Graham Barr

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Does paracetamol cause asthma in children? Time to remove the guesswork
    R Graham Barr
    Columbia University Medical Center, New York, NY 10032, USA
    Lancet 372:1011-2. 2008
  2. ncbi request reprint Emphysema Predicts Hospitalisation and Incident Airflow Obstruction among Older Smokers: A Prospective Cohort Study
    David A McAllister
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
    PLoS ONE 9:e93221. 2014
  3. pmc The association of systemic microvascular changes with lung function and lung density: a cross-sectional study
    Bianca Harris
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e50224. 2012
  4. ncbi request reprint Pulmonary hyperinflation and left ventricular mass: the Multi-Ethnic Study of Atherosclerosis COPD Study
    Benjamin M Smith
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Circulation 127:1503-11, 1511e1-6. 2013
  5. pmc Subclinical atherosclerosis, airflow obstruction and emphysema: the MESA Lung Study
    R G Barr
    Dept of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Eur Respir J 39:846-54. 2012
  6. pmc The clinical features of the overlap between COPD and asthma
    Megan Hardin
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Respir Res 12:127. 2011
  7. pmc Longitudinal association of body mass index with lung function: the CARDIA study
    Bharat Thyagarajan
    Dept of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
    Respir Res 9:31. 2008
  8. pmc Impact of DOTS expansion on tuberculosis related outcomes and costs in Haiti
    Vary Jacquet
    National Tuberculosis Control Programme, Port au Prince, Haiti
    BMC Public Health 6:209. 2006
  9. pmc Percent emphysema, airflow obstruction, and impaired left ventricular filling
    R Graham Barr
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    N Engl J Med 362:217-27. 2010
  10. ncbi request reprint Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Med 118:1415. 2005

Detail Information

Publications62

  1. ncbi request reprint Does paracetamol cause asthma in children? Time to remove the guesswork
    R Graham Barr
    Columbia University Medical Center, New York, NY 10032, USA
    Lancet 372:1011-2. 2008
  2. ncbi request reprint Emphysema Predicts Hospitalisation and Incident Airflow Obstruction among Older Smokers: A Prospective Cohort Study
    David A McAllister
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
    PLoS ONE 9:e93221. 2014
    ..Emphysema on CT is common in older smokers. We hypothesised that emphysema on CT predicts acute episodes of care for chronic lower respiratory disease among older smokers...
  3. pmc The association of systemic microvascular changes with lung function and lung density: a cross-sectional study
    Bianca Harris
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, United States of America
    PLoS ONE 7:e50224. 2012
    ....
  4. ncbi request reprint Pulmonary hyperinflation and left ventricular mass: the Multi-Ethnic Study of Atherosclerosis COPD Study
    Benjamin M Smith
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Circulation 127:1503-11, 1511e1-6. 2013
    ..We therefore hypothesized that residual lung volume in COPD would be associated with greater LV mass...
  5. pmc Subclinical atherosclerosis, airflow obstruction and emphysema: the MESA Lung Study
    R G Barr
    Dept of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Eur Respir J 39:846-54. 2012
    ..An obstructive pattern of spirometry and emphysema were associated distinctly and independently with subclinical atherosclerosis in the carotid arteries and peripheral circulation, respectively, and were not independently related to CAC...
  6. pmc The clinical features of the overlap between COPD and asthma
    Megan Hardin
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Respir Res 12:127. 2011
    ..The coexistence of COPD and asthma is widely recognized but has not been well described. This study characterizes clinical features, spirometry, and chest CT scans of smoking subjects with both COPD and asthma...
  7. pmc Longitudinal association of body mass index with lung function: the CARDIA study
    Bharat Thyagarajan
    Dept of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
    Respir Res 9:31. 2008
    ..Lung function at the end of life depends on its peak and subsequent decline. Because obesity is epidemic in young adulthood, we quantified age-related changes in lung function relative to body mass index (BMI)...
  8. pmc Impact of DOTS expansion on tuberculosis related outcomes and costs in Haiti
    Vary Jacquet
    National Tuberculosis Control Programme, Port au Prince, Haiti
    BMC Public Health 6:209. 2006
    ..We estimated potential costs and benefits of DOTS expansion in Haiti from the government, and societal perspectives...
  9. pmc Percent emphysema, airflow obstruction, and impaired left ventricular filling
    R Graham Barr
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    N Engl J Med 362:217-27. 2010
    ....
