Research Topics
| Carl W BazilSummaryAffiliation: Columbia University Country: USA Publications
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Detail Information
Publications
First seizure: do multiple seizures predict recurrence?Carl W Bazil
Neurology 67:927. 2006
Health-related quality of life over time since resective epilepsy surgerySusan S Spencer
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
Ann Neurol 62:327-34. 2007..Health-related quality of life (HRQOL) improves after resective epilepsy surgery, but data are limited to short follow-up in mostly retrospective reports, with minimal consideration of other potential factors that might influence HRQOL...
Pregabalin increases slow-wave sleep and may improve attention in patients with partial epilepsy and insomniaC W Bazil
Columbia University, New York, NY 10032, USA
Epilepsy Behav 23:422-5. 2012..This study was performed to look at the effects of pregabalin, an anticonvulsant known to increase sleep depth and decrease arousals, in patients with insomnia and well-controlled epilepsy...
Nocturnal seizures and the effects of anticonvulsants on sleepCarl W Bazil
The Neurological Institute, Columbia University, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 8:149-54. 2008..Therefore, awareness of the implications of sleep disorders and anticonvulsants is critical for the optimal care of patients with epilepsy...
Effects of antiepileptic drugs on sleep structure : are all drugs equal?Carl W Bazil
Columbia Comprehensive Epilepsy Center, New York, New York 10032, USA
CNS Drugs 17:719-28. 2003..But because AEDs have independent effects on sleep quality, the choice of an appropriate agent not only determines whether seizures are completely controlled but also whether the patient performs optimally on a daily basis...
Sleep structure in patients with psychogenic nonepileptic seizuresCarl W Bazil
Comprehensive Epilepsy Center, The Neurological Institute, Columbia University, 710 West 168th Street, New York, NY 10032, USA
Epilepsy Behav 4:395-8. 2003..REM latency was less in PNES patients although not significantly. The study suggests that patients with PNES have a sleep architecture similar to that found in major depression, known to be associated with increased REM sleep...
Epilepsy and sleep disturbanceCarl W Bazil
The Neurological Institute, 710 West 168th Street, New York, NY 10032, USA
Epilepsy Behav 4:S39-45. 2003..Sleep should be proactively evaluated, and sleep disturbances should be treated as part of the total care of patients with epilepsy...
Seizures in the life and works of Edgar Allan PoeC W Bazil
Comprehensive Epilepsy Center, Columbia Presbyterian Medical Center, New York, NY 10032, USA
Arch Neurol 56:740-3. 1999..Poe was able to use creative genius and experiences from illness to create memorable tales and poignant poems...
Sleep disturbances in epilepsy patientsCarl W Bazil
Comprehensive Epilepsy Center, Columbia University, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 5:297-8. 2005
Anticonvulsant drug or neuromodulator? The growing case for anticonvulsant uses beyond epilepsyCarl W Bazil
Neurological Institute of New York, Columbia University College of Physicians and Surgeons, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 4:305-7. 2004..Epilepsy drugs were often used for other disorders before their effectiveness in epilepsy was fully appreciated, and the efficacy of newer antiepileptic drugs for conditions other than epilepsy is now being studied...
Comprehensive care of the epilepsy patient--control, comorbidity, and costCarl W Bazil
Comprehensive Epilepsy Center, Columbia University, New York, New York 10032, USA
Epilepsia 45:3-12. 2004....
Gabapentin improves sleep in the presence of alcoholCarl W Bazil
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Clin Sleep Med 1:284-7. 2005..To evaluate the ability of a single dose of gabapentin to improve sleep disruption caused by alcohol consumption...
Sleep-related epilepsyCarl W Bazil
Comprehensive Epilepsy Center, Columbia University, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 3:167-72. 2003....
Effects of levetiracetam on sleep in normal volunteersCarl W Bazil
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Epilepsy Behav 7:539-42. 2005..Levetiracetam is a novel anticonvulsant effective for the treatment of partial seizures. We studied the effects of levetiracetam (LEV) on sleep using polysomnography in normal subjects...
Reduction of rapid eye movement sleep by diurnal and nocturnal seizures in temporal lobe epilepsyC W Bazil
Department of Neurology, Comprehensive Epilepsy Center, Columbia Presbyterian Medical Center, New York, NY 10032, USA
Arch Neurol 57:363-8. 2000..A possible explanation is that seizures, even when occurring during the day, disrupt sleep the following night...
Levetiracetam may be more effective for late-onset partial epilepsyCarl W Bazil
Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York, NY 10032, USA
Arch Neurol 59:1905-8. 2002..Clinical experience suggests that certain individuals will respond to a given agent while others with the same seizure type will not...
