J M Gorman

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint The human dimension: how the prefrontal cortex modulates the subcortical fear response
    Rachel Lisa Berkowitz
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, Brooklyn, NY, USA
    Rev Neurosci 18:191-207. 2007
  2. ncbi request reprint Neuroanatomical hypothesis of panic disorder, revised
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, USA
    Am J Psychiatry 157:493-505. 2000
  3. ncbi request reprint Treatment of generalized anxiety disorder
    Jack M Gorman
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    J Clin Psychiatry 63:17-23. 2002
  4. ncbi request reprint Merging the cognitive behavioral and psychopharmacological paradigms in comparative studies: controversies, issues, and some solutions
    J M Gorman
    College of Physicians and Surgeons, Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Psychopharmacol Bull 35:111-24. 2001
  5. ncbi request reprint New developments in the neurobiological basis of anxiety disorders
    Jack M Gorman
    Department of Psychiatry, Columbia University, New York, New York 10032, USA
    Psychopharmacol Bull 36:49-67. 2002
  6. ncbi request reprint Does the brain noradrenaline network mediate the effects of the CO2 challenge?
    J M Gorman
    College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Psychopharmacol 17:265-6; discussion 267-8. 2003
  7. ncbi request reprint Heart rate variability in depressive and anxiety disorders
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons, New York, NY, USA
    Am Heart J 140:77-83. 2000
  8. ncbi request reprint Noradrenergic approaches to antidepressant therapy
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Psychiatry 61:13-6. 2000
  9. ncbi request reprint Specificity of panic response to CO(2) inhalation in panic disorder: a comparison with major depression and premenstrual dysphoric disorder
    J M Kent
    Biological Studies Unit, New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Psychiatry 158:58-67. 2001
  10. ncbi request reprint Opposite links of positive and negative symptomatology with memory errors in schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Psychiatry Res 88:15-24. 1999

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint The human dimension: how the prefrontal cortex modulates the subcortical fear response
    Rachel Lisa Berkowitz
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, Brooklyn, NY, USA
    Rev Neurosci 18:191-207. 2007
    ..Studies of prefrontal cortical function in psychiatric illness should be a fruitful method for identifying effective treatment approaches...
  2. ncbi request reprint Neuroanatomical hypothesis of panic disorder, revised
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, USA
    Am J Psychiatry 157:493-505. 2000
    ..Here they revise that hypothesis to consider developments in the preclinical understanding of the neurobiology of fear and avoidance...
  3. ncbi request reprint Treatment of generalized anxiety disorder
    Jack M Gorman
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    J Clin Psychiatry 63:17-23. 2002
    ..At present, the use of psychosocial therapy and second-generation antidepressants, such as some selective serotonin reuptake inhibitors and venlafaxine, offer the best approach to attaining long-term benefit for patients with GAD...
  4. ncbi request reprint Merging the cognitive behavioral and psychopharmacological paradigms in comparative studies: controversies, issues, and some solutions
    J M Gorman
    College of Physicians and Surgeons, Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Psychopharmacol Bull 35:111-24. 2001
    ..Here we reviewed our own experience in designing and conducting a multicenter study comparing medication and cognitive behavioral therapy and their combination for the treatment of panic disorder...
  5. ncbi request reprint New developments in the neurobiological basis of anxiety disorders
    Jack M Gorman
    Department of Psychiatry, Columbia University, New York, New York 10032, USA
    Psychopharmacol Bull 36:49-67. 2002
    ....
  6. ncbi request reprint Does the brain noradrenaline network mediate the effects of the CO2 challenge?
    J M Gorman
    College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Psychopharmacol 17:265-6; discussion 267-8. 2003
  7. ncbi request reprint Heart rate variability in depressive and anxiety disorders
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons, New York, NY, USA
    Am Heart J 140:77-83. 2000
    ..Hence there is potential for the treatment of psychiatric disorders to affect positively the development and course of cardiovascular disease...
  8. ncbi request reprint Noradrenergic approaches to antidepressant therapy
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Clin Psychiatry 61:13-6. 2000
    ..Clinicians now have a range of antidepressants with variable neurotransmitter effects, different side effect profiles, and some interesting differences in functional utility in their armamentarium for treating depression...
  9. ncbi request reprint Specificity of panic response to CO(2) inhalation in panic disorder: a comparison with major depression and premenstrual dysphoric disorder
    J M Kent
    Biological Studies Unit, New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Psychiatry 158:58-67. 2001
    ....
  10. ncbi request reprint Opposite links of positive and negative symptomatology with memory errors in schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Psychiatry Res 88:15-24. 1999
    ..Fewer errors were specifically associated with more affective flattening, alogia and anhedonia, whereas avolition was entirely unrelated to them...