  10. ncbi request reprint Physician and patient perceptions in COPD: the COPD Resource Network Needs Assessment Survey
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Med 118:1415. 2005
    ..National data are lacking on patient and physician perceptions of and patterns of care for COPD...
  11. pmc Tiotropium for stable chronic obstructive pulmonary disease: A meta-analysis
    R G Barr
    Division of General Medicine, PH 9 East Room 105, Columbia University Medical Centre, 630 West 168th Street, New York, NY 10032, USA
    Thorax 61:854-62. 2006
    ....
  12. pmc Neighborhood poverty and the resurgence of tuberculosis in New York City, 1984-1992
    R G Barr
    Division of General Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Public Health 91:1487-93. 2001
    ..We assessed the relation between neighborhood poverty and TB at the height of the epidemic and longitudinally from 1984 through 1992...
  13. pmc Comorbidities, patient knowledge, and disease management in a national sample of patients with COPD
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Med 122:348-55. 2009
    ..We evaluated the prevalence of these comorbid conditions and compared testing, patient knowledge, and management in a national sample of patients with COPD...
  14. pmc Impaired flow-mediated dilation is associated with low pulmonary function and emphysema in ex-smokers: the Emphysema and Cancer Action Project (EMCAP) Study
    R Graham Barr
    Dr P H, Presbyterian Hospital 9 East, Room 105, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA
    Am J Respir Crit Care Med 176:1200-7. 2007
    ..Clinical studies examining endothelial function are lacking, particularly early in the disease. Flow-mediated dilation (FMD) is a physiologic measure of endothelial reactivity to endogenous nitric oxide...
  15. pmc Reproducibility and validity of a handheld spirometer
    R Graham Barr
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Respir Care 53:433-41. 2008
    ..Handheld spirometers have several advantages over desktop spirometers, but worries persist regarding reproducibility and validity of data from handheld spirometers. We undertook an independent examination of the EasyOne handheld spirometer...
  16. ncbi request reprint Tests of glycemia for the diagnosis of type 2 diabetes mellitus
    R Graham Barr
    Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ann Intern Med 137:263-72. 2002
    ..The glycemic threshold for type 2 diabetes should be established by cost-effectiveness analysis. The clinical diagnosis of diabetes mellitus could be streamlined by incorporation of hemoglobin A1c into established criteria...
  17. ncbi request reprint Hormone replacement therapy and obstructive airway diseases
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Treat Respir Med 3:1-7. 2004
    ....
  18. pmc The epidemiology of vascular dysfunction relating to chronic obstructive pulmonary disease and emphysema
    R Graham Barr
    Division of General Medicine, Department of Medicine, Columbia University Medical Center, New York, New York, USA
    Proc Am Thorac Soc 8:522-7. 2011
    ..These measures may also provide imaging-based surrogate markers, and novel therapeutics targeted to the pulmonary vasculature might reduce symptoms and improve function in these common diseases...
  19. ncbi request reprint Prospective study of acetaminophen use and newly diagnosed asthma among women
    R Graham Barr
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Am J Respir Crit Care Med 169:836-41. 2004
    ....
  20. pmc Methylxanthines for exacerbations of chronic obstructive pulmonary disease: meta-analysis of randomised trials
    R Graham Barr
    Division of General Medicine, PH 9 East Room 105, Columbia Presbyterian Medical Centre, 622 West 168th Street, New York, NY 10032, USA
    BMJ 327:643. 2003
    ..To evaluate the addition of methylxanthines to standard treatments in patients presenting with acute exacerbations of chronic obstructive pulmonary disease (COPD)...
  21. ncbi request reprint Chronic obstructive pulmonary disease, asthma, and risk of type 2 diabetes in women
    Jamal S Rana
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    Diabetes Care 27:2478-84. 2004
    ..Increasing evidence points toward a role of inflammation in the pathogenesis of type 2 diabetes. We wanted to determine the relation of COPD and asthma with the development of type 2 diabetes...
  22. pmc The association of pipe and cigar use with cotinine levels, lung function, and airflow obstruction: a cross-sectional study
    Josanna Rodriguez
    Columbia University Medical Center, PH 9 East, Room 105, 630 West 168th Street, New York, NY 10032, USA
    Ann Intern Med 152:201-10. 2010
    ..Cigarette smoking is the major cause of chronic obstructive pulmonary disease, but studies on the contribution of other smoking techniques are sparse...
