Mitchell Elkind

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Duration of diabetes and risk of ischemic stroke: the Northern Manhattan Study
    Chirantan Banerjee
    Department of Epidemiology, Columbia University, New York, NY, USA
    Stroke 43:1212-7. 2012
  2. ncbi Endothelial dysfunction is associated with carotid plaque: a cross-sectional study from the population based Northern Manhattan Study
    Tatjana Rundek
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, USA
    BMC Cardiovasc Disord 6:35. 2006
  3. ncbi Moderate alcohol consumption is associated with better endothelial function: a cross sectional study
    Keiko Suzuki
    Division of Cardiology, Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY, USA
    BMC Cardiovasc Disord 9:8. 2009
  4. ncbi Lipids and carotid plaque in the Northern Manhattan Study (NOMAS)
    Hannah Gardener
    Department of Neurology, Miller School of Medicine, University of Miami, FL, USA
    BMC Cardiovasc Disord 9:55. 2009
  5. ncbi Statins as acute-stroke treatment
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Int J Stroke 1:224-5. 2006
  6. ncbi High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, and Divisions of Biostatistics, Joseph P Mailman School of Public Health, Columbia University, New York, New York, USA
    Arch Intern Med 166:2073-80. 2006
  7. ncbi Infectious burden and carotid plaque thickness: the northern Manhattan study
    Mitchell S V Elkind
    Neurological Institute, 710 West 168th Street, Box 182, New York, NY 10032, USA
    Stroke 41:e117-22. 2010
  8. ncbi Infectious burden: a new risk factor and treatment target for atherosclerosis
    Mitchell S V Elkind
    Neurological Institute, 710 West 168th Street, Box 182, New York, NY 10032, USA
    Infect Disord Drug Targets 10:84-90. 2010
  9. ncbi The Levels of Inflammatory Markers in the Treatment of Stroke study (LIMITS): inflammatory biomarkers as risk predictors after lacunar stroke
    M S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Int J Stroke 5:117-25. 2010
  10. ncbi Inflammation, atherosclerosis, and stroke
    Mitchell S V Elkind
    Department of Neurology, Columbia University, New York, New York 10032, USA
    Neurologist 12:140-8. 2006

Research Grants

  1. Levels of Inflammatory Markers in Treatment of Stroke
    Mitchell Elkind; Fiscal Year: 2007
  2. Inflammatory and Infectious Burden and Risk of Stroke
    Mitchell Elkind; Fiscal Year: 2007
  3. Inflammation and Infection as Risk Factors in Stroke
    Mitchell Elkind; Fiscal Year: 2006

Detail Information

Publications87

  1. ncbi Duration of diabetes and risk of ischemic stroke: the Northern Manhattan Study
    Chirantan Banerjee
    Department of Epidemiology, Columbia University, New York, NY, USA
    Stroke 43:1212-7. 2012
    ..Diabetes increases stroke risk, but whether diabetes status immediately before stroke improves prediction and whether duration is important are less clear. We hypothesized that diabetes duration independently predicts ischemic stroke...
  2. ncbi Endothelial dysfunction is associated with carotid plaque: a cross-sectional study from the population based Northern Manhattan Study
    Tatjana Rundek
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, USA
    BMC Cardiovasc Disord 6:35. 2006
    ..The objective of this study was to determine whether endothelial dysfunction is independently associated with carotid plaque in a community of northern Manhattan...
  3. ncbi Moderate alcohol consumption is associated with better endothelial function: a cross sectional study
    Keiko Suzuki
    Division of Cardiology, Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY, USA
    BMC Cardiovasc Disord 9:8. 2009
    ....
  4. ncbi Lipids and carotid plaque in the Northern Manhattan Study (NOMAS)
    Hannah Gardener
    Department of Neurology, Miller School of Medicine, University of Miami, FL, USA
    BMC Cardiovasc Disord 9:55. 2009
    ..The objective of this cross-sectional analysis was to investigate the relation between blood lipids and carotid plaque...
