E J Abrams
Affiliation: Columbia University
- Systemic delays in the initiation of antiretroviral therapy during pregnancy do not improve outcomes of HIV-positive mothers: a cohort studyLandon Myer
Centre for Infectious Diseases Epidemiologic Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa
BMC Pregnancy Childbirth 12:94. 2012..We examined whether delaying ART to provide pre-ART counseling was associated with improved outcomes among HIV-infected women in Cape Town, South Africa...
- Can we achieve an AIDS-free generation? Perspectives on the global campaign to eliminate new pediatric HIV infectionsElaine J Abrams
ICAP, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Acquir Immune Defic Syndr 63:S208-12. 2013....
- PEPFAR scale-up of pediatric HIV services: innovations, achievements, and challengesElaine J Abrams
ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA
J Acquir Immune Defic Syndr 60:S105-12. 2012....
- Adherence and virologic suppression during the first 24 weeks on antiretroviral therapy among women in Johannesburg, South Africa - a prospective cohort studyZiad El-Khatib
Nordic School of Public Health NHV, Gothenburg, Sweden
BMC Public Health 11:88. 2011..We assessed risk factors for incomplete adherence among a cohort of HIV-infected women initiating ART and examined associations between adherence and virologic response to ART...
- Incidence and risk factors of severe adverse events with nevirapine-based antiretroviral therapy in HIV-infected women. MTCT-Plus program, Abidjan, Côte d'IvoirePatrick A Coffie
Programme MTCT Plus, ACONDA, BP 1954 Abidjan 18, Abidjan, Cote d Ivoire
BMC Infect Dis 10:188. 2010..We estimated the incidence of SAEs according to CD4 cell count and identify their risk factors in nevirapine-treated women...
- Population genetic estimation of the loss of genetic diversity during horizontal transmission of HIV-1Charles T T Edwards
Nuffield Department of Clinical Medicine, University of Oxford, The Peter Medawar Building for Pathogen Research, Oxford, OX1 3SY, UK
BMC Evol Biol 6:28. 2006..Despite this, the magnitude of this population bottleneck is unclear...
- Lessons from Harlem: Relevance to a global epidemicElaine J Abrams
Department of Pediatrics, Harlem Hospital, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Acquir Immune Defic Syndr 52:S24-6. 2009..Lessons learned from this effort have been applied to other health threats in the community and could inform the global response to HIV...
- Should treatment be started among all HIV-infected children and then stopped?Elaine J Abrams
Columbia University, New York City NY, USA
Lancet 362:1595-6. 2003
- Prevention of mother-to-child transmission of HIV--successes, controversies and critical questionsElaine J Abrams
College of Physicians and Surgeons, Columbia University New York City, New York, USA
AIDS Rev 6:131-43. 2004..While work must continue to identify more efficacious and safe regimens to prevent MTCT, preventing women from becoming HIV-infected should remain the true measure of success...
- Prevention of mother-to-child transmission services as a gateway to family-based human immunodeficiency virus care and treatment in resource-limited settings: rationale and international experiencesElaine J Abrams
International Center for HIV AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
Am J Obstet Gynecol 197:S101-6. 2007....
- Aging cohort of perinatally human immunodeficiency virus-infected children in New York City. New York City Pediatric Surveillance of Disease ConsortiumE J Abrams
Harlem Hospital Center, Columbia University, College of Physicians and Surgeons, New York, NY, USA
Pediatr Infect Dis J 20:511-7. 2001..New York City (NYC) pediatricians are now caring for fewer HIV-infected infants and more school age children and adolescents than earlier in the epidemic...
- Opportunistic infections and other clinical manifestations of HIV disease in childrenE J Abrams
Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, USA
Pediatr Clin North Am 47:79-108. 2000..The prophylaxis, diagnosis, and treatment of opportunistic infections are likely to remain integral components of HIV care for the near and distant future...
- Association of human immunodeficiency virus (HIV) load early in life with disease progression among HIV-infected infants. New York City Perinatal HIV Transmission Collaborative Study GroupE J Abrams
Harlem Hospital Center, New York, New York 10037, USA
J Infect Dis 178:101-8. 1998..002) during the first 18 months of life. Except for values from the first week of life, virus load at any age through 18 months is strongly associated with risk of HIV disease progression...