  11. ncbi request reprint Differential carbon dioxide sensitivity in childhood anxiety disorders and nonill comparison group
    D S Pine
    New York State Psychiatric Institute, Box 74, 1051 Riverside Dr, New York, NY 10032, USA
    Arch Gen Psychiatry 57:960-7. 2000
    ....
  12. ncbi request reprint Respiratory variability in panic disorder
    J M Martinez
    Department of Psychiatry, Columbia University, New York, New York 10032, USA
    Depress Anxiety 14:232-7. 2001
    ..Our data suggest that increased respiratory variability may be an important trait feature for some panic disorder patients and may make them more vulnerable to CO(2)-induced panic...
  13. ncbi request reprint Depression, psychomotor retardation, negative symptoms, and memory in schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Neuropsychiatry Neuropsychol Behav Neurol 13:177-83. 2000
    ..The purpose of this study was to examine the relations between depression, psychomotor retardation, and negative symptoms in schizophrenia as well as the specific contribution of each of these factors to memory impairment...
  14. ncbi request reprint Growth hormone response to clonidine in adversely reared young adult primates: relationship to serial cerebrospinal fluid corticotropin-releasing factor concentrations
    J D Coplan
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, 1051 Riverside Drive, Unit 14, New York, NY 10032, USA
    Psychiatry Res 95:93-102. 2000
    ..These data raise the possibility that a reduced GH response to clonidine may inversely reflect trait-like increases of central nervous system (CNS) CRF activity...
  15. ncbi request reprint Memory and schizophrenia: differential link of processing speed and selective attention with two levels of encoding
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute and Creedmoor Psychiatric Center, New York, NY, USA
    J Psychiatr Res 34:121-7. 2000
    ..Selective attention only contributed to the superficial encoding processes. Thus, slowing of processing speed in schizophrenia seems to be more crucial for memory performance, since it affects memory in a pervasive way...
  16. ncbi request reprint Relation of familial schizophrenia to negative symptoms but not to the deficit syndrome
    D Malaspina
    Schizophrenia Research Unit, Department of Clinical Psychobiology, New York State Psychiatric Institute, NY 10032, USA
    Am J Psychiatry 157:994-1003. 2000
    ..Although a family history of schizophrenia has been associated with negative symptoms, family history is inconsistently related to the presence of the deficit syndrome...
  17. ncbi request reprint Schizophrenia subgroups differing in dichotic listening laterality also differ in neurometabolism and symptomatology
    D Malaspina
    Department of Psychiatry, Columbia University, New York, USA
    J Neuropsychiatry Clin Neurosci 12:485-92. 2000
    ..In contrast, the prefrontal-medial temporal imbalance present in both patient groups may typify the schizophrenia syndrome...
  18. ncbi request reprint Does affective blunting in schizophrenia reflect affective deficit or neuromotor dysfunction?
    R H Dworkin
    Department of Anesthesiology, College of Physicians and Surgeons, Columbia University, New York, NY 10032 3784, USA
    Schizophr Res 20:301-6. 1996
    ..Because the interpretation of such measures is therefore ambiguous, measures of diminished affective experience may have greater validity in research on affective deficits in schizophrenia than measures of blunted affective expression...
  19. ncbi request reprint Management of treatment-refractory panic disorder
    S J Mathew
    Columbia University, College of Physicians and Surgeons, Department of Clinical Psychobiology, New York State Psychiatric Institute, Unit 84, 1051 Riverside Drive, New York, NY 10032, USA
    Psychopharmacol Bull 35:97-110. 2001
    ..The role of CBT in the medication refractory patient has been explored, with preliminary suggestions of efficacy...
  20. ncbi request reprint Hippocampal pathology in schizophrenia: magnetic resonance imaging and spectroscopy studies
    L S Kegeles
    Department of Psychiatry, Columbia University, New York, NY, USA
    Psychiatry Res 98:163-75. 2000
    ..The preliminary finding of a lateralized abnormality in Glx is consistent with postmortem findings of asymmetric neurochemical temporal lobe abnormalities in schizophrenia...
  21. ncbi request reprint Multicenter collaborative panic disorder severity scale
    M K Shear
    Department of Psychiatry, University of Pittsburgh, PA, USA
    Am J Psychiatry 154:1571-5. 1997
    ..To address the lack of a simple and standardized instrument to assess overall panic disorder severity, the authors developed a scale for the measurement of panic disorder severity...
  22. ncbi request reprint Positive symptomatology and source-monitoring failure in schizophrenia--an analysis of symptom-specific effects
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
    Psychiatry Res 95:119-31. 2000
    ..However, this finer-grained analysis revealed that the three of them were in fact associated with hallucinations and/or delusions. On the other hand, thought disorganisation appeared to be independent from these mechanisms...
