Research Topics
| J ClaassenSummaryAffiliation: Columbia University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Nutritional support and brain tissue glucose metabolism in poor-grade SAH: a retrospective observational studyJ Michael Schmidt
Columbia University, Department of Neurology, Milstein Hospital, 177 Fort Washington, Suite 8 300, New York, NY 10032, USA
Crit Care 16:R15. 2012..We sought to determine the effect of nutritional support and insulin infusion therapy on serum and brain glucose levels and cerebral metabolic crisis after aneurysmal subarachnoid hemorrhage (SAH)...
Continuous electroencephalographic monitoring in neurocritical careJan Claassen
Division of Critical Care Neurology, Columbia University, Neurological Institute, Box NI 1, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 2:534-40. 2002..New technologic developments include continuous digital video EEG, automated seizure-detection software, and user-friendly online quantitative EEG analysis...
Detection of electrographic seizures with continuous EEG monitoring in critically ill patientsJ Claassen
Division of Critical Care Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, USA
Neurology 62:1743-8. 2004..To identify patients most likely to have seizures documented on continuous EEG (cEEG) monitoring and patients who require more prolonged cEEG to record the first seizure...
Commentary on the Article of C. Woertgen, O. W. Ullrich, R. D. Rothoerl, A. Brawanski: Comparison of the Claassen and Fisher CT classification scale to predict ischemia after aneurysmatic SAH. Zentralbl Neurochir 2003; 64: 104-108J Claassen
Division of Critical Care Neurology, Neurological Institute, Columbia University, New York, New York 10032, USA
Zentralbl Neurochir 65:95-6; discussion 97. 2004
Continuous EEG monitoring in patients with subarachnoid hemorrhageJan Claassen
Comprehensive Epilepsy Center, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
J Clin Neurophysiol 22:92-8. 2005..CEEG findings may lead to therapeutic (e.g., antiepileptic medication, hypertensive therapy, angioplasty) or additional diagnostic interventions such as angiography, CT or MRI...
Generalized convulsive status epilepticus after nontraumatic subarachnoid hemorrhage: the nationwide inpatient sampleJan Claassen
Division of Stroke and Critical Care Neurology and Comprehensive Epilepsy Center, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Neurosurgery 61:60-4; discussion 64-5. 2007..To identify the frequency of and impact on outcome of generalized convulsive status epilepticus (GCSE) among patients with nontraumatic subarachnoid hemorrhage (SAH)...
Rheumatoid leptomeningitis after heart transplantationJan Claassen
Division of Stroke and Critical Care Neurology, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA
Neurology 66:948-9. 2006
Prognostic significance of continuous EEG monitoring in patients with poor-grade subarachnoid hemorrhageJan Claassen
Division of Stroke and Critical Care Neurology, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
Neurocrit Care 4:103-12. 2006..The objective of this study was to determine if continuous electroencephalogram (cEEG) monitoring results are predictive of 3-month outcome in critically ill patients with SAH...
Quantitative continuous EEG for detecting delayed cerebral ischemia in patients with poor-grade subarachnoid hemorrhageJan Claassen
The Division of Stroke and Critical Care Neurology, Department of Neurology, Neurological Institute, Columbia University, New York, NY 10032, USA
Clin Neurophysiol 115:2699-710. 2004..The purpose of this study was to identify quantitative EEG (qEEG) parameters that are most sensitive and specific for the detection of DCI in stuporous or comatose SAH patients...
Electrographic seizures and periodic discharges after intracerebral hemorrhageJ Claassen
Division of Stroke and Critical Care Neurology, Comprehensive Epilepsy Center, Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA
Neurology 69:1356-65. 2007..To determine the frequency and significance of electrographic seizures and other EEG findings in patients with intracerebral hemorrhage (ICH)...
How I treat patients with EEG patterns on the ictal-interictal continuum in the neuro ICUJan Claassen
Division of Neurocritical Care and Comprehensive Epilepsy Center, Department of Neurology, Columbia University, Milstein Hospital Building, 177 Fort Washington Avenue, Milstein 8 Center, New York, NY 10032, USA
Neurocrit Care 11:437-44. 2009..Ultimately it will be most important to replace the dichotomy of ictal versus non-ictal patterns by differentiating between harmful and non-harmful patterns...
