Wafaa M El-Sadr

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Modeling the impact on the HIV epidemic of treating discordant couples with antiretrovirals to prevent transmission
    Wafaa M El-Sadr
    ICAP, Mailman School of Public Health, Department of Epidemiology and Medicine at Columbia University, New York, New York 10032, USA
    AIDS 25:2295-9. 2011
  2. ncbi Scale-up of HIV treatment through PEPFAR: a historic public health achievement
    Wafaa M El-Sadr
    ICAP, Columbia University, Mailman School of Public Health, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 60:S96-104. 2012
  3. ncbi Antiretroviral therapy: a promising HIV prevention strategy?
    Wafaa M El-Sadr
    International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, NC 10032, USA
    J Acquir Immune Defic Syndr 55:S116-21. 2010
  4. ncbi No need for apologies
    Wafaa M El-Sadr
    ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 57:S68-71. 2011
  5. ncbi Scale-up of HIV care and treatment: can it transform healthcare services in resource-limited settings?
    Wafaa M El-Sadr
    International Center for AIDS Care and Treatment Programs, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    AIDS 21:S65-70. 2007
  6. ncbi CD4+ count-guided interruption of antiretroviral treatment
    W M El-Sadr
    Division of Infectious Diseases, Harlem Hospital Center and Columbia University, New York, NY 10037, USA
    N Engl J Med 355:2283-96. 2006
  7. ncbi Safety and acceptability of cellulose sulfate as a vaginal microbicide in HIV-infected women
    Wafaa M El-Sadr
    Harlem Hospital Center, 506 Lenox Avenue, New York, NY 10037, USA
    AIDS 20:1109-16. 2006
  8. ncbi Focus on women: linking HIV care and treatment with reproductive health services in the MTCT-Plus Initiative
    Landon Myer
    Columbia University, Mailman School of Public Health, New York, NY, USA
    Reprod Health Matters 13:136-46. 2005
  9. ncbi Effects of HIV disease on lipid, glucose and insulin levels: results from a large antiretroviral-naive cohort
    W M El-Sadr
    Harlem Hospital and Columbia University, New York, NY 10037, USA
    HIV Med 6:114-21. 2005
  10. ncbi A review of efficacy studies of 6-month short-course therapy for tuberculosis among patients infected with human immunodeficiency virus: differences in study outcomes
    W M El-Sadr
    Division of Infectious Diseases, Harlem Hospital Center and Columbia University, College of Physicians and Surgeons, New York, NY 10037, USA
    Clin Infect Dis 32:623-32. 2001

Research Grants

  1. HIV PREVENTION TRIAL UNIT (PRIDE NYC PROGRAM)
    Wafaa El Sadr; Fiscal Year: 2006
  2. Training in the Epidemiology of Infectious Disease
    Wafaa El Sadr; Fiscal Year: 2007
  3. HARLEM AIDS TREATMENT GROUP-'CPCRA'
    Wafaa El Sadr; Fiscal Year: 2006
  4. Centers for Innovative Research to Control AIDS
    Wafaa El Sadr; Fiscal Year: 2007
  5. TUBERCULOSIS ADHERENCE PARTNERSHIP ALLIANCE STUDY
    Wafaa El Sadr; Fiscal Year: 2004
  6. Enhance Prevention in Couples (EPIC)
    Wafaa M El Sadr; Fiscal Year: 2010

Detail Information

Publications50

  1. ncbi Modeling the impact on the HIV epidemic of treating discordant couples with antiretrovirals to prevent transmission
    Wafaa M El-Sadr
    ICAP, Mailman School of Public Health, Department of Epidemiology and Medicine at Columbia University, New York, New York 10032, USA
    AIDS 25:2295-9. 2011
    ..The HPTN 052 study demonstrated a 96% reduction in HIV transmission in discordant couples using antiretroviral therapy (ART)...
  2. ncbi Scale-up of HIV treatment through PEPFAR: a historic public health achievement
    Wafaa M El-Sadr
    ICAP, Columbia University, Mailman School of Public Health, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 60:S96-104. 2012
    ..However, much remains to be accomplished to achieve universal access, to enhance the quality of programs, to ensure retention of patients in care, and to continue to strengthen health systems...
  3. ncbi Antiretroviral therapy: a promising HIV prevention strategy?
    Wafaa M El-Sadr
    International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, NC 10032, USA
    J Acquir Immune Defic Syndr 55:S116-21. 2010
    ....
  4. ncbi No need for apologies
    Wafaa M El-Sadr
    ICAP, Columbia University, 722 West 168th Street, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 57:S68-71. 2011
    ....