  23. ncbi request reprint Carbon dioxide hypersensitivity, hyperventilation, and panic disorder
    L A Papp
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY
    Am J Psychiatry 150:1149-57. 1993
    ..Cognitive strategies through cognitive control of respiration may supplement and accentuate these interventions. CONCLUSIONS: Panic disorder may be due to an inherently unstable autonomic nervous system, coupled with cognitive distress...
  24. ncbi request reprint Physiological changes during carbon dioxide inhalation in patients with panic disorder, major depression, and premenstrual dysphoric disorder: evidence for a central fear mechanism
    J M Gorman
    Department of Psychiatry, Columbia University, 1051 Riverside Dr, Unit 32, New York, NY 10032, USA
    Arch Gen Psychiatry 58:125-31. 2001
    ..Several reasons have been proposed to explain CO(2) breathing effects in PD. We examined differences in respiratory response to CO(2) breathing in 4 groups to address these issues...
  25. ncbi request reprint Brain event-related potentials (ERPs) in schizophrenia during a word recognition memory task
    J Kayser
    Department of Biopsychology, New York State Psychiatric Institute, New York, NY 10032, USA
    Int J Psychophysiol 34:249-65. 1999
    ..These findings suggest that impaired word recognition in schizophrenia may arise from a left lateralized deficit at an early stage of processing, beginning at 200-300 ms after word onset...
  26. ncbi request reprint SPECT imaging of odor identification in schizophrenia
    D Malaspina
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    Psychiatry Res 82:53-61. 1998
    ..These regions may be unique to schizophrenia or have broader implications for olfactory memory retrieval...
  27. ncbi request reprint Efficacy of open-label nefazodone treatment in patients with panic disorder
    L A Papp
    Department of Clinical Psychobiology, New York State Psychiatric Institute, New York 10032, USA
    J Clin Psychopharmacol 20:544-6. 2000
    ..Although the response rate was lower than that found with most other antipanic medications, given its favorable side effect profile, nefazodone may be a good alternative for patients apprehensive about potential adverse drug reactions...
  28. ncbi request reprint Neurobiological mechanisms of social anxiety disorder
    S J Mathew
    New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Am J Psychiatry 158:1558-67. 2001
    ..The authors critically surveyed several preclinical and clinical neurobiological models of social anxiety disorder...
  29. ncbi request reprint Enhanced stress reactivity in paediatric anxiety disorders: implications for future cardiovascular health
    C Monk
    Department of Child and Adolescent Psychiatry, New York State Psychiatric Institute, NY 10032, USA
    Int J Neuropsychopharmacol 4:199-206. 2001
    ..As such, the current data suggest that the presence of an anxiety disorder may identify youth who exhibit autonomic profiles that place them at risk for cardiac disease...
  30. ncbi request reprint Cardiac autonomic control buffers blood pressure variability responses to challenge: a psychophysiologic model of coronary artery disease
    R P Sloan
    Columbia Presbyterian Medical Center, Department of Psychiatry, Columbia University, New York, New York 10032, USA
    Psychosom Med 61:58-68. 1999
    ..Together, these data suggest a coherent, testable psychophysiological model of CAD. In this article, we review these data and make recommendations for research to examine the model...
  31. ncbi request reprint Clinical and cognitive factors associated with verbal memory task performance in patients with schizophrenia
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, USA
    Am J Psychiatry 158:758-64. 2001
    ..They wished to determine the specific contribution of each of these factors to various types of memory impairment...
  32. ncbi request reprint An ideal trial to test differential onset of antidepressant effect
    A C Leon
    Department of Biostatistics in Psychiatry, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Clin Psychiatry 62:34-6; discussion 37-40. 2001
    ....
  33. ncbi request reprint Event-related brain potentials (ERPs) in schizophrenia for tonal and phonetic oddball tasks
    J Kayser
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Biol Psychiatry 49:832-47. 2001
    ..Task-independent reductions of negativities between 80 and 280 msec after stimulus onset suggest a deficit of automatic stimulus classification in schizophrenia, which may be partly compensated by later effortful processing...
  34. ncbi request reprint Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications
    W G Frankle
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, 10032, USA
    Psychopharmacology (Berl) 175:473-80. 2004
    ..To examine the D2 occupancy of two commonly used antipsychotic medications and relate this to the D2 occupancy by endogenous dopamine in schizophrenia...
  35. ncbi request reprint Variations in differential gene expression patterns across multiple brain regions in schizophrenia
    P Katsel
    Department of Psychiatry, The Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029 6575, USA
    Schizophr Res 77:241-52. 2005
    ....
