Steven J Frucht

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Parkinson disease: an update
    Steven J Frucht
    Columbia Presbyterian Medical Center, New York, NY 10032, USA
    Neurologist 10:185-94. 2004
  2. pmc Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population
    Xinmin Liu
    Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    BMC Med Genet 12:104. 2011
  3. ncbi request reprint A pilot tolerability and efficacy study of levetiracetam in patients with chronic myoclonus
    S J Frucht
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Neurology 57:1112-4. 2001
  4. ncbi request reprint A pilot tolerability and efficacy trial of sodium oxybate in ethanol-responsive movement disorders
    Steven J Frucht
    Department of Neurology, Columbia University Medical Center, New York, New York 10032, USA
    Mov Disord 20:1330-7. 2005
  5. ncbi request reprint The metabolic topography of posthypoxic myoclonus
    Steven J Frucht
    Department of Neurology, Columbia Presbyterian Medical Center, New York, NY, USA
    Neurology 62:1879-81. 2004
  6. ncbi request reprint Movement disorder emergencies in the perioperative period
    Steven J Frucht
    Columbia Presbyterian Medical Center, Department of Neurology, 710 West 168th Street, New York, NY 10032, USA
    Neurol Clin 22:379-87. 2004
  7. ncbi request reprint Movement disorder emergencies
    Steven J Frucht
    Department of Neurology, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA
    Curr Neurol Neurosci Rep 5:284-93. 2005
  8. ncbi request reprint A single-blind, open-label trial of sodium oxybate for myoclonus and essential tremor
    S J Frucht
    Columbia University Medical Center, New York, USA
    Neurology 65:1967-9. 2005
  9. ncbi request reprint Marked amelioration of alcohol-responsive posthypoxic myoclonus by gamma-hydroxybutyric acid (Xyrem)
    Steven J Frucht
    Department of Neurology, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA
    Mov Disord 20:745-51. 2005
  10. ncbi request reprint Emergency treatment of movement disorders
    Shu Ching Hu
    Steven J Frucht, MD Department of Neurology, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA
    Curr Treat Options Neurol 9:103-14. 2007

Detail Information

Publications40

  1. ncbi request reprint Parkinson disease: an update
    Steven J Frucht
    Columbia Presbyterian Medical Center, New York, NY 10032, USA
    Neurologist 10:185-94. 2004
    ..For neurologists faced with the task of treating PD patients, the available array of medications may be confusing and intimidating...
  2. pmc Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population
    Xinmin Liu
    Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    BMC Med Genet 12:104. 2011
    ..Collectively the associations identified in these GWAS account for only a small proportion of the estimated total heritability of PD suggesting that an 'unknown' component of the genetic architecture of PD remains to be identified...
  3. ncbi request reprint A pilot tolerability and efficacy study of levetiracetam in patients with chronic myoclonus
    S J Frucht
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Neurology 57:1112-4. 2001
    ..Levetiracetam was well tolerated. Three of five patients with cortical myoclonus experienced reductions in their myoclonus scores, providing support for a larger, placebo-controlled trial in cortical myoclonus...
  4. ncbi request reprint A pilot tolerability and efficacy trial of sodium oxybate in ethanol-responsive movement disorders
    Steven J Frucht
    Department of Neurology, Columbia University Medical Center, New York, New York 10032, USA
    Mov Disord 20:1330-7. 2005
    ..Tolerability was satisfactory, with dose-dependent sedation as the most common side effect. Further studies of this drug in hyperkinetic movement disorders are warranted...
  5. ncbi request reprint The metabolic topography of posthypoxic myoclonus
    Steven J Frucht
    Department of Neurology, Columbia Presbyterian Medical Center, New York, NY, USA
    Neurology 62:1879-81. 2004
    ..Interventions such as deep brain stimulation that interrupt networks that involve these structures may be useful in patients with severe PHM...
  6. ncbi request reprint Movement disorder emergencies in the perioperative period
    Steven J Frucht
    Columbia Presbyterian Medical Center, Department of Neurology, 710 West 168th Street, New York, NY 10032, USA
    Neurol Clin 22:379-87. 2004
    ..By paying attention to the phenomenology of the movement disorder, the effects of medications administered in the operating room, and unusual sequelae of surgery, neurologists can have a positive impact on the outcome of these patients...
