Research Topics
| A S BombackSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Aldosterone breakthrough during aliskiren, valsartan, and combination (aliskiren + valsartan) therapyAndrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J Am Soc Hypertens 6:338-45. 2012..8 mm Hg in subjects without breakthrough. Aliskiren, alone or in combination with valsartan, did not reduce the incidence of aldosterone breakthrough in subjects with hypertension and proteinuria compared with conventional RAAS blockade...
Treatment of resistant glomerular diseases with adrenocorticotropic hormone gel: a prospective trialAndrew S Bomback
Division of Nephrology, Department of Medicine, Columbia University Medical Center, New York, NY, USA
Am J Nephrol 36:58-67. 2012..Adrenocorticotropic hormone (ACTH) has shown promising results in glomerular diseases resistant to conventional therapies, but the reported data have solely been from retrospective, observational studies...
Eculizumab for dense deposit disease and C3 glomerulonephritisAndrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York, USA
Clin J Am Soc Nephrol 7:748-56. 2012..Eculizumab, a monoclonal antibody that binds to C5 to prevent formation of the membrane attack complex, may prove beneficial...
Racial differences in kidney function among individuals with obesity and metabolic syndrome: results from the Kidney Early Evaluation Program (KEEP)Andrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, 622 W 168th Street, New York, NY 10032, USA
Am J Kidney Dis 55:S4-S14. 2010....
A new apolipoprotein E mutation, apoE Las Vegas, in a European-American with lipoprotein glomerulopathyAndrew S Bomback
Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
Nephrol Dial Transplant 25:3442-6. 2010..Whereas prior European-American patients with lipoprotein glomerulopathy were found to have the previously reported apoE Kyoto genotype, the patient presented here was found to have a novel mutation that we have named apoE Las Vegas...
Gestational diabetes mellitus alone in the absence of subsequent diabetes is associated with microalbuminuria: results from the Kidney Early Evaluation Program (KEEP)Andrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, New York, USA
Diabetes Care 33:2586-91. 2010..Overt diabetes is a risk factor for development of chronic kidney disease (CKD), but GDM alone, without subsequent development of overt diabetes, may also pose a risk for CKD...
ANCA-associated glomerulonephritis in the very elderlyAndrew S Bomback
Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Kidney Int 79:757-64. 2011..3). However, when follow-up was extended beyond 2 years, immunosuppression was associated with a lower risk of death (HR 0.33, 95% CI 0.11-0.97) and death or ESRD (HR 0.16, 95% CI 0.06-0.42) in multivariable models...
Treatment of nephrotic syndrome with adrenocorticotropic hormone (ACTH) gelAndrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Drug Des Devel Ther 5:147-53. 2011..We therefore investigated the use of ACTH gel for nephrotic syndrome in the United States...
Treatment of nephrotic syndrome with adrenocorticotropic hormone (ACTH)Andrew S Bomback
Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Discov Med 12:91-6. 2011..We discuss a number of possible mechanisms for ACTH's beneficial effects on the inflammation and injury that occurs in nephrotic syndrome...
Sugar-sweetened soda consumption, hyperuricemia, and kidney diseaseAndrew S Bomback
Division of Nephrology, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Kidney Int 77:609-16. 2010..Thus our study shows that high consumption of sugar-sweetened soda was associated with prevalent but not incident hyperuricemia and chronic kidney disease...
Low-dose spironolactone, added to long-term ACE inhibitor therapy, reduces blood pressure and urinary albumin excretion in obese patients with hypertensive target organ damageA S Bomback
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, 622 West 168th Street, PH 4 124, New York, NY 10032, USA
Clin Nephrol 72:449-56. 2009..This may be particularly true for hypertensive patients with obesity, a condition often associated with elevated aldosterone levels...
Disordered aldosterone-volume relationship in end-stage kidney diseaseAndrew S Bomback
Columbia University College of Physicians and Surgeons, Department of Medicine, Division of Nephrology, New York, NY, USA
J Renin Angiotensin Aldosterone Syst 10:230-6. 2009..Sodium loading, and subsequent volume expansion, suppresses aldosterone levels in individuals with normal renal function. We hypothesised that loss of renal function impairs this volume-aldosterone relationship...