- Distinct risk factors for intrauterine and intrapartum human immunodeficiency virus transmission and consequences for disease progression in infected children. Perinatal AIDS Collaborative Transmission StudyL Kuhn
Columbia University, Medical and Health Research Association Inc, Harlem Hospital Center, New York, USA
J Infect Dis 179:52-8. 1999..Preterm infants may be more vulnerable to HIV acquisition at delivery, especially if membrane rupture is prolonged. Intrauterine infection does not appear to increase risk of preterm delivery...
- Disease progression and early viral dynamics in human immunodeficiency virus-infected children exposed to zidovudine during prenatal and perinatal periodsL Kuhn
Columbia University, Sergievsky Center, New York, NY 10032, USA
J Infect Dis 182:104-11. 2000..More rapid disease progression was observed among infected children exposed during pregnancy or birth to Zdv if effective multidrug therapy was not initiated...
- Maternal health factors and early pediatric antiretroviral therapy influence the rate of perinatal HIV-1 disease progression in childrenElaine J Abrams
Harlem Hospital Center and Columbia University, College of Physicians and Surgeons, New York, New York 10037, USA
AIDS 17:867-77. 2003..To determine the relationship of maternal health factors and infant antiretroviral treatment to the risk of pediatric disease progression to AIDS or death by 24 months of age...
- The role of psychosocial and family factors in adherence to antiretroviral treatment in human immunodeficiency virus-infected childrenClaude Ann Mellins
HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, and Columbia University, College of Physicians and Surgeons, New York, NY, USA
Pediatr Infect Dis J 23:1035-41. 2004..This study examines child psychosocial and caregiver/family factors influencing adherence to ART in perinatally human immunodeficiency virus (HIV)-infected children...
- Antiretroviral resistance mutations among pregnant human immunodeficiency virus type 1-infected women and their newborns in the United States: vertical transmission and cladesP Palumbo
Department of Pediatrics, University of Medicine and Dentistry of New Jersey New Jersey Medical School, 185 S Orange Ave, Newark, NJ 07103, USA
J Infect Dis 184:1120-6. 2001..Although no effect of viral resistance on mother-infant transmission was demonstrated, the advent of more-potent drug classes and the potential for the rapid emergence of resistance warrant prospective surveillance...
- Family experiences with pediatric antiretroviral therapy: responsibilities, barriers, and strategies for remembering medicationsStephanie L Marhefka
HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University of the City of New York, New York, New York, USA
AIDS Patient Care STDS 22:637-47. 2008..More intensive interventions, such as home-based nurse-administered dosing, may be necessary...
- Trends in perinatal HIV prevention in New York City, 1994-2003Vicki B Peters
HIV Epidemiology and Field Services Program, New York City Department of Health and Mental Hygiene, 346 Broadway, Room 706, New York, NY 10013, USA
Am J Public Health 98:1857-64. 2008..We examined trends in perinatal HIV prevention interventions in New York City implemented during 1994 to 2003 to ascertain the success of the interventions in reducing perinatal transmission...
- Scale-up of HIV care and treatment: can it transform healthcare services in resource-limited settings?Wafaa M El-Sadr
International Center for AIDS Care and Treatment Programs, Columbia University Mailman School of Public Health, New York, New York 10032, USA
AIDS 21:S65-70. 2007..In order to determine these broader effects, mechanisms need to be established that enable relevant research and evaluation questions to be answered...
- Brief report: language ability and school functioning of youth perinatally infected with HIVElizabeth Brackis-Cott
HIV Center for Clinical and Behavioral Studies New York State, Psychiatric Institute Unit 15, 1051 Riverside Dr, New York, NY 10032, USA
J Pediatr Health Care 23:158-64. 2009..The purpose of this article is to describe the language ability and school functioning of early adolescents with perinatal HIV/AIDS...
