Ilya J Finkelstein

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Supported lipid bilayers and DNA curtains for high-throughput single-molecule studies
    Ilya J Finkelstein
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Methods Mol Biol 745:447-61. 2011
  2. pmc Single-stranded DNA curtains for real-time single-molecule visualization of protein-nucleic acid interactions
    Bryan Gibb
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, United States
    Anal Chem 84:7607-12. 2012
  3. pmc The promoter-search mechanism of Escherichia coli RNA polymerase is dominated by three-dimensional diffusion
    Feng Wang
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, USA
    Nat Struct Mol Biol 20:174-81. 2013
  4. pmc Single-molecule imaging of DNA curtains reveals mechanisms of KOPS sequence targeting by the DNA translocase FtsK
    Ja Yil Lee
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 109:6531-6. 2012
  5. pmc Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase
    Ilya J Finkelstein
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA
    Nature 468:983-7. 2010
  6. pmc Single-Molecule Imaging of FtsK Translocation Reveals Mechanistic Features of Protein-Protein Collisions on DNA
    Ja Yil Lee
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Mol Cell 54:832-43. 2014
  7. pmc Single molecule studies of homologous recombination
    Ilya J Finkelstein
    Departments of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA
    Mol Biosyst 4:1094-104. 2008
  8. pmc XPD helicase speeds through a molecular traffic jam
    Ilya J Finkelstein
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Mol Cell 35:549-50. 2009

Collaborators

  • David J Sherratt
  • Ja Yil Lee
  • Eric C Greene
  • Feng Wang
  • Bryan Gibb
  • Lidia K Arciszewska
  • Jason Gorman
  • Sy Redding
  • David R Reichman
  • Estelle Crozat
  • Tim D Silverstein

Detail Information

Publications8

  1. pmc Supported lipid bilayers and DNA curtains for high-throughput single-molecule studies
    Ilya J Finkelstein
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Methods Mol Biol 745:447-61. 2011
    ..In this protocol, we describe a novel, high-throughput, nanofabricated experimental platform enabling real-time imaging of hundreds of individual protein-DNA complexes over hour timescales...
  2. pmc Single-stranded DNA curtains for real-time single-molecule visualization of protein-nucleic acid interactions
    Bryan Gibb
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, United States
    Anal Chem 84:7607-12. 2012
    ..This new single-molecule approach provides long-awaited access to critical biological reactions involving single-stranded DNA binding proteins...
  3. pmc The promoter-search mechanism of Escherichia coli RNA polymerase is dominated by three-dimensional diffusion
    Feng Wang
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York, USA
    Nat Struct Mol Biol 20:174-81. 2013
    ....
  4. pmc Single-molecule imaging of DNA curtains reveals mechanisms of KOPS sequence targeting by the DNA translocase FtsK
    Ja Yil Lee
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 109:6531-6. 2012
    ....
  5. pmc Single-molecule imaging reveals mechanisms of protein disruption by a DNA translocase
    Ilya J Finkelstein
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA
    Nature 468:983-7. 2010
    ....
  6. pmc Single-Molecule Imaging of FtsK Translocation Reveals Mechanistic Features of Protein-Protein Collisions on DNA
    Ja Yil Lee
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Mol Cell 54:832-43. 2014
    ....
  7. pmc Single molecule studies of homologous recombination
    Ilya J Finkelstein
    Departments of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street, New York, NY 10032, USA
    Mol Biosyst 4:1094-104. 2008
    ..In this review, we present an overview of single molecule assays that have been developed to study key aspects of homologous recombination and discuss the unique information gleaned from these experiments...
  8. pmc XPD helicase speeds through a molecular traffic jam
    Ilya J Finkelstein
    Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA
    Mol Cell 35:549-50. 2009
    ..In this issue, Honda et al. (2009) report that the archaeal XPD helicase can bypass a single-stranded DNA-binding protein without either molecule being ejected from the DNA...