Effect of cisternal and ventricular blood on risk of delayed cerebral ischemia after subarachnoid hemorrhage: the Fisher scale revisitedJ Claassen
Department of Neurology, School of Public Health, Columbia University College of Physicians and Surgeons, New York, NY, USA
Stroke 32:2012-20. 2001..We propose a new SAH rating scale that accounts for the independent predictive value of subarachnoid and ventricular blood for DCI...
Predictors and clinical impact of epilepsy after subarachnoid hemorrhageJ Claassen
Division of Critical Care Neurology, The Comprehensive Epilepsy Center, Department of Neurology, College of Physicians and Surgeons, School of Public Health, Columbia University, New York, NY, USA
Neurology 60:208-14. 2003..Our findings indicate that focal pathology, rather than diffuse injury from hemorrhage, is the principal cause of epilepsy after SAH...
Fever after subarachnoid hemorrhage: risk factors and impact on outcomeA Fernandez
Neurological Intensive Care Unit, Division of Stroke and Critical Care, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
Neurology 68:1013-9. 2007..To identify risk factors for refractory fever after subarachnoid hemorrhage (SAH), and to determine the impact of temperature elevation on outcome...
Continuous EEG monitoring and midazolam infusion for refractory nonconvulsive status epilepticusJ Claassen
Department of Neurology, Division of Critical Care Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Neurology 57:1036-42. 2001..Titrating cIV-MDZ to burst suppression, more aggressive treatment with concurrent AED, or a longer period of initial treatment may reduce the high proportion of patients with RSE who relapse after cIV-MDZ is discontinued...
Intracranial multimodal monitoring for acute brain injury: a single institution review of current practicesR Morgan Stuart
Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Neurocrit Care 12:188-98. 2010..Here we review our experience in a consecutive series of acutely brain injured patients who underwent multimodality monitoring...
Effect of rebleeding on the course and incidence of vasospasm after subarachnoid hemorrhageA S Lord
Department of Neurology, Columbia University, New York, NY, USA
Neurology 78:31-7. 2012..Whereas numerous studies have demonstrated the risk factors associated with rebleeding, few data on complications of rebleeding, including its effect on the development of delayed cerebral ischemia (DCI), are available...
Global cerebral edema after subarachnoid hemorrhage: frequency, predictors, and impact on outcomeJan Claassen
Division of Critical Care Neurology, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Stroke 33:1225-32. 2002..Critical care management strategies that minimize edema formation after SAH may improve outcome...
Systemic glucose and brain energy metabolism after subarachnoid hemorrhageRaimund Helbok
Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 Center, 177 Fort Washington Ave, New York, NY 10032, USA
Neurocrit Care 12:317-23. 2010..We sought to determine if MC and LPR elevations after subarachnoid hemorrhage (SAH) are associated with acute reductions in serum glucose...
Impact of medical complications on outcome after subarachnoid hemorrhageKatja E Wartenberg
Clinical Neuropsychology, New York Presbyterian Hospital, and Stroke and Critical Care, Columbia University, New York, NY, USA
Crit Care Med 34:617-23; quiz 624. 2006..Critical care strategies directed at maintaining normothermia, normoglycemia, and prevention of anemia may improve outcome after SAH...
Continuous electroencephalographic monitoring in critically ill patients with central nervous system infectionsEmmanuel Carrera
Comprehensive Epilepsy Center, Columbia University Medical Center, 710 W 168th St, Box NI 135, New York, NY 10032, USA
Arch Neurol 65:1612-8. 2008..To determine the prevalence, predictors, and clinical significance of electrographic seizures (ESz) and other continuous electroencephalographic monitoring findings in critically ill patients with central nervous system infections...
Continuous electroencephalogram monitoring in the intensive care unitDaniel Friedman
Department of Neurology, Comprehensive Epilepsy Center, Columbia University, NewYork City, New York, USA
Anesth Analg 109:506-23. 2009..The exact role and cost-effectiveness of cEEG at the current time remains unclear, but we believe it has significant potential to improve neurologic outcomes in a variety of settings...