- Effect of bimonthly supplementation with oral cholecalciferol on serum 25-hydroxyvitamin D concentrations in HIV-infected children and adolescentsStephen M Arpadi
Sergievsky Center, College of Physicians and Surgeons, New York, NY 10032, USA
Pediatrics 123:e121-6. 2009....
- Rates and types of psychiatric disorders in perinatally human immunodeficiency virus-infected youth and serorevertersClaude Ann Mellins
HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, New York 10032, USA
J Child Psychol Psychiatry 50:1131-8. 2009....
- Mental health in youth infected with and affected by HIV: the role of caregiver HIVKatherine S Elkington
HIV Center for Clinical and Behavioral Sciences, Columbia University and New York State Psychiatric Institute, 1051 Riverside Drive 15, New York, NY 10032, USA
J Pediatr Psychol 36:360-73. 2011..To examine the association of youth and caregiver HIV status, and other contextual and social regulation factors with youth mental health...
- The impact of perinatal HIV infection on older school-aged children's and adolescents' receptive language and word recognition skillsElizabeth Brackis-Cott
HIV Center for Clinical and Behavioral Studies at New York State Psychiatric Institute and Columbia University, New York, New York 10032, USA
AIDS Patient Care STDS 23:415-21. 2009..Findings highlight poor language ability among youths infected with and affected by HIV, and the importance of educational interventions that address this emerging need...
- Immune reconstitution inflammatory syndrome among HIV-infected South African infants initiating antiretroviral therapyKelly Smith
Columbia University College of Physicians and Surgeons, New York, New York, USA
AIDS 23:1097-107. 2009..To determine the incidence, clinical manifestations and risk factors for immune reconstitution inflammatory syndrome (IRIS) in young children initiating highly active antiretroviral therapy (HAART)...
- Sexual and drug use behavior in perinatally HIV-infected youth: mental health and family influencesClaude A Mellins
HIV Center for Clinical and Behavioral Studies, Columbia University and New York State Psychiatric Institute, New York, NY, USA
J Am Acad Child Adolesc Psychiatry 48:810-9. 2009....
- CD4+ cell count testing more effective than HIV disease clinical staging in identifying pregnant and postpartum women eligible for antiretroviral therapy in resource-limited settingsRosalind J Carter
International Center for AIDS Care and Treatment Programs, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
J Acquir Immune Defic Syndr 55:404-10. 2010..However, there have been few investigations of the performance of ART eligibility criteria in pregnant and postpartum women in resource-limited settings...
- Initiation of antiretroviral therapy among pregnant women in resource-limited countries: CD4+ cell count response and program retentionPatricia L Toro
International Center for AIDS Care and Treatment Programs, Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA
AIDS 24:515-24. 2010..Few data are available from resource-limited countries on long-term outcomes of HIV-infected women who initiate antiretroviral therapy (ART) during pregnancy...
- HIV treatment-related knowledge and self-efficacy among caregivers of HIV-infected childrenOuzama Nicholson
HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, Columbia University, Box 15, 1051 Riverside Drive, New York, NY 10032, USA
Patient Educ Couns 61:405-10. 2006..We examined whether caregivers' knowledge and self-efficacy was associated with better clinical outcomes and anti-retroviral therapy (ART) adherence among HIV-infected children...
- The reliability of reports of medical adherence from children with HIV and their adult caregiversCurtis Dolezal
New York State Psychiatric Institute, 1051 Riverside Drive, Unit 15, New York, New York 10032, USA
J Pediatr Psychol 28:355-61. 2003..To compare children's reports of their medication adherence to those of their adult caregivers...
- Dyslipidemia among perinatally HIV-infected children enrolled in the PACTS-HOPE cohort, 1999-2004: a longitudinal analysisRosalind J Carter
Medical and Health Research Association, New York, NY 10032, USA
J Acquir Immune Defic Syndr 41:453-60. 2006..Protease inhibitor (PI)-containing regimens have led to improved survival among HIV-infected children. However, adverse effects, including dyslipidemia, may put children at risk for cardiovascular disease...
- Focus on women: linking HIV care and treatment with reproductive health services in the MTCT-Plus InitiativeLandon Myer
Columbia University, Mailman School of Public Health, New York, NY, USA
Reprod Health Matters 13:136-46. 2005....