  5. ncbi Scale-up of HIV care and treatment: can it transform healthcare services in resource-limited settings?
    Wafaa M El-Sadr
    International Center for AIDS Care and Treatment Programs, Columbia University Mailman School of Public Health, New York, New York 10032, USA
    AIDS 21:S65-70. 2007
    ..In order to determine these broader effects, mechanisms need to be established that enable relevant research and evaluation questions to be answered...
  6. ncbi CD4+ count-guided interruption of antiretroviral treatment
    W M El-Sadr
    Division of Infectious Diseases, Harlem Hospital Center and Columbia University, New York, NY 10037, USA
    N Engl J Med 355:2283-96. 2006
    ..Despite declines in morbidity and mortality with the use of combination antiretroviral therapy, its effectiveness is limited by adverse events, problems with adherence, and resistance of the human immunodeficiency virus (HIV)...
  7. ncbi Safety and acceptability of cellulose sulfate as a vaginal microbicide in HIV-infected women
    Wafaa M El-Sadr
    Harlem Hospital Center, 506 Lenox Avenue, New York, NY 10037, USA
    AIDS 20:1109-16. 2006
    ..We conducted this study to evaluate the safety and acceptability of 6% cellulose sulfate (CS) gel as a vaginal microbicide in sexually abstinent and active HIV-infected women...
  8. ncbi Focus on women: linking HIV care and treatment with reproductive health services in the MTCT-Plus Initiative
    Landon Myer
    Columbia University, Mailman School of Public Health, New York, NY, USA
    Reprod Health Matters 13:136-46. 2005
    ....
  9. ncbi Effects of HIV disease on lipid, glucose and insulin levels: results from a large antiretroviral-naive cohort
    W M El-Sadr
    Harlem Hospital and Columbia University, New York, NY 10037, USA
    HIV Med 6:114-21. 2005
    ..This study was designed to explore these issues...
  10. ncbi A review of efficacy studies of 6-month short-course therapy for tuberculosis among patients infected with human immunodeficiency virus: differences in study outcomes
    W M El-Sadr
    Division of Infectious Diseases, Harlem Hospital Center and Columbia University, College of Physicians and Surgeons, New York, NY 10037, USA
    Clin Infect Dis 32:623-32. 2001
    ..4%. Although the rate of relapse appeared to be higher in some studies of HIV-infected patients with tuberculosis, this review demonstrates the limitation in the use of relapse as the exclusive outcome of interest when comparing studies...
  11. ncbi A randomized trial of daily and thrice-weekly trimethoprim-sulfamethoxazole for the prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected persons. Terry Beirn Community Programs for Clinical Research on AIDS (CPCRA)
    W M El-Sadr
    Harlem Hospital Center and Columbia University, College of Physicians and Surgeons, New York, New York 10037, USA
    Clin Infect Dis 29:775-83. 1999
    ..Daily trimethoprim-sulfamethoxazole may offer advantages as a first choice for PCP prophylaxis; thrice-weekly dosing is an appropriate option for patients intolerant of the daily dose...
  12. ncbi Discontinuation of prophylaxis for Mycobacterium avium complex disease in HIV-infected patients who have a response to antiretroviral therapy. Terry Beirn Community Programs for Clinical Research on AIDS
    W M El-Sadr
    Division of Infectious Diseases, Harlem Hospital Center and Columbia University College of Physicians and Surgeons, New York, NY 10037, USA
    N Engl J Med 342:1085-92. 2000
    ..However, there is uncertainty about whether prophylaxis should be continued in patients whose CD4+ cell counts have increased substantially with antiviral therapy...
  13. ncbi Factors associated with late antiretroviral therapy initiation among adults in Mozambique
    Maria Lahuerta
    Mailman School of Public Health, ICAP Columbia University, New York, New York, United States of America
    PLoS ONE 7:e37125. 2012
    ....
  14. ncbi CD4+ cell count testing more effective than HIV disease clinical staging in identifying pregnant and postpartum women eligible for antiretroviral therapy in resource-limited settings
    Rosalind J Carter
    International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 55:404-10. 2010
    ..However, there have been few investigations of the performance of ART eligibility criteria in pregnant and postpartum women in resource-limited settings...
  15. ncbi HIV, aging and continuity care: strengthening health systems to support services for noncommunicable diseases in low-income countries
    Miriam Rabkin
    ICAP Columbia, Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA
    AIDS 26:S77-83. 2012
    ..These systems, lessons and resources can also be leveraged to support the burgeoning numbers of HIV-negative individuals with chronic NCD in need of ongoing care...
