D B Allison

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Assortative mating for relative weight: genetic implications
    D B Allison
    Obesity Research Center, Saint Luke s Roosevelt Hospital, Columbia University College of, Physicians and Surgeons, New York, New York 10025, USA
    Behav Genet 26:103-11. 1996
  2. pmc Sibling-based tests of linkage and association for quantitative traits
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Hum Genet 64:1754-63. 1999
  3. ncbi request reprint Weight loss increases and fat loss decreases all-cause mortality rate: results from two independent cohort studies
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Int J Obes Relat Metab Disord 23:603-11. 1999
  4. pmc Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Hum Genet 65:531-44. 1999
  5. pmc The direct health care costs of obesity in the United States
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Public Health 89:1194-9. 1999
  6. ncbi request reprint Meta-analysis of the effect of excluding early deaths on the estimated relationship between body mass index and mortality
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Obes Res 7:342-54. 1999
  7. ncbi request reprint Annual deaths attributable to obesity in the United States
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    JAMA 282:1530-8. 1999
  8. ncbi request reprint Antipsychotic-induced weight gain: a comprehensive research synthesis
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, NY 10025, UDA
    Am J Psychiatry 156:1686-96. 1999
  9. ncbi request reprint Obesity in North America. An overview
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Med Clin North Am 84:305-32, v. 2000
  10. pmc Testing the robustness of the new Haseman-Elston quantitative-trait loci-mapping procedure
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Hum Genet 67:249-52. 2000

Detail Information

Publications38

  1. ncbi request reprint Assortative mating for relative weight: genetic implications
    D B Allison
    Obesity Research Center, Saint Luke s Roosevelt Hospital, Columbia University College of, Physicians and Surgeons, New York, New York 10025, USA
    Behav Genet 26:103-11. 1996
    ..The implications of these findings for heritability studies, linkage studies, and the estimation of shared environmental effects are discussed...
  2. pmc Sibling-based tests of linkage and association for quantitative traits
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Hum Genet 64:1754-63. 1999
    ..The second procedure is a permutation-based procedure. Selected power studies are conducted to illustrate the relative power of each test under a variety of circumstances...
  3. ncbi request reprint Weight loss increases and fat loss decreases all-cause mortality rate: results from two independent cohort studies
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Int J Obes Relat Metab Disord 23:603-11. 1999
    ..No study has considered the independent effects of weight loss and fat loss on mortality rate. We studied mortality rate as a function of weight loss and fat loss...
  4. pmc Testing the robustness of the likelihood-ratio test in a variance-component quantitative-trait loci-mapping procedure
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Am J Hum Genet 65:531-44. 1999
    ....
  5. pmc The direct health care costs of obesity in the United States
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Public Health 89:1194-9. 1999
    ..This article examines whether the estimated direct health care costs attributable to obesity are offset by the increased mortality rate among obese individuals...
  6. ncbi request reprint Meta-analysis of the effect of excluding early deaths on the estimated relationship between body mass index and mortality
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Obes Res 7:342-54. 1999
    ..This meta-analysis tests the effects of such early death exclusion on the BMI-mortality association...
  7. ncbi request reprint Annual deaths attributable to obesity in the United States
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    JAMA 282:1530-8. 1999
    ..Obesity is a major health problem in the United States, but the number of obesity-attributable deaths has not been rigorously estimated...
  8. ncbi request reprint Antipsychotic-induced weight gain: a comprehensive research synthesis
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, NY 10025, UDA
    Am J Psychiatry 156:1686-96. 1999
    ..The purpose of this study was to estimate and compare the effects of antipsychotics-both the newer ones and the conventional ones-on body weight...
  9. ncbi request reprint Obesity in North America. An overview
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Med Clin North Am 84:305-32, v. 2000
    ..This article discusses such issues as prevalence, morbidity, mortality, and psychosocial effects. Definitions and various classifications of obesity are discussed also...
  10. pmc Testing the robustness of the new Haseman-Elston quantitative-trait loci-mapping procedure
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Hum Genet 67:249-52. 2000
    ..for the ML approach (i.e., 100 pairs; high residual sibling correlation). Results showed that, when marked nonnormality is present, the NHE can be used without severe type I error-rate inflation, even at very small alpha levels...
