A H Glassman

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Does treating post-myocardial infarction depression reduce medical mortality?
    Alexander H Glassman
    New York State Psychiatric Institute, Columbia University, NY 10032, USA
    Arch Gen Psychiatry 62:711-2. 2005
  2. ncbi request reprint Schizophrenia, antipsychotic drugs, and cardiovascular disease
    Alexander H Glassman
    Department of Clinical Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 66:5-10. 2005
  3. ncbi request reprint Onset of major depression associated with acute coronary syndromes: relationship of onset, major depressive disorder history, and episode severity to sertraline benefit
    Alexander H Glassman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Arch Gen Psychiatry 63:283-8. 2006
  4. pmc Depression and cardiovascular comorbidity
    Alexander H Glassman
    Columbia University, New York, NY, USA
    Dialogues Clin Neurosci 9:9-17. 2007
  5. ncbi request reprint Sertraline treatment of major depression in patients with acute MI or unstable angina
    Alexander H Glassman
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, 1051 Riverside Dr, Unit 116, New York, NY 10032, USA
    JAMA 288:701-9. 2002
  6. ncbi request reprint Heart rate variability in acute coronary syndrome patients with major depression: influence of sertraline and mood improvement
    Alexander H Glassman
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Arch Gen Psychiatry 64:1025-31. 2007
  7. ncbi request reprint Depression and nicotine: preclinical and clinical evidence for common mechanisms
    R P Laje
    Department of Psychiatry, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Curr Psychiatry Rep 3:470-4. 2001
  8. doi request reprint Depression and cardiovascular disease
    A Glassman
    Department of Psychiatry, Columbia University College of Physicians and 14 Surgeons, New York, USA
    Pharmacopsychiatry 41:221-5. 2008
  9. ncbi request reprint Smoking cessation and the course of major depression: a follow-up study
    A H Glassman
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, 1051 Riverside Drive, 10032, New York, NY, USA
    Lancet 357:1929-32. 2001
  10. doi request reprint Psychiatric characteristics associated with long-term mortality among 361 patients having an acute coronary syndrome and major depression: seven-year follow-up of SADHART participants
    Alexander H Glassman
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New Yourk, NY, USA
    Arch Gen Psychiatry 66:1022-9. 2009

