Maria-Felice Ghilardi

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Impaired movement control in Alzheimer's disease
    M F Ghilardi
    INB CNR, Milano Istituto Scientifico San Raffaele, Universita di Milano, Milan, Italy
    Neurosci Lett 260:45-8. 1999
  2. ncbi request reprint Patterns of regional brain activation associated with different forms of motor learning
    M Ghilardi
    Center for Neurobiology and Behavior, Center for Neurobiology and Behavior, NYS Psychiatric Institute, Columbia College of Physicians and Surgeons, PI Annex Room 819, 10032, New York, NY, USA
    Brain Res 871:127-45. 2000
  3. ncbi request reprint Visual feedback has differential effects on reaching movements in Parkinson's and Alzheimer's disease
    M F Ghilardi
    INB CNR, Istituto Scientifico San Raffaele, Universita di Milano, Milan, Italy
    Brain Res 876:112-23. 2000
  4. ncbi request reprint The differential effect of PD and normal aging on early explicit sequence learning
    Maria Felice Ghilardi
    Center for Neurobiology and Behavior, Columbia College of Physicians and Surgeons, New York, NY 10032, USA
    Neurology 60:1313-9. 2003
  5. ncbi request reprint Impaired sequence learning in carriers of the DYT1 dystonia mutation
    Maria Felice Ghilardi
    Center for Neurobiology and Behavior, Columbia College of Physicians and Surgeons, New York, NY 11030, USA
    Ann Neurol 54:102-9. 2003
  6. ncbi request reprint Differential cortical and subcortical activations in learning rotations and gains for reaching: a PET study
    John W Krakauer
    Department of Neurology and Department of Neurobiology and Behavior, Columbia University, New York 10032, USA
    J Neurophysiol 91:924-33. 2004
  7. doi request reprint Dopaminergic suppression of brain deactivation responses during sequence learning
    Miklos Argyelan
    Center for Neurosciences, The Feinstein Institute for Medical Research, North Shore University Hospital, Manhasset, New York 11030, USA
    J Neurosci 28:10687-95. 2008
  8. pmc Preclinical Huntington's disease: compensatory brain responses during learning
    Andrew Feigin
    Center for Neurosciences, Institute for Medical Research, North Shore Long Island Jewish Health System, 350 Community Drive, Manhasset, NY 11030, USA
    Ann Neurol 59:53-9. 2006

Research Grants

Detail Information

Publications8

  1. ncbi request reprint Impaired movement control in Alzheimer's disease
    M F Ghilardi
    INB CNR, Milano Istituto Scientifico San Raffaele, Universita di Milano, Milan, Italy
    Neurosci Lett 260:45-8. 1999
    ..Patients' paths showed discontinuous segments and prolonged movement time; movement inaccuracy, which increased without visual feedback, correlated significantly with scores of disease severity, working memory and attention...
  2. ncbi request reprint Patterns of regional brain activation associated with different forms of motor learning
    M Ghilardi
    Center for Neurobiology and Behavior, Center for Neurobiology and Behavior, NYS Psychiatric Institute, Columbia College of Physicians and Surgeons, PI Annex Room 819, 10032, New York, NY, USA
    Brain Res 871:127-45. 2000
    ..These tasks can be used to assess specific aspects of motor learning with imaging in health and disease...
  3. ncbi request reprint Visual feedback has differential effects on reaching movements in Parkinson's and Alzheimer's disease
    M F Ghilardi
    INB CNR, Istituto Scientifico San Raffaele, Universita di Milano, Milan, Italy
    Brain Res 876:112-23. 2000
    ..Parkinsonian patients showed higher reliance on feedback commands only with cursor feedback: this could be explained by their difficulty in engaging effectively automatic routines when distractors are present...
  4. ncbi request reprint The differential effect of PD and normal aging on early explicit sequence learning
    Maria Felice Ghilardi
    Center for Neurobiology and Behavior, Columbia College of Physicians and Surgeons, New York, NY 10032, USA
    Neurology 60:1313-9. 2003
    ..However, it is not known whether this defect is present during the earliest stages of the illness or whether it reflects specific limitations in dividing attention between cognitive and motor requirements...
  5. ncbi request reprint Impaired sequence learning in carriers of the DYT1 dystonia mutation
    Maria Felice Ghilardi
    Center for Neurobiology and Behavior, Columbia College of Physicians and Surgeons, New York, NY 11030, USA
    Ann Neurol 54:102-9. 2003
    ..Although localized increases in neural activity may enable normal movement execution in these subjects, this mechanism may not compensate for their defect in sequence learning...
  6. ncbi request reprint Differential cortical and subcortical activations in learning rotations and gains for reaching: a PET study
    John W Krakauer
    Department of Neurology and Department of Neurobiology and Behavior, Columbia University, New York 10032, USA
    J Neurophysiol 91:924-33. 2004
    ..In contrast, early gain adaptation involves only subcortical structures, which we suggest reflects a more automatic process of contextual recalibration of a scaling factor...
  7. doi request reprint Dopaminergic suppression of brain deactivation responses during sequence learning
    Miklos Argyelan
    Center for Neurosciences, The Feinstein Institute for Medical Research, North Shore University Hospital, Manhasset, New York 11030, USA
    J Neurosci 28:10687-95. 2008
    ..002) and with the val(158)met catechol-O-methyltransferase genotype. Our findings suggest that dopamine can influence prefrontal deactivation during learning, and that these changes are linked to baseline performance and genotype...
  8. pmc Preclinical Huntington's disease: compensatory brain responses during learning
    Andrew Feigin
    Center for Neurosciences, Institute for Medical Research, North Shore Long Island Jewish Health System, 350 Community Drive, Manhasset, NY 11030, USA
    Ann Neurol 59:53-9. 2006
    ..Nonetheless, this mechanism may not be sufficient to sustain a normal level of task performance, even during the presymptomatic stage of the disease...

Research Grants3

  1. Motor Learning in Parkinson's Disease
    M Ghilardi; Fiscal Year: 2002
    ....
  2. Consolidation of Motor Skills & Sleep Homeostasis in Parkinson's Disease
    M Ghilardi; Fiscal Year: 2007
    ..Consistent with the goals of NINDS, these studies will provide the basis for a rational therapeutic approach to enhancing sleep homeostasis in PD patients to improve their motor skills and quality of life. ..