Terry R Spraker

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. pmc Transmissibility of caprine scrapie in ovine transgenic mice
    Katherine I O'Rourke
    United States Department of Agriculture, Agricultural Research Service, Pullman, WA 99164, USA
    BMC Vet Res 8:42. 2012
  2. pmc Association analysis of PRNP gene region with chronic wasting disease in Rocky Mountain elk
    Stephen N White
    Animal Disease Research Unit, Agricultural Research Service, U, S, Department of Agriculture, Pullman, WA 99164, USA
    BMC Res Notes 3:314. 2010
  3. ncbi request reprint Causes of mortality in northern fur seals (Callorhinus ursinus), St. Paul Island, Pribilof Islands, Alaska, 1986-2006
    Terry R Spraker
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80526, USA
    J Wildl Dis 46:450-73. 2010
  4. doi request reprint Detection of the abnormal isoform of the prion protein associated with chronic wasting disease in the optic pathways of the brain and retina of Rocky Mountain elk (Cervus elaphus nelsoni)
    T R Spraker
    Colorado State University Diagnostic Laboratory, 300 West Drake Road, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80526, USA
    Vet Pathol 47:536-46. 2010
  5. ncbi request reprint Hookworm enteritis with bacteremia in California sea lion pups on San Miguel Island
    Terry R Spraker
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80526, USA
    J Wildl Dis 43:179-88. 2007
  6. ncbi request reprint Detection of PrP(CWD) in postmortem rectal lymphoid tissues in Rocky Mountain elk (Cervus elaphus nelsoni) infected with chronic wasting disease
    Terry R Spraker
    College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80526, USA
    J Vet Diagn Invest 18:553-7. 2006
  7. ncbi request reprint Impact of age and sex of Rocky Mountain elk (Cervus elaphus nelsoni) on follicle counts from rectal mucosal biopsies for preclinical detection of chronic wasting disease
    Terry R Spraker
    USDA APHIS Wildlife Services National Wildlife Research Center, Fort Collins, CO 80521, USA
    J Vet Diagn Invest 21:868-70. 2009
  8. ncbi request reprint PrPCWD in rectal lymphoid tissue of deer (Odocoileus spp.)
    Lisa L Wolfe
    Colorado Division of Wildlife, Wildlife Research Center, 317 West Prospect Road, Fort Collins, CO 80526 2097, USA
    J Gen Virol 88:2078-82. 2007
  9. doi request reprint Immunization with a synthetic peptide vaccine fails to protect mule deer (Odocoileus hemionus) from chronic wasting disease
    John L Pilon
    United States Department of Agriculture USDA, Animal and Plant Health Inspection Service APHIS, Wildlife Services WS, National Wildlife Research Center NWRC, Fort Collins, Colorado 80521, USA
    J Wildl Dis 49:694-8. 2013
  10. doi request reprint Efficacy of antemortem rectal biopsies to diagnose and estimate prevalence of chronic wasting disease in free-ranging cow elk (Cervus elaphus nelsoni)
    Ryan J Monello
    National Park Service, Biological Resource Management Division, Fort Collins, CO 80525, USA
    J Wildl Dis 49:270-8. 2013

Collaborators

Detail Information

Publications35

  1. pmc Transmissibility of caprine scrapie in ovine transgenic mice
    Katherine I O'Rourke
    United States Department of Agriculture, Agricultural Research Service, Pullman, WA 99164, USA
    BMC Vet Res 8:42. 2012
    ....
  2. pmc Association analysis of PRNP gene region with chronic wasting disease in Rocky Mountain elk
    Stephen N White
    Animal Disease Research Unit, Agricultural Research Service, U, S, Department of Agriculture, Pullman, WA 99164, USA
    BMC Res Notes 3:314. 2010
    ..Thus, additional genetic variants might provide increased protection, either alone or in combination with 132L...
  3. ncbi request reprint Causes of mortality in northern fur seals (Callorhinus ursinus), St. Paul Island, Pribilof Islands, Alaska, 1986-2006
    Terry R Spraker
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80526, USA
    J Wildl Dis 46:450-73. 2010
    ..We found no evidence to implicate infectious diseases as a cause in the recent decline of northern fur seals...
  4. doi request reprint Detection of the abnormal isoform of the prion protein associated with chronic wasting disease in the optic pathways of the brain and retina of Rocky Mountain elk (Cervus elaphus nelsoni)
    T R Spraker
    Colorado State University Diagnostic Laboratory, 300 West Drake Road, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80526, USA
    Vet Pathol 47:536-46. 2010
    ..This study demonstrates PrP(CWD) accumulation in nuclei of the visual pathways of the brain, followed by PrP(CWD) in the retina...