  16. ncbi Prevention of mother-to-child transmission services as a gateway to family-based human immunodeficiency virus care and treatment in resource-limited settings: rationale and international experiences
    Elaine J Abrams
    International Center for HIV AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Obstet Gynecol 197:S101-6. 2007
    ....
  17. ncbi Initiation of antiretroviral therapy among pregnant women in resource-limited countries: CD4+ cell count response and program retention
    Patricia L Toro
    International Center for AIDS Care and Treatment Programs, Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA
    AIDS 24:515-24. 2010
    ..Few data are available from resource-limited countries on long-term outcomes of HIV-infected women who initiate antiretroviral therapy (ART) during pregnancy...
  18. ncbi HIV-associated tuberculosis: diagnostic and treatment challenges
    Wafaa M El-Sadr
    International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, New York, USA
    Semin Respir Crit Care Med 29:525-31. 2008
    ..Also needed are effective and feasible strategies to optimize management of both conditions in the coinfected patient...
  19. ncbi Why reinvent the wheel? Leveraging the lessons of HIV scale-up to confront non-communicable diseases
    Miriam Rabkin
    Department of Medicine, Columbia University College of Physicians and Surgeons and Mailman School of Public Health, New York, NY, USA
    Glob Public Health 6:247-56. 2011
    ..As such, they might be used to 'jumpstart' the development of initiatives to provide prevention, care and treatment services for NCDs and other chronic conditions...
  20. ncbi The HIV care continuum: no partial credit given
    Margaret L McNairy
    ICAP, Mailman School of Public Health, Columbia University, NY 10032, USA
    AIDS 26:1735-8. 2012
    ....
  21. ncbi Association of adherence support and outreach services with total attrition, loss to follow-up, and death among ART patients in sub-Saharan Africa
    Matthew R Lamb
    International Center for AIDS Care and Treatment Programs ICAP, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e38443. 2012
    ..Loss to follow-up (LTF) after antiretroviral therapy (ART) initiation is common in HIV clinics. We examined the effect of availability of adherence support and active patient outreach services on patient attrition following ART initiation...
  22. ncbi Lessons from Africa
    Miriam Rabkin
    International Center for AIDS Care and Treatment Programs, Columbia University Mailman School of Public Health, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 55:S141-3. 2010
    ..Ten years later, lessons from Africa learned from the remarkable achievements of HIV programs now have the potential to inform the response to the US domestic epidemic...
  23. ncbi Integrating HIV care and HIV prevention: legal, policy and programmatic recommendations
    Robert H Remien
    HIV Center for Clinical and Behavioral Studies, NY State Psychiatric Institute and Columbia University, New York, New York, USA
    AIDS 22:S57-65. 2008
    ..We offer specific recommendations for action in the domains of healthcare policy and practice in order better to utilize the advances in HIV treatment to advance HIV prevention...
  24. ncbi Integration of tuberculosis and HIV services in sub-Saharan Africa: lessons learned
    Andrea A Howard
    International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Clin Infect Dis 50:S238-44. 2010
    ....
  25. ncbi Lessons from Harlem: Relevance to a global epidemic
    Elaine J Abrams
    Department of Pediatrics, Harlem Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Acquir Immune Defic Syndr 52:S24-6. 2009
    ..Lessons learned from this effort have been applied to other health threats in the community and could inform the global response to HIV...
  26. ncbi The President's Emergency Plan for AIDS Relief--is the emergency over?
    Wafaa M El-Sadr
    International Center for AIDS Care and Treatment Programs and Mailman School of Public Health, Columbia University, New York, USA
    N Engl J Med 359:553-5. 2008
  27. ncbi The impact of HIV scale-up on health systems: A priority research agenda
    Miriam Rabkin
    Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 52:S6-11. 2009
    ....
  28. ncbi Sexual behaviors and condom use of HIV-infected men and women of color attending a treatment and care clinic
    Judith Absalon
    Center for Infectious Diseases Epidemiologic Research, Mailman School of Public Health, Division of Infectious Diseases, Harlem Hospital Center, Columbia University, New York, NY, USA
    J Natl Med Assoc 97:25S-31S. 2005
    ..Limited data are available regarding high-risk sexual behaviors among HIV-infected African Americans and Latinos who receive ongoing care in clinical settings...
  29. ncbi Tuberculosis knowledge, attitudes, and beliefs in foreign-born and US-born patients with latent tuberculosis infection
    Paul W Colson
    Charles P Felton National Tuberculosis Center, Columbia University, New York, NY 10027, USA
    J Immigr Minor Health 12:859-66. 2010
    ..Improved understanding of foreign-born patients' KAB may contribute to the reduction of barriers to treatment and improved outcomes...
