Research Topics
Species | CHRISTIAN GEORG HABECKSummaryAffiliation: Columbia University Country: USA Publications
Research Grants
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Detail Information
Publications
An event-related fMRI study of the neural networks underlying the encoding, maintenance, and retrieval phase in a delayed-match-to-sample taskChristian Habeck
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, 622 West 168th Street, PH 18, New York, NY 10032, USA
Brain Res Cogn Brain Res 23:207-20. 2005..The load-related activation patterns from encoding and retrieval phase and their relationship to behavior are also discussed...
Multivariate and univariate neuroimaging biomarkers of Alzheimer's diseaseChristian Habeck
Taub Institute, Columbia University Medical Center, New York, NY 10032, USA
Neuroimage 40:1503-15. 2008..Multivariate measures of AD utilize the covariance structure of imaging data and provide complementary, clinically relevant information that may be superior to univariate measures...- Relationship between baseline brain metabolism measured using [¹⁸F]FDG PET and memory and executive function in prodromal and early Alzheimer's diseaseChristian Habeck
Cognitive Neuroscience Division, The Taub Institute for Research on Aging and Alzheimer s Disease, Columbia University, New York, NY, USA
Brain Imaging Behav 6:568-83. 2012.... - Can the default-mode network be described with one spatial-covariance network?Christian Habeck
Cognitive Neuroscience Division, Taub Institute for Research on Aging and Alzheimer s Disease, Department of Neurology, Columbia University Medical Center, NY 10032, USA
Brain Res 1468:38-51. 2012..Our derived DMN network thus has potential for diagnostic applications that are simpler to perform than computation of pairwise correlational strengths or seed maps... - Contrasting visual working memory for verbal and non-verbal material with multivariate analysis of fMRIChristian Habeck
Cognitive Neuroscience Division, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, 630 West 168th Street, P and S 16, New York, NY 10032, USA
Brain Res 1467:27-41. 2012..Encoding processes, on the other hand, are critically dependent on the to-be-remembered material, and seem to necessitate material-specific neural substrates... 
Intrinsic functional-connectivity networks for diagnosis: just beautiful pictures?Christian Habeck
Department of Neurology, Taub Institute, Columbia University, New York, New York 10032, USA
Brain Connect 1:99-103. 2011..With the current commentary we also hope to benefit the field at large and contribute to a healthy debate about research goals and best practices...- An event-related fMRI study of the neural networks underlying repetition suppression and reaction time priming in implicit visual memoryChristian Habeck
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer s Disease and the Aging Brain, 622 West 168th Street, PH 18, New York, NY 10039, USA
Brain Res 1075:133-41. 2006..These results point to different neurophysiological processing mechanisms for structurally possible and impossible images and demonstrate neural plasticity that predicts behavioral priming for structurally possible images... - A new approach to spatial covariance modeling of functional brain imaging data: ordinal trend analysisChristian Habeck
Cognitive Neuroscience Division, Taub Institute, and Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Neural Comput 17:1602-45. 2005..In sum, OrT has potential applications to not only studies of young adults and their cognitive abilities, but also studies of normal aging and neurological and psychiatric disease... - Multivariate data analysis for neuroimaging data: overview and application to Alzheimer's diseaseChristian Habeck
Cognitive Neuroscience Division, The Taub Institute for Research on Aging and Alzheimer s Disease, Columbia University, New York, NY 10032, USA
Cell Biochem Biophys 58:53-67. 2010..Researchers should be able to employ them in an informed and accessible manner. The following article attempts to provide a basic introduction with sample applications to simulated and real-world data sets... - Relation of cognitive reserve and task performance to expression of regional covariance networks in an event-related fMRI study of nonverbal memoryChristian Habeck
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
Neuroimage 20:1723-33. 2003..e., there were reserve-related physiological differences that presumably would persist were there no subject differences in task performance. This suggests that this network may represent a neural correlate of CR... - Performance degradation and altered cerebral activation during dual performance: evidence for a bottom-up attentional systemYunglin Gazes
Cognitive Neuroscience Division, Taub Institute, Columbia University, New York, NY 10032, USA
Behav Brain Res 210:229-39. 2010..Furthermore, the ventral attention system, rather than the dorsal attention system, was found to mediate task coordination between tracking and visual detection... - Identification and differential vulnerability of a neural network in sleep deprivationSandra Bell-McGinty
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, 630 West 168th Street, PH-18, New York, USA
Cereb Cortex 14:496-502. 2004..A network whose expression decreased after sleep deprivation and correlated with memory performance was identified. We conclude that this activation network plays a role in cognitive function during sleep deprivation... - Altered PET functional brain responses in cognitively intact elderly persons at risk for Alzheimer disease (carriers of the epsilon4 allele)Nikolaos Scarmeas
