MICHEL J FERIN

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Endocrine and metabolic responses to long-term monotherapy with the antiepileptic drug valproate in the normally cycling rhesus monkey
    Michel Ferin
    Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:2908-15. 2003
  2. ncbi request reprint Elevated free IGF-I levels in prepubertal Hispanic girls with premature adrenarche: relationship with hyperandrogenism and insulin sensitivity
    Miriam E Silfen
    Division of Pediatric Endocrinology, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 87:398-403. 2002
  3. ncbi request reprint Müllerian inhibiting substance is an accurate marker of ovarian response in women of advanced reproductive age undergoing IVF
    Gary S Nakhuda
    Columbia University College of Physicians and Surgeons, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, New York, NY 10025, USA
    Reprod Biomed Online 14:450-4. 2007
  4. ncbi request reprint Bioavailable estradiol and age at onset of Alzheimer's disease in postmenopausal women with Down syndrome
    Nicole Schupf
    The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
    Neurosci Lett 406:298-302. 2006
  5. ncbi request reprint Early endocrine, metabolic, and sonographic characteristics of polycystic ovary syndrome (PCOS): comparison between nonobese and obese adolescents
    Miriam E Silfen
    Department of Pediatrics, Division of Pediatric Endocrinology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:4682-8. 2003
  6. ncbi request reprint Onset of dementia is associated with age at menopause in women with Down's syndrome
    Nicole Schupf
    The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
    Ann Neurol 54:433-8. 2003
  7. ncbi request reprint Predictors of ovulatory failure in women with epilepsy
    Martha J Morrell
    The Neurological Institute, Department of Neurology, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    Ann Neurol 52:704-11. 2002
  8. ncbi request reprint Decrease in luteinizing hormone pulse frequency during a five-hour peripheral ghrelin infusion in the ovariectomized rhesus monkey
    Nicolas R Vulliémoz
    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    J Clin Endocrinol Metab 89:5718-23. 2004
  9. ncbi request reprint Agouti-related protein stimulates the hypothalamic-pituitary-adrenal (HPA) axis and enhances the HPA response to interleukin-1 in the primate
    Ennian Xiao
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Endocrinology 144:1736-41. 2003
  10. ncbi request reprint Insulin sensitivity and the insulin-like growth factor system in prepubertal boys with premature adrenarche
    Michelle R Denburg
    Department of Pediatrics, Division of Pediatric Endocrinology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 87:5604-9. 2002

Research Grants

  1. Energy-Related Peptides and Reproductive Axis
    Michel Ferin; Fiscal Year: 2007
  2. ADRENAL AXIS AND THE REPRODUCTIVE PROCESS
    Michel Ferin; Fiscal Year: 2004
  3. ADRENAL AXIS AND THE REPRODUCTIVE PROCESS
    Michel Ferin; Fiscal Year: 2000