- Progressive multifocal leukoencephalopathy successfully treated with highly active antiretroviral therapy and cidofovir in an adolescent infected with perinatal human immunodeficiency virus (HIV)Lisa Gaye Robinson
Department of Pediatrics, College of Physicians and Surgeons, Columbia University, Harlem Hospital Center, New York, New York 10025, USA
J Child Neurol 19:35-8. 2004..We report a case of progressive multifocal leukoencephalopathy successfully treated with highly active antiretroviral therapy and cidofovir in an adolescent patient perinatally infected with human immunodeficiency virus (HIV)...
- Psychiatric disorders in youth with perinatally acquired human immunodeficiency virus infectionClaude Ann Mellins
HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute, and Columbia University, New York 10032, USA
Pediatr Infect Dis J 25:432-7. 2006..This pilot study explores rates and types of psychiatric and substance use disorders, as well as emotional and behavioral functioning in perinatally HIV-infected children and adolescents...
- Genital herpes simplex virus infection and perinatal transmission of human immunodeficiency virusKatherine T Chen
Department of Obstetrics and Gynecology, Columbia University, Sergievsky Center and Harlem Hospital Center, New York, New York 10032, USA
Obstet Gynecol 106:1341-8. 2005..To assess the risk of perinatal human immunodeficiency virus (HIV) transmission in HIV-infected women clinically diagnosed with genital herpes simplex virus (HSV) infection during pregnancy...
- Incidence and prevalence of HIV encephalopathy in children with HIV infection receiving highly active anti-retroviral therapy (HAART)Claudia A Chiriboga
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA
J Pediatr 146:402-7. 2005..To describe neurologic outcomes in children infected with HIV in the era of highly active anti-retroviral therapy (HAART), including rates of progressive HIV encephalopathy (PHE) and clinical sequelae among PHE survivors...
- Maternal versus paternal inheritance of HLA class I alleles among HIV-infected children: consequences for clinical disease progressionLouise Kuhn
Gertrude H Sergievsky Center, College of Physicians and Surgeons, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
AIDS 18:1281-9. 2004..We investigated whether maternal HLA selection pressures on the virus would adversely influence clinical outcomes of HIV-infected children...
- Initial response to protease-inhibitor-based antiretroviral therapy among children less than 2 years of age in South Africa: effect of cotreatment for tuberculosisCordula Reitz
Gertrude H Sergievsky Center and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City, New York 10032, USA
J Infect Dis 201:1121-31. 2010..We investigated factors associated with viral suppression and mortality among young children initiating ART...
- Impact of medications prescribed for treatment of attention-deficit hyperactivity disorder on physical growth in children and adolescents with HIVPatricia A Sirois
Department of Pediatrics, Tulane University School of Medicine, New Orleans, LA 70112, USA
J Dev Behav Pediatr 30:403-12. 2009..To examine the relationships between physical growth and medications prescribed for symptoms of attention-deficit hyperactivity disorder in children with HIV...
- Safety and immunogenicity of a heptavalent pneumococcal conjugate vaccine in infants with human immunodeficiency virus type 1 infectionSharon Nachman
Department of Pediatrics, State University of New York Health Science Center at Stony Brook, Stony Brook, New York 11794, USA
Pediatrics 112:66-73. 2003..This study was conducted to evaluate the safety and immunogenicity of heptavalent PCV in infants with HIV infection...
- Breastfeeding and AIDS in the developing worldLouise Kuhn
Gertrude H Sergievsky Center, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
Curr Opin Pediatr 21:83-93. 2009..Data from recently completed studies provide insight into the safety and hazards of different feeding approaches as well as the use of antiretroviral therapy to prevent postnatal transmission...
- Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIsQuanxin Meng
Wadsworth Center, New York State Department of Health, Albany, New York, USA
Environ Mol Mutagen 48:307-21. 2007..While these data support the continued use of AZT-based therapies during pregnancy, infants receiving prepartum AZT should be monitored long-term for adverse health effects...