Cardiac arrhythmias after subarachnoid hemorrhage: risk factors and impact on outcomeJennifer A Frontera
Neurological Intensive Care Unit, Department of Neurosurgery, Mount Sinai School of Medicine, New York, NY 10029, USA
Cerebrovasc Dis 26:71-8. 2008..Serious cardiac arrhythmias have been described in approximately 5% of patients after subarachnoid hemorrhage (SAH). The aim of this study was to identify the frequency, risk factors and clinical impact of cardiac arrhythmia after SAH...
Nonconvulsive status epilepticus after subarachnoid hemorrhageLyle J Dennis
Division of Critical Care Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, 710 West 168th Street, New York, NY 10032, USA
Neurosurgery 51:1136-43; discussion 1144. 2002..Routine postoperative cEEG monitoring of patients with SAH who are at high risk for NCSE, allowing earlier diagnosis and treatment, offers the best chance of improving the outcomes for patients with this disorder...
Spontaneous hyperventilation and brain tissue hypoxia in patients with severe brain injuryEmmanuel Carrera
Department of Neurology, Division of Neurocritical Care, Columbia University Medical Center, 177 Fort Washington Avenue, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 81:793-7. 2010..Our aim was to determine whether spontaneous reduction in end-tidal CO(2) (EtCO(2)) was associated with an increased in brain tissue hypoxia (BTH)...
Hyperglycemia after SAH: predictors, associated complications, and impact on outcomeJennifer A Frontera
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Stroke 37:199-203. 2006..17 per mmol/L; 95% CI 1.07 to 1.28, P<0.001). CONCLUSIONS: Hyperglycemia after SAH is associated with serious hospital complications, increased intensive care unit length of stay, and an increased risk of death or severe disability...
Global and domain-specific cognitive impairment and outcome after subarachnoid hemorrhageS A Mayer
Division of Critical Care Neurology, School of Public Health, Columbia University, New York, NY, USA
Neurology 59:1750-8. 2002..Cognitive dysfunction is the most common form of neurologic impairment after subarachnoid hemorrhage (SAH)...
Intracortical electroencephalography in acute brain injuryAllen Waziri
Department of Neurological Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA
Ann Neurol 66:366-77. 2009..We hypothesized that bedside placement of an intracortical multicontact electrode would allow for improved monitoring of cortical potentials in critically ill neurological patients...
Quantitative analysis of hemorrhage volume for predicting delayed cerebral ischemia after subarachnoid hemorrhageSang Bae Ko
Department of Neurology, Columbia University College of Physicians and Surgeons, Milstein Hospital Building 8 Center, 177 Fort Washington Avenue, New York, NY 10032, USA
Stroke 42:669-74. 2011..Quantification of hemorrhage on digitized images may be a more accurate method for predicting DCI than qualitative scales...
Continuous EEG monitoring: is it ready for prime time?Pedro Kurtz
Division of Neurocritical Care, Columbia University, Milstein Hospital, New York, New York 10032, USA
Curr Opin Crit Care 15:99-109. 2009..Continuous electroencephalography (cEEG) is being used more frequently in intensive care units to detect epileptic activity and ischemia. This review analyzes clinical applications and limitations of cEEG as a routine neuromonitoring tool...
Seizures and CNS hemorrhage: spontaneous intracerebral and aneurysmal subarachnoid hemorrhageEmily Gilmore
Division of Critical Care Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Neurologist 16:165-75. 2010..The deleterious effects of seizures on brain recovering from a recent injury have to be weighed against the deleterious effects of antiepileptic medications when making decisions on prophylaxis and treatment...
Transcranial Doppler for predicting delayed cerebral ischemia after subarachnoid hemorrhageEmmanuel Carrera
Neurological Intensive Care Unit, Departments of Neurology and Neurosurgery, Columbia University, New York, New York 10032, USA
Neurosurgery 65:316-23; discussion 323-4. 2009..We sought to determine the prognostic utility of serial TCD examination after SAH...
Exacerbation of perihematomal edema and sterile meningitis with intraventricular administration of tissue plasminogen activator in patients with intracerebral hemorrhageAndrew F Ducruet
Department of Neurological Surgery, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Neurosurgery 66:648-55. 2010..However, recent experimental work has implicated tissue plasminogen activator (tPA) in the pathogenesis of cerebral edema...