  23. ncbi request reprint Prognosis in proliferative lupus nephritis: the role of socio-economic status and race/ethnicity
    R Graham Barr
    Columbia Presbyterian Medical Center, 622 West 168th Street, New York, NY 10032, USA
    Nephrol Dial Transplant 18:2039-46. 2003
    ..However, no study has simultaneously examined socio-economic status. We studied rates of progression of PLN among a tri-ethnic population with respect to socio-economic status and race/ethnicity...
  24. pmc Plasma carbonyls do not correlate with lung function or computed tomography measures of lung density in older smokers
    Sonia Mesia-Vela
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Biomarkers 13:422-34. 2008
    ..Plasma carbonyl content is a poor biomarker of oxidative stress in COPD and emphysema...
  25. pmc Cigarette smoking is associated with subclinical parenchymal lung disease: the Multi-Ethnic Study of Atherosclerosis (MESA)-lung study
    David J Lederer
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Am J Respir Crit Care Med 180:407-14. 2009
    ..Cigarette smoking is a risk factor for diffuse parenchymal lung disease. Risk factors for subclinical parenchymal lung disease have not been described...
  26. ncbi request reprint Ethnicity and sex modify the association of serum c-reactive protein with microalbuminuria
    Walter Palmas
    Department of Medicine, Mailman School of Public Health, Columbia University, New York, New York, USA
    Ethn Dis 18:324-9. 2008
    ..To study the association between serum C-reactive protein (CRP) and urinary albumin excretion in the Multi-Ethnic Study of Atherosclerosis and to assess whether the association is modified by ethnicity, sex, or systolic blood pressure...
  27. ncbi request reprint Patient factors and medication guideline adherence among older women with asthma
    R Graham Barr
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Arch Intern Med 162:1761-8. 2002
    ..Asthma guidelines are well established but often followed poorly. Determinants of adherence among older persons may differ from younger persons and have not been well characterized...
  28. pmc Validation of self-reported chronic obstructive pulmonary disease among patients in the ED
    Michael S Radeos
    Department of Emergency Medicine, New York Hospital Queens, Flushing, NY, USA
    Am J Emerg Med 27:191-6. 2009
    ..To determine whether the self-reported diagnosis of adults who present to the emergency department (ED) with an acute exacerbation of either asthma or chronic obstructive pulmonary disease (COPD) is validated by medical record review...
  29. pmc Association of environmental tobacco smoke exposure in childhood with early emphysema in adulthood among nonsmokers: the MESA-lung study
    Gina S Lovasi
    Mailman School of Public Health, 722 West 168th Street, Room 804, New York, NY 10032, USA
    Am J Epidemiol 171:54-62. 2010
    ..g., cumulative residential air pollution exposure, exposure to ETS as an adult). Childhood ETS exposure was associated with detectable differences on computed tomography scans of adult lungs of nonsmokers...
  30. pmc Associations of dairy intake with CT lung density and lung function
    Rui Jiang
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Am Coll Nutr 29:494-502. 2010
    ..However, the overall associations of dairy intake with lung density and lung function have not been studied...
  31. pmc Inflammatory markers and longitudinal lung function decline in the elderly
    Rui Jiang
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Epidemiol 168:602-10. 2008
    ..An alternative approach to missing data yielded similar results. In conclusion, higher levels of fibrinogen, but not CRP, independently predicted greater FEV(1)/FVC decline in the elderly...
  32. pmc Sex and racial/ethnic differences in cardiovascular disease risk factor treatment and control among individuals with diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Ginger J Winston
    Division of General Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Diabetes Care 32:1467-9. 2009
    ..CONCLUSIONS Women with diabetes had unfavorable cardiovascular risk factor profiles compared with men. African American and Hispanic women had less favorable profiles than non-Hispanic white women...
  33. pmc Endothelial dysfunction and the risk of hypertension: the multi-ethnic study of atherosclerosis
    Daichi Shimbo
    Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA
    Hypertension 55:1210-6. 2010
    ..In this sample, reduced FMD was not an independent predictor of hypertension incidence, suggesting that impaired endothelial function does not play a major role in the development of hypertension...
  34. pmc Prospective study of dietary patterns and chronic obstructive pulmonary disease among US women
    Raphaelle Varraso
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 86:488-95. 2007
    ..Although many foods and nutrients are associated with lung function or symptoms of chronic obstructive pulmonary disease (COPD), the relation between overall diet and newly diagnosed COPD is not known...
