William C Adams

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. doi request reprint Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein
    William C Adams
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Gen Virol 93:1339-44. 2012
  2. pmc IFN-α produced by human plasmacytoid dendritic cells enhances T cell-dependent naïve B cell differentiation
    Cornelia Gujer
    Center for Infectious Medicine, Karolinska Institutet, Stockholm, Sweden
    J Leukoc Biol 89:811-21. 2011
  3. doi request reprint Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation
    Kerrie J Sandgren
    Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 141 86 Stockholm, Sweden
    J Immunol 191:60-9. 2013
  4. pmc Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation
    William C Adams
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 108:7499-504. 2011
  5. pmc Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations
    Emily Bond
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 132:114-23. 2012
  6. doi request reprint Human B cell responses to TLR ligands are differentially modulated by myeloid and plasmacytoid dendritic cells
    Iyadh Douagi
    Swedish Institute for Infectious Disease Control, Stockholm, Sweden
    J Immunol 182:1991-2001. 2009
  7. doi request reprint AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment
    Evelina Lindmark
    Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Autoimmun 42:62-70. 2013
  8. doi request reprint In vitro stimulation and detection of IFNα production in human plasmacytoid dendritic cells
    William C Adams
    Department of Medicine, Center for Infectious Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Methods Mol Biol 820:215-30. 2012
  9. doi request reprint Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN
    William C Adams
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Gen Virol 90:1600-10. 2009
  10. pmc The Toxoplasma gondii-shuttling function of dendritic cells is linked to the parasite genotype
    Henrik Lambert
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, SE 14186 Stockholm, Sweden
    Infect Immun 77:1679-88. 2009

Collaborators

Detail Information

Publications10

  1. doi request reprint Attenuation of CD4+ T-cell function by human adenovirus type 35 is mediated by the knob protein
    William C Adams
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Gen Virol 93:1339-44. 2012
    ..Thus, the capacity of HAdV-35 to attenuate human CD4(+) T-cell activation depends predominantly on knob interactions with CD46 and can occur independently of infection...
  2. pmc IFN-α produced by human plasmacytoid dendritic cells enhances T cell-dependent naïve B cell differentiation
    Cornelia Gujer
    Center for Infectious Medicine, Karolinska Institutet, Stockholm, Sweden
    J Leukoc Biol 89:811-21. 2011
    ..In summary, PDCs, via their production of IFN-α, may render B cells more responsive to T cell contact, which in turn, facilitates B cell proliferation and differentiation to antibody-producing cells...
  3. doi request reprint Human plasmacytoid dendritic cells efficiently capture HIV-1 envelope glycoproteins via CD4 for antigen presentation
    Kerrie J Sandgren
    Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, 141 86 Stockholm, Sweden
    J Immunol 191:60-9. 2013
    ....
  4. pmc Adenovirus type-35 vectors block human CD4+ T-cell activation via CD46 ligation
    William C Adams
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 108:7499-504. 2011
    ..Our findings provide insights into the basic biology of adenoviruses and indicate that CD46 binding may have an impact on the generation of primary CD4(+) T-cell responses by Ad35...
  5. pmc Plasmacytoid dendritic cells infiltrate the skin in positive tuberculin skin test indurations
    Emily Bond
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 132:114-23. 2012
    ....
  6. doi request reprint Human B cell responses to TLR ligands are differentially modulated by myeloid and plasmacytoid dendritic cells
    Iyadh Douagi
    Swedish Institute for Infectious Disease Control, Stockholm, Sweden
    J Immunol 182:1991-2001. 2009
    ..These data help decipher the different roles of PDCs and MDCs for modulating human B cell responses and can contribute to selection of specific TLR ligands as vaccine adjuvants...
  7. doi request reprint AIRE expressing marginal zone dendritic cells balances adaptive immunity and T-follicular helper cell recruitment
    Evelina Lindmark
    Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Solna, SE 171 76 Stockholm, Sweden
    J Autoimmun 42:62-70. 2013
    ....
  8. doi request reprint In vitro stimulation and detection of IFNα production in human plasmacytoid dendritic cells
    William C Adams
    Department of Medicine, Center for Infectious Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Methods Mol Biol 820:215-30. 2012
    ..We discuss the key elements for successful isolation of PDCs, stimulation, immunostaining, and identification of IFNα producing cells...
  9. doi request reprint Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN
    William C Adams
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Gen Virol 90:1600-10. 2009
    ..A better understanding of the tropism and receptor mechanisms of Ad5 may help explain Ad5 pathogenesis and guide the engineering of improved rAd vectors...
  10. pmc The Toxoplasma gondii-shuttling function of dendritic cells is linked to the parasite genotype
    Henrik Lambert
    Center for Infectious Medicine, Department of Medicine, Karolinska Institutet, SE 14186 Stockholm, Sweden
    Infect Immun 77:1679-88. 2009
    ....