  7. ncbi request reprint Movement disorder emergencies
    Steven J Frucht
    Department of Neurology, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA
    Curr Neurol Neurosci Rep 5:284-93. 2005
    ..The text of this article has appeared in nearly the same form as the Academy syllabus accompanying our course. It is being presented here so that readers of the journal may review the material...
  8. ncbi request reprint A single-blind, open-label trial of sodium oxybate for myoclonus and essential tremor
    S J Frucht
    Columbia University Medical Center, New York, USA
    Neurology 65:1967-9. 2005
    ..Tolerability was acceptable, and more than half of the patients chose to continue treatment after the trial. Double-blind placebo-controlled studies in these disorders are warranted...
  9. ncbi request reprint Marked amelioration of alcohol-responsive posthypoxic myoclonus by gamma-hydroxybutyric acid (Xyrem)
    Steven J Frucht
    Department of Neurology, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA
    Mov Disord 20:745-51. 2005
    ..The possible mechanisms of action and potential uses of this agent in other alcohol-responsive movement disorders are discussed...
  10. ncbi request reprint Emergency treatment of movement disorders
    Shu Ching Hu
    Steven J Frucht, MD Department of Neurology, Columbia University Medical Center, 710 West 168th Street, New York, NY 10032, USA
    Curr Treat Options Neurol 9:103-14. 2007
    ..When focal hyperkinetic movements dominate the picture, botulinum toxin injection is a useful adjunct to medications...
  11. doi request reprint Focal task-specific dystonia of the musicians' hand--a practical approach for the clinician
    Steven J Frucht
    Columbia University Medical Center, Department of Neurology, The Neurological Institute, New York, NY 10032, USA
    J Hand Ther 22:136-42; quiz 143. 2009
    ..Effective treatments including sensory rehabilitation and botulinum toxin injection offer real hope for symptomatic relief and also afford scientists the opportunity to investigate sensorimotor networks in the normal and abnormal state...
  12. ncbi request reprint Visual hallucinations in PD
    Steven J Frucht
    Columbia Presbyterian Medical Center, Department of Neurology, 710 West 168th Street, New York, NY 10032, USA
    Neurology 59:1965. 2002
  13. ncbi request reprint Dystonia, athetosis, and epilepsia partialis continua in a patient with late-onset Rasmussen's encephalitis
    Steven Frucht
    Columbia Presbyterian Medical Center, The Neurological Institute, New York, New York 1032, USA
    Mov Disord 17:609-12. 2002
    ..Intravenous immunoglobulin improved both hyperkinetic movements and EPC, but benefit was transient. The clinical significance and implications of these findings are discussed...
  14. doi request reprint Embouchure dystonia--Portrait of a task-specific cranial dystonia
    Steven J Frucht
    The Neurological Institute, Columbia University Medical Center, New York, New York 10032, USA
    Mov Disord 24:1752-62. 2009
    ..Once present, symptoms of ED did not remit and often disrupted careers and livelihoods. Better treatments are urgently needed for this unusual disorder of oral motor control...
  15. ncbi request reprint The natural history of embouchure dystonia
    S J Frucht
    Columbia Presbyterian Medical Center, The Neurological Institute, New York, New York 10032, USA
    Mov Disord 16:899-906. 2001
    ..Dystonia not infrequently spread to other oral tasks, often producing significant disability. Effective treatments are needed for this challenging and unusual disorder...
  16. doi request reprint Cognitive and motor function in long-duration PARKIN-associated Parkinson disease
    Roy N Alcalay
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York2Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York
    JAMA Neurol 71:62-7. 2014
    ..Data on the long-term cognitive outcomes of patients with PARKIN-associated Parkinson disease (PD) are unknown but may be useful when counseling these patients...
  17. pmc Self-report of cognitive impairment and mini-mental state examination performance in PRKN, LRRK2, and GBA carriers with early onset Parkinson's disease
    Roy N Alcalay
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    J Clin Exp Neuropsychol 32:775-9. 2010
    ..GBA carriers reported more impairment, but MMSE performance did not differ among genetic groups. Detailed neuropsychological testing is required to explore the association between cognitive impairment and GBA mutations...
