Miron Baron

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Genetic linkage and bipolar affective disorder: progress and pitfalls
    M Baron
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Mol Psychiatry 2:200-10. 1997
  2. ncbi request reprint Manic-depression genes and the new millennium: poised for discovery
    M Baron
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and Department of Medical Genetics, New York State Psychiatric Institute, New York 10032, USA
    Mol Psychiatry 7:342-58. 2002
  3. ncbi request reprint The search for complex disease genes: fault by linkage or fault by association?
    M Baron
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Mol Psychiatry 6:143-9. 2001
  4. pmc Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network
    Ivan Iossifov
    Department of Biomedical Informatics, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York 10032, USA
    Genome Res 18:1150-62. 2008
  5. pmc Fine mapping of candidate regions for bipolar disorder provides strong evidence for susceptibility loci on chromosomes 7q
    Haiyan Xu
    Department of Genetics and Development, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Am J Med Genet B Neuropsychiatr Genet 156:168-76. 2011
  6. ncbi request reprint Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder
    R Cheng
    Columbia Genome Center, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 11:252-60. 2006
  7. ncbi request reprint A follow-up linkage study supports evidence for a bipolar affective disorder locus on chromosome 21q22
    J Liu
    Columbia Genome Center, Columbia University, New York, New York, USA
    Am J Med Genet 105:189-94. 2001
  8. ncbi request reprint Linkage analysis of psychosis in bipolar pedigrees suggests novel putative loci for bipolar disorder and shared susceptibility with schizophrenia
    N Park
    Columbia Genome Center, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 9:1091-9. 2004
  9. ncbi request reprint Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12
    J Liu
    Columbia Genome Center and Department o fPsychiatry, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 8:333-42. 2003
  10. ncbi request reprint Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation
    J Gecz
    Department of Cytogenetics and Molecular Genetics, Women s and Children s Hospital, North Adelaide, South Australia, 5006, Australia
    Genomics 62:356-68. 1999

Research Grants

  1. MOLECULAR GENETICS OF BIPOLAR DISORDER
    Miron Baron; Fiscal Year: 2001

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Genetic linkage and bipolar affective disorder: progress and pitfalls
    M Baron
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Mol Psychiatry 2:200-10. 1997
    ..Indeed, recent reports of putative loci on chromosomes 18, 21, X, 4, 6, 13 and 15 have rekindled a sense of optimism. The new findings are reviewed and scrutinized, with implications for future research...
  2. ncbi request reprint Manic-depression genes and the new millennium: poised for discovery
    M Baron
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and Department of Medical Genetics, New York State Psychiatric Institute, New York 10032, USA
    Mol Psychiatry 7:342-58. 2002
    ..The progress to date, together with rapid advances in genomics, analytical and computational methods, and bioinformatics, holds promise for new insights into the genetics of manic-depression, in the new millennium...
  3. ncbi request reprint The search for complex disease genes: fault by linkage or fault by association?
    M Baron
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Mol Psychiatry 6:143-9. 2001
    ....
  4. pmc Genetic-linkage mapping of complex hereditary disorders to a whole-genome molecular-interaction network
    Ivan Iossifov
    Department of Biomedical Informatics, Center for Computational Biology and Bioinformatics, Columbia University, New York, New York 10032, USA
    Genome Res 18:1150-62. 2008
    ....
  5. pmc Fine mapping of candidate regions for bipolar disorder provides strong evidence for susceptibility loci on chromosomes 7q
    Haiyan Xu
    Department of Genetics and Development, Columbia University, 630 West 168th Street, New York, NY 10032, USA
    Am J Med Genet B Neuropsychiatr Genet 156:168-76. 2011
    ..Somewhat lesser, yet notable support was obtained for 2p13, 4q31, 8q13, 13q32, 14q21, and 17q11. These regions could be considered prime candidates for future gene finding efforts...
  6. ncbi request reprint Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder
    R Cheng
    Columbia Genome Center, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 11:252-60. 2006
    ..This is the first large-scale linkage scan of bipolar disorder to analyze simultaneously bipolar disorder, psychosis, suicidal behavior, and panic disorder...
  7. ncbi request reprint A follow-up linkage study supports evidence for a bipolar affective disorder locus on chromosome 21q22
    J Liu
    Columbia Genome Center, Columbia University, New York, New York, USA
    Am J Med Genet 105:189-94. 2001
    ..56 with D21S1260. The 16 new pedigrees analyzed separately gave a maximum two-point lod score of 1.89 at D21S266, less than 1 cM proximal to D21S1260. Our results are consistent with a putative BP locus on 21q22...
  8. ncbi request reprint Linkage analysis of psychosis in bipolar pedigrees suggests novel putative loci for bipolar disorder and shared susceptibility with schizophrenia
    N Park
    Columbia Genome Center, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 9:1091-9. 2004
    ..Our results suggest that BP in conjunction with psychosis is a potentially useful phenotype that may: (1) expedite the detection of susceptibility loci for BP and (2) cast light on the genetic relationship between BP and schizophrenia...
  9. ncbi request reprint Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12
    J Liu
    Columbia Genome Center and Department o fPsychiatry, Columbia University, New York, NY 10032, USA
    Mol Psychiatry 8:333-42. 2003
    ..Two of the regions implicated in our study, 2p13-14 and 13q32, have also been linked to schizophrenia, suggesting that the two disorders may have susceptibility genes in common...
  10. ncbi request reprint Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation
    J Gecz
    Department of Cytogenetics and Molecular Genetics, Women s and Children s Hospital, North Adelaide, South Australia, 5006, Australia
    Genomics 62:356-68. 1999
    ..No evidence of linkage was found by parametric Lod score analysis (the highest Lod score was 0. 3 at DXS1212, using the dominant transmission model) or by affected sib-pair analysis...
  11. ncbi request reprint Absence of psychosis may influence linkage results for bipolar disorder
    N Park
    Mol Psychiatry 10:235-7. 2005
  12. ncbi request reprint Psychosis and the genetic spectrum of bipolar disorder: evidence from linkage analysis
    R Cheng
    Mol Psychiatry 11:3-5. 2006
  13. pmc Genetic characterization of the Drosophila melanogaster Suppressor of deltex gene: A regulator of notch signaling
    M Fostier
    University of Manchester, School of Biological Sciences, Manchester M13 9PT, United Kingdom
    Genetics 150:1477-85. 1998
    ..This corresponds to the period when the Notch protein is involved in refining the vein competent territories. Taken together, our data indicate a role for Su(dx) as a negative regulator of Notch function...

Research Grants4

  1. MOLECULAR GENETICS OF BIPOLAR DISORDER
    Miron Baron; Fiscal Year: 2001
    ..This, in turn, may have important implications for the etiology, nosology, pathophysiology and, possibly, prevention and treatment of this disorder. ..