Sugar-sweetened beverage consumption and the progression of chronic kidney disease in the Multi-Ethnic Study of Atherosclerosis (MESA)Andrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University Medical Center, New York, NY 10032, USA
Am J Clin Nutr 90:1172-8. 2009....
Dual blockade of the renin-angiotensin-aldosterone system: beyond the ACE inhibitor and angiotensin-II receptor blocker combinationAndrew S Bomback
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, New York, USA
Am J Hypertens 22:1032-40. 2009..This review examines what is presently known about ACEI/ARB combination therapy and explores alternative combination strategies that include DRIs and mineralocorticoid receptor blockers (MRBs)...
Interaction of aldosterone and extracellular volume in the pathogenesis of obesity-associated kidney disease: a narrative reviewAndrew S Bomback
UNC Kidney Center, Department of Medicine, Division of Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7155, USA
Am J Nephrol 30:140-6. 2009....
Prevalence of CKD and comorbid illness in elderly patients in the United States: results from the Kidney Early Evaluation Program (KEEP)Lesley A Stevens
Division of Nephrology, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
Am J Kidney Dis 55:S23-33. 2010..In all 3 data sources, we also explored comorbid conditions and CKD-related complications...
Renal transplantation in familial dysautonomia: report of two cases and review of the literatureYelena Rekhtman
Department of Medicine, Division of Nephrology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Clin J Am Soc Nephrol 5:1676-80. 2010..Transplant was performed after 3 months on intermittent hemodialysis (HD) in the first case and after 1 month on twice-weekly continuous veno-venous hemodialysis (CVVHD) in the second case...
Change in proteinuria after adding aldosterone blockers to ACE inhibitors or angiotensin receptor blockers in CKD: a systematic reviewAndrew S Bomback
Department of Medicine, Division of Nephrology and Hypertension, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Kidney Dis 51:199-211. 2008....
Of snakes and men: the evolution of ACE inhibitorsAndrew S Bomback
Department of Medicine, University of North Carolina School of Medicine, Kidney Center, Chapel Hill, North Carolina, 27599-7155, USA
J Renin Angiotensin Aldosterone Syst 8:1-2. 2007
Screening for kidney disease in vascular patients: SCreening for Occult REnal Disease (SCORED) experienceHeejung Bang
Division of Biostatistics and Epidemiology, Department of Public Health, Weill Medical College of Cornell University, New York, NY, USA
Nephrol Dial Transplant 24:2452-7. 2009..Recently, CKD screening in individuals with cardiovascular disease (CVD) has been emphasized. We therefore evaluated the SCORED model in CVD patients in order to better understand the implications of CKD screening in this population...
Rituximab therapy for membranous nephropathy: a systematic reviewAndrew S Bomback
Department of Medicine, Division of Nephrology and Hypertension, University of North Carolina Kidney Center, Chapel Hill, North Carolina 27599 7155, USA
Clin J Am Soc Nephrol 4:734-44. 2009..The treatment of membranous nephropathy (MN) remains controversial. Rituximab, which selectively targets B cells, has emerged as a possible alternative treatment option with limited toxicity...
A simple algorithm to predict incident kidney diseaseAbhijit V Kshirsagar
Division of Nephrology and Hypertension, Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7155, USA
Arch Intern Med 168:2466-73. 2008..Despite the growing burden of chronic kidney disease (CKD), there are no algorithms (to our knowledge) to quantify the effect of concurrent risk factors on the development of incident disease...
Jack London's "chronic interstitial nephritis". A historical differential diagnosisAndrew S Bomback
Department of Medicine, Division of Nephrology and Hypertension, University of North Carolina School of Medicine, Chapel Hill, USA
Pharos Alpha Omega Alpha Honor Med Soc 71:26-30. 2008