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Endocrine and metabolic responses to long-term monotherapy with the antiepileptic drug valproate in the normally cycling rhesus monkey
    Michel Ferin
    Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:2908-15. 2003
    ....
  2. ncbi request reprint Elevated free IGF-I levels in prepubertal Hispanic girls with premature adrenarche: relationship with hyperandrogenism and insulin sensitivity
    Miriam E Silfen
    Division of Pediatric Endocrinology, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 87:398-403. 2002
    ..These results suggest altered regulation of the insulin/IGF system in prepubertal girls with PA and a possible role for free IGF-I in the pathogenesis of the hyperandrogenism of PA as well as its progression to PCOS...
  3. ncbi request reprint Müllerian inhibiting substance is an accurate marker of ovarian response in women of advanced reproductive age undergoing IVF
    Gary S Nakhuda
    Columbia University College of Physicians and Surgeons, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, New York, NY 10025, USA
    Reprod Biomed Online 14:450-4. 2007
    ....
  4. ncbi request reprint Bioavailable estradiol and age at onset of Alzheimer's disease in postmenopausal women with Down syndrome
    Nicole Schupf
    The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY 10032, USA
    Neurosci Lett 406:298-302. 2006
    ..Our findings support the hypothesis that reductions in estrogen following menopause can contribute to the cascade of pathological processes leading to AD...
  5. ncbi request reprint Early endocrine, metabolic, and sonographic characteristics of polycystic ovary syndrome (PCOS): comparison between nonobese and obese adolescents
    Miriam E Silfen
    Department of Pediatrics, Division of Pediatric Endocrinology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:4682-8. 2003
    ..Our data also suggest differences in the IGF system between nonobese and obese adolescents with PCOS...
  6. ncbi request reprint Onset of dementia is associated with age at menopause in women with Down's syndrome
    Nicole Schupf
    The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
    Ann Neurol 54:433-8. 2003
    ..Our findings support the hypothesis that reductions in estrogens after menopause contribute to the cascade of pathological processes leading to AD...
  7. ncbi request reprint Predictors of ovulatory failure in women with epilepsy
    Martha J Morrell
    The Neurological Institute, Department of Neurology, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    Ann Neurol 52:704-11. 2002
    ..WWE with anovulatory cycles may have no other signs of reproductive dysfunction. Therefore, clinicians must be alert to this potential complication of epilepsy...
  8. ncbi request reprint Decrease in luteinizing hormone pulse frequency during a five-hour peripheral ghrelin infusion in the ovariectomized rhesus monkey
    Nicolas R Vulliémoz
    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    J Clin Endocrinol Metab 89:5718-23. 2004
    ..Ghrelin also activates the adrenal axis, but the relevance of this to the inhibition of GnRH pulse frequency remains to be established...
  9. ncbi request reprint Agouti-related protein stimulates the hypothalamic-pituitary-adrenal (HPA) axis and enhances the HPA response to interleukin-1 in the primate
    Ennian Xiao
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Endocrinology 144:1736-41. 2003
    ..These studies suggest that, in addition to its known orexigenic effects, AGRP may play a role in neuroendocrine regulation and specifically that AGRP may interact with alpha-MSH to modulate neuroendocrine responses to inflammation...
  10. ncbi request reprint Insulin sensitivity and the insulin-like growth factor system in prepubertal boys with premature adrenarche
    Michelle R Denburg
    Department of Pediatrics, Division of Pediatric Endocrinology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 87:5604-9. 2002
    ..These findings suggest that both boys and girls with PA should be monitored for the development of insulin resistance and associated complications, including diabetes mellitus and cardiovascular disease...
  11. pmc Astressin B, a nonselective corticotropin-releasing hormone receptor antagonist, prevents the inhibitory effect of ghrelin on luteinizing hormone pulse frequency in the ovariectomized rhesus monkey
    Nicolas R Vulliémoz
    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, New York 10032, USA
    Endocrinology 149:869-74. 2008
    ....
  12. ncbi request reprint Administration of antivascular endothelial growth factor receptor 2 antibody in the early follicular phase delays follicular selection and development in the rhesus monkey
    Ralf C Zimmermann
    Department of Obstetrics and Gynecology and Center for Reproductive Sciences, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Endocrinology 143:2496-502. 2002
    ..The data clearly indicate that the recruitment-selection process of follicles in the early follicular phase in the nonhuman primate is controlled by VEGF, through the VEGF-R2...
  13. ncbi request reprint Pharmacokinetics and pharmacodynamics of single-chain recombinant human follicle-stimulating hormone containing the human chorionic gonadotropin carboxyterminal peptide in the rhesus monkey
    Jeffrey Klein
    Department of Obstetrics and Gynecology, Columbia University, College of Physicians and Surgeons, New York 10032, USA
    Fertil Steril 77:1248-55. 2002
    ....
  14. ncbi request reprint Melanocortin modulation of inflammatory cytokine and neuroendocrine responses to endotoxin in the monkey
    Nicolas R Vulliémoz
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Endocrinology 147:1878-83. 2006
    ..Moreover, they show for the first time that SHU9119, a mixed MC3/4-R antagonist, can decrease the IL-10 response, establishing a physiological role for endogenous MSH in modulating the release of an antiinflammatory cytokine...
  15. ncbi request reprint Astressin B, a corticotropin-releasing hormone receptor antagonist, accelerates the return to normal luteal function after an inflammatory-like stress challenge in the rhesus monkey
    Ennian Xiao
    Department of Obstetrics and Gynecology, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, New York, New York 10032, USA
    Endocrinology 148:841-8. 2007
    ..Systemic administration of astressin B accelerates the return to normal luteal function, presumably by restoring normal neuroendocrine regulation of gonadotropin secretion...
  16. ncbi request reprint Endotoxin stimulates leptin in the human and nonhuman primate
    Rita E Landman
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Clin Endocrinol Metab 88:1285-91. 2003
    ..The significance of these findings and the potential role of leptin in modulating the response to inflammation in the human require further study...
  17. pmc Effects of estradiol on cerebrospinal fluid levels of agouti-related protein in ovariectomized rhesus monkeys
    Ennian Xiao
    Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, New York 10032, USA
    Endocrinology 151:1002-9. 2010
    ..Furthermore, obesity was associated with resistance to the suppressive effects of E2 on AgRP, analogous to what is seen with obesity and leptin resistance...
  18. ncbi request reprint Central infusion of agouti-related peptide suppresses pulsatile luteinizing hormone release in the ovariectomized rhesus monkey
    Nicolas R Vulliémoz
    Department of Obstetrics and Gynecology, College of Physicians and Surgeons, 630 West 168th Street, New York, New York 10032, USA
    Endocrinology 146:784-9. 2005
    ....
  19. ncbi request reprint Inadequate luteal function is the initial clinical cyclic defect in a 12-day stress model that includes a psychogenic component in the Rhesus monkey
    Ennian Xiao
    Department of Obstetrics and Gynecology and Center for Reproductive Sciences, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Endocrinol Metab 87:2232-7. 2002
    ..Significant decreases in integrated luteal LH values in the poststress cycle suggest that these effects may be related to continuing disturbances in the neuroendocrine component of the reproductive axis...
  20. ncbi request reprint Leptin modulates inflammatory cytokine and neuroendocrine responses to endotoxin in the primate
    Ennian Xiao
    Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Endocrinology 144:4350-3. 2003
    ....

Research Grants15

  1. Energy-Related Peptides and Reproductive Axis
    Michel Ferin; Fiscal Year: 2007
    ..Overall, our data will provide novel information in support of a role of new orexigenic peptides in nutrition-related and perhaps also psychogenic stress-related reproductive dysfunction and infertility. ..
  2. ADRENAL AXIS AND THE REPRODUCTIVE PROCESS
    Michel Ferin; Fiscal Year: 2004
    ..abstract_text> ..
  3. ADRENAL AXIS AND THE REPRODUCTIVE PROCESS
    Michel Ferin; Fiscal Year: 2000
    ..Overall, the data will provide information about novel mechanisms by which HPA and stress influence themenstrual cycle and may suggest new therapeutical approaches to the problem of hypothalamic amenorrhea. ..