Affiliation: Columbia University
- A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cellsT Dorai
Molecular Urology Laboratory, Columbia University College of Physicians and Surgeons, New York, NY, USA
Int J Cancer 82:846-52. 1999..Our results support further development of this adenovirus/anti-bcl-2 ribozyme for potential gene therapeutic purposes in certain forms of hormone-resistant prostate cancer where over-expression of bcl-2 proto-oncogene is indicated...
- Therapeutic potential of curcumin in human prostate cancer. II. Curcumin inhibits tyrosine kinase activity of epidermal growth factor receptor and depletes the proteinT Dorai
Department of Urology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Mol Urol 4:1-6. 2000....
- Therapeutic potential of curcumin in human prostate cancer. III. Curcumin inhibits proliferation, induces apoptosis, and inhibits angiogenesis of LNCaP prostate cancer cells in vivoT Dorai
Molecular Urology Laboratory, Department of Urology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Prostate 47:293-303. 2001..To extend these observations made in vitro and to study the efficacy of this potential anti-cancer agent in vivo, the growth of LNCaP cells as heterotopically implanted tumors in nude mice was followed...