  36. ncbi request reprint Generalized anxiety disorder
    J M Gorman
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    Clin Cornerstone 3:37-46. 2001
    ..While the treatment of GAD is relatively straightforward, the diagnosis can be difficult. Hence, careful attention to several key symptomatic presentations is important...
  37. ncbi request reprint Variable foraging demand rearing: sustained elevations in cisternal cerebrospinal fluid corticotropin-releasing factor concentrations in adult primates
    J D Coplan
    Department of Psychiatry, SUNY Health Science Center, Brooklyn, New York 11203, USA
    Biol Psychiatry 50:200-4. 2001
    ..CONCLUSIONS: Disturbances of maternal-infant attachment processes have an enduring impact on primate CRF function into young adulthood. The CRF elevations following unpredictable maternal foraging conditions appear traitlike in nature...
  38. ncbi request reprint Perceptual asymmetries in schizophrenia: subtype differences in left hemisphere dominance for dichotic fused words
    M S Friedman
    New York State Psychiatric Institute and College of Physicians and Surgeons, Columbia University, New York, USA
    Am J Psychiatry 158:1437-40. 2001
    ..Dichotic listening techniques have been used to study hemispheric dominance for language in schizophrenia. The authors' goal was to compare subjects with paranoid and undifferentiated subtypes of schizophrenia...
  39. ncbi request reprint Acute panic inventory symptoms during CO(2) inhalation and room-air hyperventilation among panic disorder patients and normal controls
    R R Goetz
    Department of Clinical Psychobiology, New York State Psychiatric Institute, New York, New York 10032, USA
    Depress Anxiety 14:123-36. 2001
    ..The results are discussed in the context of patient (having a diagnosis of PD) and panic effects (rated as panicking to a challenge)...
  40. ncbi request reprint Medications and verbal memory impairment in schizophrenia: the role of anticholinergic drugs
    G Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 34:369-74. 2004
    ..We wished to assess the effect of three types of medication on verbal memory impairments in schizophrenia...
  41. pmc Increased baseline occupancy of D2 receptors by dopamine in schizophrenia
    A Abi-Dargham
    Departments of Psychiatry and Radiology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 97:8104-9. 2000
    ..This finding provides direct evidence of increased stimulation of D(2) receptors by dopamine in schizophrenia, consistent with increased phasic activity of dopaminergic neurons...
  42. ncbi request reprint A.E. Bennett Research Award. Prenatal rubella, premorbid abnormalities, and adult schizophrenia
    A S Brown
    Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 49:473-86. 2001
    ..CONCLUSIONS: These findings link a known prenatal exposure, a deviant neurodevelopmental trajectory in childhood and adolescence, and SSP in adulthood within the same individuals...
  43. ncbi request reprint Event-related potentials in schizophrenia during tonal and phonetic oddball tasks: relations to diagnostic subtype, symptom features and verbal memory
    G E Bruder
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Biol Psychiatry 50:447-52. 2001
    ..The findings also confirm the relationship of P3 to total Brief Psychiatric Rating Scale score, negative symptoms, and verbal associative memory...
  44. ncbi request reprint Cognitive-behavioral therapy for management of anxiety and medication taper in older adults
    Ethan E Gorenstein
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Am J Geriatr Psychiatry 13:901-9. 2005
    ....
  45. ncbi request reprint Interferon-induced depression and cognitive impairment in hepatitis C virus patients: a 72 week prospective study
    Abraham Reichenberg
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    AIDS 19:S174-8. 2005
    ....
  46. ncbi request reprint Antidepressant adherence and suicide risk in depressed youth
    Jeffrey J Weiss
    Am J Psychiatry 162:1756-7. 2005
  47. ncbi request reprint Catechol-O-methyltransferase (COMT) genotypes and working memory: associations with differing cognitive operations
    Gerard E Bruder
    Department of Psychiatry, Columbia University, New York, USA
    Biol Psychiatry 58:901-7. 2005
    ..This report examines the relation of COMT genotypes to performance on a battery of working memory tests differing in the cognitive operations to be performed on the material...
  48. ncbi request reprint Prediction of panic response to a respiratory stimulant by reduced orbitofrontal cerebral blood flow in panic disorder
    Justine M Kent
    Department of Psychiatry, Unit 41, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Psychiatry 162:1379-81. 2005
    ..The aim of this study was to examine regional cerebral blood flow changes in response to anxiety/panic provocation in subjects with panic disorder and healthy comparison subjects...
  49. ncbi request reprint Physical, mental, and social catastrophic cognitions as prognostic factors in cognitive-behavioral and pharmacological treatments for panic disorder
    Thomas V Hicks
    Department of Psychology, University of Vermont, Burlington, VT, USA
    J Consult Clin Psychol 73:506-14. 2005
    ....
