E D Collins

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Amantadine does not modulate reinforcing, subjective, or cardiovascular effects of cocaine in humans
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA
    Pharmacol Biochem Behav 76:401-7. 2003
  2. ncbi request reprint Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    JAMA 294:903-13. 2005
  3. ncbi request reprint The effects of memantine on the subjective, reinforcing and cardiovascular effects of cocaine in humans
    E D Collins
    Division on Substance Abuse, New York State Psychiatric Institute, New York, USA
    Behav Pharmacol 9:587-98. 1998
  4. ncbi request reprint Effects of an alternative reinforcer on intravenous heroin self-administration by humans
    S D Comer
    Division on Substance Abuse, New York State Psychiatric Institute, New York 10032, USA
    Eur J Pharmacol 345:13-26. 1998
  5. ncbi request reprint Comparison of intravenous and intranasal heroin self-administration by morphine-maintained humans
    S D Comer
    New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, NY 10032, USA
    Psychopharmacology (Berl) 143:327-38. 1999
  6. ncbi request reprint Buprenorphine sublingual tablets: effects on IV heroin self-administration by humans
    S D Comer
    New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, NY 10032, USA
    Psychopharmacology (Berl) 154:28-37. 2001
  7. ncbi request reprint Effect of a selective dopamine D1 agonist (ABT-431) on smoked cocaine self-administration in humans
    M Haney
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Psychopharmacology (Berl) 143:102-10. 1999
  8. ncbi request reprint Ketoconazole attenuates the cortisol response but not the subjective effects of smoked cocaine in humans
    A S Ward
    Division on Substance Abuse, New York State Psychiatric Institute, NY 10032, USA
    Behav Pharmacol 9:577-86. 1998
  9. ncbi request reprint Blockade of cocaine-induced increases in adrenocorticotrophic hormone and cortisol does not attenuate the subjective effects of smoked cocaine in humans
    A S Ward
    Division on Substance Abuse, New York State Psychiatric Institute, NY 10032, USA
    Behav Pharmacol 10:523-9. 1999
  10. ncbi request reprint Sensitive and selective liquid chromatographic assay of memantine in plasma with fluorescence detection after pre-column derivatization
    R F Suckow
    Analytical Psychopharmacology Laboratory, New York State Psychiatric Institute, NY 10032, USA
    J Chromatogr B Biomed Sci Appl 729:217-24. 1999

