Research Topics
Genomes and Genes | Eric D RossSummaryAffiliation: Colorado State University Country: USA Publications
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Detail Information
Publications
The effects of amino acid composition on yeast prion formation and prion domain interactionsEric D Ross
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO, USA
Prion 4:60-5. 2010..This observation, combined with the growing number of yeast prions, suggests that a broad network of interactions between heterologous glutamine/asparagine-rich proteins may affect yeast prion formation...
Compositional determinants of prion formation in yeastJames A Toombs
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
Mol Cell Biol 30:319-32. 2010..Additionally, our results explain why traditional amyloid prediction algorithms fail to accurately predict amyloid formation by the glutamine/asparagine-rich yeast prion domains...
Interactions between non-identical prion proteinsAaron C Gonzalez Nelson
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
Semin Cell Dev Biol 22:437-43. 2011....
A promiscuous prion: efficient induction of [URE3] prion formation by heterologous prion domainsCarley D Ross
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
Genetics 183:929-40. 2009..Remarkably, all but one of these domains were also able to efficiently increase [URE3] formation. These results suggest that a wide variety of proteins could potentially affect [URE3] formation...
[PSI+] maintenance is dependent on the composition, not primary sequence, of the oligopeptide repeat domainJames A Toombs
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
PLoS ONE 6:e21953. 2011..Furthermore, we demonstrate that compositional requirements for the repeat domain are distinct from those of the nucleation domain, indicating that prion nucleation and propagation are driven by distinct compositional features...
Intrinsic protein disorder, amino acid composition, and histone terminal domainsJeffrey C Hansen
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
J Biol Chem 281:1853-6. 2006..We also discuss the potential structural consequences of acetylation and methylation of lysine residues embedded in intrinsically disordered histone tail domains...
De novo design of synthetic prion domainsJames A Toombs
Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
Proc Natl Acad Sci U S A 109:6519-24. 2012....
Fitting yeast and mammalian prion aggregation kinetic data with the Finke-Watzky two-step model of nucleation and autocatalytic growthMurielle A Watzky
Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523, USA
Biochemistry 47:10790-800. 2008..Key limitations of the F-W model are listed to prevent overinterpretation of the data being analyzed, limitations that derive ultimately from the model's simplicity. Finally, possible avenues of future research are suggested...