  5. ncbi Statins as acute-stroke treatment
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Int J Stroke 1:224-5. 2006
  6. ncbi High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, and Divisions of Biostatistics, Joseph P Mailman School of Public Health, Columbia University, New York, New York, USA
    Arch Intern Med 166:2073-80. 2006
    ..Inflammatory markers have been associated with ischemic stroke risk and prognosis after cardiac events. Their relationship to prognosis after stroke is unsettled...
  7. ncbi Infectious burden and carotid plaque thickness: the northern Manhattan study
    Mitchell S V Elkind
    Neurological Institute, 710 West 168th Street, Box 182, New York, NY 10032, USA
    Stroke 41:e117-22. 2010
    ..The overall burden of prior infections may contribute to atherosclerosis and stroke risk. We hypothesized that serological evidence of common infections would be associated with carotid plaque thickness in a multiethnic cohort...
  8. ncbi Infectious burden: a new risk factor and treatment target for atherosclerosis
    Mitchell S V Elkind
    Neurological Institute, 710 West 168th Street, Box 182, New York, NY 10032, USA
    Infect Disord Drug Targets 10:84-90. 2010
    ..Further studies are needed, however, to determine whether an association between infectious burden and stroke exists, and whether infectious burden may be a target for intervention...
  9. ncbi The Levels of Inflammatory Markers in the Treatment of Stroke study (LIMITS): inflammatory biomarkers as risk predictors after lacunar stroke
    M S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Int J Stroke 5:117-25. 2010
    ....
  10. ncbi Inflammation, atherosclerosis, and stroke
    Mitchell S V Elkind
    Department of Neurology, Columbia University, New York, New York 10032, USA
    Neurologist 12:140-8. 2006
    ..Basic and animal research has implicated inflammatory mechanisms in the pathogenesis and progression of atherosclerosis, as well as in clinical events related to plaque rupture and other atherothrombotic events...
  11. ncbi Levels of acute phase proteins remain stable after ischemic stroke
    Mitchell S V Elkind
    Gertrude H, Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    BMC Neurol 6:37. 2006
    ..Inflammation and inflammatory biomarkers play an important role in atherosclerosis and cardiovascular disease. Little information is available, however, on time course of serum markers of inflammation after stroke...
  12. ncbi Infectious burden and risk of stroke: the northern Manhattan study
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Arch Neurol 67:33-8. 2010
    ....
  13. ncbi Why now? Moving from stroke risk factors to stroke triggers
    Mitchell S V Elkind
    Department of Neurology, Columbia University, New York Presbyterian Hospital, New York, New York, USA
    Curr Opin Neurol 20:51-7. 2007
    ..While chronic risk factors for stroke are reasonably well understood, the acute precipitants, or triggers, of stroke, remain relatively understudied...
  14. ncbi The Neuroprotection with Statin Therapy for Acute Recovery Trial (NeuSTART): an adaptive design phase I dose-escalation study of high-dose lovastatin in acute ischemic stroke
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Int J Stroke 3:210-8. 2008
    ..The presently described trial represents a new approach for treatment of acute ischemic stroke, as well as a novel way of conducting a phase I trial, evaluating safety and determining an optimal dose of a potential neuroprotectant drug...
  15. ncbi Lipoprotein-associated phospholipase A2 activity and risk of recurrent stroke
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, and Columbia Presbyterian Medical Center, New York Presbyterian Hospital, New York, NY, USA
    Cerebrovasc Dis 27:42-50. 2009
    ..Lp-PLA(2) mass correlates only moderately with levels of Lp-PLA(2) activity. The relationship of Lp-PLA(2) activity to risk of stroke recurrence is unknown. We hypothesized that Lp-PLA(2) activity levels would predict risk of recurrence...
