Linda S Einbond

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, HHSC 1508, 701 W 168th Street, New York, NY 10032, USA
    Biochem Biophys Res Commun 375:608-13. 2008
  2. ncbi Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells
    Linda Saxe Einbond
    Herbert Irvign Comperhensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Breast Cancer Res Treat 83:221-31. 2004
  3. ncbi Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, 701 W 168th Street, New York, NY 10032, USA
    Planta Med 72:1200-6. 2006
  4. ncbi Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Anticancer Res 27:697-712. 2007
  5. ncbi The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Int J Cancer 121:2073-83. 2007
  6. ncbi Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, HHSC 1509, 701 W 168th Street, New York, NY 10032, USA
    Phytomedicine 15:504-11. 2008
  7. ncbi Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats
    Linda Saxe Einbond
    Columbia Universty College of Physicians and Surgeons, New York, NY 10032, USA
    Fundam Clin Pharmacol 23:311-21. 2009
  8. ncbi Polyphenolic constituents of Actaea racemosa
    Paiboon Nuntanakorn
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, New York 10468, USA
    J Nat Prod 69:314-8. 2006

Research Grants

  1. Anticancer Potential of Black Cohosh on Breast Cancer
    LINDA EINBOND; Fiscal Year: 2007

Detail Information

Publications8

  1. ncbi Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, College of Physicians and Surgeons, Columbia University, HHSC 1508, 701 W 168th Street, New York, NY 10032, USA
    Biochem Biophys Res Commun 375:608-13. 2008
    ..Actein and digitoxin may be a useful synergistic combination for cancer chemoprevention and/or therapy...
  2. ncbi Growth inhibitory activity of extracts and purified components of black cohosh on human breast cancer cells
    Linda Saxe Einbond
    Herbert Irvign Comperhensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Breast Cancer Res Treat 83:221-31. 2004
    ..Further studies are in progress to identify the mechanisms by which actein and related compounds present in black cohosh inhibit growth of human breast cancer cells...
  3. ncbi Actein and a fraction of black cohosh potentiate antiproliferative effects of chemotherapy agents on human breast cancer cells
    Linda Saxe Einbond
    Columbia University College of Physicians and Surgeons, 701 W 168th Street, New York, NY 10032, USA
    Planta Med 72:1200-6. 2006
    ....
  4. ncbi Gene expression analysis of the mechanisms whereby black cohosh inhibits human breast cancer cell growth
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Anticancer Res 27:697-712. 2007
    ..Our aim is to identify alterations in gene expression induced by treatment with a methanolic extract (MeOH) of black cohosh...
  5. ncbi The growth inhibitory effect of actein on human breast cancer cells is associated with activation of stress response pathways
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Int J Cancer 121:2073-83. 2007
    ..Since actein activated transcription factors that enhance apoptosis, and repressed cell cycle genes, it may be useful in the prevention and therapy of breast cancer...
  6. ncbi Growth inhibitory activity of extracts and compounds from Cimicifuga species on human breast cancer cells
    Linda Saxe Einbond
    Department of Rehabilitation Medicine, Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, HHSC 1509, 701 W 168th Street, New York, NY 10032, USA
    Phytomedicine 15:504-11. 2008
    ....
  7. ncbi Actein activates stress- and statin-associated responses and is bioavailable in Sprague-Dawley rats
    Linda Saxe Einbond
    Columbia Universty College of Physicians and Surgeons, New York, NY 10032, USA
    Fundam Clin Pharmacol 23:311-21. 2009
    ..The serum level of actein peaked at 2.4 microg/mL at 6 h. Actein's ability to alter pathways involved in lipid disorders and carcinogenesis may make it a new agent for preventing and treating these major disorders...
  8. ncbi Polyphenolic constituents of Actaea racemosa
    Paiboon Nuntanakorn
    Department of Biological Sciences, Lehman College and The Graduate Center, The City University of New York, Bronx, New York 10468, USA
    J Nat Prod 69:314-8. 2006
    ..Compounds 1 and 2 also exhibited a small stimulating effect on the growth of MCF-7 breast cancer cell proliferation 1.24-fold (14 microM) and 1.14-fold (10 microM), respectively, compared to untreated cells...

Research Grants1

  1. Anticancer Potential of Black Cohosh on Breast Cancer
    LINDA EINBOND; Fiscal Year: 2007
    ..This research project could identify new approaches to breast cancer prevention and therapy. ..