  50. ncbi request reprint Delusional wife: a case of diagnostic ambiguity and treatment challenge
    Benjamin L Ose
    Mount Sinai School of Medicine, NY, USA
    J Psychiatr Pract 11:205-11. 2005
  51. ncbi request reprint A model of verbal memory impairments in schizophrenia: two systems and their associations with underlying cognitive processes and clinical symptoms
    Gildas Brébion
    Schizophrenia Research Unit, New York State Psychiatric Institute, New York, NY, USA
    Psychol Med 35:133-42. 2005
    ..The results have been reported in previous papers. In this paper we show how all these data could be integrated into a consistent pattern of associations...
  52. ncbi request reprint Neuropsychological differences between late-onset and recurrent geriatric major depression
    Michael A Rapp
    Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Pl, Box 1230, New York, NY 10029, USA
    Am J Psychiatry 162:691-8. 2005
    ..The purpose of this study was to explore differences in neuropsychological function, symptoms, and cardiovascular comorbidity between patients with late-onset and recurrent geriatric major depression...
  53. ncbi request reprint Functional disorders and comorbidity
    Jack M Gorman
    CNS Spectr 10:857. 2005
  54. ncbi request reprint Contemporary issues in the field
    Jack M Gorman
    CNS Spectr 10:929. 2005
  55. ncbi request reprint Cost-efficacy of individual and combined treatments for panic disorder
    R Kathryn McHugh
    Department of Psychology, Center for Anxiety and Related Disorders, Boston University, Boston, MA 02215, USA
    J Clin Psychiatry 68:1038-44. 2007
    ..As psychosocial, pharmacologic, and combined treatments have all demonstrated efficacy in the treatment of panic disorder, cost-efficacy analysis provides an additional source of information to guide clinical decision making...
  56. ncbi request reprint Greater depression severity in elderly patients with memory complaints is associated with decreased left temporal-parietal dominance indicated by dynamic susceptibility contrast magnetic resonance imaging cerebral blood volume measures
    Helen H Kyomen
    Division on Aging, Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Geriatr Psychiatry 15:604-10. 2007
    ..To assess the relationships among depressive signs and symptoms and left versus right temporal-parietal cerebral blood volumes (CBVs) in elderly patients with a primary complaint of memory loss...
  57. pmc Correlations between Diffusion Tensor Imaging (DTI) and Magnetic Resonance Spectroscopy (1H MRS) in schizophrenic patients and normal controls
    Cheuk Y Tang
    Department of Radiology, Mount Sinai School of Medicine NY, NY 10029, USA
    BMC Psychiatry 7:25. 2007
    ..DTI is thus sensitive to demyelination and other structural abnormalities. DTI has also shown abnormalities in these regions...
  58. pmc Preliminary evidence for cognitive mediation during cognitive-behavioral therapy of panic disorder
    Stefan G Hofmann
    Department of Psychology, Boston University, Boston, MA 02215, USA
    J Consult Clin Psychol 75:374-9. 2007
    ..Multilevel moderated mediation analyses provided preliminary support for the notion that changes in panic-related cognitions mediate changes in panic severity only in treatments that include CBT...
  59. pmc The effect of doxapram on brain imaging in patients with panic disorder
    Amir Garakani
    Laboratory of Clinical Psychobiology, Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
    Eur Neuropsychopharmacol 17:672-86. 2007
    ..This suggests that panic disorder patients activate frontal inhibitory centers less than controls, a tendency that may lower the threshold for panic...
  60. ncbi request reprint Predictors and time course of response among panic disorder patients treated with cognitive-behavioral therapy
    Cindy J Aaronson
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 69:418-24. 2008
    ..We provided open CBT treatment to patients who subsequently participated in a maintenance treatment study. This article reports on predictors and trajectory of response in 381 participants who completed treatment at 4 sites...
  61. ncbi request reprint Novel treatment approaches for refractory anxiety disorders
    Mark H Pollack
    Harvard Medical School and Center for Anxiety and Traumatic Stress Related Disorders, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Depress Anxiety 25:467-76. 2008
    ..Progress in the development of new treatments has great promise, but will only succeed through a concerted research effort that systematically evaluates potential areas of importance and properly uses scarce resources...
  62. ncbi request reprint A 56-year-old male presenting with acute psychosis and acute change in mental status
    Tanveer Padder
    Mount Sinai School of Medicine
    J Psychiatr Pract 12:411-4. 2006
  63. pmc Psychiatric behavioral aspects of comanagement of hepatitis C virus and HIV
    Jeffrey J Weiss
    Department of Psychiatry, Mount Sinai School of Medicine, 1160 Fifth Avenue, Box 1228, New York, NY 10029, USA
    Curr HIV/AIDS Rep 3:176-81. 2006
    ..There is an urgent need for research into the psychiatric and behavioral predictors of HCV treatment adherence and virologic outcome, as well as into the optimal psychiatric management of the neuropsychiatric sequelae of HCV therapy...