Effects of sleep on the postictal stateCarl W Bazil
Columbia Comprehensive Epilepsy Center, New York, NY 10032, USA
Epilepsy Behav 19:146-50. 2010..Awareness of the various manifestations of sleep disorders, seizures, and postictal phenomena during sleep is critical to optimal diagnosis and treatment of patients with epilepsy...
New antiepileptic drugsC W Bazil
Comprehensive Epilepsy Center, Columbia University College of Physicians and Surgeons, 710 West 168th Street, New York, NY 10032, USA
Curr Neurol Neurosci Rep 1:369-75. 2001..Adverse effects can also help distinguish between agents. Familiarity with this latest information will help clinicians make the best choice for each of their patients with epilepsy...
Sleep and epilepsyC W Bazil
Comprehensive Epilepsy Center, The Neurological Institute of Columbia University, New York, NY 10032, USA
Curr Opin Neurol 13:171-5. 2000..Seizures, in turn, can disrupt sleep structure, particularly rapid-eye-movement sleep. An understanding of these relationships is important in seizure control and in maximizing the quality of life for patients with epilepsy...
Patients with intractable epilepsy have low melatonin, which increases following seizuresC W Bazil
Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
Neurology 55:1746-8. 2000..Cortisol also increased following seizures. Patients with intractable epilepsy have low baseline melatonin levels that increase dramatically following seizures...
Comparative effectiveness of 10 antiepileptic drugs in older adults with epilepsyHiba Arif
Comprehensive Epilepsy Center, Columbia University, Neurological Institute, 710 W 168th St, New York, NY 10032, USA
Arch Neurol 67:408-15. 2010..To compare the effectiveness of antiepileptic drugs (AEDs) for use in older adults with epilepsy...
Sleep and epilepsyCarl W Bazil
The Neurological Institute, New York, New York 10032, USA
Semin Neurol 22:321-7. 2002..Finally, most patients with epilepsy are treated with anticonvulsant drugs, some of which can have adverse (or beneficial) effects on sleep...
Effects of antiepileptic drugs on sleep architecture: a pilot studyBenjamin Legros
Comprehensive Epilepsy Center, Columbia-Presbyterian Medical Center, New York, NY 10032, USA
Sleep Med 4:51-5. 2003..CONCLUSIONS: AEDs have differing effects on sleep structure, which can be beneficial or detrimental. Consideration of these potential effects is important in maintaining optimal sleep in patients with epilepsy...
Effect of age and comedication on levetiracetam pharmacokinetics and tolerabilityLawrence J Hirsch
Comprehensive Epilepsy Center, Department of Neurology, Neurological Institute, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
Epilepsia 48:1351-9. 2007..To compare pharmacokinetics and tolerability of levetiracetam (LEV) in older versus younger adults...
Cross-sensitivity of skin rashes with antiepileptic drug useL J Hirsch
Associate Clinical Comprehensive Epilepsy Center, Columbia University, Neurological Institute, New York, NY 10032, USA
Neurology 71:1527-34. 2008..To determine rates of cross-sensitivity of rash among commonly used antiepileptic drugs (AEDs) in patients with epilepsy...
ECT in the treatment of status epilepticusS H Lisanby
Department of Biological Psychiatry, New York State Psychiatric Institute, New York 10032 2695, USA
J ECT 17:210-5. 2001..Owing to its potent anticonvulsant actions, electroconvulsive therapy (ECT) has been proposed as an intervention for treatment-resistant seizure disorders...
Correlating lamotrigine serum concentrations with tolerability in patients with epilepsyL J Hirsch
Comprehensive Epilepsy Center, Department of Neurology, Mailman School of Public Health, Columbia University, 710 W 168 St, Box NI 135, New York, NY 10032, USA
Neurology 63:1022-6. 2004..To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy...
Epilepsy and common comorbidities: improving the outpatient epilepsy encounterFrank G Gilliam
Department of Neurology, Neurological Institute, Columbia University, New York, NY 10032, USA
Epileptic Disord 7:S27-33. 2005..Management strategies employed in the outpatient clinic to maximize overall health outcomes should include screening and treatment for the commonly coexistent conditions in persons with epilepsy...
Nocturnal seizuresCarl W Bazil
Columbia Comprehensive Epilepsy Center, New York, New York, USA
Semin Neurol 24:293-300. 2004....
Update on anticonvulsant drugsDerek J Chong
Columbia Comprehensive Epilepsy Center, Department of Neurology, Columbia University, 710 West 168th Street, 7th Floor, New York, NY 10032, USA
Curr Neurol Neurosci Rep 10:308-18. 2010..This review discusses these issues and provides a current overview for the medical management of epilepsy...