  16. ncbi Inflammatory markers and stroke
    Mitchell S V Elkind
    Department of Neurology, Columbia University, New York Presbyterian Hospital, 710 West 168th Street, Box 182, New York, NY 10032, USA
    Curr Cardiol Rep 11:12-20. 2009
    ..Determining whether reduction of biomarkers reduces risk of recurrent stroke, however, requires further study before inflammatory markers become a routine part of the evaluation of stroke patients...
  17. ncbi Teaching the next generation of neurologists
    Mitchell S V Elkind
    Neurological Institute, 710 West 168th Street, New York, NY 10032, USA
    Neurology 72:657-63. 2009
    ....
  18. ncbi High-dose lovastatin for acute ischemic stroke: results of the phase I dose escalation neuroprotection with statin therapy for acute recovery trial (NeuSTART)
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, New York, N Y, USA
    Cerebrovasc Dis 28:266-75. 2009
    ..We sought to determine whether lovastatin at doses above those currently approved can be administered safely within 24 h after an acute ischemic stroke...
  19. ncbi Outcomes after stroke: risk of recurrent ischemic stroke and other events
    Mitchell S V Elkind
    Department of Neurology, Division of Stroke and Critical Care, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Am J Med 122:S7-13. 2009
    ..Future clinical trials will better define the optimal management of patients after stroke...
  20. ncbi Sex as a predictor of outcomes in patients treated with thrombolysis for acute stroke
    M S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Neurology 68:842-8. 2007
    ..To determine the association between sex and functional outcomes after thrombolytic treatment for acute ischemic stroke in the context of a clinical trial...
  21. ncbi High-sensitivity C-reactive protein predicts mortality but not stroke: the Northern Manhattan Study
    M S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurology 73:1300-7. 2009
    ..To determine whether high-sensitivity C-reactive protein (hsCRP) and serum amyloid A (SAA) predict stroke, vascular events, and mortality in a prospective cohort study...
  22. ncbi Seropositivity to Chlamydia pneumoniae is associated with risk of first ischemic stroke
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Stroke 37:790-5. 2006
    ..The objective of this study is to determine whether serological evidence of C pneumoniae infection is associated with risk of ischemic stroke...
  23. ncbi Chlamydia pneumoniae and the risk of first ischemic stroke : The Northern Manhattan Stroke Study
    M S Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, and the Columbia Presbyterian Medical Center of New York Presbyterian Hospital, New York, NY, USA
    Stroke 31:1521-5. 2000
    ..The data on its association with ischemic stroke are limited. We sought to determine whether chronic C pneumoniae infection is associated with ischemic stroke in a multi-ethnic population...
  24. ncbi High-sensitivity C-reactive protein and lipoprotein-associated phospholipase A2 stability before and after stroke and myocardial infarction
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Stroke 40:3233-7. 2009
    ..Little is known, however, about the stability of these markers over time, and in particular, about the effects of acute vascular events on these marker levels...
  25. ncbi Dr. Strangelove, or how I learned to stop worrying and love the core competencies
    Mitchell S V Elkind
    Neurological Institute, Columbia University, 710 W. 168 St, New York, NY 10032, USA
    Neurology 64:E3-6. 2005
  26. ncbi Secondary stroke prevention: review of clinical trials
    Mitchell S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Clin Cardiol 27:II25-35. 2004
    ....
  27. ncbi Direct thrombin inhibition: a novel approach to stroke prevention in patients with atrial fibrillation
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, and the Columbia University Medical Center of New York-Presbyterian Hospital, New York, USA
    Stroke 35:1519-22. 2004
  28. ncbi The role of warfarin and aspirin in secondary prevention of stroke
    Mitchell S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, 710 West 168th Street, Room 641, New York, NY 10032, USA
    Curr Cardiol Rep 6:135-42. 2004
    ..Newer antiplatelet agents, and the combination of novel agents with aspirin, are also finding a role in stroke prevention as clinical trial data become available...