  64. ncbi request reprint Adjuvant galantamine for cognitive dysfunction in a patient with bipolar disorder
    Vasco Videira Dias
    Autonomous University of Lisbon, Lisbon, Portugal
    J Psychiatr Pract 12:327-31. 2006
  65. ncbi request reprint Decreased choline and creatine concentrations in centrum semiovale in patients with generalized anxiety disorder: relationship to IQ and early trauma
    Jeremy D Coplan
    Department of Psychiatry, Division of Neuropsychopharmacology, State University of New York, Downstate Medical Center, Brooklyn, 11023, USA
    Psychiatry Res 147:27-39. 2006
    ..These conclusions are deemed preliminary due to small sample size, with further study of cerebral WM in anxiety disorders suggested...
  66. ncbi request reprint Low cerebrospinal fluid transthyretin levels in depression: correlations with suicidal ideation and low serotonin function
    Gregory M Sullivan
    Division of Neuroscience, Department of Psychiatry, Columbia University, NY 10032, USA
    Biol Psychiatry 60:500-6. 2006
    ..Transthyretin (TTR) is a thyroid hormone binding protein synthesized by choroid plexus and secreted into cerebrospinal fluid (CSF). We sought to replicate and extend our previous findings of lower CSF TTR in depression...
  67. ncbi request reprint Increased hippocampal plaques and tangles in patients with Alzheimer disease with a lifetime history of major depression
    Michael A Rapp
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    Arch Gen Psychiatry 63:161-7. 2006
    ..Although there is increasing evidence that major depression may interact with neuropathological processes in AD, there have been no studies of neuropathological changes in AD as a function of history of major depression...
  68. ncbi request reprint The role of executive functioning in CBT: a pilot study with anxious older adults
    Jan Mohlman
    Department of Psychology, Syracuse University, 430 Huntington Hall, Syracuse, NY 13244, USA
    Behav Res Ther 43:447-65. 2005
    ..However, some participants may show improvement on both mood and cognitive skills during treatment, which is discussed further...
  69. ncbi request reprint Facial expressiveness in patients with schizophrenia compared to depressed patients and nonpatient comparison subjects
    Fabien Tremeau
    Nathan Kline Institute, Orangeburg, New York 10962, USA
    Am J Psychiatry 162:92-101. 2005
    ..Our aim was to study and compare facial expressive behaviors related to affective deficits in patients with schizophrenia, depressed patients, and nonpatient comparison subjects...
  70. pmc Resting neural activity distinguishes subgroups of schizophrenia patients
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 56:931-7. 2004
    ..We previously demonstrated symptom and physiologic differences between familial and sporadic schizophrenia patients and hypothesized that the groups would show different resting regional cerebral blood flow (rCBF) patterns...
  71. ncbi request reprint Anxiety and substance use comorbidity among inpatients with schizophrenia
    Renee D Goodwin
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Unit 43, New York 10032, USA
    Schizophr Res 61:89-95. 2003
    ..To determine the association between lifetime anxiety symptoms and anxiety disorders and substance use disorders among patients with schizophrenia...
  72. ncbi request reprint Treating generalized anxiety disorder
    Jack M Gorman
    Department of Psychiatry, Mt Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 64:24-9. 2003
    ..Antidepressants like paroxetine and venlafaxine are not only effective antidepressants but also effective anxiolytics, thus implying their special ability to treat GAD and concurrent depression, even over the long-term...
  73. ncbi request reprint The effect of pharmacotherapist characteristics on treatment outcome in panic disorder
    Jack M Gorman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, New York 10029, USA
    Depress Anxiety 17:88-93. 2003
    ..Depression and Anxiety 17:88-93, 2003...
  74. ncbi request reprint Standard and enhanced cognitive-behavior therapy for late-life generalized anxiety disorder: two pilot investigations
    Jan Mohlman
    Columbia University Department of Psychiatry and New York State Psychiatric Institute, USA
    Am J Geriatr Psychiatry 11:24-32. 2003
    ..The studies described here are, to our knowledge, the first to test the efficacy of individual-format CBT administered in a mental health clinic for treatment of late-life GAD...
  75. ncbi request reprint Occupancy of brain serotonin transporters during treatment with paroxetine in patients with social phobia: a positron emission tomography study with 11C McN 5652
    Justine M Kent
    New York State Psychiatry Institute, New York, NY 10032, USA
    Psychopharmacology (Berl) 164:341-8. 2002
    ....