  30. ncbi Acceptability of tenofovir gel as a vaginal microbicide by US male participants in a Phase I clinical trial (HPTN 050)
    Alex Carballo-Dieguez
    HIV Center for Clinical and Behavioral StudiesNew York State Psychiatric Institute, New York, NY 10032, USA
    AIDS Care 19:1026-31. 2007
    ..Consistent microbicide use may be contingent on its ease of incorporation into typical sexual practices, type of sexual partnership and contextual issues...
  31. ncbi Sensitivity analysis and potential uses of a novel gamma interferon release assay for diagnosis of tuberculosis
    Simon J Tsiouris
    Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, Room 710, New York, NY 10032, USA
    J Clin Microbiol 44:2844-50. 2006
    ..The TST combined with IGRA or with a single sputum smear may have a role in excluding the diagnosis of TB in some settings...
  32. ncbi Postprandial response to a physiologic caloric load in HIV-positive patients receiving protease inhibitor-based or nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    Asha Thomas-Geevarghese
    Department of Medicine and the General Clinical Research Center, Harlem Hospital Center and Columbia University, New York, NY, USA
    Am J Clin Nutr 82:146-54. 2005
    ..CONCLUSIONS: Despite baseline differences, incremental triacylglycerol and insulin responses to a physiologic caloric load among HIV-positive patients were not significantly affected by differences in the type of antiretroviral therapy...
  33. ncbi Patients enrolled in HIV care in Mozambique: baseline characteristics and follow-up outcomes
    Maria Lahuerta
    ICAP Columbia University, Mailman School of Public Health, New York, NY 10032, USA
    J Acquir Immune Defic Syndr 58:e75-86. 2011
    ..To utilize routinely collected service delivery data from HIV care and treatment clinics in Mozambique to describe the patient population and programmatic outcomes from 2003 to 2009...
  34. ncbi Tuberculosis and HIV-needed: a new paradigm for the control and management of linked epidemics
    Simon J Tsiouris
    Division of Infectious Diseases and Department of Epidemiology, College of Physicians and Surgeons and Mailman School of Public Health, Columbia University, New York, NY, USA
    MedGenMed 9:62. 2007
  35. ncbi Gender and care: access to HIV testing, care, and treatment
    Robert H Remien
    HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University, New York, NY, USA
    J Acquir Immune Defic Syndr 51:S106-10. 2009
    ..Culturally specific policy and programmatic recommendations for improving HIV prevention and treatment in the MENA region are offered...
  36. ncbi Safety and tolerability of tenofovir vaginal gel in abstinent and sexually active HIV-infected and uninfected women
    Kenneth H Mayer
    Miriam Hospital Brown University, Providence, Rhode Island 02906, USA
    AIDS 20:543-51. 2006
    ....
  37. ncbi Predictors of hypertension and changes of blood pressure in HIV-infected patients
    Rodolphe Thiebaut
    INSERM E0338 epsilont U593, ISPED, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Antivir Ther 10:811-23. 2005
    ..We assessed predictors of changes in systolic (SBP) and diastolic (DBP) blood pressure during follow-up and of the development of hypertension in HIV-infected individuals...
  38. ncbi Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study
    Rainer Weber
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital, CH 809a Zurich, Switzerland
    Arch Intern Med 166:1632-41. 2006
    ..An increasing proportion of deaths among human immunodeficiency virus (HIV)-infected persons with access to combination antiretroviral therapy (cART) are due to complications of liver diseases...
  39. ncbi Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine
    Judith C Shlay
    Denver Community Programs for Clinical Research on AIDS, Denver Public Health, University of Colorado Health Sciences Center, Denver, CO, USA
    J Acquir Immune Defic Syndr 38:147-55. 2005
    ..Early and sustained increases in insulin and insulin resistance were seen only for ddI+d4T. In this prospective study, metabolic and body composition changes varied according to whether subjects received ddI+d4T or ABC+3TC...
  40. ncbi Long-term body composition and metabolic changes in antiretroviral naive persons randomized to protease inhibitor-, nonnucleoside reverse transcriptase inhibitor-, or protease inhibitor plus nonnucleoside reverse transcriptase inhibitor-based strategy
    Judith C Shlay
    Denver Community Programs for Clinical Research on AIDS, Department of Family Medicine, University of Colorado Health Sciences Center, and Denver Public Health, 605 Bannock Street, Denver, CO 80204, USA
    J Acquir Immune Defic Syndr 44:506-17. 2007
    ....
