of one or more residues with an alanine in many cases leads to the complete loss of interaction, which may consequently lead to severe biological defects in mammals...
  6. doi request reprint Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development
    Zhishang Hu
    National Laboratory of Biomacromolecules, Chinese Academy of Sciences, Beijing, China
    Cancer Res 68:5552-61. 2008
    ..These data suggest that Mrad9 plays an important role in maintaining genomic stability and preventing tumor development in keratinocytes...
  7. doi request reprint Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase
    Chunbo Zhang
    National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
    Cell Physiol Biochem 22:295-306. 2008
    ..Taken together, these results suggest that phosphorylation of Rad9 plays a critical role in the activation of the S/M checkpoint, and that downstream proteins cdc2 and 14-3-3sigma mediate this function...