  29. ncbi Hospitalization for infection and risk of acute ischemic stroke: the Cardiovascular Health Study
    Mitchell S V Elkind
    Department of Neurology, Columbia University, New York, NY, USA
    Stroke 42:1851-6. 2011
    ..Little is known about the acute precipitants of ischemic stroke, although evidence suggests infections contribute to risk. We hypothesized that acute hospitalization for infection is associated with the short-term risk of stroke...
  30. ncbi Leukocyte count is associated with aortic arch plaque thickness
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, USA
    Stroke 33:2587-92. 2002
    ..Leukocyte count has been associated with cardiovascular and cerebrovascular disease, including carotid plaque thickness, in several studies. We hypothesized that white blood cell count is associated with aortic arch plaque thickness (AAPT)...
  31. ncbi Tumor necrosis factor receptor levels are associated with carotid atherosclerosis
    Mitchell S Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, and the Columbia Presbyterian Medical Center of New York Presbyterian Hospital, New York, NY, USA
    Stroke 33:31-7. 2002
    ..We sought to determine whether tumor necrosis factor-alpha (TNF-alpha) and TNF receptor levels are associated with carotid plaque thickness...
  32. ncbi Elevated white blood cell count and carotid plaque thickness : the northern manhattan stroke study
    M S Elkind
    Department of Neurology, Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Stroke 32:842-9. 2001
    ..We sought to determine whether white blood cell count (WBC) is associated with carotid plaque thickness in a stroke-free, multiethnic cohort...
  33. ncbi Interleukin-2 levels are associated with carotid artery intima-media thickness
    Mitchell S V Elkind
    Department of Neurology, Neurology Stroke Division, College of Physicians and Surgeons, Columbia University, 710 West 168th Street, Rm 641, New York, NY 10032, USA
    Atherosclerosis 180:181-7. 2005
    ..To show that serum interleukin levels are associated with carotid intima-media thickness (IMT)...
  34. ncbi Relative elevation in baseline leukocyte count predicts first cerebral infarction
    M S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, Joseph Mailman School of Public Health, New York, NY, USA
    Neurology 64:2121-5. 2005
    ..Atherosclerosis is an inflammatory disease, and leukocyte levels are associated with future risk of ischemic cardiac disease...
  35. ncbi Moderate alcohol consumption reduces risk of ischemic stroke: the Northern Manhattan Study
    Mitchell S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Stroke 37:13-9. 2006
    ..Moderate alcohol consumption is protective against coronary disease, but its relationship to ischemic stroke (IS) is controversial...
  36. ncbi Lipid-lowering agent use at ischemic stroke onset is associated with decreased mortality
    Mitchell S V Elkind
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Neurology 65:253-8. 2005
    ..The authors hypothesized that patients with ischemic stroke taking LLAs would have better outcomes than patients not taking LLAs...
  37. ncbi Inflammatory mechanisms of stroke
    Mitchell S V Elkind
    Departments of Neurology and Epidemiology, Columbia University and New York Presbyterian Hospital, New York, NY, USA
    Stroke 41:S3-8. 2010
    ..Further studies are needed to determine the role of treatment of inflammation and infection in stroke prevention...
  38. ncbi Implications of stroke prevention trials: treatment of global risk
    Mitchell S V Elkind
    Department of Neurology, Gertrude H Sergievsky Center, College of Physicians and Surgeons, Columbia University, and Columbia University Medical Center of New York Presbyterian Hospital, New York, NY, USA
    Neurology 65:17-21. 2005
    ....
  39. ncbi Impact of innate inflammation in population studies
    Mitchell S V Elkind
    Departments of Neurology and Epidemiology, Columbia University, New York, New York, USA
    Ann N Y Acad Sci 1207:97-106. 2010
    ..These findings could have clinical implications. Further studies are needed to determine the role of innate inflammation and infection in stroke pathogenesis and prevention...
  40. ncbi Ischemic stroke subtype incidence among whites, blacks, and Hispanics: the Northern Manhattan Study
    Halina White
    Department of Neurology, College of Physicians and Surgeons, USA
    Circulation 111:1327-31. 2005
    ..32 (95% CI, 1.48 to 3.63); and cardioembolic stroke, 1.42 (95% CI, 0.97 to 2.09). CONCLUSIONS: The high ischemic stroke incidence among blacks and Hispanics compared with whites is due to higher rates of all ischemic stroke subtypes...