Detail Information

Publications24

  1. ncbi request reprint Amantadine does not modulate reinforcing, subjective, or cardiovascular effects of cocaine in humans
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA
    Pharmacol Biochem Behav 76:401-7. 2003
    ..These findings, taken together with the decidedly mixed literature, suggest that amantadine (100 mg bid) will not have a role in the treatment of cocaine dependence...
  2. ncbi request reprint Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    JAMA 294:903-13. 2005
    ..Rapid opioid detoxification with opioid antagonist induction using general anesthesia has emerged as an expensive, potentially dangerous, unproven approach to treat opioid dependence...
  3. ncbi request reprint The effects of memantine on the subjective, reinforcing and cardiovascular effects of cocaine in humans
    E D Collins
    Division on Substance Abuse, New York State Psychiatric Institute, New York, USA
    Behav Pharmacol 9:587-98. 1998
    ..These data suggest that NMDA antagonists may have limited usefulness as treatment medications for cocaine abuse...
  4. ncbi request reprint Effects of an alternative reinforcer on intravenous heroin self-administration by humans
    S D Comer
    Division on Substance Abuse, New York State Psychiatric Institute, New York 10032, USA
    Eur J Pharmacol 345:13-26. 1998
    ..Consistent with previous studies, the present results demonstrate that alternative reinforcers, depending on magnitude, are effective in reducing heroin use in opioid-dependent individuals...
  5. ncbi request reprint Comparison of intravenous and intranasal heroin self-administration by morphine-maintained humans
    S D Comer
    New York State Psychiatric Institute, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, NY 10032, USA
    Psychopharmacology (Berl) 143:327-38. 1999
    ..The results also underscore the importance of evaluating drug self-administration in the evaluation of the abuse liability of drugs...
  6. ncbi request reprint Buprenorphine sublingual tablets: effects on IV heroin self-administration by humans
    S D Comer
    New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, NY 10032, USA
    Psychopharmacology (Berl) 154:28-37. 2001
    ..However, because recent research suggests that the liquid and tablet differ in bio-availability, it is unclear what dose of the buprenorphine tablet effectively antagonizes the reinforcing effects of heroin...
  7. ncbi request reprint Effect of a selective dopamine D1 agonist (ABT-431) on smoked cocaine self-administration in humans
    M Haney
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Psychopharmacology (Berl) 143:102-10. 1999
    ..Data in laboratory animals suggest that D1 receptor agonists may have potential utility for the treatment of cocaine abuse...
  8. ncbi request reprint Ketoconazole attenuates the cortisol response but not the subjective effects of smoked cocaine in humans
    A S Ward
    Division on Substance Abuse, New York State Psychiatric Institute, NY 10032, USA
    Behav Pharmacol 9:577-86. 1998
    ..To the extent that self-administration can be predicted by subjective effects, these results further argue that the HPA axis does not play a critical role in cocaine self-administration by humans...
  9. ncbi request reprint Blockade of cocaine-induced increases in adrenocorticotrophic hormone and cortisol does not attenuate the subjective effects of smoked cocaine in humans
    A S Ward
    Division on Substance Abuse, New York State Psychiatric Institute, NY 10032, USA
    Behav Pharmacol 10:523-9. 1999
    ..These data are concordant with findings in non-human primates, but contrast with findings in laboratory rodents, thus underscoring the importance of validation of rodent models with laboratory studies in humans...
  10. ncbi request reprint Sensitive and selective liquid chromatographic assay of memantine in plasma with fluorescence detection after pre-column derivatization
    R F Suckow
    Analytical Psychopharmacology Laboratory, New York State Psychiatric Institute, NY 10032, USA
    J Chromatogr B Biomed Sci Appl 729:217-24. 1999
    ..The limit of quantitation was 3 ng/ml, and no major antidepressant, neuroleptic or their respective metabolites interfered with the quantitation of memantine. This method could also be applied to the quantitation of amantadine...
  11. ncbi request reprint Choice between money and intranasal heroin in morphine-maintained humans
    S D Comer
    Division on Substance Abuse, New York State Psychiatric Institute, New York, USA
    Behav Pharmacol 8:677-90. 1997
    ..n. heroin self-administration can be modified by the availability of an alternative reinforcer (i.e. money); and (3) that self-reported drug effects can be differentiated from drug self-administration...
  12. ncbi request reprint Using buprenorphine to facilitate entry into residential therapeutic community rehabilitation
    Eric D Collins
    Department of Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Subst Abuse Treat 32:167-75. 2007
    ..The findings suggest the potential for buprenorphine to serve as a bridge, improving the viability of long-term residential treatment for managing opioid dependence...
  13. ncbi request reprint Memantine increases cardiovascular but not behavioral effects of cocaine in methadone-maintained humans
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Pharmacol Biochem Behav 83:47-55. 2006
    ..Taken together, these findings corroborate earlier data suggesting that this dose of memantine will not be helpful in the pharmacotherapy of cocaine abuse...
  14. ncbi request reprint Smoked cocaine discrimination in humans: effects of gabapentin
    Margaret Haney
    Division on Substance Abuse, Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    Drug Alcohol Depend 80:53-61. 2005
    ..The results suggest gabapentin may not produce effects sufficiently robust to be clinically useful, at least at this dose regimen...
  15. ncbi request reprint Buprenorphine/naloxone reduces the reinforcing and subjective effects of heroin in heroin-dependent volunteers
    Sandra D Comer
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
    Psychopharmacology (Berl) 181:664-75. 2005
    ..Although buprenorphine is effective in treating opioid dependence, optimal maintenance doses of buprenorphine or the buprenorphine/naloxone combination have not yet been established...
  16. ncbi request reprint Smoked cocaine self-administration by humans is not reduced by large gabapentin maintenance doses
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 86:274-7. 2007
    ....
  17. ncbi request reprint Gabapentin maintenance decreases smoked cocaine-related subjective effects, but not self-administration by humans
    Carl L Hart
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Dr, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 73:279-87. 2004
    ....
  18. ncbi request reprint The effects of venlafaxine on the subjective, reinforcing, and cardiovascular effects of cocaine in opioid-dependent and non-opioid-dependent humans
    Richard W Foltin
    Division on Substance Abuse, New York State Psychiatric Institute and College of Physicians and Surgeons of Columbia University, New York 10032, USA
    Exp Clin Psychopharmacol 11:123-30. 2003
    ..Although the reduction in cocaine's effects was small, further studies using a longer venlafaxine maintenance period or a larger venlafaxine dose are warranted...
  19. ncbi request reprint The effects of escalating doses of smoked cocaine in humans
    Richard W Foltin
    Division on Substance Abuse, New York State Psychiatric Institute, New York, NY, USA
    Drug Alcohol Depend 70:149-57. 2003
    ..e., "binge", of cocaine use can increment the effects of cocaine, but administering the same cocaine dose maintains, but does not increment the effects of cocaine...
  20. ncbi request reprint Self-administration of intravenous buprenorphine and the buprenorphine/naloxone combination by recently detoxified heroin abusers
    Sandra D Comer
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    J Pharmacol Exp Ther 303:695-703. 2002
    ..These results demonstrate that both BUP and BUP/NX served as reinforcers under these conditions and that they may have similar abuse liability in recently detoxified individuals who abuse heroin...
  21. ncbi request reprint Intravenous buprenorphine self-administration by detoxified heroin abusers
    Sandra D Comer
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Pharmacol Exp Ther 301:266-76. 2002
    ..These results demonstrate that buprenorphine served as a reinforcer under these conditions, and that it may have abuse liability in nonopioid-dependent individuals who abuse heroin...
  22. ncbi request reprint Depot naltrexone: long-lasting antagonism of the effects of heroin in humans
    Sandra D Comer
    Division on Substance Abuse, New York State Psychiatric Institute and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Psychopharmacology (Berl) 159:351-60. 2002
    ..However, naltrexone is generally not well accepted by patients, and medication non-compliance is a difficult obstacle to treatment. A sustained-release form of naltrexone may improve compliance...
  23. ncbi request reprint The effects of acute pretreatment with high-dose memantine on the cardiovascular and behavioral effects of cocaine in humans
    Eric D Collins
    Division on Substance Abuse, New York State Psychiatric Institute, NY, USA
    Exp Clin Psychopharmacol 15:228-37. 2007
    ..However, memantine pretreatment did not alter the choice to self-administer cocaine. These data suggest that memantine pretreatment may not be helpful in the treatment of cocaine dependence...
  24. ncbi request reprint Should opioid analgesics be used in the management of chronic pain in opiate addicts?
    Eric D Collins
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Addict 12:93-100. 2003