Research Topics
Genomes and GenesSpecies | Habibul AhsanSummaryAffiliation: Columbia University Country: USA Publications
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Publications
Health Effects of Arsenic Longitudinal Study (HEALS): description of a multidisciplinary epidemiologic investigationHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Expo Sci Environ Epidemiol 16:191-205. 2006..HEALS is a valuable resource for examining novel research questions on the health effects of As exposure...- Arsenic exposure from drinking water and risk of premalignant skin lesions in Bangladesh: baseline results from the Health Effects of Arsenic Longitudinal StudyHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Epidemiol 163:1138-48. 2006..53, 5.44), and 5.39 (95% CI: 3.69, 7.86), respectively. The effect seemed to be influenced by gender, age, and body mass index. These findings provide information that should be considered in future research and policy decisions... - DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosisHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, Room 18 129, 622 West 168th Street, New York, NY 10032, USA
Toxicol Lett 143:123-31. 2003..Future larger studies are needed to confirm this novel finding and investigate how combinations of different candidate genes and/or other host and environmental factors may influence the risk of arsenic induced skin and other cancers... - Measures of genotype versus gene products: promise and pitfalls in cancer preventionHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA
Carcinogenesis 24:1429-34. 2003..Finally, we offer some specific recommendations for future research directions in this area... 
Association between arsenic exposure from drinking water and proteinuria: results from the Health Effects of Arsenic Longitudinal StudyYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, NY, USA
Int J Epidemiol 40:828-35. 2011..Proteinuria has been recognized as a marker for an increased risk of chronic renal disease. It is unclear whether arsenic (As) exposure from drinking water is associated with proteinuria...- Silencing of glutathione S-transferase P1 by promoter hypermethylation and its relationship to environmental chemical carcinogens in hepatocellular carcinomaYu Jing Zhang
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, 701 West 168th Street, New York, NY 10032, USA
Cancer Lett 221:135-43. 2005..The mechanism by which environmental exposures induce epigenetic changes in HCC needs further analysis... - Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in BangladeshHabibul Ahsan
Departments of Epidemiology, Columbia University, USA
Cancer Epidemiol Biomarkers Prev 16:1270-8. 2007.... 
Arsenic and manganese exposure and children's intellectual functionGail A Wasserman
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York City, NY 10032, USA
Neurotoxicology 32:450-7. 2011..25). Findings are consistent with other reports documenting adverse impact of both As and Mn exposure on child developmental outcomes, although associations appear muted at these relatively low exposure levels...- Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in BangladeshMary V Gamble
Departments of Environmental Health Sciences, Columbia University, New York, NY, USA
Am J Clin Nutr 84:1093-101. 2006..Consequently, folate nutritional status may influence arsenic methylation and toxicity... - Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adultsJ Richard Pilsner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue, B1, New York, NY 10032, USA
Am J Clin Nutr 86:1179-86. 2007..It is not known whether arsenic exposure influences genomic DNA methylation in human populations chronically exposed to arsenic-contaminated drinking water... - Folic acid supplementation lowers blood arsenicMary V Gamble
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Clin Nutr 86:1202-9. 2007..Methylation of ingested inorganic arsenic (InAs) to monomethylarsonic (MMAs) and dimethylarsinic (DMAs) acids relies on folate-dependent one-carbon metabolism and facilitates urinary arsenic elimination... 
Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, BangladeshGail A Wasserman
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Environ Health Perspect 115:285-9. 2007..We recently reported results of a cross-sectional investigation of intellectual function in 10-year-olds in Bangladesh, who had been exposed to arsenic from drinking water in their home wells...- Arsenic exposure at low-to-moderate levels and skin lesions, arsenic metabolism, neurological functions, and biomarkers for respiratory and cardiovascular diseases: review of recent findings from the Health Effects of Arsenic Longitudinal Study (HEALS) inYu Chen
Departments of Environmental Medicine and Medicine and New York University Cancer Institute, New York University School of Medicine, New York, NY, USA
Toxicol Appl Pharmacol 239:184-92. 2009.... - Urinary 15-F2t-isoprostane, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in TaiwanHui Chen Wu
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY 10032, USA
Carcinogenesis 29:971-6. 2008..These results suggest that elevated levels of urinary 15-F(2t)-IsoP may be related to increasing level of aflatoxin exposure and are associated with an increased risk of HCC... - Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in BangladeshMary V Gamble
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Environ Health Perspect 113:1683-8. 2005..This may be particularly relevant in Bangladesh, where the prevalence of hyperhomocysteinemia is extremely high... - Associations of plasma selenium with arsenic and genomic methylation of leukocyte DNA in BangladeshJ Richard Pilsner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 119:113-8. 2011..In addition, antagonism between As and Se, whereby each reduces toxicity of the other, has been well documented in animal models. Se status may therefore modify the health effects of As in As-exposed populations... - Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesionsMuhammad G Kibriya
Department of Epidemiology, Mailman School of Public Health, Columbia University, USA
Toxicol Lett 169:162-76. 2007..Additionally, this study suggests that long-term selenium supplementation may revert some of the gene expression changes presumably induced by chronic As exposure in individuals with pre-malignant skin lesions... - Consumption of folate-related nutrients and metabolism of arsenic in BangladeshJulia E Heck
Department of Epidemiology, Mailman School of Public Health and Institute for Social and Economic Research and Policy, Columbia University, New York, NY, USA
Am J Clin Nutr 85:1367-74. 2007..Previous studies suggest that persons with more complete methylation, characterized as greater proportions of DMA and lesser proportions of MMA and InAs in urine, have a lower risk of adverse arsenic-related health outcomes... - Influence of cobalamin on arsenic metabolism in BangladeshMegan N Hall
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 117:1724-9. 2009..Although DMA(V) is the least toxic metabolite, increasing evidence suggests that MMA(III) may be the most cytotoxic and genotoxic As intermediary metabolite... - Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNAYu Jing Zhang
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, New York 10032, USA
Clin Cancer Res 13:2378-84. 2007..We explored the possible diagnostic value of aberrant promoter hypermethylation of three tumor suppressor genes in serum DNA for early detection of HCC... - Betel quid chewing in rural Bangladesh: prevalence, predictors and relationship to blood pressureJulia E Heck
Department of Epidemiology, University of California, Los Angeles, CA, USA
Int J Epidemiol 41:462-71. 2012..The purpose of our study was to examine the prevalence and predictors of betel quid chewing in a rural area of Bangladesh, and determine its effects on body mass index (BMI) and blood pressure... - Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional studyYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Epidemiol 165:541-52. 2007..Future research is needed to evaluate the effect of low-level arsenic exposure on specific cardiovascular outcomes... - Polycyclic aromatic hydrocarbon- and aflatoxin-albumin adducts, hepatitis B virus infection and hepatocellular carcinoma in TaiwanHui Chen Wu
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY, USA
Cancer Lett 252:104-14. 2007..Environmental PAH exposure seems to enhance the hepatocarcinogenicity of chronic HBV infection... - Modification of risk of arsenic-induced skin lesions by sunlight exposure, smoking, and occupational exposures in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Epidemiology 17:459-67. 2006..Because most arsenic-induced skin cancers arise from these skin lesions, treatment and remediation plans should take into consideration these etiologic cofactors... - Effect of selenium and vitamin e supplementation on plasma protein carbonyl levels in patients with arsenic-related skin lesionsJulie Mahata