  35. pmc Racial differences in waiting list outcomes in chronic obstructive pulmonary disease
    David J Lederer
    Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, 622 West 168th Street, PH 8, Room 101, New York, NY 10032, USA
    Am J Respir Crit Care Med 177:450-4. 2008
    ..Blacks with chronic illness have poorer outcomes than whites in the United States. The health outcomes of minorities with chronic obstructive pulmonary disease (COPD) on the lung transplant waiting list have not been studied...
  36. pmc Cured meat consumption, lung function, and chronic obstructive pulmonary disease among United States adults
    Rui Jiang
    Division of General Medicine, Department of Medicine, Columbia University, New York, New York 10032, USA
    Am J Respir Crit Care Med 175:798-804. 2007
    ..Cured meats are high in nitrites. Nitrites generate reactive nitrogen species that may cause nitrative and nitrosative damage to the lung resulting in emphysema...
  37. ncbi request reprint Antihypertensive medications and C-reactive protein in the multi-ethnic study of atherosclerosis
    Walter Palmas
    Division of General Medicine, Department of Medicine, Mailman School of Public Health, Columbia University Medical Center, New York, New York
    Am J Hypertens 20:233-41. 2007
    ..The effects of different antihypertensive medication classes on C-reactive protein (CRP) levels are still not well characterized, and might be of relevance to treatment choices...
  38. ncbi request reprint Prospective study of short stature and newly diagnosed asthma in women
    Deborah P Jones
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Asthma 44:291-5. 2007
    ..26-1.91). After adjustment for body mass index, the rate ratio was 1.16 (95% CI, 0.94-1.42). Short stature predicted adult-onset asthma in a large cohort of women, but this association was not independent of obesity...
  39. ncbi request reprint Risk factors for venous thromboembolism after lung transplantation
    Hilary A Yegen
    Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Chest 132:547-53. 2007
    ..The risk factors for venous thromboembolism (VTE) following lung transplantation are not well established. We aimed to estimate the incidence of VTE and to identify the risk factors for VTE after lung transplantation...
  40. pmc Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort
    Matthew S Perzanowski
    Columbia Center for Children s Environmental Health CCCEH, New York, NY 10032, USA
    Thorax 65:118-23. 2010
    ....
  41. pmc Randomised aspirin assignment and risk of adult-onset asthma in the Women's Health Study
    T Kurth
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave East, 3rd Floor, Boston, MA 02215, USA
    Thorax 63:514-8. 2008
    ..A study was undertaken to test the effect of 100 mg aspirin or placebo on alternate days on the risk of adult-onset asthma in the Women's Health Study...
  42. pmc Does the relationship between asthma and obesity differ by neighborhood?
    Emily S Tonorezos
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, New York University, New York, NY, USA
    Respir Med 102:1797-804. 2008
    ..Prior studies suggest that obesity may cause asthma. Obesity and asthma are prevalent in low-income urban neighborhoods, but the impact of obesity on asthma in such neighborhoods has not been examined...
  43. ncbi request reprint Nut and seed consumption and inflammatory markers in the multi-ethnic study of atherosclerosis
    Rui Jiang
    Division of General Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Am J Epidemiol 163:222-31. 2006
    ..Frequent nut and seed consumption was associated with lower levels of inflammatory markers, which may partially explain the inverse association of nut consumption with cardiovascular disease and diabetes risk...
  44. ncbi request reprint Prospective study of postmenopausal hormone use and newly diagnosed asthma and chronic obstructive pulmonary disease
    R Graham Barr
    Department of Medicine, Brigham and Women s Hospital, Massachusetts General Hospital, Harvard Medical School, Boston, Massachesetts, USA
    Arch Intern Med 164:379-86. 2004
    ..Therefore, in a prospective cohort study, we evaluated whether postmenopausal hormone use was associated with an increased rate of newly diagnosed asthma and, separately, newly diagnosed COPD...
  45. ncbi request reprint Validation of self-reported chronic obstructive pulmonary disease in a cohort study of nurses
    R Graham Barr
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Epidemiol 155:965-71. 2002
    ..In conclusion, COPD can be studied in large, questionnaire-based cohorts of health professionals...
  46. pmc Consumption of cured meats and prospective risk of chronic obstructive pulmonary disease in women
    Rui Jiang
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 87:1002-8. 2008
    ..Nitrites generate oxidative-nitrative stress and were shown in animal models to cause emphysema. Prospective epidemiologic data on cured meats and chronic obstructive pulmonary disease (COPD), however, are sparse...