  11. ncbi request reprint Alternative treatments for weight loss: a critical review
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Crit Rev Food Sci Nutr 41:1-28; discussion 39-40. 2001
    ..Nevertheless, some have plausible mechanisms of action and encouraging preliminary data that are sufficiently provocative to merit further research...
  12. ncbi request reprint Metabolic disharmony and mortality
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, NY 10025, USA
    Med Hypotheses 56:604-9. 2001
    ..g., smoking status) were added to the model or when all subjects were included by imputing missing data. These results demonstrate that metabolic disharmony is associated with, and may cause, an increased hazard of death...
  13. ncbi request reprint Genetic variability in responses to caloric restriction in animals and in regulation of metabolism and obesity in humans
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York City, NY 10025, USA
    J Gerontol A Biol Sci Med Sci 56:55-65. 2001
    ..In addition, the panel emphasized several macro-level recommendations regarding research strategies to avoid, research strategies to emphasize, and resources needing development...
  14. ncbi request reprint The distribution of body mass index among individuals with and without schizophrenia
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    J Clin Psychiatry 60:215-20. 1999
    ....
  15. pmc Transmission-disequilibrium tests for quantitative traits
    D B Allison
    Obesity Research Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Hum Genet 60:676-90. 1997
    ..0001 alpha level with <300 observations...
  16. ncbi request reprint On estimating the minima of BMI-mortality curves
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Int J Obes Relat Metab Disord 20:496-8. 1996
    ..However, Waaler (1984)8 has argued that this approach systematically overestimates the optimal BMI because the true curve might not be quadratic. The purpose of this study was to test this proposition...
  17. ncbi request reprint A proposed heuristic for communicating heritability estimates to the general public, with obesity as an example
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Behav Genet 27:441-5. 1997
    ..The resulting statistic may prove useful for lay audiences in understanding a heritability estimate...
  18. ncbi request reprint Obesity among African American women: prevalence, consequences, causes, and developing research
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Womens Health 3:243-74. 1997
    ..The reasons for the very high prevalence of obesity among African American women are unknown. Data supporting various putative genetic, physiological, and psychosocial influences are discussed...
  19. pmc Meta-analysis of linkage data under worst-case conditions: a demonstration using the human OB region
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Genetics 148:859-65. 1998
    ..By applying these techniques to the literature on linkage in the human OB gene region, we are able to show that the evidence for linkage somewhere in the region is extremely strong (P = 1.5 x 10[-5])...
  20. ncbi request reprint Selected methodological issues in meiotic mapping of obesity genes in humans: issues of power and efficiency
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, New York, New York 10025, USA
    Behav Genet 27:401-21. 1997
    ..Finally, we advocate data pooling techniques (e.g., meta-analysis) to enhance the power and efficiency of the entire field of the genetics of obesity...
  21. ncbi request reprint The heritability of body mass index among an international sample of monozygotic twins reared apart
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University, College of Physicians and Surgeons, NY 10025, USA
    Int J Obes Relat Metab Disord 20:501-6. 1996
    ..Published heritability estimates (h2) for body mass index (BMI) range from as low as 0.05 to as high as 0.90. The purpose of this paper is to introduce new data to help narrow the range of plausible estimates...
  22. ncbi request reprint Method and computer program for controlling the family-wise alpha rate in gene association studies involving multiple phenotypes
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Genet Epidemiol 15:87-101. 1998
    ..e., AA, Aa, aa) implies by the closure principle that, after detection of a significant result for a specific variable, pairwise comparisons for that variable can be conducted without further adjustment of the alpha level...
  23. ncbi request reprint Extreme selection strategies in gene mapping studies of oligogenic quantitative traits do not always increase power
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, N Y, USA
    Hum Hered 48:97-107. 1998
    ..The 'optimal' sampling scheme may depend on both what one suspects the underlying genetic architecture to be and which of the oligogenic QTL one has greatest interest in detecting...
  24. ncbi request reprint The use of discordant sibling pairs for finding genetic loci linked to obesity: practical considerations
    D B Allison
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, NY 10025, USA
    Int J Obes Relat Metab Disord 20:553-60. 1996
    ..In this paper, I consider both of these issues...
  25. ncbi request reprint A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference
    M Heo
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Int J Obes Relat Metab Disord 26:640-6. 2002
    ....
