D L Wheeler

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi request reprint Differential healing response of bone adjacent to porous implants coated with hydroxyapatite and 45S5 bioactive glass
    D L Wheeler
    Colorado State University, Department of Mechanical Engineering, Biomedical Engineering Program, A101 Engineering Building, Ft Collins, Colorado 80523, USA
    J Biomed Mater Res 55:603-12. 2001
  2. ncbi request reprint Grafting of massive tibial subchondral bone defects in a caprine model using beta-tricalcium phosphate versus autograft
    Donna L Wheeler
    Department of Orthopaedics and Rehabilitation, College of Medicine, University of Florida, Gainesville, FL, USA
    J Orthop Trauma 19:85-91. 2005
  3. ncbi request reprint Radiomorphometry and biomechanical assessment of recombinant human bone morphogenetic protein 2 and polymer in rabbit radius ostectomy model
    D L Wheeler
    University of Florida, Department of Orthopaedics, Gainesville 32610, USA
    J Biomed Mater Res 43:365-73. 1998
  4. ncbi request reprint Assessment of resorbable bioactive material for grafting of critical-size cancellous defects
    D L Wheeler
    Department of Orthopaedics, University of Florida, Gainesville 32610, USA
    J Orthop Res 18:140-8. 2000
  5. ncbi request reprint Dietary-induced metabolic acidosis decreases bone mineral density in mature ovariectomized ewes
    J M MacLeay
    Department of Clinical Science, Colorado State University, Fort Collins, CO 80523, USA
    Calcif Tissue Int 75:431-7. 2004
  6. ncbi request reprint Efficacy of silicated calcium phosphate graft in posterolateral lumbar fusion in sheep
    Donna L Wheeler
    Department of Mechanical Engineering, College of Engineering, Orthopaedic Bioengineering Research Laboratory, Colorado State University, A101 Engineering Building, Fort Collins, CO 80523 1374, USA
    Spine J 7:308-17. 2007
  7. ncbi request reprint Hollow calcium phosphate microcarriers for bone regeneration: in vitro osteoproduction and ex vivo mechanical assessment
    Brandon G Santoni
    Department of Mechanical Engineering, Orthopaedic Bioengineering Research Laboratory, Colorado State University, Fort Collins, CO 80523, USA
    Biomed Mater Eng 17:277-89. 2007
  8. ncbi request reprint A mechanical and computational investigation on the effects of conduit orientation on the strength of massive bone allografts
    Brandon G Santoni
    Department of Clinical Sciences, Animal Cancer Center, Colorado State University, Fort Collins, CO 80523, USA
    Bone 41:769-74. 2007
  9. ncbi request reprint Biomechanical evaluation of retrieved massive allografts: preliminary results
    D L Wheeler
    Department of Mechanical Engineering, Biomedical Engineering Program, Colorado State University, Fort Collins, CO 80523, USA
    Biomed Sci Instrum 37:251-6. 2001
  10. ncbi request reprint Cortical bone graft and endoprosthesis in the distal radius of dogs: a biomechanical comparison of two different limb-sparing techniques
    Julius M Liptak
    Animal Cancer Center and Department of Mechanical and Biomedical Engineering, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA
    Vet Surg 35:150-60. 2006

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Differential healing response of bone adjacent to porous implants coated with hydroxyapatite and 45S5 bioactive glass
    D L Wheeler
    Colorado State University, Department of Mechanical Engineering, Biomedical Engineering Program, A101 Engineering Building, Ft Collins, Colorado 80523, USA
    J Biomed Mater Res 55:603-12. 2001
    ..In summary, 45S5-coated implants exhibited greater bone ingrowth compared to HA-coated and CTL implants, and they maintained their mechanical integrity over time...
  2. ncbi request reprint Grafting of massive tibial subchondral bone defects in a caprine model using beta-tricalcium phosphate versus autograft
    Donna L Wheeler
    Department of Orthopaedics and Rehabilitation, College of Medicine, University of Florida, Gainesville, FL, USA
    J Orthop Trauma 19:85-91. 2005
    ..05). These results indicated that beta-tricalcium phosphate particles might be a useful graft material for local repair of load bearing skeletal sites such as depressed tibial plateau fractures...