  47. pmc Left ventricular mass and ventricular remodeling among Hispanic subgroups compared with non-Hispanic blacks and whites: MESA (Multi-ethnic Study of Atherosclerosis)
    Carlos J Rodriguez
    Department of Medicine, Mailman School of Public Health, Columbia University, New York, New York, USA
    J Am Coll Cardiol 55:234-42. 2010
    ....
  48. ncbi request reprint Racial and ethnic disparities in idiopathic pulmonary fibrosis: A UNOS/OPTN database analysis
    D J Lederer
    Department of Medicine, College of Physicians and Surgeons, Joseph L Mailman School of Public Health, Columbia University, New York, NY, USA
    Am J Transplant 6:2436-42. 2006
    ..16, 95% CI 0.98-1.36, p = 0.09; HR for Hispanics = 1.21, 95% CI 0.99-1.48, p = 0.056). In summary, black and Hispanic patients with IPF have worse survival than whites after listing for lung transplant...
  49. ncbi request reprint Beta(2)-adrenoceptor polymorphism and body mass index are associated with adult-onset asthma in sedentary but not active women
    R G Barr
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Chest 120:1474-9. 2001
    ..In addition, BMI predicts asthma. We hypothesized that these DNA sequence variants predict adult-onset asthma only in sedentary women...
  50. ncbi request reprint Race/ethnicity, poverty status, and renal transplant outcomes
    Rebecca Press
    Division of General Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Transplantation 80:917-24. 2005
    ..Our goal was to test if African-American and Hispanic race/ethnicity and poverty are associated with worse outcomes following renal transplantation...
  51. pmc Pesticide spraying for West Nile virus control and emergency department asthma visits in New York City, 2000
    Adam M Karpati
    Division of Disease Control, New York City Department of Health and Mental Hygiene, New York, NY, USA
    Environ Health Perspect 112:1183-7. 2004
    ..This analysis shows that spraying pyrethroids for WNV control in New York City was not followed by population-level increases in public hospital ED visit rates for asthma...
  52. pmc Endotoxin in inner-city homes: associations with wheeze and eczema in early childhood
    Matthew S Perzanowski
    Columbia s Center for Children s Environmental Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 117:1082-9. 2006
    ..The relevance of this aspect of the hygiene hypothesis to US inner-city communities that have disproportionately high asthma prevalence has not been determined...
  53. pmc Aspirin and decreased adult-onset asthma: randomized comparisons from the physicians' health study
    R Graham Barr
    Division of General Medicine, Department of Medicine, Columbia University Medical Center, New York, NY, USA
    Am J Respir Crit Care Med 175:120-5. 2007
    ..In an observational cohort study, women who self-selected for frequent aspirin use developed less newly diagnosed asthma than women who did not take aspirin...
  54. pmc Prospective study of cured meats consumption and risk of chronic obstructive pulmonary disease in men
    Raphaelle Varraso
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Epidemiol 166:1438-45. 2007
    ..00; p(trend) = 0.002). In contrast to these findings, the consumption of cured meats was not associated with the risk of adult-onset asthma. These data suggest that cured meat may worsen the adverse effects of smoking on risk of COPD...
  55. pmc Prospective study of inhaled corticosteroid use, cardiovascular mortality, and all-cause mortality in asthmatic women
    Carlos A Camargo
    Massachusetts General Hospital, 326 Cambridge Street, Boston, MA 02114, USA
    Chest 134:546-51. 2008
    ..Recent studies have suggested that ICS therapy also may decrease the risk of cardiovascular disease, and perhaps of all-cause mortality. We examined this hypothesis in a large, well-characterized cohort of asthmatic women...
  56. ncbi request reprint Acute exacerbations of chronic obstructive pulmonary disease
    R Graham Barr
    N Engl J Med 347:1533-4; author reply 1533-4. 2002
  57. ncbi request reprint Acetaminophen and the risk of asthma: the epidemiologic and pathophysiologic evidence
    Ihuoma Eneli
    Department of Pediatrics and Human Development, Michigan State University, B220 Clinical Center Bldg, East Lansing, MI 48824 1313, USA
    Chest 127:604-12. 2005
    ..This article reviews the existing literature and evaluates the epidemiologic and pathophysiologic evidence underlying a possible link between acetaminophen and asthma...
  58. ncbi request reprint Management of chronic obstructive pulmonary disease
    R Graham Barr
    JAMA 291:1066-7; author reply 1067. 2004
  59. ncbi request reprint Prospective study of sudden-onset asthma exacerbations in children
    Hanan A Sedik
    Division of Emergency Medicine, Childrens Hospital Los Angeles, Los Angeles, CA 90027, USA
    Pediatr Emerg Care 23:439-44. 2007
    ..We hypothesized that a similar pattern would be evident in children presenting to the emergency department (ED) with an asthma exacerbation...