Research Grants

  1. National Death Index Search for Participants in SADHART
    Alexander Glassman; Fiscal Year: 2005

Detail Information

Publications31

  1. ncbi request reprint Does treating post-myocardial infarction depression reduce medical mortality?
    Alexander H Glassman
    New York State Psychiatric Institute, Columbia University, NY 10032, USA
    Arch Gen Psychiatry 62:711-2. 2005
  2. ncbi request reprint Schizophrenia, antipsychotic drugs, and cardiovascular disease
    Alexander H Glassman
    Department of Clinical Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 66:5-10. 2005
    ..Thus, it is prudent for the psychiatric community to be aware of psychiatric patients' baseline medical condition and their risk status for cardiovascular disease...
  3. ncbi request reprint Onset of major depression associated with acute coronary syndromes: relationship of onset, major depressive disorder history, and episode severity to sertraline benefit
    Alexander H Glassman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Arch Gen Psychiatry 63:283-8. 2006
    ..No evidence of harm was seen, and sertraline hydrochloride had an overall beneficial effect on mood that occurred primarily in patients with a history of episodes of major depressive disorder (MDD)...
  4. pmc Depression and cardiovascular comorbidity
    Alexander H Glassman
    Columbia University, New York, NY, USA
    Dialogues Clin Neurosci 9:9-17. 2007
    ..There is strong evidence linking platelet activation, autonomic activity and inflammatory markers to both depression and heart disease, but why these links exist is far less clear...
  5. ncbi request reprint Sertraline treatment of major depression in patients with acute MI or unstable angina
    Alexander H Glassman
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, 1051 Riverside Dr, Unit 116, New York, NY 10032, USA
    JAMA 288:701-9. 2002
    ..However, no published evidence exists that antidepressant drugs are safe or efficacious in patients with unstable ischemic heart disease...
  6. ncbi request reprint Heart rate variability in acute coronary syndrome patients with major depression: influence of sertraline and mood improvement
    Alexander H Glassman
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Arch Gen Psychiatry 64:1025-31. 2007
    ..Although selective serotonin reuptake inhibitors may reduce mortality post-ACS, little is known about their effects on HRV...
  7. ncbi request reprint Depression and nicotine: preclinical and clinical evidence for common mechanisms
    R P Laje
    Department of Psychiatry, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Curr Psychiatry Rep 3:470-4. 2001
    ....
  8. doi request reprint Depression and cardiovascular disease
    A Glassman
    Department of Psychiatry, Columbia University College of Physicians and 14 Surgeons, New York, USA
    Pharmacopsychiatry 41:221-5. 2008
    ..However, that evidence is not definitive and the reason behind the association between depression and cardiovascular morbidity and mortality remains uncertain...
  9. ncbi request reprint Smoking cessation and the course of major depression: a follow-up study
    A H Glassman
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, 1051 Riverside Drive, 10032, New York, NY, USA
    Lancet 357:1929-32. 2001
    ..However, these studies confound effects of abstinence and history of depression. We aimed to assess whether there is an increased risk of depression and for how long that increase lasts...
  10. doi request reprint Psychiatric characteristics associated with long-term mortality among 361 patients having an acute coronary syndrome and major depression: seven-year follow-up of SADHART participants
    Alexander H Glassman
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New Yourk, NY, USA
    Arch Gen Psychiatry 66:1022-9. 2009
    ..We observed the participants of the Sertraline Antidepressant Heart Attack Randomized Trial (SADHART) to establish features of MDD associated with long-term mortality...
  11. ncbi request reprint Review of the cardiovascular effects of heterocyclic antidepressants
    A H Glassman
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, NY 10032
    J Clin Psychiatry 54:16-22. 1993
    ..They share this property with Type 1A antiarrhythmic compounds, and a variety of Type 1 antiarrhythmics have recently been shown to increase mortality in postmyocardial infarction patients.(ABSTRACT TRUNCATED AT 250 WORDS)..
  12. ncbi request reprint Smokers' response to combination bupropion, nicotine patch, and counseling treatment by race/ethnicity
    Lirio S Covey
    New York State Psychiatric Institute, New York City, New York, USA
    Ethn Dis 18:59-64. 2008
    ..Evidence on how to tailor nicotine dependence treatment to specific race/ethnic groups is limited. The present study investigated responses to established smoking cessation treatments among African American, Hispanic, and White adults...
  13. ncbi request reprint A randomized trial of bupropion and/or nicotine gum as maintenance treatment for preventing smoking relapse
    Lirio S Covey
    Smoking Cessation Program, New York State Psychiatric Institute, Columbia University Medical Center, New York, NY 10032, USA
    Addiction 102:1292-302. 2007
    ..To investigate the efficacy of maintenance treatment with bupropion and/or nicotine gum for reducing smoking relapse...
  14. ncbi request reprint Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute Working Group Report
    Karina W Davidson
    Department of Medicine, Columbia University College of Physicians and Surgeons, 622 W 168th St, PH9 Center, Room 941, New York, NY 10032, USA
    Psychosom Med 68:645-50. 2006
    ..The National Heart, Lung, and Blood Institute convened an interdisciplinary working group of experts to develop recommendations for the assessment and treatment of depression in patients with coronary heart disease (CHD)...
  15. ncbi request reprint Assessment and treatment of depression in patients with cardiovascular disease: National Heart, Lung, and Blood Institute working group report