  41. ncbi Snoring and insomnia are not associated with subclinical atherosclerosis in the Northern Manhattan Study
    Alberto Ramos-Sepulveda
    Department of Neurology, Miller School of Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Int J Stroke 5:264-8. 2010
    ..We investigated the relationship between markers of subclinical atherosclerosis, insomnia, snoring, and carotid intima-media thickness, in the Northern Manhattan Study...
  42. ncbi Soluble tumor necrosis factor receptor 1 level is associated with left ventricular hypertrophy: the northern Manhattan study
    Yasuyoshi Takei
    Division of Cardiology, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Am J Hypertens 22:763-9. 2009
    ..We sought to evaluate whether inflammatory markers were independently associated with LVH in a multiethnic population in northern Manhattan...
  43. ncbi Metabolic syndrome increases carotid artery stiffness: the Northern Manhattan Study
    David Della-Morte
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33101, USA
    Int J Stroke 5:138-44. 2010
    ..The metabolic syndrome and its components are established cardiovascular disease risk factors and may also increase arterial stiffness; however, data regarding this are limited...
  44. ncbi Long-term functional recovery after first ischemic stroke: the Northern Manhattan Study
    Mandip S Dhamoon
    Neurological Institute, 710 W 168th Street, Box 206, New York, NY 10032
    Stroke 40:2805-11. 2009
    ..We hypothesized that patients with ischemic stroke experience functional decline over 5 years independent of recurrent stroke and other risk factors...
  45. ncbi Radiographic measures of chronic periodontitis and carotid artery plaque
    Steven P Engebretson
    Division of Periodontics, College of Physicians and Surgeons, Columbia University Medical Center, 630 W 168th St, PH7 E 125A New York, NY 10032, USA
    Stroke 36:561-6. 2005
    ..The purpose of this study was to determine whether radiographically assessed CP is associated with nonstenotic carotid artery plaque as an ultrasound measure of subclinical atherosclerosis...
  46. ncbi 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in the treatment of central nervous system diseases
    Joshua Z Willey
    Department of Neurology, Columbia University, New York, NY 10032, USA
    Arch Neurol 67:1062-7. 2010
    ....
  47. ncbi The role of indirect extracranial-intracranial bypass in the treatment of symptomatic intracranial atheroocclusive disease
    Ricardo J Komotar
    Departments of Neurological Surgery, Columbia University, 710 West 168th Street, Room 431, New York, New York 10032, USA
    J Neurosurg 110:896-904. 2009
    ..Indirect bypass via encephaloduroarteriosynangiosis offers a surgical alternative that may avoid rapid flow reversal while providing additional flow to at-risk, distal vascular territories...
  48. ncbi Social determinants of physical inactivity in the Northern Manhattan Study (NOMAS)
    Joshua Z Willey
    Department of Neurology, Neurological Institute, Columbia University, 710 West 168th Street, New York, NY 10032, USA
    J Community Health 35:602-8. 2010
    ..Physical inactivity is common, particularly in Hispanics, women, and those who are socially isolated. Public health interventions aimed at increasing physical activity in these more sedentary groups are required...
  49. ncbi Dietary total fat intake and ischemic stroke risk: the Northern Manhattan Study
    Bernadette Boden-Albala
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, N Y, USA
    Neuroepidemiology 32:296-301. 2009
    ..We hypothesized that total dietary fat as part of a Western diet is associated with increased risk of ischemic stroke...
  50. ncbi Inflammatory and neuroendocrine biomarkers of prognosis after ischemic stroke
    Mira Katan
    Stroke Division, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Expert Rev Neurother 11:225-39. 2011
    ..This aim has not been completely achieved yet for any biomarkers, but promising data are available and further studies are ongoing...