  3. ncbi request reprint Radiomorphometry and biomechanical assessment of recombinant human bone morphogenetic protein 2 and polymer in rabbit radius ostectomy model
    D L Wheeler
    University of Florida, Department of Orthopaedics, Gainesville 32610, USA
    J Biomed Mater Res 43:365-73. 1998
    ..These radiomorphometric and biomechanical results indicate PLA may be a suitable carrier for rhBMP-2 used for skeletal regeneration...
  4. ncbi request reprint Assessment of resorbable bioactive material for grafting of critical-size cancellous defects
    D L Wheeler
    Department of Orthopaedics, University of Florida, Gainesville 32610, USA
    J Orthop Res 18:140-8. 2000
    ..The 58S and 77S materials resorbed faster than the 45S5 materials. Mechanically, the compressive characteristics of all grafted defects were equivalent or greater than those of normal bone at all time points...
  5. ncbi request reprint Dietary-induced metabolic acidosis decreases bone mineral density in mature ovariectomized ewes
    J M MacLeay
    Department of Clinical Science, Colorado State University, Fort Collins, CO 80523, USA
    Calcif Tissue Int 75:431-7. 2004
    ..Therefore, the goal of this pilot study was to determine if bone mineral density (BMD) loss could be induced using DIMA in skeletally mature ovariectomized (OVX) ewes...
  6. ncbi request reprint Efficacy of silicated calcium phosphate graft in posterolateral lumbar fusion in sheep
    Donna L Wheeler
    Department of Mechanical Engineering, College of Engineering, Orthopaedic Bioengineering Research Laboratory, Colorado State University, A101 Engineering Building, Fort Collins, CO 80523 1374, USA
    Spine J 7:308-17. 2007
    ..Silicate substitution has been shown to enhance the bioactivity of calcium phosphates and may obviate the need for autologous supplementation...
  7. ncbi request reprint Hollow calcium phosphate microcarriers for bone regeneration: in vitro osteoproduction and ex vivo mechanical assessment
    Brandon G Santoni
    Department of Mechanical Engineering, Orthopaedic Bioengineering Research Laboratory, Colorado State University, Fort Collins, CO 80523, USA
    Biomed Mater Eng 17:277-89. 2007
    ..These preliminary in vitro and ex vivo results indicate the clinical potential of the hollow calcium phosphate carriers as successful load-bearing delivery vehicles for OP-1...
  8. ncbi request reprint A mechanical and computational investigation on the effects of conduit orientation on the strength of massive bone allografts
    Brandon G Santoni
    Department of Clinical Sciences, Animal Cancer Center, Colorado State University, Fort Collins, CO 80523, USA
    Bone 41:769-74. 2007
    ....
  9. ncbi request reprint Biomechanical evaluation of retrieved massive allografts: preliminary results
    D L Wheeler
    Department of Mechanical Engineering, Biomedical Engineering Program, Colorado State University, Fort Collins, CO 80523, USA
    Biomed Sci Instrum 37:251-6. 2001
    ..Testing and analysis of more specimens continue in order to corroborate these initial results...
  10. ncbi request reprint Cortical bone graft and endoprosthesis in the distal radius of dogs: a biomechanical comparison of two different limb-sparing techniques
    Julius M Liptak
    Animal Cancer Center and Department of Mechanical and Biomedical Engineering, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA
    Vet Surg 35:150-60. 2006
    ..To compare the biomechanical properties of cortical bone and surgical steel endoprosthesis for limb-sparing surgery of the distal radius in dogs and evaluate the role of the ulna in providing stability to the reconstructed limb...
  11. ncbi request reprint Quantification methodology for peripheral quantitative computed tomography (PQCT) data using public domain software
    M E Kovach
    Orthopedic Bioengineering Research Laboratory, Colorado State University, Fort Collins, CO 80526, USA
    Biomed Sci Instrum 40:161-7. 2004
    ..To develop a method for viewing, processing and acquiring 3-dimensional volumetric data from existing ovine spinal peripheral quantitative computed tomography (PQCT) scans of posterior lateral fusion...