  76. ncbi request reprint Molecular targets in the treatment of anxiety
    Justine M Kent
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Biol Psychiatry 52:1008-30. 2002
    ....
  77. ncbi request reprint Psychopharmacologic treatment of generalized anxiety disorder and the risk of major depression
    Renee D Goodwin
    Department of Epidemiology and Psychiatry, Columbia Unversity College of Physicians and Surgeons, New York, NY 10032, USA
    Am J Psychiatry 159:1935-7. 2002
    ..The authors sought to determine the association between treatment for generalized anxiety disorder and the risk of major depression among adults in the community...
  78. ncbi request reprint Source monitoring impairments in schizophrenia: characterisation and associations with positive and negative symptomatology
    Gildas Brébion
    Department of Psychological Medicine, Institute of Psychiatry, 103 Denmark Hill, SE5 8AZ, London, UK
    Psychiatry Res 112:27-39. 2002
    ..Cognitive mechanisms leading to different types of source monitoring errors and possibly to the formation of positive symptoms are discussed...
  79. pmc Paternal age and risk of schizophrenia in adult offspring
    Alan S Brown
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, USA
    Am J Psychiatry 159:1528-33. 2002
    ..The study examined the relation between paternal age at the time of birth and risk of schizophrenia in the adult offspring...
  80. ncbi request reprint Distinguishing generalized anxiety disorder, panic disorder, and mixed anxiety states in older treatment-seeking adults
    Jan Mohlman
    Department of Psychiatry, New York State Psychiatric Institute, Columbia University, Box 14, 1051 Riverside Drive, New York, NY 10032, USA
    J Anxiety Disord 18:275-90. 2004
    ..Results indicate that distinguishing features of GAD and PD in older treatment-seeking adults may be fewer and slightly different from those of younger adults...
  81. ncbi request reprint Prefrontal dopamine D1 receptors and working memory in schizophrenia
    Anissa Abi-Dargham
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, New York 10032, USA
    J Neurosci 22:3708-19. 2002
    ..Increased D1 receptor availability observed in patients with schizophrenia might represent a compensatory (but ineffective) upregulation secondary to sustained deficiency in mesocortical DA function...
  82. ncbi request reprint Salivary cortisol concentrations before and after carbon-dioxide inhalations in children
    Jeremy D Coplan
    Department of Psychiatry, SUNY Downstate, Brooklyn, NY, USA
    Biol Psychiatry 51:326-33. 2002
    ..If confirmed, this would relate hypothalamic-pituitary adrenal axis activation in juveniles, as in adults, and response to a well-studied respiratory procedure...
  83. ncbi request reprint Global benefit-risk assessment of antidepressants: venlafaxine XR and fluoxetine
    Richard Entsuah
    Global Clinical Biostatistics, Wyeth Ayerst Research, 500 Arcola Road, Collegeville, PA 19426, USA
    J Psychiatr Res 36:111-8. 2002
    ..Quantifying efficacy and safety differences between drugs is difficult because rigorous statistical methods to assess benefit and risk simultaneously are lacking...
  84. ncbi request reprint New molecular targets for antianxiety interventions
    Jack M Gorman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
    J Clin Psychiatry 64:28-35. 2003
    ..Finally, the stimulation of neurotrophic factors, such as brain-derived neurotrophic factor, which appears to enhance neurogenesis, may also prove to have anxiolytic effects...
  85. ncbi request reprint Differential response to placebo among patients with social phobia, panic disorder, and obsessive-compulsive disorder
    Jonathan D Huppert
    Center for Treatment and Study of Anxiety, University of Pennsylvania School of Medicine, 6th Floor, 3535 Market St, Philadelphia, PA 19104, USA
    Am J Psychiatry 161:1485-7. 2004
    ..Placebo effects in treatment of three anxiety disorders were compared...
  86. ncbi request reprint Dorsolateral prefrontal cortical pathology in generalized anxiety disorder: a proton magnetic resonance spectroscopic imaging study
    Sanjay J Mathew
    Department of Biological Psychiatry, New York State Psychiatric Institute, Columbia Unversity, New York, NY 10032, USA
    Am J Psychiatry 161:1119-21. 2004
    ..The present study used proton magnetic resonance spectroscopy to assess concentrations of N-acetylaspartate, often considered a marker of neuronal viability, in generalized anxiety disorder patients...
  87. ncbi request reprint The effect of successful treatment on the emotional and physiological response to carbon dioxide inhalation in patients with panic disorder
    Jack M Gorman
    Department of Psychiatry and the Laboratory of Clinical Psychobiology, Mount Sinai School of Medicine, New York, NY 10029, USA
    Biol Psychiatry 56:862-7. 2004
    ....