  41. ncbi Determination of the underlying cause of death in three multicenter international HIV clinical trials
    Alan R Lifson
    University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    HIV Clin Trials 9:177-85. 2008
    ..Describe processes and challenges for an Endpoint Review Committee (ERC) in determining and adjudicating underlying causes of death in HIV clinical trials...
  42. ncbi Asymptomatic myocardial ischaemia in HIV-infected adults
    Andrew Carr
    St Vincent s Hospital, University of New South Wales, Sydney, Australia
    AIDS 22:257-67. 2008
    ..Asymptomatic ischaemic heart disease (IHD) in HIV-infected patients has not been studied...
  43. ncbi Combination antiretroviral therapy and the risk of myocardial infarction
    Nina Friis-Møller
    N Engl J Med 349:1993-2003. 2003
    ..It remains controversial whether exposure to combination antiretroviral treatment increases the risk of myocardial infarction...
  44. ncbi Effects of HIV infection on body composition changes among men of different racial/ethnic origins
    Fehmida Visnegarwala
    AbsoluteCare Medical Center, Atlanta, Georgia 30329, USA
    HIV Clin Trials 8:145-54. 2007
    ..We hypothesized that the effect of HIV infection will be uniform across all racial/ethnic groups...
  45. ncbi Increased lipoprotein remnant cholesterol levels in HIV-positive patients during antiretroviral therapy
    Erdembileg Anuurad
    Department of Medicine, University of California, Davis, CA 95817, USA
    Atherosclerosis 198:192-7. 2008
    ..024, ANOVA). In conclusion, during HIV conditions, HAART resulted in a pro-atherogenic pattern with accumulation of remnant lipoproteins...
  46. ncbi Implementing antiretroviral therapy in resource-constrained settings: opportunities and challenges in integrating HIV and tuberculosis care
    Salim S Abdool-Karim
    CAPRISA, University of KwaZulu-Natal, South Africa
    AIDS 18:975-9. 2004
  47. ncbi Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approach
    Besigin Tonwe Gold
    MTCT Plus Programme, ACONDA, Abidjan, Cote d Ivoire
    PLoS Med 4:e257. 2007
    ....
  48. ncbi Reporting and evaluation of HIV-related clinical endpoints in two multicenter international clinical trials
    Alan R Lifson
    Department of Epidemiology and Community Health, University of Minnesota, 1300 South Second Street, Minneapolis, MN 55454, USA
    HIV Clin Trials 7:125-41. 2006
    ..The processes for reporting and review of progression of HIV disease clinical endpoints are described for two large phase III international clinical trials...
  49. ncbi Reproductive decisions in HIV-infected individuals
    Landon Myer
    Infectious Diseases Epidemiology Unit, School of Public Health and Family Medicine, University of Cape Town, Observatory 7925, Cape Town, South Africa
    Lancet 366:698-700. 2005
  50. ncbi Acceptability of tenofovir gel as a vaginal microbicide among women in a phase I trial: a mixed-methods study
    Rochelle K Rosen
    The Miriam Hospital, Providence, Rhode Island 02903, USA
    J Womens Health (Larchmt) 17:383-92. 2008
    ..The impact of acceptability factors on use of the gel and the relationship between qualitative and quantitative acceptability data are explored...

Research Grants17

  1. HIV PREVENTION TRIAL UNIT (PRIDE NYC PROGRAM)
    Wafaa El Sadr; Fiscal Year: 2006
    ..abstract_text> ..
  2. Training in the Epidemiology of Infectious Disease
    Wafaa El Sadr; Fiscal Year: 2007
    ..The Program has a rigorous evaluation plan that includes process and outcome measures. These features of the Training Program, combined with its rich array of resources, will guide this program to the achievement of its goals. ..
  3. HARLEM AIDS TREATMENT GROUP-'CPCRA'
    Wafaa El Sadr; Fiscal Year: 2006
    ..They also are committed to the conduct of large long-term studies as a means of answering key questions in HIV management that cannot be answered through shorter trials. ..
  4. Centers for Innovative Research to Control AIDS
    Wafaa El Sadr; Fiscal Year: 2007
    ..administrative component: ..
  5. TUBERCULOSIS ADHERENCE PARTNERSHIP ALLIANCE STUDY
    Wafaa El Sadr; Fiscal Year: 2004
    ..abstract_text> ..
  6. Enhance Prevention in Couples (EPIC)
    Wafaa M El Sadr; Fiscal Year: 2010
    ..They have extensive experience in establishing programs in sub Saharan Africa and have successfully designed and implemented prevention studies in diverse settings. ..