  12. ncbi request reprint Assessment of subchondral bone mineral density in equine metacarpophalangeal and stifle joints
    J E Walker
    Orthopaedic Bioengineering Research Laboratory, Department of Mechanical Engineering, Colorado State University, USA
    Biomed Sci Instrum 40:272-6. 2004
    ..Mechanical properties of the overlying cartilage are currently being analyzed to correlate with these results and provide a possible diagnostic method to investigate OA progression...
  13. ncbi request reprint Evaluation of subchondral bone mineral density associated with articular cartilage structure and integrity in healthy equine joints with different functional demands
    Chad W Lewis
    Department of Mechanical Engineering, College of Engineering, Colorado State University, Fort Collins, CO 80523, USA
    Am J Vet Res 66:1823-9. 2005
    ..To determine and correlate subchondral bone mineral density and overlying cartilage structure and tensile integrity in mature healthy equine stifle (low magnitude loading) and metacarpophalangeal (high magnitude loading) joints...
  14. ncbi request reprint Ex vivo comparison of one versus two distal screws in 8 mm model 11 interlocking nails used to stabilize canine distal femoral fractures
    Michael R Reems
    Department of Clinical Sciences, Colorado State University, Fort Collins, CO, USA
    Vet Surg 35:161-7. 2006
    ..To compare the structural properties of an 8 mm model 11 interlocking nail (IN) with 2 proximal and 2 distal screws (2/2) to 2 proximal and 1 distal screws (2/1) in an unstable canine fracture model...
  15. ncbi request reprint In vivo BMP-7 (OP-1) enhancement of osteoporotic vertebral bodies in an ovine model
    Frank M Phillips
    Rush University Medical Center, 1725 W Harrison Street, Suite 1063, Chicago, IL 60612, USA
    Spine J 6:500-6. 2006
    ..The mechanism of action of the bone morphogenetic protein (BMP) family theoretically makes these molecules candidates for rapidly enhancing local bone structure...
  16. ncbi request reprint Use of a resorbable sheet in iliac crest reconstruction in a sheep model
    G Bryan Cornwall
    MacroPore Biosurgery, Inc, San Diego, Calif, USA
    Orthopedics 25:s1167-71. 2002
    ..Based upon the results of the present study, MacroPore resorbable protective sheeting can improve bone regeneration significantly within the donor site following tricortical iliac crest graft harvesting...
  17. ncbi request reprint Efficacy of osteogenic protein-1 in a challenging multilevel fusion model
    Matthew J Mermer
    Department of Orthopaedic Surgery, University of California, Davis, Sacramento 95817, USA
    Spine (Phila Pa 1976) 29:249-56. 2004
    ..A therapeutic study compared the influence of osteogenic protein-1 to autograft and collagen carrier in multilevel sheep spine fusions...
  18. ncbi request reprint Use of a resorbable sheet in iliac crest reconstruction in a sheep model
    G Bryan Cornwall
    MacroPore Biosurgery, Inc, San Diego, California, USA
    J Neurosurg 97:456-9. 2002
    ..The objective of this study was to evaluate the postoperative regeneration of iliac crest donor defects in an animal model after harvesting a full-thickness tricortical graft...
  19. pmc Gene therapy to enhance allograft incorporation after host tissue irradiation
    Brandon G Santoni
    Department of Clinical Sciences, Colorado State University Veterinary Medical Center, Fort Collins, CO 80523, USA
    Clin Orthop Relat Res 466:1921-9. 2008
    ..Although gene therapy may hold promise as a novel technique to improve allograft incorporation, our data do not support that contention with the current approach...
  20. ncbi request reprint Radiographic and histologic analysis of the tibial tunnel after allograft anterior cruciate ligament reconstruction in goats
    N Lindsay Harris
    Department of Orthopedics, Sports Medicine Clinic, University of Colorado Health Sciences Center, Denver, CO, USA
    Am J Sports Med 30:368-73. 2002
    ....