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
Nutr Cancer 60:55-60. 2008.... - Aflatoxin B1 exposure, hepatitis B virus infection, and hepatocellular carcinoma in TaiwanHui Chen Wu
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, 630 West 168th Street, RM19 418, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 18:846-53. 2009..However, in this larger study, the effect of combined AFB1 exposure and HBV infection is more consistent with an additive than a multiplicative model... - Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesionsJ Richard Pilsner
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Ave, B1, New York, NY 10032 USA
Environ Health Perspect 117:254-60. 2009..Clinical manifestations of As toxicity vary considerably among individuals and populations, and poor methylation capacity is thought to confer greater susceptibility... - Association between arsenic exposure from drinking water and plasma levels of soluble cell adhesion moleculesYu Chen
Departments of Environmental Medicine and Medicine, and New York University Cancer Institute, New York University School of Medicine, New York, New York 10016, USA
Environ Health Perspect 115:1415-20. 2007..Epidemiologic studies of cardiovascular disease risk factors and appropriate biomarkers in populations exposed to a wide range of arsenic levels are a public health research priority... - A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer riskKathryn E Talbott
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, 10032, USA
Breast Cancer Res Treat 111:481-7. 2008..The finding supports the potential role of variation in estrogen biosynthesis genes in premenopausal breast cancer risk... - Protective effects of B vitamins and antioxidants on the risk of arsenic-related skin lesions in BangladeshLydia B Zablotska
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 116:1056-62. 2008..The mitigating effects of diet on arsenic-related premalignant skin lesions are largely unknown... - Water manganese exposure and children's intellectual function in Araihazar, BangladeshGail A Wasserman
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, and New York State Psychiatric Institute, New York, New York 10032, USA
Environ Health Perspect 114:124-9. 2006..S. Environmental Protection Agency lifetime health advisory level. We conclude that in both Bangladesh and the United States, some children are at risk for Mn-induced neurotoxicity... - Aflatoxin B1 and polycyclic aromatic hydrocarbon adducts, p53 mutations and p16 methylation in liver tissue and plasma of hepatocellular carcinoma patientsYu Jing Zhang
Department of Environmental Health Science, Mailman School of Public Health of Columbia University, New York, NY 10032, USA
Int J Cancer 119:985-91. 2006..These data suggest that genetic, epigenetic and environmental exposure biomarkers in plasma may help in estimating the risk for the development of HCC... - Arsenic exposure and motor function among children in BangladeshFaruque Parvez
Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA
Environ Health Perspect 119:1665-70. 2011..Very little is known, however, about possible associations with other neurologic outcomes such as motor function... - Socioeconomic status and risk for arsenic-related skin lesions in BangladeshMaria Argos
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Public Health 97:825-31. 2007..In this study, we explored the association between socioeconomic status and arsenic toxicity... - Arsenic exposure from drinking water and mortality from cardiovascular disease in Bangladesh: prospective cohort studyYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, NY 10016, USA
BMJ 342:d2431. 2011..To evaluate the association between arsenic exposure and mortality from cardiovascular disease and to assess whether cigarette smoking influences the association... - Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation and its relationship to aflatoxin B1-DNA adducts and p53 mutation in hepatocellular carcinomaYu-Jing Zhang
Departments of Environmental Health Sciences and Epidemiology, Mailman School of Public Health, Columbia University, 700 West 168th Street, New York, NY 10032, USA
Int J Cancer 103:440-4. 2003..The role of chemical carcinogens in hypermethylation needs further investigation... - Urinary 8-oxodeoxyguanosine, aflatoxin B1 exposure and hepatitis B virus infection and hepatocellular carcinoma in TaiwanHui Chen Wu
Departments of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY 10032, USA