- Toxicities associated with dual nucleoside reverse-transcriptase inhibitor regimens in HIV-infected childrenRussell B Van Dyke
Department of Pediatrics, Tulane University Health Sciences Center, 1430 Tulane Avenue, New Orleans, LA 70112, USA
J Infect Dis 198:1599-608. 2008..Human immunodeficiency virus (HIV) therapy includes a backbone of nucleoside reverse-transcriptase inhibitors (NRTIs). Toxicities associated with NRTIs are not fully defined in children...
- CD4/CD8 T-cell ratio predicts HIV infection in infants: the National Heart, Lung, and Blood Institute P2C2 StudyWilliam T Shearer
Department of Pediatrics, Section of Allergy and Immunology, Baylor College of Medicine, Houston, TX, USA
J Allergy Clin Immunol 120:1449-56. 2007..In resource-poor regions of the world, HIV virologic testing is not available...
- Longitudinal changes in regional fat content in HIV-infected children and adolescentsStephen M Arpadi
St Luke s Roosevelt Hospital Center, Columbia University, New York, New York, USA
AIDS 23:1501-9. 2009..The study aim was to compare changes in regional fat distribution in HIV-infected (HIV+) and healthy (HIV-) children and adolescents living in the United States...
- Virologic and immunologic correlates with the magnitude of antibody responses to the hepatitis A vaccine in HIV-infected children on highly active antiretroviral treatmentAdriana Weinberg
Department of Pediatrics, University of Colorado Denver, Aurora, CO 80045, USA
J Acquir Immune Defic Syndr 52:17-24. 2009..We sought to identify the immunologic and virologic factors associated with a robust response to hepatitis A virus (HAV) vaccine in children on highly active antiretroviral treatment...
- Incidence of noninfectious conditions in perinatally HIV-infected children and adolescents in the HAART eraSharon A Nachman
Department of Pediatrics, Stony Brook University Medical Center, Stony Brook, NY 11794 8111, USA
Arch Pediatr Adolesc Med 163:164-71. 2009....
- Maternal viral load and rate of disease progression among vertically HIV-1-infected children: an international meta-analysisJohn P A Ioannidis
Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
AIDS 18:99-108. 2004....
- Combination antiretroviral therapy in african nursing mothers and drug exposure in their infants: new pharmacokinetic and virologic findingsMarc Bulterys
J Infect Dis 192:709-12. 2005
- Ritonavir-based highly active antiretroviral therapy in human immunodeficiency virus type 1-infected infants younger than 24 months of ageEllen Gould Chadwick
Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Pediatr Infect Dis J 24:793-800. 2005..Few data are available regarding clinical outcomes or dosing requirements for the protease inhibitor ritonavir in human immunodeficiency virus (HIV)-infected children younger than under 24 months of age...
- Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to CombivirRao L Divi
CDI Section, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
AIDS 18:1013-21. 2004..In this pilot study we examined mitochondrial integrity in HIV-1-uninfected infants born to HIV-1-infected women receiving Combivir during pregnancy...
- The association between caregiver knowledge of antiretroviral therapy regimens and disease parameters among perinatally human immunodeficiency virus-infected childrenOuzama Nicholson
Partners AIDS Research Center, Charlestown Navy Yard, 149 13th St, Fifth Floor, Charlestown, MA 02129, USA
Arch Pediatr Adolesc Med 160:1307-8. 2006
- Care and treatment of HIV-infected children in Africa: issues and challenges at the district hospital levelAnniek J De Baets
Child Health and Nutrition Unit, Department of Public Health, Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
Pediatr Infect Dis J 26:163-73. 2007..Surmounting the sense of hopelessness by providing district healthcare workers with training in basic pediatric HIV/AIDS care is an urgent priority...
- Mother-to-child transmission of HIV-1: timing and implications for preventionAthena P Kourtis
Division of Reproductive Health, Centers for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
Lancet Infect Dis 6:726-32. 2006..We discuss the implications of this hypothesis and how it could lead to new interventions for the prevention of mother-to-child HIV transmission...