  51. ncbi Early depressed mood after stroke predicts long-term disability: the Northern Manhattan Stroke Study (NOMASS)
    Joshua Z Willey
    Department of Neurology, University of California, San Francisco, CA, USA
    Stroke 41:1896-900. 2010
    ..Depression is highly prevalent after stroke and may influence recovery. We aimed to determine whether depressed mood acutely after stroke predicts subsequent disability and mortality...
  52. ncbi Carotid plaque surface irregularity predicts ischemic stroke: the northern Manhattan study
    Shyam Prabhakaran
    The Neurological Institute, Columbia University, Stroke and Critical Care Division, 710 W 168th Street, Room 640, New York, NY 10032, USA
    Stroke 37:2696-701. 2006
    ..Plaque surface irregularities assessed by B-mode ultrasonography may help identify intermediate- to high-risk individuals beyond their vascular risk assessed by the presence of traditional risk factors...
  53. ncbi Reported alcohol consumption and cognitive decline: The northern Manhattan study
    Clinton B Wright
    Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Neuroepidemiology 27:201-7. 2006
    ..Moderate alcohol intake may slow cognitive decline, and both vascular and neurodegenerative mechanisms have been implicated...
  54. ncbi Alcohol intake, carotid plaque, and cognition: the Northern Manhattan Study
    Clinton B Wright
    Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Stroke 37:1160-4. 2006
    ..Few studies to clarify the importance of vascular disease have included direct measures of atherosclerosis or minority populations at higher risk of vascular disease and dementia...
  55. ncbi Experimental treatments for acute ischaemic stroke
    Ralph L Sacco
    Department of Neurology, College of Physicians and Surgeons Columbia University, New York, NY, USA
    Lancet 369:331-41. 2007
    ..The findings of these randomised trials are anticipated to allow improved treatment of patients with acute stroke...
  56. ncbi Risk of myocardial infarction or vascular death after first ischemic stroke: the Northern Manhattan Study
    Mandip S Dhamoon
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Stroke 38:1752-8. 2007
    ..We determined the absolute 5-year risk of cardiovascular outcomes and their predictors after first ischemic stroke in a multiethnic cohort...
  57. ncbi The metabolic syndrome and subclinical carotid atherosclerosis: the Northern Manhattan Study
    Tatjana Rundek
    Department of Neurology, Division of Stroke and Critical Care, Columbia University and Mailman School of Public Health, New York, NY, USA
    J Cardiometab Syndr 2:24-9. 2007
    ..67). Additionally, the number of MetS components was significantly associated with plaque prevalence. Further studies are needed to understand the role of the MetS in the progression from subclinical to clinical atherosclerotic disease...
  58. ncbi Diabetes, fasting glucose levels, and risk of ischemic stroke and vascular events: findings from the Northern Manhattan Study (NOMAS)
    Bernadette Boden-Albala
    Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Diabetes Care 31:1132-7. 2008
    ..We explored the relationship between FBG among diabetic subjects and risk of ischemic stroke in a multiethnic prospective cohort...
  59. ncbi Leukocyte count is associated with reduced endothelial reactivity
    Mitchell S V Elkind
    Department of Neurology, College of Physicians and Surgeons, Columbia University, and the Columbia University Medical Center of New York Presbyterian Hospital, New York, NY, USA
    Atherosclerosis 181:329-38. 2005
    ..Leukocyte count has been associated with cardiovascular and cerebrovascular disease in several studies. We hypothesized that white blood cell count is associated with endothelial reactivity...
  60. ncbi Stroke location and association with fatal cardiac outcomes: Northern Manhattan Study (NOMAS)
    Fred Rincon
    Department of Neurology, College of Physicians and Surgeons Columbia University, New York, NY 10032, USA
    Stroke 39:2425-31. 2008
    ..We sought to determine the association between stroke location and cardiac death or MI in a multiethnic community-based cohort...
  61. ncbi Do common infections cause stroke?
