Maura Boldrini

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression
    Maura Boldrini
    Department of Psychiatry, Columbia University, New York, NY, USA
    Neuropsychopharmacology 38:1068-77. 2013
  2. pmc Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression
    Maura Boldrini
    Department of Psychiatry, Columbia University, Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 72:562-71. 2012
  3. pmc Antidepressants increase neural progenitor cells in the human hippocampus
    Maura Boldrini
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 42, New York, NY 10032, USA
    Neuropsychopharmacology 34:2376-89. 2009
  4. pmc Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides
    Maura Boldrini
    Department of Psychiatry, Division of Neuroscience, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, P O Box 42, New York, NY 10032, USA
    J Psychiatr Res 42:433-42. 2008
  5. ncbi request reprint More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides
    Maura Boldrini
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    Brain Res 1041:19-28. 2005

Detail Information

Publications5

  1. pmc Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression
    Maura Boldrini
    Department of Psychiatry, Columbia University, New York, NY, USA
    Neuropsychopharmacology 38:1068-77. 2013
    ..This may contribute to a smaller hippocampus and is potentially reversed by SSRIs. Postmortem studies are correlative and animal studies are needed to test implied causal relationships...
  2. pmc Hippocampal angiogenesis and progenitor cell proliferation are increased with antidepressant use in major depression
    Maura Boldrini
    Department of Psychiatry, Columbia University, Division of Molecular Imaging and Neuropathology, New York State Psychiatric Institute, New York, New York 10032, USA
    Biol Psychiatry 72:562-71. 2012
    ..We hypothesized that, in major depressive disorder (MDD), antidepressants increase neural progenitor cells (NPCs) and capillaries in the human DG...
  3. pmc Antidepressants increase neural progenitor cells in the human hippocampus
    Maura Boldrini
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, Box 42, New York, NY 10032, USA
    Neuropsychopharmacology 34:2376-89. 2009
    ..009). Antidepressants increase NPC number in the anterior human DG. Whether this finding is critical or necessary for the antidepressants effect remains to be determined...
  4. pmc Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides
    Maura Boldrini
    Department of Psychiatry, Division of Neuroscience, Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, 1051 Riverside Drive, P O Box 42, New York, NY 10032, USA
    J Psychiatr Res 42:433-42. 2008
    ..More autoreceptor binding in rostral DRN might contribute to deficient serotonin release in ventromedial prefrontal cortex by lower neuronal firing...
  5. ncbi request reprint More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides
    Maura Boldrini
    Department of Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA
    Brain Res 1041:19-28. 2005
    ..More TPH may be an upregulatory homeostatic response to impaired serotonin release or less autoreceptor activation. Alternatively, the serotonin impairment in suicide may be due to hypofunctional serotonin-synthesizing enzyme...

Research Grants3

  1. Effect of Major Depression and antidepressants on human neurogenesis
    Maura Boldrini; Fiscal Year: 2009
    ..We propose to examine neurogenesis in MDD patients, with and without ADT, compared to normal healthy controls, evaluating whether neurogenesis is reduced in MDD and restored by ADT. ..
  2. Effect of Major Depression and antidepressants on human neurogenesis
    Maura Boldrini; Fiscal Year: 2010
    ..We propose to examine neurogenesis in MDD patients, with and without ADT, compared to normal healthy controls, evaluating whether neurogenesis is reduced in MDD and restored by ADT. ..
  3. Effect of Major Depression and antidepressants on human neurogenesis
    Maura Boldrini; Fiscal Year: 2011
    ..We propose to examine neurogenesis in MDD patients, with and without ADT, compared to normal healthy controls, evaluating whether neurogenesis is reduced in MDD and restored by ADT. ..