  60. ncbi request reprint Domestic returns from investment in the control of tuberculosis in other countries
    Kevin Schwartzman
    Respiratory Epidemiology Unit, Montreal Chest Institute, McGill University, Montreal, QC, Canada
    N Engl J Med 353:1008-20. 2005
    ..We hypothesized that investments to improve the control of tuberculosis in selected high-incidence countries would prove to be cost saving for the United States by reducing the incidence of the disease among migrants...
  61. ncbi request reprint Intakes of long-chain n-3 polyunsaturated fatty acids and fish in relation to measurements of subclinical atherosclerosis
    Ka He
    Department of Nutrition, School of Public Health and School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Am J Clin Nutr 88:1111-8. 2008
    ..Data on the relations of different types of fish meals and long-chain n-3 polyunsaturated fatty acids (PUFAs) to measures of atherosclerosis are sparse...
  62. doi request reprint Long-term exposure to ambient particulate matter and prevalence of subclinical atherosclerosis in the Multi-Ethnic Study of Atherosclerosis
    Ana V Diez Roux
    Department of Epidemiology, University of Michigan, Ann Arbor, MI 48104, USA
    Am J Epidemiol 167:667-75. 2008
    ..Results are compatible with some effect of particulate matter exposures on development of carotid atherosclerosis...

Research Grants13

  1. Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)
    R Barr; Fiscal Year: 2009
    ..If confirmed, this hypothesis would lead to the testing of currently available (e.g., statins) and novel (e.g., stem cell) therapies targeted to the endothelium in COPD. ..
  2. Endothelial Dysfunction, Biomarkers and Lung Function
    R Barr; Fiscal Year: 2005
    ..This novel hypothesis, if confirmed, has the potential to lead directly to the testing of currently available therapies for endothelial dysfunction in COPD. ..
  3. Endothelial Dysfunction, Biomarkers and Lung Function
    R Barr; Fiscal Year: 2006
    ..This novel hypothesis, if confirmed, has the potential to lead directly to the testing of currently available therapies for endothelial dysfunction in COPD. ..
  4. Fish Oil Intake, Biomarkers and Change in Lung Function
    R Barr; Fiscal Year: 2004
    ..Use of this existing cohort with previously collected blood samples will provide relatively cost-effective results about this potentially promising and safe therapy for COPD. ..
  5. Cardiopulmonary structure and function in Multi-Ethnic Study of Atherosclerosis
    R Graham Barr; Fiscal Year: 2010
    ..This study will examine if a particular kind of heart failure (with preserved ejection fraction or "diastolic" heart failure) is caused in part by and may share pathogenesis with subclinical lung disease. ..
  6. Endothelial Dysfunction, Biomarkers and Lung Function
    R Barr; Fiscal Year: 2007
    ..This novel hypothesis, if confirmed, has the potential to lead directly to the testing of currently available therapies for endothelial dysfunction in COPD. ..
  7. Fish Oil Intake, Biomarkers and Change in Lung Function
    R Barr; Fiscal Year: 2007
    ..Use of this existing cohort with previously collected blood samples will provide relatively cost-effective results about this potentially promising and safe therapy for COPD. ..
  8. Fish Oil Intake, Biomarkers and Change in Lung Function
    R Barr; Fiscal Year: 2006
    ..Use of this existing cohort with previously collected blood samples will provide relatively cost-effective results about this potentially promising and safe therapy for COPD. ..
  9. Fish Oil Intake, Biomarkers and Change in Lung Function
    R Barr; Fiscal Year: 2005
    ..Use of this existing cohort with previously collected blood samples will provide relatively cost-effective results about this potentially promising and safe therapy for COPD. ..
  10. Endothelial Dysfunction, Biomarkers and Lung Function
    R Barr; Fiscal Year: 2004
    ..This novel hypothesis, if confirmed, has the potential to lead directly to the testing of currently available therapies for endothelial dysfunction in COPD. ..
  11. Pulmonary Vascular Changes in Early Chronic Obstructive Pulmonary Disease (COPD)
    R Graham Barr; Fiscal Year: 2010
    ..If confirmed, this hypothesis would lead to the testing of currently available (e.g., statins) and novel (e.g., stem cell) therapies targeted to the endothelium in COPD. ..