    Mitchell S V Elkind
    Department of Neurology, Gertrude H Sergievsky Center, Columbia University, New York Presbyterian Hospital, NY 10032, USA
    Semin Neurol 26:88-99. 2006
    ....
  62. ncbi Race/ethnic disparities in left ventricular diastolic function in a triethnic community cohort
    Cesare Russo
    Department of Medicine, Columbia University, New York, NY 10032, USA
    Am Heart J 160:152-8. 2010
    ..We sought to assess whether race-ethnic differences in diastolic function exist. Such differences may contribute to the observed disparities in cardiovascular outcomes...
  63. ncbi Metabolic syndrome, endothelial dysfunction, and risk of cardiovascular events: the Northern Manhattan Study (NOMAS)
    Takeki Suzuki
    Division of Cardiology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Am Heart J 156:405-10. 2008
    ..We tested the hypothesis that both MetS and endothelial dysfunction are vascular risk factors and provide additive prognostic values in predicting cardiovascular events in a multiethnic community sample...
  64. ncbi Construct validity of cognitive reserve in a multiethnic cohort: The Northern Manhattan Study
    Karen L Siedlecki
    Cognitive Neuroscience Division, Taub Institute for Research in Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Int Neuropsychol Soc 15:558-69. 2009
    ....
  65. ncbi Patent foramen ovale and migraine: a cross-sectional study from the Northern Manhattan Study (NOMAS)
    Tatjana Rundek
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Circulation 118:1419-24. 2008
    ..The objective of this study was to examine the association between PFO and migraine among stroke-free individuals in an urban, population-based, multiethnic cohort...
  66. ncbi Improving global vascular risk prediction with behavioral and anthropometric factors. The multiethnic NOMAS (Northern Manhattan Cohort Study)
    Ralph L Sacco
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
    J Am Coll Cardiol 54:2303-11. 2009
    ..This study sought to improve global vascular risk prediction with behavioral and anthropometric factors...
  67. ncbi Alterations in plasma complement levels after human ischemic stroke
    J Mocco
    Department of Neurological Surgery, Columbia University, New York, New York 10032, USA
    Neurosurgery 59:28-33; discussion 28-33. 2006
    ..To assess the applicability of these findings to humans, we evaluated the characteristics and time course of human complement activation after stroke...
  68. ncbi Inflammatory biomarkers of vascular risk as correlates of leukoariosis
    Clinton B Wright
    Department of Neurology, Miller School of Medicine, University of Miami, Evelyn F McKnight Center for Age related Memory Loss, Miami, FL 33136, USA
    Stroke 40:3466-71. 2009
    ..White matter hyperintensities (WMH) seen on brain MRI scans are associated with vascular risk factors and an increased risk of incident stroke, but their relation to inflammatory biomarkers is unclear...
  69. ncbi Insulin resistance and risk of ischemic stroke among nondiabetic individuals from the northern Manhattan study
    Tatjana Rundek
    Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Arch Neurol 67:1195-200. 2010
    ..Whether insulin resistance predicts ischemic stroke (IS) is still a matter of debate...
  70. ncbi Prevalence and quality of endodontic treatment in the Northern Manhattan elderly
    Chia Yi Chen
    School of Dental and Oral Surgery, Columbia University Medical Center, New York, NY, USA
    J Endod 33:230-4. 2007
    ..We conclude that apical periodontitis is widely prevalent and the technical standard of root fillings is poor in this cohort. There is a substantial need for improved dental care among the northern Manhattan elderly...
  71. ncbi Stroke in the elderly
    Mitchell S V Elkind
    Neurological Institute, 710 West 168th Street, New York, NY 10032, USA
    Mt Sinai J Med 70:27-37. 2003
    ..This review presents an update on definitions of stroke and its subtypes, stroke epidemiology, and the results of recent studies of stroke prevention and acute treatment...
