Jonathan M Barasch

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study
    Catherine L Dent
    Department of Cardiology, Cincinnati Children s Hospital Medical Center, University of Cincinnati School of Medicine, 3333 Burnet Ave, Cincinnati, Ohio 45229, USA
    Crit Care 11:R127. 2007
  2. pmc Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros
    J Barasch
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Invest 103:1299-307. 1999
  3. ncbi request reprint Mesenchymal to epithelial conversion in rat metanephros is induced by LIF
    J Barasch
    Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Cell 99:377-86. 1999
  4. ncbi request reprint Genes and proteins involved in mesenchymal to epithelial transition
    J Barasch
    Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Curr Opin Nephrol Hypertens 10:429-36. 2001
  5. pmc Urinary neutrophil gelatinase-associated lipocalin is a promising biomarker for late onset culture-positive sepsis in very low birth weight infants
    Elvira Parravicini
    Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Pediatr Res 67:636-40. 2010
  6. ncbi request reprint Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro
    J van Adelsberg
    Columbia University College of Physicians and Surgeons, Department of Medicine, New York, New York 10032, USA
    J Biol Chem 276:15099-106. 2001
  7. pmc Reference values of urinary neutrophil gelatinase-associated lipocalin in very low birth weight infants
    Trang K Huynh
    Division of Newborn Medicine, Department of Pediatrics, New York Presbyterian Hospital Weill Cornell Medical College, New York, New York 10065, USA
    Pediatr Res 66:528-32. 2009
  8. ncbi request reprint Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery
    Gebhard Wagener
    Department of Anesthesiology, Columbia University, NY 10032 3784, USA
    Anesthesiology 105:485-91. 2006

Research Grants

  1. CYTOKINES CONVERT EPITHELIAL PRECURSORS TO NEPHRONS
    Jonathan M Barasch; Fiscal Year: 2010
  2. CYTOKINES CONVERT EPITHELIAL PRECURSORS TO NEPHRONS
    Jonathan Barasch; Fiscal Year: 2007
  3. Iron Lipocalin in Kidney Disease
    Jonathan Barasch; Fiscal Year: 2007
  4. CYTOKINES CONVERT EPITHELIAL PRECURSORS TO NEPHRONS
    Jonathan Barasch; Fiscal Year: 2005
  5. Iron Lipcalin In Kidney Disease
    Jonathan M Barasch; Fiscal Year: 2011

Collaborators

Detail Information

Publications8

  1. pmc Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study
    Catherine L Dent
    Department of Cardiology, Cincinnati Children s Hospital Medical Center, University of Cincinnati School of Medicine, 3333 Burnet Ave, Cincinnati, Ohio 45229, USA
    Crit Care 11:R127. 2007
    ..In this study we tested whether a point-of-care NGAL device can predict AKI after CPB in a larger cohort...
  2. pmc Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros
    J Barasch
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Clin Invest 103:1299-307. 1999
    ..Hence, the mesenchyme synchronizes its own growth with ureteric morphogenesis by stimulating the secretion of TIMP-2 from the ureteric bud...
  3. ncbi request reprint Mesenchymal to epithelial conversion in rat metanephros is induced by LIF
    J Barasch
    Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Cell 99:377-86. 1999
    ..In situ, the ureteric bud expressed LIF, and metanephric mesenchyme expressed its receptors. The data suggest that IL-6 cytokines are candidate regulators of mesenchymal to epithelial conversion during kidney development...
  4. ncbi request reprint Genes and proteins involved in mesenchymal to epithelial transition
    J Barasch
    Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Curr Opin Nephrol Hypertens 10:429-36. 2001
    ..The metanephric kidney, Wolffian duct, and the Drosophila midgut are the leading model systems to describe how epithelia derive from mesenchyme...
  5. pmc Urinary neutrophil gelatinase-associated lipocalin is a promising biomarker for late onset culture-positive sepsis in very low birth weight infants
    Elvira Parravicini
    Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Pediatr Res 67:636-40. 2010
    ..05 to <0.005). uNGAL shows promise as an early marker for culture-positive sepsis in VLBW infants...
  6. ncbi request reprint Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro
    J van Adelsberg
    Columbia University College of Physicians and Surgeons, Department of Medicine, New York, New York 10032, USA
    J Biol Chem 276:15099-106. 2001
    ..The creation and shape of gradients of activated HGF by the localized secretion of HGF activators could play an important role in pattern formation by HGF responsive tissues...
  7. pmc Reference values of urinary neutrophil gelatinase-associated lipocalin in very low birth weight infants
    Trang K Huynh
    Division of Newborn Medicine, Department of Pediatrics, New York Presbyterian Hospital Weill Cornell Medical College, New York, New York 10065, USA
    Pediatr Res 66:528-32. 2009
    ..Greater variability and higher quantile levels of UNGAL were observed in females versus males. In conclusion, a reference range for UNGAL in VLBW infants, similar to that in children and adults, has been established...
  8. ncbi request reprint Association between increases in urinary neutrophil gelatinase-associated lipocalin and acute renal dysfunction after adult cardiac surgery
    Gebhard Wagener
    Department of Anesthesiology, Columbia University, NY 10032 3784, USA
    Anesthesiology 105:485-91. 2006
    ..The authors hypothesized that postoperative urinary NGAL concentrations are increased in adult patients developing ARD after cardiac surgery compared with patients without ARD...

Research Grants16

  1. CYTOKINES CONVERT EPITHELIAL PRECURSORS TO NEPHRONS
    Jonathan M Barasch; Fiscal Year: 2010
    ..We apply the basic ideas and tools of cell biologyto define the course of polarization and establish a fluorescent polarity mouse to evaluate the entire transition form mesenchyme to epithelia. ..
  2. CYTOKINES CONVERT EPITHELIAL PRECURSORS TO NEPHRONS
    Jonathan Barasch; Fiscal Year: 2007
    ....
  3. Iron Lipocalin in Kidney Disease
    Jonathan Barasch; Fiscal Year: 2007
    ..This work is important because it characterizes a novel growth factor that is massively expressed by damaged renal epithelia and it evaluates a novel iron transport pathway that appears critical to Ngal function. ..
  4. CYTOKINES CONVERT EPITHELIAL PRECURSORS TO NEPHRONS
    Jonathan Barasch; Fiscal Year: 2005
    ....
  5. Iron Lipcalin In Kidney Disease
    Jonathan M Barasch; Fiscal Year: 2011
    ..This work is important because it characterizes a novel growth factorthat is massively expressed by damaged renal epithelia and it evaluates a novel iron transport pathwaythat appears critical to Ngal function. ..