Carcinogenesis 28:995-9. 2007..These results suggest that elevated levels of urinary 8-oxodG may be related to increasing level of aflatoxin exposure but may also indicate enhanced repair of oxidative DNA damage and therefore lower risk of HCC... - Blood arsenic as a biomarker of arsenic exposure: results from a prospective studyMarni Hall
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University Medical Center, 60 Haven Avenue B1, New York, NY 10032, USA
Toxicology 225:225-33. 2006..This prospective study confirms the increased risk of skin lesions in relation to As concentrations in blood, urine and water and also establishes that BAs is a useful biomarker of As exposure in this study population... - Dietary intake of methionine, cysteine, and protein and urinary arsenic excretion in BangladeshJulia E Heck
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 117:99-104. 2009..Once ingested, arsenic is metabolized via methylation and excreted in urine. Knowledge about nutritional factors affecting individual variation in methylation is limited... - Do placental genes affect maternal breast cancer? Association between offspring's CGB5 and CSH1 gene variants and maternal breast cancer riskYu Chen
Department of Environmental Medicine, New York University Cancer Institute, New York University School of Medicine, New York, NY, USA
Cancer Res 68:9729-34. 2008..90; 95% CI, 0.53-1.51; P for interaction=0.04). The findings suggest that placental CGB5 genotype may be predictive of maternal post-pregnancy breast cancer risk among women who give birth early in life... - Arsenic exposure and anemia in Bangladesh: a population-based studyJulia E Heck
Department of Epidemiology, Mailman School of Public Health, College of Physicians and Surgeons, Columbia University, New York, NY, USA
J Occup Environ Med 50:80-7. 2008..The purpose of this study was to examine the association between arsenic exposure and anemia, based on blood hemoglobin concentration... - Prevalence of arsenic exposure from drinking water and awareness of its health risks in a Bangladeshi population: results from a large population-based studyFaruque Parvez
Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 114:355-9. 2006..Increasing knowledge of the health consequences of As may be an important element in facilitating remediation... - Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Environ Health Perspect 115:917-23. 2007..There is a need to identify and evaluate an effective mitigation program for arsenic exposure from drinking water in Bangladesh... - A prospective study of blood selenium levels and the risk of arsenic-related premalignant skin lesionsYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Cancer Epidemiol Biomarkers Prev 16:207-13. 2007..The findings support the hypothesis that dietary selenium intake may reduce the incidence of arsenic-related premalignant skin lesions among populations exposed to arsenic exposure from drinking water... - Association between arsenic exposure from drinking water and plasma levels of cardiovascular markersFen Wu
Department of Environmental Medicine, New York University School of Medicine, New York, USA
Am J Epidemiol 175:1252-61. 2012.... - Tremor severity and age: a cross-sectional, population-based study of 2,524 young and midlife normal adultsElan D Louis
GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Mov Disord 26:1515-20. 2011..These data suggest that age-dependent increase in tremor amplitude is not restricted to older people but occurs in all adult age groups... - Nutritional influence on risk of high blood pressure in Bangladesh: a population-based cross-sectional studyYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
Am J Clin Nutr 84:1224-32. 2006..The nutritional determinants of hypertension in Bangladesh and other low-income countries are largely unknown... - A prospective study of respiratory symptoms associated with chronic arsenic exposure in Bangladesh: findings from the Health Effects of Arsenic Longitudinal Study (HEALS)Faruque Parvez
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
Thorax 65:528-33. 2010..A total of 7.31, 9.95 and 2.03% of the 11 746 participants completing 4 years of active follow-up reported having a chronic cough, breathing problem or blood in their sputum, respectively, as assessed by trained physicians... - Estrogen-biosynthesis gene CYP17 and its interactions with reproductive, hormonal and lifestyle factors in breast cancer risk: results from the Long Island Breast Cancer Study ProjectYu Chen
Department of Environmental Medicine and New York University Cancer Institute, New York University School of Medicine, New York, NY 10016, USA
Carcinogenesis 29:766-71. 2008..In conclusion, the findings suggest that the CYP17 variant C allele may increase breast cancer risk in conjunction with long-term HRT use and high BMI in postmenopausal women... - Arsenic exposure from drinking water and dyspnoea risk in Araihazar, Bangladesh: a population-based studyGene R Pesola