  72. ncbi Clinical features, surgical treatment, and long-term outcome in adult patients with moyamoya disease. Clinical article
    Robert M Starke
    Department of Neurological Surgery, Columbia University, New York, New York 10032, USA
    J Neurosurg 111:936-42. 2009
    ..The object of this study was to report the clinical features, surgical treatment, and long-term outcomes in adults with moyamoya phenomenon treated at a single institution in the US...
  73. ncbi Migraine and cognitive function: some reassuring news
    Mitchell S V Elkind
    Neurology 64:590-1. 2005
  74. ncbi Statin therapy after stroke or transient ischemic attack
    Mitchell S V Elkind
    N Engl J Med 355:2369; author reply 2370-1. 2006
  75. ncbi Vive la difference! On potential sex differences in response to thrombolysis
    Shyam Prabhakaran
    Neurology 71:1048-9. 2008
  76. ncbi Advancing the study of stroke in women: summary and recommendations for future research from an NINDS-Sponsored Multidisciplinary Working Group
    Cheryl D Bushnell
    Department of Medicine, Division of Neurology, Duke University Medical Center, Durham, NC 27710, USA
    Stroke 37:2387-99. 2006
    ..Besides the role of estrogen there are many gaps of knowledge about issues specific to women and stroke...
  77. ncbi Hemicraniectomy for massive middle cerebral artery territory infarction: a systematic review
    Rishi Gupta
    Department of Neurology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Stroke 35:539-43. 2004
    ..CONCLUSIONS: Age may be a crucial factor in predicting functional outcome after hemicraniectomy in patients with large middle cerebral artery territory infarction...
  78. ncbi Stimulus-induced pathologic laughter due to basilar artery dissection
    Hiba Arif
    The Aga Khan University, Karachi, Pakistan
    Neurology 64:2154-5. 2005
  79. ncbi Reversible posterior leukoencephalopathy (and vasculopathy?) syndrome
    Mitchell S V Elkind
    Arch Neurol 65:1135; author reply 1136. 2008
  80. ncbi Endothelial repair capacity and migraine: the fix is in
    Mitchell S V Elkind
    Neurology 70:1506-7. 2008
  81. ncbi Magnetic resonance imaging changes in a patient with migraine attack and transient global amnesia after cardiac catheterization
    Andres Fernandez
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    CNS Spectr 10:980-3. 2005
    ..A discussion on potential explanations for this finding is made, as well as a review of the pertinent literature...
  82. ncbi Outpatient training in neurology: history and future challenges
    MaryAlice Naley
    Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Neurology 66:E1-6. 2006
    ..This article briefly reviews the history of neurology training, discusses current challenges to outpatient training, and recommends possible solutions for the future...
  83. ncbi Prognosis of transient neurological attacks
    Mitchell S V Elkind
    JAMA 299:1771; author reply 1772-3. 2008
  84. ncbi Nutritional support after ischemic stroke: more food for thought
    Neeraj Badjatia
    Arch Neurol 65:15-6. 2008
  85. ncbi Anticoagulation for secondary stroke prevention: another nail in the coffin?
    Mitchell S V Elkind
    Lancet Neurol 6:97-9. 2007
  86. ncbi Lowering cholesterol in patients with stroke: raising the standard
    Mitchell S V Elkind
    Neurology 66:1140-1. 2006
  87. ncbi Maintenance of certification: ready or not, here it comes
    John R Corboy
    Neurology 71:544-5. 2008

Research Grants11

  1. Levels of Inflammatory Markers in Treatment of Stroke
    Mitchell Elkind; Fiscal Year: 2007
    ..abstract_text> ..
  2. Inflammatory and Infectious Burden and Risk of Stroke
    Mitchell Elkind; Fiscal Year: 2007
    ..The cross-sectional associations between inflammatory and infectious markers and quantitative MRI abnormalities will also be assessed. ..
  3. Inflammation and Infection as Risk Factors in Stroke
    Mitchell Elkind; Fiscal Year: 2006
    ..Nationally recognized experts in stroke epidemiology and basic vascular biology will serve as mentors for these studies. ..