The current state of treatment of status epilepticusLawrence J Hirsch
Comprehensive Epilepsy Center, Columbia University Neurological Institute, Box NI 135, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 2:345-56. 2002..This article reviews these issues, concentrating on recent advances and practical issues related to the clinical care of patients with status epilepticus...
Treatment of refractory status epilepticus with pentobarbital, propofol, or midazolam: a systematic reviewJan Claassen
Department of Neurology, Division of Critical Care Neurology, and The Comprehensive Epilepsy Center, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Epilepsia 43:146-53. 2002..A prospective randomized trial comparing different agents and titration goals for RSE with obligatory continuous EEG monitoring is needed...
Anemia is associated with metabolic distress and brain tissue hypoxia after subarachnoid hemorrhagePedro Kurtz
Division of Critical Care Neurology, Department of Neurology, Columbia University, Milstein Hospital 8 Center, New York, NY 10032, USA
Neurocrit Care 13:10-6. 2010..The objective of this study is to assess whether there is an association between anemia and metabolic distress or brain tissue hypoxia in patients with subarachnoid hemorrhage...
Cerebral inflammatory response and predictors of admission clinical grade after aneurysmal subarachnoid hemorrhageKhalid A Hanafy
Department of Neurology, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032, USA
J Clin Neurosci 17:22-5. 2010..Strategies for mitigating the inflammatory response to aneurysmal rupture in the hyper-acute setting may improve the admission clinical grade, which may in turn improve outcomes...
Clinical response to hypertensive hypervolemic therapy and outcome after subarachnoid hemorrhageJennifer A Frontera
Departments of Neurosurgery and Neurology, Neuroscience Intensive Care Unit, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1136, New York, NY 10029, USA
Neurosurgery 66:35-41; discussion 41. 2010..Hypertensive hypervolemic therapy is widely used to treat symptomatic vasospasm after subarachnoid hemorrhage. Few data exist to support a relationship between early clinical response and mortality or functional outcome...
Refractory status epilepticus: frequency, risk factors, and impact on outcomeStephan A Mayer
Division of Critical Care Neurology, Neurological Institute, 710 W 168th St, Unit 39, New York, NY 10032, USA
Arch Neurol 59:205-10. 2002..How often RSE occurs, risk factors that predispose to this condition, and the effect of failure to control seizures on clinical outcome are poorly defined...
Impact of induced normothermia on outcome after subarachnoid hemorrhage: a case-control studyNeeraj Badjatia
Department of Neurology, Division of Neurocritical Care, Columbia University College of Physicians and Surgeons, New York, New York, USA
Neurosurgery 66:696-700; discussion 700-1. 2010..We sought to explore the potential impact of induced normothermia using advanced fever control (AFC) methods on outcome after SAH...
Cerebral perfusion pressure thresholds for brain tissue hypoxia and metabolic crisis after poor-grade subarachnoid hemorrhageJ Michael Schmidt
Neurological Intensive Care Unit, Department of Neurology, Columbia University Medical Center, and Milstein Hospital, 177 Fort Washington, 8 300, New York, NY 10032, USA
Stroke 42:1351-6. 2011..To identify a minimally acceptable cerebral perfusion pressure threshold above which the risks of brain tissue hypoxia (BTH) and oxidative metabolic crisis are reduced for patients with subarachnoid hemorrhage (SAH)...
Risk factors for continued cigarette use after subarachnoid hemorrhageJennifer Ballard
Division of Critical Care Neurology, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Stroke 34:1859-63. 2003..Cigarette smoking is a risk factor for the formation and rupture of intracranial aneurysms. Few studies have examined predictors of resumption of cigarette smoking after a first episode of subarachnoid hemorrhage (SAH)...
Stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs): a common EEG phenomenon in the critically illLawrence J Hirsch
Comprehensive Epilepsy Center Critical Care Division, Department of Neurology, Columbia University, New York, New York 10032, USA
Epilepsia 45:109-23. 2004..To describe an underrecognized EEG phenomenon in critically ill patients undergoing continuous EEG monitoring (cEEG). We named these EEG patterns stimulus-induced rhythmic, periodic, or ictal discharges (SIRPIDs)...
Clinical trial of a novel surface cooling system for fever control in neurocritical care patientsStephan A Mayer
Neurological Intensive Care Unit, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
Crit Care Med 32:2508-15. 2004..To compare the efficacy of a novel water-circulating surface cooling system with conventional measures for treating fever in neuro-intensive care unit patients...