Comparison and predictors of rash associated with 15 antiepileptic drugsH Arif
Comprehensive Epilepsy Center, Department of Neurology, Columbia University, New York, NY 10032, USA
Neurology 68:1701-9. 2007..To determine predictors and relative incidence of antiepileptic drug (AED)-related rash in patients taking all common AEDs...
Health care costs decline after successful epilepsy surgeryJ T Langfitt
Department of Neurology, University of Rochester, Rochester, NY 14642, USA
Neurology 68:1290-8. 2007..There is little information about how health care costs are affected by evaluation and surgery...
Occurrence of seizure clusters and status epilepticus during inpatient video-EEG monitoringA B Rose
Columbia College of Physicians and Surgeons, New York, NY, USA
Neurology 60:975-8. 2003..Intensive monitoring with drug withdrawal must be performed in a highly supervised, hospitalized setting. Inpatient video-EEG monitoring is efficient, with recording of the first epileptic or nonepileptic events in 2 days or less...
Quantitative and qualitative analysis of ambulatory electroencephalography during mild traumatic brain injuryJeremy J Moeller
Columbia Comprehensive Medical Center, New York, NY 10032, USA
Arch Neurol 68:1595-8. 2011....
Clinical pharmacology of antiepileptic drugsCarl W Bazil
The Comprehensive Epilepsy Center, The Neurological Institute of New York, Columbia University, New York, New York 10032, USA
Clin Neuropharmacol 26:38-52. 2003
Interrater reliability among epilepsy centers: multicenter study of epilepsy surgerySheryl R Haut
Comprehensive Epilepsy Management Center and Departments of Neurology and Pediatrics of the Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, New York, USA
Epilepsia 43:1396-401. 2002..We believe that this study demonstrates the feasibility of implementing multicenter protocols for neurologic management, especially those involving localization, as well as protocols combining study results with clinical decision making...
New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsMichael A Rogawski
Department of Neurology, School of Medicine, University of California, Davis, 4860 Y Street, Suite 3700, Sacramento, CA 95817, USA
Curr Neurol Neurosci Rep 8:345-52. 2008..Functionally, all of the new targets modulate neurotransmitter output at synapses, focusing attention on presynaptic terminals as critical sites of action for AEDs...
Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter studyS S Spencer
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
Neurology 65:912-8. 2005..In a seven-center prospective observational study of resective epilepsy surgery, the authors examined probability and predictors of entering 2-year remission and the risk of subsequent relapse...
Initial outcomes in the Multicenter Study of Epilepsy SurgeryS S Spencer
Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
Neurology 61:1680-5. 2003..To obtain prospective data regarding seizures, anxiety, depression, and quality of life (QOL) outcomes after resective epilepsy surgery...
Distribution of partial seizures during the sleep--wake cycle: differences by seizure onset siteS T Herman
Department of Neurology, State University of New York, Brooklyn, USA
Neurology 56:1453-9. 2001..To evaluate the effects of sleep on partial seizures arising from various brain regions...
Changes in depression and anxiety after resective surgery for epilepsyO Devinsky
New York University School of Medicine, New York, NY, USA
Neurology 65:1744-9. 2005..To determine changes in depression and anxiety after resective surgery...
Improved quality of life in patients with partial seizures after conversion to oxcarbazepine monotherapyRajesh C Sachdeo
Princeton Medical Center, Princeton, NJ 08540, USA
Epilepsy Behav 9:457-63. 2006..Quality of life (QOL) was assessed in patients who switched to oxcarbazepine monotherapy because of the lack of efficacy or poor tolerability of their current antiepileptic drug (AED)...
Sleep disturbances reported by refractory partial-onset epilepsy patients receiving polytherapyXiao Xu
Covance Market Access Services, Gaithersburg, Maryland 20878, USA
Epilepsia 47:1176-83. 2006..Although sleep disturbances are common in epilepsy, few studies examined the prevalence and impact of sleep disturbance in epilepsy patients. This study investigates these in a cross-sectional survey...
The multicenter study of epilepsy surgery: recruitment and selection for surgeryAnne T Berg
BIOS NIU, DeKalb, Illinois 60115, USA
Epilepsia 44:1425-33. 2003..Such information is necessary for providing the epidemiologic and clinical context in which epilepsy surgery is currently performed in the United States and in other developed countries...
Many options for epilepsy: comparisons of first- and second-generation AEDsCarl W Bazil
Curr Neurol Neurosci Rep 8:323-4. 2008
Employment outcomes following resective epilepsy surgeryPeter S Chin
Robert Wood Johnson Clinical Scholars Program, Department of Medicine, University of California Los Angeles and the Greater Los Angeles VA Health Care System, Los Angeles, California 90095 1769, USA
Epilepsia 48:2253-7. 2007..Analyze determinates of employment changes from before to 2 years after surgery in refractory focal epilepsy patients...