  5. ncbi request reprint Hookworm enteritis with bacteremia in California sea lion pups on San Miguel Island
    Terry R Spraker
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80526, USA
    J Wildl Dis 43:179-88. 2007
    ..The primary lesions in 133 (72%) of the pups were an enteritis associated with hookworms and infections in major organs. Emaciation/starvation in 43 pups (26%) was the second most important cause of death...
  6. ncbi request reprint Detection of PrP(CWD) in postmortem rectal lymphoid tissues in Rocky Mountain elk (Cervus elaphus nelsoni) infected with chronic wasting disease
    Terry R Spraker
    College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80526, USA
    J Vet Diagn Invest 18:553-7. 2006
    ..The use of rectal mucosal lymphoid tissues may be suitable for a live-animal diagnostic test as part of an integrated management strategy to limit CWD in elk...
  7. ncbi request reprint Impact of age and sex of Rocky Mountain elk (Cervus elaphus nelsoni) on follicle counts from rectal mucosal biopsies for preclinical detection of chronic wasting disease
    Terry R Spraker
    USDA APHIS Wildlife Services National Wildlife Research Center, Fort Collins, CO 80521, USA
    J Vet Diagn Invest 21:868-70. 2009
    ..Rectal biopsies were an accurate test to diagnose preclinical stages of CWD in elk but may be best suited to elk that are less then 8.5 years of age...
  8. ncbi request reprint PrPCWD in rectal lymphoid tissue of deer (Odocoileus spp.)
    Lisa L Wolfe
    Colorado Division of Wildlife, Wildlife Research Center, 317 West Prospect Road, Fort Collins, CO 80526 2097, USA
    J Gen Virol 88:2078-82. 2007
    ..i. and none of three 96SS individuals had PrP(CWD) in their rectal mucosa by 751 days p.i. These findings support further evaluation of rectal mucosa sampling in CWD surveillance...
  9. doi request reprint Immunization with a synthetic peptide vaccine fails to protect mule deer (Odocoileus hemionus) from chronic wasting disease
    John L Pilon
    United States Department of Agriculture USDA, Animal and Plant Health Inspection Service APHIS, Wildlife Services WS, National Wildlife Research Center NWRC, Fort Collins, Colorado 80521, USA
    J Wildl Dis 49:694-8. 2013
    ..All vaccinates responded to both peptide conjugates present in the combination vaccine as measured by enzyme-linked immunosorbent assay. However, all deer eventually became infected regardless of vaccine status...
  10. doi request reprint Efficacy of antemortem rectal biopsies to diagnose and estimate prevalence of chronic wasting disease in free-ranging cow elk (Cervus elaphus nelsoni)
    Ryan J Monello
    National Park Service, Biological Resource Management Division, Fort Collins, CO 80525, USA
    J Wildl Dis 49:270-8. 2013
    ..Prevalence estimates from this population are the highest reported to date in elk and indicate that under appropriate conditions, CWD may be able to affect the dynamics of high-density elk populations...
  11. pmc Intranasal inoculation of white-tailed deer (Odocoileus virginianus) with lyophilized chronic wasting disease prion particulate complexed to montmorillonite clay
    Tracy A Nichols
    National Wildlife Research Center, US Department of Agriculture, Animal and Plant Health Inspection Service, Wildlife Services, Fort Collins, Colorado, USA
    PLoS ONE 8:e62455. 2013
    ..Our results demonstrate that CWD can be efficiently transmitted utilizing Mte particles as a prion carrier and intranasal exposure...
  12. ncbi request reprint Antemortem detection of PrPCWD in preclinical, ranch-raised Rocky Mountain elk (Cervus elaphus nelsoni) by biopsy of the rectal mucosa
    Terry R Spraker
    Colorado State University Diagnostic Laboratory, College of Veterinary Medecine, Colorado State University, Fort Collins, CO, USA
    J Vet Diagn Invest 21:15-24. 2009
    ..These findings support the analysis of antemortem biopsy of the rectal mucosa samples as part of an integrated strategy to manage chronic wasting disease in Rocky Mountain elk...
  13. ncbi request reprint A natural case of chronic wasting disease in a free-ranging moose (Alces alces shirasi)
    Laurie A Baeten
    Colorado Division of Wildlife, Wildlife Research Center, Fort Collins, CO 80526 2097, USA
    J Wildl Dis 43:309-14. 2007
    ..In October 2006, two additional free-ranging moose were diagnosed with CWD. Epidemiology and implications of CWD in moose remain to be determined...
  14. doi request reprint Detection of prion protein in the cerebrospinal fluid of elk (Cervus canadensis nelsoni) with chronic wasting disease using protein misfolding cyclic amplification
    Tracy A Nichols
    National Wildlife Research Center, U S Department of Agriculture, Animal and Plant Health Inspection Service, 4101 La Porte Avenue, Fort Collins, CO 80521, USA
    J Vet Diagn Invest 24:746-9. 2012
    ..The data suggests that CWD prions can be detected in the CSF of elk, but only relatively late in the course of the disease...