Predictors and clinical implications of shivering during therapeutic normothermiaNeeraj Badjatia
Department of Neurology, Columbia University College of Physicians and Surgeons, 710 W 168th Street, New York, NY 10032, USA
Neurocrit Care 6:186-91. 2007..Shivering during induced normothermia (IN) remains a therapeutic limitation. We investigated potential risk factors and clinical implications of shivering during IN...
Relationship between energy balance and complications after subarachnoid hemorrhageNeeraj Badjatia
Departments of Neurology, Neurosurgery, and Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, USA
JPEN J Parenter Enteral Nutr 34:64-9. 2010..Subarachnoid hemorrhage patients are hypermetabolic and at risk for developing medical complications. A relationship was hypothesized between energy balance and complications following subarachnoid hemorrhage...
Focal motor seizures induced by alerting stimuli in critically ill patientsLawrence J Hirsch
Department of Neurology, Comprehensive Epilepsy Center, Neurological Institute, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
Epilepsia 49:968-73. 2008....
Cerebrovascular reactivity and vasospasm after subarachnoid hemorrhage: a pilot studyJ A Frontera
Division of Stroke and Neurocritical Care, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 66:727-9. 2006..011). Abnormal CO2R preceded the onset of vasospasm in 7 of 9 patients. Abnormal standard TCD testing was not associated with vasospasm...
Convulsive status epilepticus after ischemic stroke and intracerebral hemorrhage: frequency, predictors, and impact on outcome in a large administrative datasetBrian T Bateman
Columbia Presbyterian Medical College for Physicians and Surgeons, Columbia University, New York, NY, USA
Neurocrit Care 7:187-93. 2007..We examined the occurrence of GCSE in acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) using a large discharge database...
Defining vasospasm after subarachnoid hemorrhage: what is the most clinically relevant definition?Jennifer A Frontera
Mount Sinai School of Medicine, Department of Neurosurgery, One Gustave Levy Place, Box 1136, New York, NY 10029, USA
Stroke 40:1963-8. 2009..Vasospasm is an important complication of subarachnoid hemorrhage, but is variably defined in the literature...
Prediction of symptomatic vasospasm after subarachnoid hemorrhage: the modified fisher scaleJennifer A Frontera
Department of Neurology, Neurological Intensive Care Unit, Columbia University, College of Physicians and Surgeons, New York, New York, USA
Neurosurgery 59:21-7; discussion 21-7. 2006..CONCLUSION: The modified Fisher scale, which accounts for thick cisternal and ventricular blood, predicts symptomatic vasospasm after subarachnoid hemorrhage more accurately than original Fisher scale...
Cerebrovascular carbon dioxide reactivity and delayed cerebral ischemia after subarachnoid hemorrhageEmmanuel Carrera
Division of Neurocritical Care, Department of Neurology, Columbia University Medical Center, New York, New York 10032, USA
Arch Neurol 67:434-9. 2010..To determine the predictors of impaired cerebrovascular reactivity (CVR) and the value of CVR in predicting delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH)...
Treatment of status epilepticus: a survey of neurologistsJan Claassen
Division of Critical Care Neurology, Department of Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, 710 West 168th Street, Unit 39, New York, NY 10032, USA
J Neurol Sci 211:37-41. 2003..There is no consensus for third-line or fourth-line treatment for RSE. The treatment of RSE needs to be studied in a large, prospective, randomized, multicenter trial...
Resuscitation and critical care of poor-grade subarachnoid hemorrhageRicardo J Komotar
Department of Neurological Surgery, Columbia University, New York, New York 10032, USA
Neurosurgery 64:397-410; discussion 410-1. 2009....
Continuous electroencephalography in the medical intensive care unitMauro Oddo
Department of Neurology, Division of Critical Care, Neurological Institute, Columbia University Medical Center, New York, New York, USA
Crit Care Med 37:2051-6. 2009..To examine predictors and the prognostic value of electrographic seizures (ESZs) and periodic epileptiform discharges (PEDs) in medical intensive care unit (MICU) patients without a primary acute neurologic condition...