  26. ncbi request reprint Sexual dimorphism in the energy content of weight change
    A Pietrobelli
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University Institute of Human Nutrition, College of Physicians and Surgeons, New York, USA
    Int J Obes Relat Metab Disord 26:1339-48. 2002
    ..The energy content of weight change is assumed to be sex- and age-neutral at 3,500 kcal/pound or 32.2 MJ/kg...
  27. pmc Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity
    M Heo
    New York Obesity Research Center, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Genetics 159:1163-78. 2001
    ..Although certain genotypic effects could be population specific, there was no statistically compelling evidence that any of the three LEPR alleles is associated with BMI or waist circumference in the general population...
  28. ncbi request reprint Association of K121Q polymorphism in ENPP1 (PC-1) with BMI in Caucasian and African-American adults
    N Matsuoka
    Division of Molecular Genetics, Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Int J Obes (Lond) 30:233-7. 2006
    ....
  29. ncbi request reprint Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial
    S B Heymsfield
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    JAMA 280:1596-600. 1998
    ..As a citrate cleavage enzyme that may play an essential role in de novo lipogenesis inhibition, G cambogia is claimed to lower body weight and reduce fat mass in humans...
  30. ncbi request reprint Relative influences of sex, race, environment, and HIV infection on body composition in adults
    D P Kotler
    Department of Medicine, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    Am J Clin Nutr 69:432-9. 1999
    ..The factors that control body composition in disease are uncertain...
  31. ncbi request reprint Antipsychotic-induced weight gain: a review of the literature
    D B Allison
    Obesity Research Center, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Clin Psychiatry 62:22-31. 2001
    ..As will be seen, this is an area of research in its infancy, and much work remains to be done...
  32. ncbi request reprint Putting the behavior into the behavior genetics of obesity
    M S Faith
    Obesity Research Center, St Luke s Roosevelt Hospital, New York, New York 10025, USA
    Behav Genet 27:423-39. 1997
    ..Fourth, a commentary on the importance of gene-environment interactions is offered. Finally, suggestions for future research, including a list of possible "candidate environments" and "candidate intermediary behaviors," are offered...
  33. ncbi request reprint Effects of contingent television on physical activity and television viewing in obese children
    M S Faith
    Obesity Research Center, St Luke's-Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Pediatrics 107:1043-8. 2001
    ..68). CONCLUSIONS: Contingencies in the home environment can be arranged to modify physical activity and TV viewing and may have a role in treating childhood obesity. Contingent TV may be one method to help achieve this goal...
  34. ncbi request reprint Gender differences in the relationship between personality dimensions and relative body weight
    M S Faith
    Obesity Research Center, St Luke s Roosevelt Hospital Center, Columbia University College of Physicians and Surgeons, New York, New York 10025, USA
    Obes Res 9:647-50. 2001
    ..We tested the association of BMI with neuroticism, extraversion, and psychoticism with a trimmed BMI sample...
  35. ncbi request reprint Is obesity a disease?
    S Heshka
    New York Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University Institute of Human Nutrition, New York 10025, USA
    Int J Obes Relat Metab Disord 25:1401-4. 2001
    ..However, neither writers who refer to obesity as a disease nor those who question whether it is a disease have generally provided a definition of disease and then offered evidence that obesity does or does not fit the definition...
  36. ncbi request reprint Glycemic effect of a single high oral dose of the novel sweetener sucralose in patients with diabetes
    N H Mezitis
    Division of Endocrinology, Diabetes and Nutrition, St Luke s Roosevelt Hospital Center, New York, NY 10025, USA
    Diabetes Care 19:1004-5. 1996
    ..To examine the effect of a single high oral dose of the novel noncaloric sweetener sucralose on short-term glucose homeostasis in patients with IDDM or NIDDM...
  37. ncbi request reprint Putative biases in estimating mortality attributable to obesity in the US population
    J A Greenberg
    Department of Health and Nutrition Sciences, Brooklyn College of the City University of New York, Brooklyn, NY, USA
    Int J Obes (Lond) 31:1449-55. 2007
    ..It is not presently known whether correcting for these biases would increase estimates of excess deaths attributable to obesity...
  38. ncbi request reprint Two novel quantitative trait loci on mouse chromosomes 6 and 4 independently and synergistically regulate plasma apoB levels
    C Ko
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Lipid Res 42:844-55. 2001
    ..The human orthologs for the Abrg loci are strong candidates for human disorders characterized by altered plasma apoB levels, such as FCHL and familial hypobetalipoproteinemia...