  15. ncbi request reprint Detection of PrPCWD in feces from naturally exposed Rocky Mountain elk (Cervus elaphus nelsoni) using protein misfolding cyclic amplification
    Bruce Pulford
    Department of Microbiology, Immunology and Pathology, Prion Research Program, Colorado State University, 1619 Campus Delivery, Fort Collins, Colorado 80523, USA
    J Wildl Dis 48:425-34. 2012
    ..These data show for the first time PrP(CWD) in feces from naturally exposed free-ranging elk and demonstrate the potential of PMCA as a new, noninvasive CWD diagnostic tool to complement IHC...
  16. ncbi request reprint Field validation and assessment of an enzyme-linked immunosorbent assay for detecting chronic wasting disease in mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus), and Rocky Mountain elk (Cervus elaphus nelsoni)
    Charles P Hibler
    Veterinary Diagnostic Laboratory, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Diagn Invest 15:311-9. 2003
    ..Based on these data, brELISA was determined to be an excellent rapid test for screening large numbers of samples in surveys designed to detect CWD infections in deer and elk populations...
  17. ncbi request reprint Failure of fallow deer (Dama dama) to develop chronic wasting disease when exposed to a contaminated environment and infected mule deer (Odocoileus hemionus)
    Jack C Rhyan
    National Wildlife Research Center, US Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, Fort Collins, Colorado 80521, USA
    J Wildl Dis 47:739-44. 2011
    ....
  18. ncbi request reprint Oral papillomatosis in Canada lynx (Lynx canadensis)
    Lisa L Wolfe
    Colorado Division of Wildlife, Wildlife Research Center, 317 W Prospect Rd, Fort Collins, Colorado 80526 2097, USA
    J Wildl Dis 43:731-3. 2007
    ....
  19. ncbi request reprint A bighorn sheep die-off in southern Colorado involving a Pasteurellaceae strain that may have originated from syntopic cattle
    Lisa L Wolfe
    Colorado Division of Wildlife, Wildlife Research Center, 317 West Prospect Road, Fort Collins, Colorado 80526 2097, USA
    J Wildl Dis 46:1262-8. 2010
    ..Our and others' findings suggest that intimate interactions between wild sheep and cattle should be discouraged as part of a comprehensive approach to health management and conservation of North American wild sheep species...
  20. doi request reprint In vitro strain adaptation of CWD prions by serial protein misfolding cyclic amplification
    Crystal Meyerett
    Department of Microbiology, Immunology, and Pathology, Colorado State University, College of Veterinary Medicine and Biomedical Sciences, Fort Collins, CO 80523, USA
    Virology 382:267-76. 2008
    ..Thus sPMCA may represent a powerful tool to assess prion strain adaptation and species barriers in vitro...
  21. ncbi request reprint Infectious prions in the saliva and blood of deer with chronic wasting disease
    Candace K Mathiason
    Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biological Sciences CVMBS, Colorado State University CSU, Fort Collins, CO 80523, USA
    Science 314:133-6. 2006
    ..The results help to explain the facile transmission of CWD among cervids and prompt caution concerning contact with body fluids in prion infections...
  22. ncbi request reprint Malignant catarrhal fever associated with ovine herpesvirus-2 in free-ranging mule deer in Colorado
    Patricia C Schultheiss
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Wildl Dis 43:533-7. 2007
    ..These cases indicate that fatal OHV-2 associated MCF can occur in free-ranging mule deer exposed to domestic sheep that overlap their range...
  23. ncbi request reprint Preclinical diagnosis of chronic wasting disease in captive mule deer (Odocoileus hemionus) and white-tailed deer (Odocoileus virginianus) using tonsillar biopsy
    Margaret A Wild
    Colorado Division of Wildlife, Wildlife Research Center, 317 W Prospect Road, Fort Collins, CO 80526, USA
    J Gen Virol 83:2629-34. 2002
    ..Tonsillar biopsy evaluated with IHC staining is a useful technique for the preclinical diagnosis of CWD in live mule deer and white-tailed deer when intensive management approaches are possible...
  24. pmc Experimental infection of raccoons (Procyon lotor) with West Nile virus
    J Jeffrey Root
    United States Department of Agriculture, Wildlife Services, National Wildlife Research Center, Fort Collins, Colorado 80521, USA
    Am J Trop Med Hyg 83:803-7. 2010
    ..Considering their behavioral ecology, including repeated use of same-site latrines, high levels of fecal shedding could potentially lead to interspecies fecal-oral WNV transmission...
