Anireddy S N Reddy

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. pmc SpliceGrapher: detecting patterns of alternative splicing from RNA-Seq data in the context of gene models and EST data
    Mark F Rogers
    Department of Computer Science, 1873 Campus Delivery, Colorado State University, Fort Collins, CO 80523 1873, USA
    Genome Biol 13:R4. 2012
  2. pmc Analysis of EF-hand-containing proteins in Arabidopsis
    Irene S Day
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Genome Biol 3:RESEARCH0056. 2002
  3. ncbi request reprint A plant kinesin heavy chain-like protein is a calmodulin-binding protein
    A S Reddy
    Department of Biology, Colorado State University, Fort Collins 80523, USA
    Plant J 10:9-21. 1996
  4. ncbi request reprint Plant serine/arginine-rich proteins and their role in pre-mRNA splicing
    Anireddy S N Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Trends Plant Sci 9:541-7. 2004
  5. ncbi request reprint Characterization of a pathogen-induced calmodulin-binding protein: mapping of four Ca2+-dependent calmodulin-binding domains
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Plant Mol Biol 52:143-59. 2003
  6. ncbi request reprint The calmodulin-binding domain from a plant kinesin functions as a modular domain in conferring Ca2+-calmodulin regulation to animal plus- and minus-end kinesins
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    J Biol Chem 277:48058-65. 2002
  7. ncbi request reprint Genes encoding calmodulin-binding proteins in the Arabidopsis genome
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 277:9840-52. 2002
  8. ncbi request reprint Isolation and characterization of a novel calmodulin-binding protein from potato
    Anireddy S N Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 277:4206-14. 2002
  9. pmc Analysis of the myosins encoded in the recently completed Arabidopsis thaliana genome sequence
    A S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Genome Biol 2:RESEARCH0024. 2001
  10. ncbi request reprint A calmodulin binding protein from Arabidopsis is induced by ethylene and contains a DNA-binding motif
    A S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Biochem Biophys Res Commun 279:762-9. 2000