Division of Pulmonary and Critical Care Medicine, Dept of Medicine, Harlem Hospital, Columbia University, New York, NY 10037, USA
Eur Respir J 39:1076-83. 2012..This study suggests that mandated well water testing for arsenic with reduction in exposure may significantly reduce diseases that manifest as dyspnoea, usually cardiac or pulmonary... - Prevalence of essential tremor in Araihazar, Bangladesh: a population-based studyElan D Louis
GH Sergievsky Center, Columbia University, New York, NY, USA EDL2 columbia edu
Neuroepidemiology 36:71-6. 2011..Few prevalence studies have been conducted in South Asia, and none in Bangladesh, one of the most populated countries in the world. We estimated the prevalence of ET in a population-based study in Araihazar, Bangladesh... - High frequency of promoter hypermethylation of RASSF1A and p16 and its relationship to aflatoxin B1-DNA adduct levels in human hepatocellular carcinomaYu-Jing Zhang
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, New York 10032, USA
Mol Carcinog 35:85-92. 2002..No association was found between methylation status and p53 status. These results suggest the hypothesis that exposure to environmental carcinogens may be involved in altered methylation of genes involved in cancer development... - Arsenic exposure from drinking-water and carotid artery intima-medial thickness in healthy young adults in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, 10032, USA
J Health Popul Nutr 24:253-7. 2006.... - Susceptibility to arsenic-induced hyperkeratosis and oxidative stress genes myeloperoxidase and catalaseHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columfbia University, Room 720G, 722 West 168th Street, New York, NY 10032, USA
Cancer Lett 201:57-65. 2003..Our findings, although based on small numbers, suggest that the oxidative stress genes MPO and CAT may influence the risk of arsenic-induced premalignant hyperkeratotic skin lesions... - Protein and amino acid intakes in a rural area of BangladeshJulia E Heck
Department of Epidemiology, Columbia University, New York, USA
Food Nutr Bull 31:206-13. 2010..Few studies have described protein and amino acid intakes in rural Bangladesh, a country with considerable undernutrition... - Variants in estrogen metabolism and biosynthesis genes and urinary estrogen metabolites in women with a family history of breast cancerHeather Greenlee
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 West 168th Street, 7th Floor, New York, NY 10032, USA
Breast Cancer Res Treat 102:111-7. 2007.... - Variants in estrogen-biosynthesis genes CYP17 and CYP19 and breast cancer risk: a family-based genetic association studyHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
Breast Cancer Res 7:R71-81. 2005.... - Water arsenic exposure and children's intellectual function in Araihazar, BangladeshGail A Wasserman
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Environ Health Perspect 112:1329-33. 2004..5 microg/L. The association was generally stronger for well-water As than for urinary As... - Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi populationMaria Argos
Department of Epidemiology, Mailman School of Public Health, Columbia University Medical Center, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 15:1367-75. 2006..Genes identified from this analysis may provide insights into the underlying processes of arsenic-induced disease and represent potential targets for chemoprevention studies to reduce arsenic-induced skin cancer in this population... - A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in BangladeshWendy J Verret
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Occup Environ Med 47:1026-35. 2005..CONCLUSIONS: Supplementation with vitamin E and selenium, either alone or in combination, slightly improved skin lesion status, although the improvement was not statistically significant... - Nonmalignant respiratory effects of chronic arsenic exposure from drinking water among never-smokers in BangladeshFaruque Parvez
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
Environ Health Perspect 116:190-5. 2008..The association with nonmalignant respiratory illnesses has not been well established because the assessments of respiratory symptoms may be influenced by recall bias or interviewer bias because participants had visible skin lesions... - Association between manganese exposure through drinking water and infant mortality in BangladeshDanella Hafeman
Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Environ Health Perspect 115:1107-12. 2007..In this cross-sectional study we assessed the association between water manganese and all-cause infant mortality in the offspring of female participants in the Health Effects of Arsenic Longitudinal Study Cohort... - Evaluation of 4-aminobiphenyl-DNA adducts in human breast cancer: the influence of tobacco smokeBeatrice Faraglia
Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 701 West 168th Street, New York, NY 10032, USA
Carcinogenesis 24:719-25. 2003..In this study, genetic polymorphisms did not significantly affect the formation of 4-ABP-DNA adducts in breast cancer cases, perhaps due to the small number of samples... - No association between arsenic exposure from drinking water and diabetes mellitus: a cross-sectional study in BangladeshYu Chen
Department of Environmental Medicine, New York University School of Medicine, New York, New York, USA
Environ Health Perspect 118:1299-305. 2010..The long-term effects of arsenic exposure from drinking water at levels < 300 microg/L and the risk of diabetes mellitus remains a controversial topic... - Folate and cobalamin deficiencies and hyperhomocysteinemia in BangladeshMary V Gamble
Department of Environmental Health Sciences, School of Public Health, Columbia University, New York, NY 10032, USA
Am J Clin Nutr 81:1372-7. 2005..This has been largely attributed to dietary deficiencies in cobalamin associated with vegetarianism among these Indian Asians... - Cancer screening practices of Asian American physicians in New York CityEthan E Bodle
Asian American Network for Cancer Awareness, Research, and Training, Mailman School of Public Health, Columbia University, New York, NY, USA
J Immigr Minor Health 10:239-46. 2008..About 70% recommend screening for hepatitis B. Gender and ethnicity of the physician were found to be significant predictors for cancer screening practice... - Association between arsenic exposure and a measure of subclinical sensory neuropathy in BangladeshDanella M Hafeman
Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Occup Environ Med 47:778-84. 2005..02 and P = 0.009, respectively) after adjustment for age and gender. CONCLUSIONS: Increased arsenic exposure, as measured by both cumulative and urinary measures, was associated with evidence of subclinical sensory neuropathy... - A family-based genetic association study of variants in estrogen-metabolism genes COMT and CYP1B1 and breast cancer riskHabibul Ahsan
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Breast Cancer Res Treat 85:121-31. 2004.... - Polycyclic aromatic hydrocarbon-DNA adducts in liver tissues of hepatocellular carcinoma patients and controlsShu Yuan Chen
Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, New York, NY 10032, USA
Int J Cancer 99:14-21. 2002..2-187.2) compared to those who had low DNA adduct levels. These results suggest that PAHs may play a role in human hepatocarcinogenesis in conjunction with HBsAg carrier status, GSTM1 and GSTP1 genotypes and exposure to 4-ABP and AFB(1)... - Cancer burden from arsenic in drinking water in BangladeshYu Chen
Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 W. 168th Street, New York, NY 10032, USA
Am J Public Health 94:741-4. 2004..Results indicated at least a doubling of lifetime mortality risk from liver, bladder, and lung cancers (229.6 vs 103.5 per 100 000 population) in Bangladesh owing to arsenic in drinking water... - Placental genes and breast cancer: can the offspring's or father's genotypes predict mother's risk?Habibul Ahsan
Department of Epidemiology, Mailman School of Public Health and Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY 10032, USA
Epidemiology 14:251-3. 2003.... - Relative risk for genetic associations: the case-parent triad as a variant of case-cohort designHabibul Ahsan
Department of Epidemiology, Joseph L Mailman School of Public Health, New York, NY, USA
Int J Epidemiol 31:669-78. 2002..Also, by allowing the potential sources of selection bias to be revealed more easily the design is made more accessible both conceptually and practically to epidemiologists... - Further development of the case-only design for assessing gene-environment interaction: evaluation of and adjustment for biasNicolle M Gatto
Department of Epidemiology, Mailman School of Public Health at Columbia University in the City of New York, NY, USA
Int J Epidemiol 33:1014-24. 2004..Given that control for non-independence is possible when the source of the non-independence can be conceptualized, the case-only design may still be a useful epidemiological tool for examining gene-environment interactions... - Predicting asthma morbidity in Harlem emergency department patientsGene R Pesola
Harlem Lung Center and Hospital Emergency Department, Columbia University, New York, NY, USA
