Juan M Alarcon

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene
    Juan M Alarcon
    College of Physicians and Surgeons of Columbia University, Columbia University, New York, New York 10032, USA
    Learn Mem 11:318-27. 2004
  2. ncbi Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture
    Angel Barco
    Center for Neurobiology and Behavior, Columbia University, 1051 Riverside Drive, New York, New York 10032, USA
    Neuron 48:123-37. 2005
  3. ncbi Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
    Juan M Alarcon
    Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Neuron 42:947-59. 2004
  4. ncbi Capture of the late phase of long-term potentiation within and across the apical and basilar dendritic compartments of CA1 pyramidal neurons: synaptic tagging is compartment restricted
    Juan M Alarcon
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Neurosci 26:256-64. 2006
  5. ncbi Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture
    Angel Barco
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Cell 108:689-703. 2002
  6. ncbi cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons
    Mikel Lopez de Armentia
    Instituto de Neurociencias de Alicante Universidad Miguel Hernández Consejo Superior de Investigaciones Científicas, Campus de Sant Joan, Sant Joan d Alacant, 03550 Alicante, Spain
    J Neurosci 27:13909-18. 2007
  7. ncbi Synapse-specific stabilization of plasticity processes: the synaptic tagging and capture hypothesis revisited 10 years later
    Angel Barco
    Instituto de Neurociencias de Alicante Universidad Miguel Hernández Consejo Superior de Investigaciones Científicas, Campus de Sant Joan Apt 18, Sant Joan d Alacant, 03550 Alicante, Spain
    Neurosci Biobehav Rev 32:831-51. 2008

Collaborators

Detail Information

Publications7

  1. ncbi Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene
    Juan M Alarcon
    College of Physicians and Surgeons of Columbia University, Columbia University, New York, New York 10032, USA
    Learn Mem 11:318-27. 2004
    ..These data suggest that CPEB-1 contributes in the translational control of mRNAs that is critical only for some selected forms of LTP and LTD...
  2. ncbi Gene expression profiling of facilitated L-LTP in VP16-CREB mice reveals that BDNF is critical for the maintenance of LTP and its synaptic capture
    Angel Barco
    Center for Neurobiology and Behavior, Columbia University, 1051 Riverside Drive, New York, New York 10032, USA
    Neuron 48:123-37. 2005
    ..We found that the overexpression of brain-derived neurotrophic factor accounts for an important component of this phenotype...
  3. ncbi Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration
    Juan M Alarcon
    Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Neuron 42:947-59. 2004
    ....
  4. ncbi Capture of the late phase of long-term potentiation within and across the apical and basilar dendritic compartments of CA1 pyramidal neurons: synaptic tagging is compartment restricted
    Juan M Alarcon
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    J Neurosci 26:256-64. 2006
    ..These results suggest that the tag appears specific to a compartment either apical or basilar and that an additional mechanism may be required to capture across compartments...
  5. ncbi Expression of constitutively active CREB protein facilitates the late phase of long-term potentiation by enhancing synaptic capture
    Angel Barco
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Cell 108:689-703. 2002
    ..Our analysis indicates that synaptic capture of CRE-driven gene products may be sufficient for consolidation of LTP and provides insight into the molecular mechanisms of synaptic tagging and synapse-specific potentiation...
  6. ncbi cAMP response element-binding protein-mediated gene expression increases the intrinsic excitability of CA1 pyramidal neurons
    Mikel Lopez de Armentia
    Instituto de Neurociencias de Alicante Universidad Miguel Hernández Consejo Superior de Investigaciones Científicas, Campus de Sant Joan, Sant Joan d Alacant, 03550 Alicante, Spain
    J Neurosci 27:13909-18. 2007
    ..As a result, our study has important implications for both the understanding of the cellular bases of learning and memory and the consideration of therapies targeted to the CREB pathway...
  7. ncbi Synapse-specific stabilization of plasticity processes: the synaptic tagging and capture hypothesis revisited 10 years later
    Angel Barco
    Instituto de Neurociencias de Alicante Universidad Miguel Hernández Consejo Superior de Investigaciones Científicas, Campus de Sant Joan Apt 18, Sant Joan d Alacant, 03550 Alicante, Spain
    Neurosci Biobehav Rev 32:831-51. 2008
    ..We will also discuss the impact of this model in our view of the integrative capability of neurons and associative learning...