    Karina W Davidson
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA, and Centre Hospitalier de l Universite de Montreal Research Center, Quebec, Canada
    Ann Behav Med 32:121-6. 2006
  16. doi request reprint The American Heart Association science advisory on depression and coronary heart disease: an exploration of the issues raised
    J Thomas Bigger
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Cleve Clin J Med 77:S12-9. 2010
    ..Referral to a practice with the knowledge and resources to manage depression promotes successful management of depressed patients with CHD...
  17. ncbi request reprint A randomized trial of sertraline as a cessation aid for smokers with a history of major depression
    Lirio S Covey
    New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Am J Psychiatry 159:1731-7. 2002
    ..Specifically, sertraline's efficacy for smoking abstinence and its effects on withdrawal symptoms were evaluated...
  18. ncbi request reprint Advances in non-nicotine pharmacotherapy for smoking cessation
    L S Covey
    New York State Psychiatric Institute, New York 10032, USA
    Drugs 59:17-31. 2000
    ..Thus, available evidence indicates that non-nicotine drug treatments offer a promising panoply of therapeutic strategies for the addicted smoker...
  19. ncbi request reprint Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death
    A H Glassman
    Department of Clinical Psychopharmacology, New York State Psychiatric Institute, New York 10032, USA
    Am J Psychiatry 158:1774-82. 2001
    ..The authors review the mechanisms and establish the risk of torsade de pointes and sudden death with antipsychotic drugs...
  20. ncbi request reprint Clinical management of cardiovascular risks during treatment with psychotropic drugs
    Alexander H Glassman
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    J Clin Psychiatry 63:12-7. 2002
    ..Screening for cardiac vulnerability at baseline, as well as at regular intervals during treatment if the patient has certain risk factors, is important when treating patients with psychotropic agents...
  21. ncbi request reprint Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action
    CHARLES P O'BRIEN
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3900 Chestnut Street, Philadelphia, PA 19104 6178, USA
    Biol Psychiatry 56:703-13. 2004
  22. ncbi request reprint Pharmacoeconomic analysis of sertraline treatment of depression in patients with unstable angina or a recent myocardial infarction
    CHRISTOPHER M O'CONNOR
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
    J Clin Psychiatry 66:346-52. 2005
    ....
  23. ncbi request reprint Assessing cardiovascular risks versus clinical benefits of atypical antipsychotic drug treatment
    Herbert Y Meltzer
    Department of Psychiatry and Pharmacology, Vanderbilt University Medical Center, Nashville, Tenn 37212, USA
    J Clin Psychiatry 63:25-9. 2002
    ..This article discusses both risks and benefits of antipsychotic treatment and presents a treatment algorithm to aid the clinician in choosing medications for the psychotic patient...
  24. ncbi request reprint Platelet/endothelial biomarkers in depressed patients treated with the selective serotonin reuptake inhibitor sertraline after acute coronary events: the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART) Platelet Substudy
    Victor L Serebruany
    Sinai Center for Thrombosis Research, Johns Hopkins University, Baltimore, MD 21215, USA
    Circulation 108:939-44. 2003
    ..Accordingly, we serially assessed the release of established platelet/endothelial biomarkers in patients treated with sertraline vs placebo in the Sertraline AntiDepressant Heart Attack Randomized Trial (SADHART)...
  25. ncbi request reprint Enhanced platelet/endothelial activation in depressed patients with acute coronary syndromes: evidence from recent clinical trials
    Victor L Serebruany
    Sinai Center for Thrombosis Research, Johns Hopkins University, Baltimore, Maryland 21215, USA
    Blood Coagul Fibrinolysis 14:563-7. 2003
    ..These findings may contribute to the unfavorable outcome associated with clinical depression in patients with ACS...
  26. ncbi request reprint Influence of depression and effect of treatment with sertraline on quality of life after hospitalization for acute coronary syndrome
    J Robert Swenson
    University of Ottawa Heart Institute and Department of Psychiatry, Ottawa, Ontario, Canada
    Am J Cardiol 92:1271-6. 2003
    ..Sertraline was associated with clinically meaningful improvement in multiple quality-of-life domains in patients with acute coronary syndrome and recurrent depression...
  27. ncbi request reprint Relationship between release of platelet/endothelial biomarkers and plasma levels of sertraline and N-desmethylsertraline in acute coronary syndrome patients receiving SSRI treatment for depression
    Victor L Serebruany
    HeartDrug Research Laboratories, Johns Hopkins University, 7600 Osler Dr, Suite 307, Towson, MD 21204, USA
    Am J Psychiatry 162:1165-70. 2005
    ....
  28. ncbi request reprint Antidepressants in coronary heart disease: SSRIs reduce depression, but do they save lives?
    Alexander H Glassman
    JAMA 297:411-2. 2007
  29. ncbi request reprint Where there is depression, there is inflammation... sometimes!
    Alexander H Glassman
    Biol Psychiatry 62:280-1. 2007
  30. ncbi request reprint Depression as a risk factor for post-MI mortality
    Robert M Carney
    J Am Coll Cardiol 44:472; author reply 473-4. 2004
  31. ncbi request reprint Mood disorders in the medically ill: scientific review and recommendations
    Dwight L Evans
    School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Biol Psychiatry 58:175-89. 2005
    ....

Research Grants1

  1. National Death Index Search for Participants in SADHART
    Alexander Glassman; Fiscal Year: 2005
    ..This additional information would identify patients at extremely high risk for death and in urgent need of treatment, and would aid in designing a definitive trial testing if treatment reduces mortality. ..