Cerebral infarction associated with acute subarachnoid hemorrhageJ Michael Schmidt
Neurological Intensive Care Unit, Division of Stroke and Critical Care, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Neurocrit Care 7:10-7. 2007..The frequency, causes, and clinical impact of acute infarction associated with the primary hemorrhage are poorly understood...
Impact of nosocomial infectious complications after subarachnoid hemorrhageJennifer A Frontera
Department of Neurosurgery, Mount Sinai School of Medicine, New York, New York 10029, USA
Neurosurgery 62:80-7; discussion 87. 2008..The aim of this study is to quantify the prevalence, risk factors, and effect on the outcome of nosocomial infectious complications in patients with subarachnoid hemorrhage (SAH)...
Frequency and clinical impact of asymptomatic cerebral infarction due to vasospasm after subarachnoid hemorrhageJ Michael Schmidt
Neurological Intensive Care Unit, Division of Neurocritical Care, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Neurosurg 109:1052-9. 2008..The authors sought to determine frequency, risk factors, and impact on outcome of asymptomatic cerebral infarction due to vasospasm after subarachnoid hemorrhage (SAH)...
Transcranial Doppler ultrasound in the acute phase of aneurysmal subarachnoid hemorrhageEmmanuel Carrera
Departments of Neurology and Neurosurgery, Neurological Intensive Care Unit, Columbia University, New York, N Y, USA
Cerebrovasc Dis 27:579-84. 2009..Angiographic studies suggest that acute vasospasm within 48 h of aneurysmal subarachnoid hemorrhage (SAH) predicts symptomatic vasospasm. However, the value of transcranial Doppler within 48 h of SAH is unknown...
Predictors of functional disability and mortality after status epilepticusJ Claassen
Department of Neurology, Division of Critical Care Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 58:139-42. 2002..Increased length of hospitalization (OR = 1.04; 95% CI, 1.0 to 1.1) and acute symptomatic seizures (OR = 3.9; 95% CI, 1.0 to 14.7) were predictors of functional disability...
Effect of acute physiologic derangements on outcome after subarachnoid hemorrhageJan Claassen
Division of Critical Care Neurology, Department of Neurology, College of Physicians and Surgeons, New York, NY, USA
Crit Care Med 32:832-8. 2004..The SAH Physiologic Derangement Score may prove useful for rapidly quantifying the severity of important physiologic derangements in acute SAH...
Effect of mannitol on brain metabolism and tissue oxygenation in severe haemorrhagic strokeRaimund Helbok
Division of Neurocritical Care, Department of Neurology, Columbia University Medical Center, Milstein Hospital 8 300 Center, New York, NY 10032, USA
J Neurol Neurosurg Psychiatry 82:378-83. 2011..The authors examined if mannitol treatment of raised intracranial pressure will result in an improvement in brain metabolism together with the expected drop in intracranial pressure (ICP)...
Global cerebral edema and brain metabolism after subarachnoid hemorrhageRaimund Helbok
Division of Critical Care Neurology, Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
Stroke 42:1534-9. 2011..Global cerebral edema is common among patients with poor-grade subarachnoid hemorrhage and is associated with poor outcome. Currently no targeted therapy exists largely due to an incomplete understanding of the underlying mechanisms...
Hypertensive encephalopathy with prominent bulbar presentationJoshua Z Willey
Department of Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Cerebrovasc Dis 21:210-2. 2006
Initial misdiagnosis and outcome after subarachnoid hemorrhageRobert G Kowalski
Division of Stroke and Critical Care Neurology, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
JAMA 291:866-9. 2004..A low threshold for CT scanning of patients with mild symptoms that are suggestive of SAH may reduce the frequency of misdiagnosis...
Frequency and predictors of nonconvulsive seizures during continuous electroencephalographic monitoring in critically ill childrenNathalie Jette
Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
Arch Neurol 63:1750-5. 2006..To determine the incidence, predictors, and timing of nonconvulsive seizures (NCSz) during continuous electroencephalographic monitoring (cEEG) in critically ill children...
Predictors of cognitive dysfunction after subarachnoid hemorrhageKurt T Kreiter
Stroke 33:200-8. 2002..Treatment strategies aimed at reducing neurological injury related to generalized brain swelling, infarction, and clot-related hemotoxicity hold the best promise for improving cognitive outcomes after SAH...