  25. ncbi request reprint Plague as a mortality factor in Canada lynx (Lynx canadensis) reintroduced to Colorado
    Margaret A Wild
    Colorado Division of Wildlife, Wildlife Research Section, 317 W Prospect Rd, Fort Collins, Colorado 80526, USA
    J Wildl Dis 42:646-50. 2006
    ..Lymphadenomegaly was observed in only one plague-affected lynx. We hypothesize that these Canada lynx were exposed to Y. pestis by infected prey, and these are the first reports of plague in this species...
  26. ncbi request reprint Contrasting effects of heterozygosity on survival and hookworm resistance in California sea lion pups
    Karina Acevedo-Whitehouse
    Laboratory of Molecular Ecology, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Mol Ecol 15:1973-82. 2006
    ..Our study could have important implications for the conservation of small, isolated or threatened populations, particularly when they are at a risk of facing pathogenic challenges...
  27. ncbi request reprint Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibility to chronic wasting disease in white-tailed deer
    Katherine I O'Rourke
    US Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, 3003 ADBF, Pullman, WA 99164, USA
    J Gen Virol 85:1339-46. 2004
    ....
  28. pmc A species barrier limits transmission of chronic wasting disease to mink (Mustela vison)
    Robert D Harrington
    Department of Comparative Medicine, University of Washington, Seattle, WA 98195 7190, USA
    J Gen Virol 89:1086-96. 2008
    ..The demonstration of a species barrier in cervid-to-mustelid prion transmission indicates that mink are unlikely to be involved in natural CWD transmission...
  29. ncbi request reprint Preliminary observations of genetic susceptibility of elk (Cervus elaphus nelsoni) to chronic wasting disease by experimental oral inoculation
    Amir N Hamir
    National Animal Disease Center, ARS, USDA, Ames, IA 50010, USA
    J Vet Diagn Invest 18:110-4. 2006
    ..All 4 LL elk are alive at PI year 4 and are clinically normal, which suggests that 132LL elk may have reduced susceptibility to oral infection with CWD-infected material or may have prolonged incubation time...
  30. ncbi request reprint Infectious disease and the decline of Steller sea lions (Eumetopias jubatus) in Alaska, USA: insights from serologic data
    Kathy A Burek
    Alaska Veterinary Pathology Services, P O Box 773072, Eagle River, AK 99577, USA
    J Wildl Dis 41:512-24. 2005
    ..Systematic monitoring for disease agents and their effects is needed to determine whether infectious disease currently plays a role in the decline and lack of recovery of Steller sea lions...
  31. ncbi request reprint Chronic wasting disease in a Wisconsin white-tailed deer farm
    Delwyn P Keane
    University of Wisconsin, Wisconsin Veterinary Diagnostic Laboratory, Madison, WI 53706, USA
    J Vet Diagn Invest 20:698-703. 2008
    ..Antemortem testing by biopsy of recto-anal mucosal-associated lymphoid tissue (or other peripheral lymphoid tissue) may be a useful adjunct to tonsil biopsy for surveillance in captive herds at risk for CWD infection...
  32. ncbi request reprint Geographic variation in marine turtle fibropapillomatosis
    Rebecca J Greenblatt
    Cornell University College of Veterinary Medicine Department of Microbiology and Immunology, Ithaca, New York 14853, USA
    J Zoo Wildl Med 36:527-30. 2005
    ..These cases illustrate geographic variation in both the pathology and the virology of fibropapillomatosis...
  33. ncbi request reprint Elk with a long incubation prion disease phenotype have a unique PrPd profile
    Katherine I O'Rourke
    United States Department of Agriculture, Agricultural Research Service, Animal Disease Research Unit, Pullman, Washington 99164, USA
    Neuroreport 18:1935-8. 2007
    ..We now report that elk lacking the predisposing 132-methionine allele develop chronic wasting disease after a long incubation period and display a novel PrP folding pattern...
  34. ncbi request reprint Distribution of tissue enzymes in three species of pinnipeds
    Deborah A Fauquier
    The Marine Mammal Center, 1065 Fort Cronkhite, Marin Headlands, Sausalito, California 94965, USA
    J Zoo Wildl Med 39:1-5. 2008
    ..These results suggest that concurrent analysis of SDH, ALT, and CK would provide high specificity and sensitivity for the detection of hepatic lesions, and allow differentiation of liver from skeletal muscle lesions in pinniped species...
  35. pmc Pregnancy status and fetal prion genetics determine PrPSc accumulation in placentomes of scrapie-infected sheep
    Wenbin Tuo
    Animal Disease Research Unit, Agricultural Research Service, U S Department of Agriculture, Pullman, WA 99164, USA
    Proc Natl Acad Sci U S A 99:6310-5. 2002
    ..These results indicate that accumulation of PrP(Sc) is eliminated or reduced to undetectable levels in reproductive and placental tissues if infected ewes are not pregnant or conceive conceptuses with a resistant PrP genotype...