Departments of Neurology, College of Physicians and Surgeons of Columbia University Medical Center 622 West 168th St, PH 19th floor New York, NY 10032, USA
Am J Geriatr Psychiatry 12:596-605. 2004..The authors investigated APOE-mediated differential brain activation in a group of healthy elderly subjects... - Brain networks associated with cognitive reserve in healthy young and old adultsYaakov Stern
Cognitive Neuroscience Division, Taub Institute, College of Physicians and Surgeons, Columbia University, New York, USA
Cereb Cortex 15:394-402. 2005..Thus, for the old subjects this topography may represent an altered, compensatory network that is used to maintain function in the face of age-related physiological changes... - A common neural network for cognitive reserve in verbal and object working memory in young but not oldYaakov Stern
Cognitive Neuroscience Division of the Taub Institute, NY, USA
Cereb Cortex 18:959-67. 2008..This spatial pattern could represent a general neural instantiation of CR that is affected by the aging process... - Reduction in cerebral blood flow in areas appearing as white matter hyperintensities on magnetic resonance imagingAdam M Brickman
Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, United States
Psychiatry Res 172:117-20. 2009..Regions with consistently lower CBF across individuals were more likely to appear as WMH. Results are consistent with an emerging literature linking diminished regional perfusion with the risk of developing WMH... - Separating function from structure in perfusion imaging of the aging brainIris Asllani
Program for Imaging and Cognitive Sciences in the Department of Radiology, Columbia University, New York, New York, USA
Hum Brain Mapp 30:2927-35. 2009.... - Structural MRI covariance patterns associated with normal aging and neuropsychological functioningAdam M Brickman
Cognitive Neuroscience Division, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 20032, USA
Neurobiol Aging 28:284-95. 2007..The results suggest that identifiable networks of grey and white matter regions systematically decline with age and that pattern expression is linked to age-related cognitive decline... - Imaging markers of mild cognitive impairment: multivariate analysis of CBF SPECTChaorui Huang
Center for Neurosciences, North Shore Long Island Jewish Health System, New York University School of Medicine, New York, NY, USA
Neurobiol Aging 28:1062-9. 2007..SPECT and neuropsychological testing can be used objectively for both baseline diagnosis and to monitor changes in brain function during very early AD... - A forward application of age associated gray and white matter networksAdam M Brickman
Cognitive Neuroscience Division, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Hum Brain Mapp 29:1139-46. 2008..405, P = 0.024). The findings suggest that the previously derived age-associated covariance pattern for gray matter is reliable and may provide information that is more functionally meaningful than chronological age... - Multivariate and univariate analysis of continuous arterial spin labeling perfusion MRI in Alzheimer's diseaseIris Asllani
Department of Radiology, Columbia University, New York, New York 10032, USA
J Cereb Blood Flow Metab 28:725-36. 2008..When tested on extensive split-half analysis to map out the replicability of both multivariate and univariate approaches, the expression of the pattern from multivariate analysis was superior to that of the univariate... - The response-signal method reveals age-related changes in object working memoryArjun Kumar
Division of Cognitive Neuroscience, Taub Institute, Columbia University, New York, NY 10032, USA
Psychol Aging 23:315-29. 2008..Results suggest that in working memory, aging impairs both the maximum capacity for discriminability and the rate of information accumulation, but not the temporal threshold for discriminability... - An event-related fMRI study of the neurobehavioral impact of sleep deprivation on performance of a delayed-match-to-sample taskChristian Habeck
Cognitive Neuroscience Division of the Taub Institute for Research in Alzheimer's Disease and the Aging Brain, 630 West 168th Street, PH-18, New York, NY 10032, USA
Brain Res Cogn Brain Res 18:306-21. 2004..Subject decreases in pattern expression were correlated with reductions in recognition accuracy (p<0.05), increased intra-individual variability in reaction time (p<0.005) and increased lapsing (p<0.005)... - Mapping brain function using a 30-day interval between baseline and activation: a novel arterial spin labeling fMRI approachAjna Borogovac
Department of Biomedical Engineering, Columbia University, New York, New York, USA
J Cereb Blood Flow Metab 30:1721-33. 2010..Taken together, these results indicate that CBFd measure could be better suited than net CBF to map long-term changes in brain function...
Research Grants
- Early AD Detection with ASL MRI & Covariance AnalysisChristian Habeck; Fiscal Year: 2007....
- Multivariate approaches to neuroimaging analysisChristian Habeck; Fiscal Year: 2007..Finally, we will provide a software analysis package that will integrate the most common features of multivariate approaches in a user-friendly manner. ..
- Multivariate approaches to neuroimaging analysisChristian Habeck; Fiscal Year: 2009..Finally, we will provide a software analysis package that will integrate the most common features of multivariate approaches in a user-friendly manner. ..
- Early AD Detection with ASL MRI & Covariance AnalysisCHRISTIAN GEORG HABECK; Fiscal Year: 2010....