  18. doi request reprint Movement disorder emergencies
    Kathleen L Poston
    Dept of Neurology, Columbia University Medical Center, 710 West 168th Street, 10032, New York, NY, USA
    J Neurol 255:2-13. 2008
    ....
  19. ncbi request reprint Diagnosis and management of pergolide-induced fibrosis
    Pinky Agarwal
    Department of Neurology, Columbia Presbyterian Medical Center, Division of Movement Disorders, New York, New York, USA
    Mov Disord 19:699-704. 2004
    ..Based on our experience with these patients and a review of cases of pergolide-induced fibrosis in the English-language literature, we propose guidelines for the diagnosis and management of this rare complication...
  20. ncbi request reprint Classification conundrums in paroxysmal dyskinesias: a new subtype or variations on classic themes?
    Michael H Pourfar
    Department of Neurology, Columbia University Medical Center, New York, New York 10032, USA
    Mov Disord 20:1047-51. 2005
    ..We describe 4 cases that do not fit easily into the current classification scheme, compare them with four others recently described in the literature, and raise the question as to whether they constitute a new subtype...
  21. doi request reprint Supine head tremor: a clinical comparison of essential tremor and spasmodic torticollis patients
    Angus Agnew
    GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    J Neurol Neurosurg Psychiatry 83:179-81. 2012
    ..There is an anecdotal sense that head tremor in ET is positional rather than resting, a feature which could aid in the diagnosis, yet no published data exist...
  22. ncbi request reprint Ventriculoperitoneal shunting of idiopathic normal pressure hydrocephalus increases midbrain size: a potential mechanism for gait improvement
    J Mocco
    Department of Neurological Surgery, Columbia University, New York, New York 10032, USA
    Neurosurgery 59:847-50; discussion 850-1. 2006
    ..The current study was undertaken to determine the effect of ventriculoperitoneal shunt placement on midbrain dimensions in INPH patients...
  23. ncbi request reprint Treatment options for sleep dysfunction in Parkinson's disease
    Mary Ann Thenganatt
    Department of Neurology, College of Physicians and Surgeons, Columbia University, 710 West 168th Street, New York, NY, 10032, USA
    Curr Treat Options Neurol 13:473-87. 2011
    ..The goal of therapy is to restore quality nighttime sleep without excessive daytime sedation and to improve the patient's daily mental and physical function and overall quality of life...
  24. ncbi request reprint Myoclonus
    Victoria C Chang
    Victoria C Chang, MD Neurological Institute, Columbia University Medical Center, 710 West 168th Street, 3rd Floor, New York, NY 10032, USA
    Curr Treat Options Neurol 10:222-9. 2008
    ..Meanwhile, the clinical approach to diagnosing and classifying myoclonus remains largely unchanged. This review updates readers on current investigations and suggests guidelines for diagnosing and treating myoclonus...
  25. ncbi request reprint Prevalence of essential tremor in patients with Parkinson's disease vs. Parkinson-plus syndromes
    Elan D Louis
    Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Mov Disord 22:1402-7. 2007
    ..Patients with PD were three to thirteen times more likely to have diagnoses of ET than were patients with Parkinson-plus syndromes. These data further confirm the link between ET and PD, and possibly, between ET and Lewy body disease...
  26. ncbi request reprint The clinical challenge of posthypoxic myoclonus
    Steven J Frucht
    Department of Neurology, Columbia Presbyterian Medical Center, Neurological Institute, New York, New York, USA
    Adv Neurol 89:85-8. 2002
  27. ncbi request reprint Chemotherapy-induced parkinsonism responsive to levodopa: an underrecognized entity
    Cathy Chuang
    The Neurological Institute, Columbia Presbyterian Medical Center, New York, NY, USA
    Mov Disord 18:328-31. 2003
    ..All 3 patients responded dramatically to treatment with levodopa, and parkinsonism spontaneously improved or remitted over months. This unusual complication of cancer therapy is treatable and may be underappreciated...
