C N Boozer
Affiliation: Columbia University
- VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fastingSeung Hahm
Fishberg Research Center for Neurobiology, Mount Sinai School of Medicine, New York, New York 10029, USA
J Neurosci 22:6929-38. 2002....
- Energy balance in early-stage Huntington diseaseAnn M Gaba
Department of Food and Nutrition Services, New York Presbyterian Hospital, New York, NY, USA
Am J Clin Nutr 81:1335-41. 2005..Huntington disease (HD) is a genetic neurologic disorder. Weight loss is common in HD and is related to progression of the disease, but the cause of weight loss remains unclear...
- Simmondsin for weight loss in ratsC N Boozer
Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital Center, New York 10025, USA
Int J Obes (Lond) 30:1143-8. 2006..To investigate the safety and efficacy for weight loss of simmondsin, a dietary supplement extracted from the seed of the jojoba plant (Simmondsia chinensis)...
- An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trialC N Boozer
Obesity Research Center, St Luke s Roosevelt Hospital Center and Department of Medicine, Columbia University College of Physicians and Surgeons, New York 10025, USA
Int J Obes Relat Metab Disord 25:316-24. 2001..To examine in overweight humans the short-term safety and efficacy for weight loss of an herbal supplement containing Ma Huang, Guarana and other ingredients...
- Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trialC N Boozer
New York Obesity Research Center, St Luke s Roosevelt Hospital and Columbia University, New York 10025, USA
Int J Obes Relat Metab Disord 26:593-604. 2002..To examine long-term safety and efficacy for weight loss of an herbal Ma Huang and Kola nut supplement (90/192 mg/day ephedrine alkaloids/caffeine)...
- High-fat diet feeding elevates skeletal muscle uncoupling protein 3 levels but not its activity in ratsC J Chou
Obesity Research Center, St Luke s Roosevelt Hospital Center and Columbia University College of Physicians and Surgeons, New York, New York, USA
Obes Res 9:313-9. 2001..The objective of this study is to test the impact of high-fat diet (HFD) feeding on skeletal muscle (SM) uncoupling protein 3 (UCP3) expression and its association with mitochondrial ion permeability and whole-body energy homeostasis...
- Resting energy expenditure-fat-free mass relationship: new insights provided by body composition modelingZ Wang
Obesity Research Center, St Luke s Roosevelt Hospital, College of Physicians and Surgeons, Columbia University, New York, New York 10025, USA
Am J Physiol Endocrinol Metab 279:E539-45. 2000....
- High-fat hypocaloric diet modifies carbohydrate utilization of obese rats during weight lossM C Cha
New York Obesity Research Center, St. Luke's-Roosevelt Hospital, New York 10025, USA
Am J Physiol Endocrinol Metab 280:E797-803. 2001..These data suggest that dietary fat content modifies whole body glucose oxidation and intra-abdominal adipocyte glucose uptake during weight loss...
- Resting energy expenditure: systematic organization and critique of prediction methodsZ Wang
Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
Obes Res 9:331-6. 2001....
- Sleeping metabolic rate in relation to body mass index and body compositionK Zhang
Institute of Human Nutrition, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, USA
Int J Obes Relat Metab Disord 26:376-83. 2002..Specifically to determine the relationship between changes in SMR and body weight, body mass index (BMI, kg/m(2)), and fat-free mass (FFM); and to compare resting metabolic rate (RMR) with SMR during different periods of sleep...
- Heterozygosity for Lep(ob) or Lep(rdb) affects body composition and leptin homeostasis in adult miceW K Chung
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York 10032, USA
Am J Physiol 274:R985-90. 1998..These results raise the possibility that human mutations that have even subtle effects on the leptin/leptin receptor system in either the homozygous or heterozygous state may have significant effects on adiposity...
- Assessment of human locomotion by using an insole measurement system and artificial neural networksKuan Zhang
Obesity Research Center, St Luke s Roosevelt Hospital Center, 1111 Amsterdam Avenue, Room 1017, New York, NY 10025, USA
J Biomech 38:2276-87. 2005..It provides an alternative tool to the use of a gait lab to quantitatively study locomotion with high accuracy via a small, light and portable device, and to do so under free-living conditions for the clinical applications...