Acad Emerg Med 11:944-50. 2004..To determine predictors of asthma morbidity in African American patients with asthma. Proxies for asthma morbidity were emergency department (ED) visits for asthma and hospitalizations for asthma... - Dyspnea reproducibility in a rural Bangladesh populationGene Raymond Pesola
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Harlem Hospital Center, Columbia University, New York, NY 10037, USA
Clin Respir J 3:222-8. 2009..Dyspnea screening would only be valid if reproducible. The study aim was to determine the reliability (reproducibility) of assessing dyspnea through a simple questionnaire among a rural population... - Methods for assessing familial aggregation: family history measures and confounding in the standard cohort, reconstructed cohort and case-control designsRegina Zimmerman
Department of Epidemiology, Mailman School of Public Health, New York, NY, USA
Hum Hered 68:201-8. 2009..In addition, we test if the definition of family history affects the accuracy of results obtained from either design. We use simulated data, which allows us to know the true data origin... - Promotion of well-switching to mitigate the current arsenic crisis in BangladeshAlexander van Geen
Lamont Doherty Earth Observatory, Columbia University, Palisades, New York 10964, USA
Bull World Health Organ 80:732-7. 2002..To survey tube wells and households in Araihazar upazila, Bangladesh, to set the stage for a long-term epidemiological study of the consequences of chronic arsenic exposure... - New York AANCART: using participatory research to address the health needs of South Asian and Korean Americans in New York CityNadia Islam
Center for the Study of Asian American Health, New York University School of Medicine, New York, New York 10032, USA
Cancer 104:2931-6. 2005..Using case studies from two community-based partnerships that were developed by NY AANCART, the current report describes how the principles of CBPR were applied in two rapidly growing Asian-American communities in New York City... - Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer riskVirginia G Kaklamani
Cancer Genetics Program, Division of Hematology Oncology, Department of Medicine, Feinberg School of Medicine and Robert H Lurie Comprehensive Cancer Center, Northwestern University, 676 North St Clair Street, Chicago, IL 60611, USA
Cancer Res 65:3454-61. 2005..25-3.87). This is the first study assessing the TGF-beta signaling pathway through two common and functionally relevant TGFBR1 and TGFB1 variants. This approach may predict breast cancer risk in a large subset of the population... - Covariate adjustment in family-based association studiesAlice S Whittemore
Division of Epidemiology, Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California, USA
Genet Epidemiol 28:244-55. 2005..e., data for which multiple logistic regression of matched sibships would have little power. Software for performing the covariate-adjusted tests is available at http://www.stanford.edu/dept/HRP/epidemiology/COVTDT... - Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer riskVirginia G Kaklamani
Division of Hematology Oncology, Department of Medicine, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Cancer Res 68:3178-84. 2008..89; P(trend) = 0.001). This is the first report of an association between functionally relevant variants of the adiponectin pathway and breast cancer risk. The results warrant further studies of the adiponectin pathway in breast cancer... - Design options for molecular epidemiology research within cohort studiesAndrew G Rundle
Department of Epidemiology, Mailman School of Public Health and Herbert Irving Comprehensive Cancer Center, Columbia University, 722 West 168th, Room 730, New York, NY 10032, USA
Cancer Epidemiol Biomarkers Prev 14:1899-907. 2005..However, in total, of the two designs, the nested case-control study is better suited for studying biomarkers that can be influenced by analytic batch, long-term storage, and freeze-thaw cycles... - Polycyclic aromatic hydrocarbon-DNA adducts among rickshaw drivers in Dhaka City, BangladeshM Hafizur Rahman
Department of Biochemistry, Bangabandhu Sheikh Mujib Medical University (BSMMU, Dhaka, Bangladesh
Int Arch Occup Environ Health 76:533-8. 2003..In conclusion, the results suggest that urban residents who are occupationally exposed to traffic pollution in Dhaka are at potentially higher risk of health effects from exposure to carcinogenic PAH compounds... - Preferential distal radius fracture in right-handed individuals presenting to an EDGene R Pesola
Department of Emergency Medicine, St Vincent s Hospital, Academic Medical Center of New York Medical College, New York, NY, USA
Am J Emerg Med 21:552-5. 2003..If this data holds up, finding the etiology/mechanism of this predisposition might help in designing environments to minimize the impact of this injury pattern in the slightly older individual...