- Antiretroviral treatment and prevention of peripartum and postnatal HIV transmission in West Africa: evaluation of a two-tiered approachBesigin Tonwe-Gold
MTCT Plus Programme, ACONDA, Abidjan, Cote d Ivoire
PLoS Med 4:e257. 2007....
- Immunogenicity, safety, and predictors of response after a pneumococcal conjugate and pneumococcal polysaccharide vaccine series in human immunodeficiency virus-infected children receiving highly active antiretroviral therapyMark J Abzug
University of Colorado School of Medicine, Pediatric Infectious Disease, The Children s Hospital, Denver, CO 80218, USA
Pediatr Infect Dis J 25:920-9. 2006....
- Clinical outcomes and CD4 cell response in children receiving antiretroviral therapy at primary health care facilities in ZambiaCarolyn Bolton-Moore
Centre for Infectious Disease Research in Zambia, Lusaka
JAMA 298:1888-99. 2007....
- Cohort profile: the paediatric antiretroviral treatment programmes in lower-income countries (KIDS-ART-LINC) collaborationElise Arrive
Unité INSERM 593, Institut de Santé Publique, Epidémiologie et Développement ISPED, Universite Victor Segalen, Bordeaux, France
Int J Epidemiol 37:474-80. 2008
- Challenges to re-enrolling perinatally HIV-infected and HIV-exposed but uninfected children into a prospective cohort study: strategies for locating and recruiting hard-to-reach familiesDarcy Freedman
U S Centers for Disease Control and Prevention, National Center for HIV STD TB Prevention, Atlanta, GA, USA
Paediatr Perinat Epidemiol 20:338-47. 2006..The PACTS-HOPE cohort will provide opportunities for future research aimed at understanding the unique effects of HIV on the well-being of HIV-infected children...
- Maternal 12-month response to antiretroviral therapy following prevention of mother-to-child transmission of HIV type 1, Ivory Coast, 2003-2006Patrick A Coffie
Unité Institut National de Santé et de Rechereche Médicale 593, Bordeaux, France
Clin Infect Dis 46:611-21. 2008....
- Association of site-specific and participant-specific factors with retention of children in a long-term pediatric HIV cohort studyPaige L Williams
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA 02115 6017, USA
Am J Epidemiol 167:1375-86. 2008..Although participant characteristics are difficult to modify, the authors identified several potentially modifiable site practices that could be targeted to improve retention...
- Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'IvoireDidier K Ekouevi
ANRS 1201 1202 DITRAME PLUS Project, PACCI Collaboration, Abidjan, Cote d Ivoire, France
AIDS 22:1815-20. 2008..Pregnancy outcomes in women receiving highly active antiretroviral treatment (HAART) in Africa are not well described...
- Boarder babies with AIDS in harlem: lessons in applied public healthStephen W Nicholas
Am J Public Health 92:163-5. 2002
- Ultrasensitive p24 antigen assay for diagnosis of perinatal human immunodeficiency virus type 1 infectionSusan A Fiscus
University of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA
J Clin Microbiol 45:2274-7. 2007..Overall sensitivity and specificity were 91.7% and 98.5%, respectively. After exclusion of infants of less than 7 days of age, the sensitivity and specificity were 93.7% and 98.3%, respectively...
- Disease progression and evolution of the HIV-1 env gene in 24 infected infantsAntonio Carvajal-Rodriguez
Department of Biology, Brigham Young University, 84602 Provo, UT, USA
Infect Genet Evol 8:110-20. 2008..Overall, the results obtained confirm that viral adaptation in the C2V3C3 region of the env gene is related to disease progression, although the statistical characterization of such pattern seems rather difficult...
- Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TCPatricia A Escobar
Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Environ Mol Mutagen 48:330-43. 2007..Overall, the mutagenic effects found in mother-child pairs receiving AZT-based treatments justify their surveillance for long-term genotoxic consequences...
- A simplified weight-based method for pediatric drug dosing for zidovudine and didanosine in resource-limited settingsPaul J Weidle
Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Pediatr Infect Dis J 25:59-64. 2006..Although weight and height can both be measured, it may be impractical to expect providers in resource-limited settings to estimate accurately body surface area...