Michael Chang

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Telomerase is essential to alleviate pif1-induced replication stress at telomeres
    Michael Chang
    Department of Genetics, Columbia University Medical Center, New York, New York 10032, USA
    Genetics 183:779-91. 2009
  2. pmc Long telomeres are preferentially extended during recombination-mediated telomere maintenance
    Michael Chang
    Department of Genetics and Development, Columbia University Medical Center, New York, New York, USA
    Nat Struct Mol Biol 18:451-6. 2011
  3. pmc Telomere length homeostasis responds to changes in intracellular dNTP pools
    Amitabha Gupta
    Department of Cellular, Molecular and Biophysical Studies, Columbia University Medical Center, New York, NY 10032, USA
    Genetics 193:1095-105. 2013

Collaborators

Detail Information

Publications3

  1. pmc Telomerase is essential to alleviate pif1-induced replication stress at telomeres
    Michael Chang
    Department of Genetics, Columbia University Medical Center, New York, New York 10032, USA
    Genetics 183:779-91. 2009
    ..At chromosome ends, collapsed forks result in truncated telomeres that must be rapidly elongated by telomerase to maintain viability...
  2. pmc Long telomeres are preferentially extended during recombination-mediated telomere maintenance
    Michael Chang
    Department of Genetics and Development, Columbia University Medical Center, New York, New York, USA
    Nat Struct Mol Biol 18:451-6. 2011
    ..We speculate that telomere length may be important in determining whether cancer cells use telomerase or ALT to bypass replicative senescence...
  3. pmc Telomere length homeostasis responds to changes in intracellular dNTP pools
    Amitabha Gupta
    Department of Cellular, Molecular and Biophysical Studies, Columbia University Medical Center, New York, NY 10032, USA
    Genetics 193:1095-105. 2013
    ..Our findings are consistent with in vitro data showing dGTP-dependent stimulation of telomerase activity in multiple organisms and suggest that telomerase activity is modulated in vivo by dGTP levels...