Michael R Drew

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Adult hippocampal neurogenesis as target for the treatment of depression
    Michael R Drew
    Center for Neurobiology and Behavior, Columbia University, NY, USA
    CNS Neurol Disord Drug Targets 6:205-18. 2007
  2. ncbi request reprint Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing
    Michael R Drew
    Division of Integrative Neuroscience, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Neurosci 27:7731-9. 2007
  3. ncbi request reprint Temporal specificity of extinction in autoshaping
    Michael R Drew
    Department of Psychology, Columbia University, New York, NY, USA
    J Exp Psychol Anim Behav Process 30:163-76. 2004
  4. ncbi request reprint Temporal control of conditioned responding in goldfish
    Michael R Drew
    Department of Psychology, Columbia University, New York, NY, USA
    J Exp Psychol Anim Behav Process 31:31-9. 2005
  5. pmc Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits
    Ryan D Ward
    Department of Psychiatry, Columbia University, NY State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Behav Neurosci 123:720-30. 2009
  6. pmc Arrest of adult hippocampal neurogenesis in mice impairs single- but not multiple-trial contextual fear conditioning
    Michael R Drew
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Behav Neurosci 124:446-54. 2010
  7. pmc 4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning
    Christine A Denny
    Department of Biological Sciences, Columbia University, New York, New York, USA
    Hippocampus 22:1188-201. 2012
  8. pmc Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
    Michael D Saxe
    Center for Neurobiology and Behavior, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 103:17501-6. 2006
  9. pmc An animal model of a behavioral intervention for depression
    Daniela D Pollak
    Department of Neuroscience, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Neuron 60:149-61. 2008
  10. ncbi request reprint Effects of dopamine antagonists on the timing of two intervals
    Michael R Drew
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Pharmacol Biochem Behav 75:9-15. 2003

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Adult hippocampal neurogenesis as target for the treatment of depression
    Michael R Drew
    Center for Neurobiology and Behavior, Columbia University, NY, USA
    CNS Neurol Disord Drug Targets 6:205-18. 2007
    ..We review the cellular pathways through which antidepressant drugs boost neurogenesis and present several hypotheses about how DG neurogenesis may be instrumental in the therapeutic effects of these drugs...
  2. ncbi request reprint Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing
    Michael R Drew
    Division of Integrative Neuroscience, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Neurosci 27:7731-9. 2007
    ..Moreover, overexpression of D2 under pathological conditions such as schizophrenia and Parkinson's disease could give rise to motivational and timing deficits...
  3. ncbi request reprint Temporal specificity of extinction in autoshaping
    Michael R Drew
    Department of Psychology, Columbia University, New York, NY, USA
    J Exp Psychol Anim Behav Process 30:163-76. 2004
    ..Transfer of extinction to the training CS is controlled by the similarity between the extinction and training CSs. Extinction learning is temporally specific...
  4. ncbi request reprint Temporal control of conditioned responding in goldfish
    Michael R Drew
    Department of Psychology, Columbia University, New York, NY, USA
    J Exp Psychol Anim Behav Process 31:31-9. 2005
    ..The data suggest that times are learned early in training, and, contrary to I. P. Pavlov's (1927/1960) concept of "inhibition of delay," that timing is learning when to respond rather than learning when not to respond...
  5. pmc Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits
    Ryan D Ward
    Department of Psychiatry, Columbia University, NY State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    Behav Neurosci 123:720-30. 2009
    ..These results suggest that striatal D2 overexpression impairs timing by decreasing motivation and through its impact on working memory and/or sustained attention...
  6. pmc Arrest of adult hippocampal neurogenesis in mice impairs single- but not multiple-trial contextual fear conditioning
    Michael R Drew
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Behav Neurosci 124:446-54. 2010
    ..These results indicate that adult hippocampal neurogenesis is required for CFC in mice only when brief training is provided...
  7. pmc 4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning
    Christine A Denny
    Department of Biological Sciences, Columbia University, New York, New York, USA
    Hippocampus 22:1188-201. 2012
    ..These data suggest that the transient enhancement of plasticity observed in young adult-born neurons contributes to cognitive functions...
  8. pmc Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus
    Michael D Saxe
    Center for Neurobiology and Behavior, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 103:17501-6. 2006
    ..These data show that new hippocampal neurons can be preferentially recruited over mature granule cells in vitro and may provide a framework for how this small cell population can influence behavior...
  9. pmc An animal model of a behavioral intervention for depression
    Daniela D Pollak
    Department of Neuroscience, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Neuron 60:149-61. 2008
    ..These data suggest that learned safety is an animal model of a behavioral antidepressant that shares some neuronal hallmarks of pharmacological antidepressants but is mediated by different molecular pathways...
  10. ncbi request reprint Effects of dopamine antagonists on the timing of two intervals
    Michael R Drew
    Department of Psychology, Columbia University, New York, NY 10027, USA
    Pharmacol Biochem Behav 75:9-15. 2003
    ..In addition, there was evidence of HAL- and SCH-induced delays in response initiation that were more severe for the long interval, perhaps owing to its status as a weaker conditioned stimulus...
  11. ncbi request reprint Dentate gyrus neurogenesis and depression
    Amar Sahay
    Department of Neuroscience, Columbia University, New York, NY 10032, USA
    Prog Brain Res 163:697-722. 2007
    ..The implications of these findings are discussed to reevaluate the role of hippocampal neurogenesis in MDD...
  12. ncbi request reprint Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment
    Dar Meshi
    Department of Biological Sciences, Columbia University, New York, New York 10027, USA
    Nat Neurosci 9:729-31. 2006
    ..We report that environmental enrichment alters behavior in mice regardless of their hippocampal neurogenic capability, providing evidence that the newborn cells do not mediate these effects of enrichment...