  28. ncbi request reprint Focal task-specific dystonia in musicians
    Steven J Frucht
    Department of Neurology, Columbia University, New York, New York, USA
    Adv Neurol 94:225-30. 2004
  29. ncbi request reprint Severe cervical dystonia in pathologically proven Parkinson's disease and dementia
    Oren Cohen
    Department of Neurology, Columbia Presbyterian Medical Center, New York, New York, USA
    Mov Disord 18:1381-2. 2003
    ..The clinical diagnosis of Parkinson's disease and dementia (PDD) was confirmed at autopsy...
  30. doi request reprint The hand that has forgotten its cunning--lessons from musicians' hand dystonia
    Anna M Conti
    The Neurological Institute, Columbia University Medical Center, New York, New York, USA
    Mov Disord 23:1398-406. 2008
    ..The clinical implications of these findings and their possible relationship to the pathophysiology of focal task-specific dystonia are explored...
  31. ncbi request reprint Geste antagonistes in idiopathic lower cranial dystonia
    Steven E Lo
    The Neurological Institute, Columbia University Medical Center, New York, New York, USA
    Mov Disord 22:1012-7. 2007
    ..In most patients, dystonia was task-specific. Taking advantage of the improvement with a sensory geste, we manufactured oral appliances that mimicked the geste in 8 patients, and 3 continue to use it...
  32. pmc Motor phenotype of LRRK2 G2019S carriers in early-onset Parkinson disease
    Roy N Alcalay
    Department of Neurology, Columbia University, New York, NY 10032, USA
    Arch Neurol 66:1517-22. 2009
    ....
  33. doi request reprint The definition of dystonia: current concepts and controversies
    Steven J Frucht
    Department of Neurology, Mount Sinai Medical Center, New York, NY 10029, USA
    Mov Disord 28:884-8. 2013
    ..In this paper, a practical definition of dystonia for the movement disorders expert is presented, based on a new algorithm. © 2013 Movement Disorder Society. ..
  34. ncbi request reprint Myoclonus
    Pinky Agarwal
    Department of Neurology, Columbia Presbyterian Medical Center, New York, NY 10032, USA
    Curr Opin Neurol 16:515-21. 2003
    ..The sudden, shock-like jerks which define myoclonus may be highly disabling, and when they persist, often require treatment...
  35. pmc Identification and management of deep brain stimulation intra- and postoperative urgencies and emergencies
    Takashi Morishita
    Department of Neurology, University of Florida College of Medicine Shands Hospital, Movement Disorders Center, McKnight Brain Institute, Gainesville, FL 32610, USA
    Parkinsonism Relat Disord 16:153-62. 2010
    ..We have included ten illustrative (and actual) case vignettes to augment the discussion of each issue...
  36. ncbi request reprint Tetrabenazine therapy of pediatric hyperkinetic movement disorders
    Samay Jain
    Department of Neurology, Movement Disorders Division, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Mov Disord 21:1966-72. 2006
    ..When compared to adult patients, pediatric patients required higher doses. Side effects were similar to the adult population; however, children had a lower incidence of drug-induced Parkinsonism...
  37. ncbi request reprint Tetrabenazine in the treatment of severe pediatric chorea
    Anjan Chatterjee
    Department of Neurology, Columbia Presbyterian Medical Center, New York, New York, USA
    Mov Disord 18:703-6. 2003
    ..We report on 5 children with severe chorea who were treated with TBZ. TBZ effectively controlled chorea in 4 patients, and despite the need for relatively high doses, it was well tolerated...
  38. ncbi request reprint The Unified Myoclonus Rating Scale
    Steven J Frucht
    Department of Neurology, Columbia University, Columbia Presbyterian Medical Center, Neurological Institute, New York, New York, USA
    Adv Neurol 89:361-76. 2002
  39. ncbi request reprint Is focal task-specific dystonia limited to the hand and face?
    Steven E Lo
    The Neurological Institute, Columbia University Medical Center, New York, New York 10032, USA
    Mov Disord 22:1009-11. 2007
    ..Our patients appear to demonstrated that task-specificity in focal dystonia may not be limited to skilled, rehearsed actions and that FTSD may occur in an activity that is relatively autonomic...
  40. ncbi request reprint Subthalamic stimulation for Parkinson disease: determination of electrode location necessary for clinical efficacy
    Shearwood McClelland
    Department of Neurological Surgery and Neurology, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Neurosurg Focus 19:E12. 2005
    ..This study was performed to examine these issues...