J M Angelastro

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins
    James M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, 630 W, 168th Street, New York, NY 10032, USA
    BMC Neurosci 3:3. 2002
  2. pmc Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols
    J M Angelastro
    Department of Pathology and Taub Center for Alzheimer s Disease Research and Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Nucleic Acids Res 28:E62. 2000
  3. ncbi request reprint Characterization of a novel isoform of caspase-9 that inhibits apoptosis
    J M Angelastro
    Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Biol Chem 276:12190-200. 2001
  4. ncbi request reprint Blue-white selection step enhances the yield of SAGE concatemers
    J M Angelastro
    Department of Pathology, Columbia University, College of Physicians and Surgeons, Center for Neurobiology and Behavior, New York, NY 10032, USA
    Biotechniques 32:484, 486. 2002
  5. ncbi request reprint Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons
    James M Angelastro
    Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 23:4590-600. 2003
  6. ncbi request reprint Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation
    C M Troy
    Department of Pathology, Taub Institute for the Study of Alzheimer s Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 21:5007-16. 2001
  7. ncbi request reprint RAIDD aggregation facilitates apoptotic death of PC12 cells and sympathetic neurons
    O Jabado
    Department of Neurology, Columbia University, USA
    Cell Death Differ 11:618-30. 2004
  8. ncbi request reprint Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine
    J M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Neurochem 70:540-9. 1998
  9. ncbi request reprint Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5
    J M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Oncogene 25:907-16. 2006
  10. ncbi request reprint Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors
    C Volonte
    Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, New York 10032
    J Biol Chem 268:21410-5. 1993

Collaborators

Detail Information

Publications17

  1. pmc Nerve growth factor selectively regulates expression of transcripts encoding ribosomal proteins
    James M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, 630 W, 168th Street, New York, NY 10032, USA
    BMC Neurosci 3:3. 2002
    ..Here, we used database information to identify transcripts in our SAGE libraries that encode ribosomal proteins and have compared the effect of NGF on their relative levels of expression...
  2. pmc Improved NlaIII digestion of PAGE-purified 102 bp ditags by addition of a single purification step in both the SAGE and microSAGE protocols
    J M Angelastro
    Department of Pathology and Taub Center for Alzheimer s Disease Research and Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Nucleic Acids Res 28:E62. 2000
    ..This allows us to increase the yield of digested ditags without reducing the amount of DNA or affecting the subsequent concatemerization...
  3. ncbi request reprint Characterization of a novel isoform of caspase-9 that inhibits apoptosis
    J M Angelastro
    Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Biol Chem 276:12190-200. 2001
    ..Taken together, our observations indicate that casp-9-CTD acts as a dominant-negative variant. Its expression in various tissues indicates a physiological role in regulating cell death...
  4. ncbi request reprint Blue-white selection step enhances the yield of SAGE concatemers
    J M Angelastro
    Department of Pathology, Columbia University, College of Physicians and Surgeons, Center for Neurobiology and Behavior, New York, NY 10032, USA
    Biotechniques 32:484, 486. 2002
  5. ncbi request reprint Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons
    James M Angelastro
    Department of Pathology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 23:4590-600. 2003
    ..These findings indicate that ATF5 blocks the differentiation of neuroprogenitor cells into neurons and must be downregulated to permit this process to occur...
  6. ncbi request reprint Death in the balance: alternative participation of the caspase-2 and -9 pathways in neuronal death induced by nerve growth factor deprivation
    C M Troy
    Department of Pathology, Taub Institute for the Study of Alzheimer s Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 21:5007-16. 2001
    ..The choice of the death-mediating caspase pathway in the sympathetic neurons is thus dependent on the regulated relative expression of components of the pathways including those of caspases, IAPs, and IAP inhibitors...
  7. ncbi request reprint RAIDD aggregation facilitates apoptotic death of PC12 cells and sympathetic neurons
    O Jabado
    Department of Neurology, Columbia University, USA
    Cell Death Differ 11:618-30. 2004
    ..Therefore, RAIDD aggregation is important for its death-promoting effects and may play a role in trophic factor withdrawal-induced neuronal apoptosis...
  8. ncbi request reprint Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine
    J M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Neurochem 70:540-9. 1998
    ..2 vim- cells. This indicates that tyrosine phosphorylation of the peripherin C-terminal residue is not required for assembly and leaves open the possibility that this modification serves other functions...
  9. ncbi request reprint Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5
    J M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Oncogene 25:907-16. 2006
    ..The widespread expression of ATF5 in glioblastomas and the selective effect of interference with ATF5 function/expression on their survival suggest that ATF5 may be an attractive target for therapeutic intervention in such tumors...
  10. ncbi request reprint Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors
    C Volonte
    Department of Pathology, College of Physicians and Surgeons of Columbia University, New York, New York 10032
    J Biol Chem 268:21410-5. 1993
    ..These findings indicate that NGF, via activation of gp140prototrk, leads to association of enzymatically active ERKs with p75 and raise the possibility that this interaction may play a role in the NGF mechanism of action...
  11. ncbi request reprint You can't go home again: transcriptionally driven alteration of cell signaling by NGF
    Lloyd A Greene
    Department of Pathology, Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurochem Res 30:1347-52. 2005
    ..We discuss specific examples based on reports in the literature as well as on data derived from a serial analysis of gene expression (SAGE) study of NGF-promoted transcriptional changes in PC12 pheochromocytoma cells...
  12. ncbi request reprint ATF5 regulates the proliferation and differentiation of oligodendrocytes
    Jeffrey L Mason
    Farber Institute for Neurosciences, Thomas Jefferson University, Philadelphia, PA 19107, USA
    Mol Cell Neurosci 29:372-80. 2005
    ..Regulation of oligodendrocyte, astrocyte, and neuronal differentiation indicates that ATF5 operates as a general regulator of the timing of differentiation, independent of cell lineage...
  13. ncbi request reprint Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes
    James M Angelastro
    Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 25:3889-99. 2005
    ..These findings identify ATF5 as a key regulator of astrocyte formation and potentially of the VZ to SVZ transition...
  14. ncbi request reprint Analysis of gene expression changes in a cellular model of Parkinson disease
    Elizabeth J Ryu
    Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Neurobiol Dis 18:54-74. 2005
    ..Such intervention may include both inhibiting the induction/activity of death-promoting genes and enhancing those with neuroprotective activity...
  15. ncbi request reprint Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
    Elizabeth J Ryu
    Department of Pathology, Center for Neurobiology and Behavior, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 22:10690-8. 2002
    ..Our findings, coupled with evidence from familial forms of Parkinson's disease, raise the possibility of widespread involvement of endoplasmic reticulum stress and the unfolded protein response in the pathophysiology of this disease...
  16. ncbi request reprint The basic region and leucine zipper transcription factor MafK is a new nerve growth factor-responsive immediate early gene that regulates neurite outgrowth
    Beata Torocsik
    Department of Pathology and Center for Neurobiology and Behavior, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Neurosci 22:8971-80. 2002
    ..Our findings support a role for MafK as a novel regulator of neuronal differentiation...
  17. ncbi request reprint Organotypic distribution of stem cell markers in formalin-fixed brain harboring glioblastoma multiforme
    Rudolph J Schrot
    Department of Neurological Surgery, UC Davis Medical Center, 4860 Y Street, Suite 3740, Sacramento, CA 95817, USA
    J Neurooncol 85:149-57. 2007
    ....