  88. ncbi request reprint Elevated maternal interleukin-8 levels and risk of schizophrenia in adult offspring
    Alan S Brown
    New York State Psychiatric Institute, 1051 Riverside Dr, Unit 2, New York, NY 10032, USA
    Am J Psychiatry 161:889-95. 2004
    ....
  89. ncbi request reprint Potential noradrenergic targets for cognitive enhancement in schizophrenia
    Joseph I Friedman
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    CNS Spectr 9:350-5. 2004
    ....
  90. ncbi request reprint Verbal memory in schizophrenia: additional evidence of subtypes having different cognitive deficits
    Gerard E Bruder
    New York State Psychiatric Institute, and Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA USA
    Schizophr Res 68:137-47. 2004
    ..The findings add to growing evidence for the existence of a subgroup of schizophrenia having a specific verbal memory deficit that is not limited to working memory, but extends to learning and recall of verbal material...
  91. ncbi request reprint Effects of hyperventilation on heart rate and QT variability in panic disorder pre- and post-treatment
    Gregory M Sullivan
    Department of Psychiatry, Columbia College of Physicians and Surgeons, 1051 Riverside Drive, New York, NY 10032, USA
    Psychiatry Res 125:29-39. 2004
    ..Yet these results must be interpreted cautiously; they are preliminary, exploratory and observed in a very small sample without a healthy comparison group...
  92. ncbi request reprint A magnetic resonance spectroscopic imaging study of adult nonhuman primates exposed to early-life stressors
    Sanjay J Mathew
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Biol Psychiatry 54:727-35. 2003
    ..Long-term behavioral, immunologic, and neurochemical alterations have been found in primates exposed to adverse early rearing...
  93. ncbi request reprint Rodent doxapram model of panic: behavioral effects and c-Fos immunoreactivity in the amygdala
    Gregory M Sullivan
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Biol Psychiatry 53:863-70. 2003
    ..Doxapram is a respiratory stimulant that reliably evokes panic attacks in patients with panic disorder. We examined doxapram in four rodent models of anxiety and sought to identify brain regions involved in its behavioral effects...
  94. ncbi request reprint Citalopram-induced diplopia
    Karin Dorell
    Psychosomatics 46:91-3. 2005
  95. ncbi request reprint Diphenoxylate hydrochloride dependency
    Ali Firoozabadi
    Shiraz University of Medical Sciences, Shiraz, Iran
    J Psychiatr Pract 13:278-80. 2007
  96. ncbi request reprint Open-label trial of riluzole in generalized anxiety disorder
    Sanjay J Mathew
    Department of Biological Psychiatry, New York State Psychiatric Institute, USA
    Am J Psychiatry 162:2379-81. 2005
    ..There is a need to identify novel pharmacotherapies for anxiety disorders. The authors examined the safety and efficacy of riluzole, an antiglutamatergic agent, in adult outpatients with generalized anxiety disorder...
  97. ncbi request reprint Axons, cells, and depression: the nexus of neurology and psychiatry in multiple sclerosis
    Jack M Gorman
    CNS Spectr 10:349-50. 2005
  98. ncbi request reprint The selective serotonin reuptake inhibitor citalopram increases fear after acute treatment but reduces fear with chronic treatment: a comparison with tianeptine
    Nesha S Burghardt
    W M Keck Foundation Laboratory of Neurobiology, Center for Neural Science, New York University, New York, New York 10003, USA
    Biol Psychiatry 55:1171-8. 2004
    ..In this study, we used fear conditioning to begin to understand how acute and chronic SSRI treatment might differentially affect well-characterized fear circuits...
  99. pmc Odor identification, eye tracking and deficit syndrome schizophrenia
    Dolores Malaspina
    New York State Psychiatric Institute, Columbia University Department of Psychiatry, 1051 Riverside Drive, New York, NY 10032, USA
    Biol Psychiatry 51:809-15. 2002
    ..Deficit syndrome (DS) schizophrenia patients have smooth pursuit eye movement (SPEM) dysfunction. We examined if they also had smell identification deficits, since social affiliation is related to olfaction in other mammals...
  100. ncbi request reprint Mood disorders in the medically ill: scientific review and recommendations
    Dwight L Evans
    School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Biol Psychiatry 58:175-89. 2005
    ....
  101. ncbi request reprint National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders
    Dennis S Charney
    Division of Intramural Research Programs, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 59:262-70. 2002
    ..Research is needed on the ethical conduct of studies to limit risks of medication-free intervals and facilitate poststudy treatment. Patients must fully understand the risks and lack of individualized treatment involved in research...