- Coffee, diabetes, and weight controlJames A Greenberg
Department of Health and Nutrition Sciences, Brooklyn College, City University of New York, New York, NY 11210, USA
Am J Clin Nutr 84:682-93. 2006..However, the ability of decaffeinated coffee to achieve these effects is based on a limited number of studies, and the underlying biological mechanisms have yet to be elucidated...
- Neuronal deletion of Lepr elicits diabesity in mice without affecting cold tolerance or fertilityJulie E McMinn
Department of Pediatrics, Division of Molecular Genetics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Am J Physiol Endocrinol Metab 289:E403-11. 2005..However, fertility and cold tolerance remain intact unless hypothalamic LEPR deficiency is complete...
- Acute insulin-induced elevations of circulating leptin and feeding inhibition in lean but not obese ratsKimberly A Singh
Obesity Research Center, St. Luke's-Roosevelt Hospital, 1111 Amsterdam Avenue, New York, NY 10025, USA
Am J Physiol Regul Integr Comp Physiol 289:R373-R379. 2005..Our data suggest that elevations of leptin within the physiological range may contribute to short-term inhibition of food intake in rats and that this process may be stimulated by feeding-related insulin release...
- Improving energy expenditure estimation for physical activityKuan Zhang
NY Obesity Research Center, St Lukes Roosevelt Hospital and Institute of Human Nutrition, Department of Medicine, Columbia University, New York, NY 10025, USA
Med Sci Sports Exerc 36:883-9. 2004..An additional aim was to improve the accuracy of the estimation of energy expenditure of physical activity based on second-by-second information of type, onset, and duration of activity...
- Measurement of human daily physical activityKuan Zhang
New York Obesity Research Center, St Luke s Roosevelt Hospital New York, New York 10025, USA
Obes Res 11:33-40. 2003..To validate a new device, Intelligent Device for Energy Expenditure and Activity (IDEEA), for the measurement of duration, frequency, and intensity of various types of human physical activity (PA)...
- High-resolution magnetic resonance imaging tracks changes in organ and tissue mass in obese and aging ratsHaiying Tang
Obesity Research Center, St. Luke's-Roosevelt Hospital, New York 10025, USA
Am J Physiol Regul Integr Comp Physiol 282:R890-9. 2002..No differences were detected in organ weights using MRI and dissection measurements. Longitudinal MRI measurements made during the development of obesity and aging accurately represented changes in organ and tissue mass...
- Intentional weight loss reduces mortality rate in a rodent model of dietary obesityJoseph R Vasselli
New York Obesity Research Center, Columbia University, New York, NY, USA
Obes Res 13:693-702. 2005..002). Diet composition had no effect on life span (p = 0.52). DISCUSSION: Weight loss after the onset of obesity during adulthood leads to a substantial increase in longevity in rats...
- Adiponectin levels during low- and high-fat eucaloric diets in lean and obese womenEvan S Berk
Institute of Human Nutrition, Columbia University, New York, USA
Obes Res 13:1566-71. 2005....
- Metabolic inflexibility in substrate use is present in African-American but not Caucasian healthy, premenopausal, nondiabetic womenEvan S Berk
New York Obesity Research Center, St. Luke's-Roosevelt Hospital Center, 1111 Amsterdam Avenue, Department of Medicine, Babcock Building Room 1031, New York, NY 10025, USA
J Clin Endocrinol Metab 91:4099-106. 2006..CONCLUSION: The impaired substrate use observed in African-American women during these three studies demonstrates the existence of MI and may contribute to their greater prevalence of obesity and insulin resistance...
- Higher post-absorptive skeletal muscle LPL activity in African American vs. non-Hispanic White pre-menopausal womenEvan S Berk
New York Obesity Research Center, St Luke s Hospital, Columbia University, New York, New York, USA
Obesity (Silver Spring) 16:199-201. 2008..Higher post-absorptive post-heparin plasma lipoprotein lipase (LPL) activity has been reported in African Americans as compared to non-Hispanic whites but differences in tissue-specific LPL activity are unclear...
- Free-Living Physical Activity and Energy ExpenditureCarol Boozer; Fiscal Year: 2003..Finally, data from these studies will provide the basis for a future application to conduct a longitudinal, PA intervention study in this population. ..