Collaborators

Detail Information

Publications41

  1. pmc SpliceGrapher: detecting patterns of alternative splicing from RNA-Seq data in the context of gene models and EST data
    Mark F Rogers
    Department of Computer Science, 1873 Campus Delivery, Colorado State University, Fort Collins, CO 80523 1873, USA
    Genome Biol 13:R4. 2012
    ..SpliceGrapher is available for download at http://SpliceGrapher.sf.net...
  2. pmc Analysis of EF-hand-containing proteins in Arabidopsis
    Irene S Day
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Genome Biol 3:RESEARCH0056. 2002
    ..This motif is a conserved helix-loop-helix structure that can bind a single Ca2+ ion. To identify all EF-hand-containing proteins in Arabidopsis, we analyzed its completed genome sequence for genes encoding EF-hand-containing proteins...
  3. ncbi request reprint A plant kinesin heavy chain-like protein is a calmodulin-binding protein
    A S Reddy
    Department of Biology, Colorado State University, Fort Collins 80523, USA
    Plant J 10:9-21. 1996
    ..The presence of a calmodulin-binding motif and a motor domain in a single polypeptide suggests regulation of kinesin heavy chain driven motor function(s) by calcium and calmodulin...
  4. ncbi request reprint Plant serine/arginine-rich proteins and their role in pre-mRNA splicing
    Anireddy S N Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Trends Plant Sci 9:541-7. 2004
    ..A serine/arginine-rich (SR) family of proteins is implicated in constitutive and alternative splicing of pre-mRNAs. Here I review recent progress in elucidating the roles of serine/arginine-rich proteins in pre-mRNA splicing...
  5. ncbi request reprint Characterization of a pathogen-induced calmodulin-binding protein: mapping of four Ca2+-dependent calmodulin-binding domains
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Plant Mol Biol 52:143-59. 2003
    ..Our data suggest a role for PICBP in Ca2+-mediated defense signaling and cell-death. Furthermore, PICBP is the first identified CBP in eukaryotes with four Ca2+-dependent CaM-binding domains...
  6. ncbi request reprint The calmodulin-binding domain from a plant kinesin functions as a modular domain in conferring Ca2+-calmodulin regulation to animal plus- and minus-end kinesins
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    J Biol Chem 277:48058-65. 2002
    ..Our data also support the hypothesis that CaM-binding kinesins may have evolved by addition of a CBD to a kinesin motor domain...
  7. ncbi request reprint Genes encoding calmodulin-binding proteins in the Arabidopsis genome
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 277:9840-52. 2002
    ..Our analyses identified several hypothetical proteins in the Arabidopsis genome as CaM targets, suggesting their involvement in Ca(2+)-mediated signaling networks...
  8. ncbi request reprint Isolation and characterization of a novel calmodulin-binding protein from potato
    Anireddy S N Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 277:4206-14. 2002
    ..Fusion of the N-terminal region of the protein containing six of the seven nuclear localization signals to the reporter gene beta-glucuronidase targeted the reporter gene to the nucleus, suggesting a nuclear role for PCBP...
  9. pmc Analysis of the myosins encoded in the recently completed Arabidopsis thaliana genome sequence
    A S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Genome Biol 2:RESEARCH0024. 2001
    ..The role of myosin in these processes has been established in a few cases but many questions remain to be answered about the number, types and roles of myosins in plants...
  10. ncbi request reprint A calmodulin binding protein from Arabidopsis is induced by ethylene and contains a DNA-binding motif
    A S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Biochem Biophys Res Commun 279:762-9. 2000
    ....
  11. ncbi request reprint Structural organization of a gene encoding a novel calmodulin-binding kinesin-like protein from Arabidopsis
    A S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    Gene 204:195-200. 1997
    ..However, Arabidopsis KCBP together with its homologs from potato and tobacco constitute a distinct group within the C-terminal subfamily of motors which is consistent with structural and functional features of KCBP...
  12. ncbi request reprint Interaction of a kinesin-like protein with calmodulin isoforms from Arabidopsis
    V S Reddy
    Department of Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 274:31727-33. 1999
    ..However, the affinity of calmodulin-4 and -6 isoforms for the motor was about the same. Based on these studies, we conclude that all calmodulin isoforms bind to the motor protein but with different affinities...
  13. pmc KIC, a novel Ca2+ binding protein with one EF-hand motif, interacts with a microtubule motor protein and regulates trichome morphogenesis
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Plant Cell 16:185-200. 2004
    ..These results suggest that KIC modulates the activity of KCBP in response to changes in cytosolic Ca2+ and regulates trichome morphogenesis...
  14. ncbi request reprint Analysis of calcium/calmodulin regulation of a plant kinesin using co-sedimentation and ATPase assays
    Anireddy S N Reddy
    Department of Biology, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO, USA
    Methods Mol Biol 392:23-36. 2007
    ..This chapter describes the methods used in elucidating the regulation of this motor protein by calcium/calmodulin...
  15. ncbi request reprint Alternative splicing of pre-mRNAs of Arabidopsis serine/arginine-rich proteins: regulation by hormones and stresses
    Saiprasad Goud Palusa
    Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
    Plant J 49:1091-107. 2007
    ..Together our results indicate that Arabidopsis SR genes generate surprisingly large transcriptome complexity, which is altered by stresses and hormones...
  16. pmc Regulation of plant developmental processes by a novel splicing factor
    Gul Shad Ali
    Department of Biology and Program in Molecular Plant Biology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 2:e471. 2007
    ..These results indicate that SR45 is a novel plant-specific splicing factor that plays a crucial role in regulating developmental processes...
  17. doi request reprint Extensive coupling of alternative splicing of pre-mRNAs of serine/arginine (SR) genes with nonsense-mediated decay
    Saiprasad G Palusa
    Department of Biology, Program in Molecular Plant Biology, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    New Phytol 185:83-9. 2010
    ..These results show widespread coupling of alternative splicing with NMD in the SR gene family, suggesting a strong link between unproductive splicing and the abundance of functional transcripts...
  18. pmc Origin and evolution of Kinesin-like calmodulin-binding protein
    Salah E Abdel-Ghany
    Department of Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Plant Physiol 138:1711-22. 2005
    ....
  19. ncbi request reprint Organ-specific, developmental, hormonal and stress regulation of expression of putative pectate lyase genes in Arabidopsis
    Saiprasad Goud Palusa
    Department of Biology and Program in Molecular Plant Biology, Colorado State University, Fort Collins, CO 80523 1878, USA
    New Phytol 174:537-50. 2007
    ..The stability of transcripts of PLLs varied considerably among different genes. Our results indicate a complex regulation of expression of PLLs and involvement of PLLs in some of the hormonal and stress responses...
  20. pmc Comprehensive comparative analysis of kinesins in photosynthetic eukaryotes
    Dale N Richardson
    Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
    BMC Genomics 7:18. 2006
    ....
  21. ncbi request reprint Alternative splicing of pre-messenger RNAs in plants in the genomic era
    Anireddy S N Reddy
    Department of Biology and Program in Molecular Plant Biology, Colorado State University, Fort Collins, CO 80523, USA
    Annu Rev Plant Biol 58:267-94. 2007
    ..Recent studies suggest that alternative splicing in plants is an important posttranscriptional regulatory mechanism in modulating gene expression and eventually plant form and function...
  22. doi request reprint Plant serine/arginine-rich proteins: roles in precursor messenger RNA splicing, plant development, and stress responses
    Anireddy S N Reddy
    Department of Biology, Program in Molecular Plant Biology, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO, USA
    Wiley Interdiscip Rev RNA 2:875-89. 2011
    ..Here, we discuss the current status of research on plant SRs and some promising approaches to address many unanswered questions about plant SRs...
  23. pmc Coping with stresses: roles of calcium- and calcium/calmodulin-regulated gene expression
    Anireddy S N Reddy
    Department of Biology, Program in Molecular Plant Biology, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Plant Cell 23:2010-32. 2011
    ..We will discuss emerging paradigms in the field, highlight the areas that need further investigation, and present some promising novel high-throughput tools to address Ca(2+)-regulated transcriptional networks...
  24. pmc The plant U1 small nuclear ribonucleoprotein particle 70K protein interacts with two novel serine/arginine-rich proteins
    M Golovkin
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Plant Cell 10:1637-48. 1998
    ..Our results suggest that the plant SRZ proteins represent a new group of SR proteins. The interaction of plant U1-70K with the SRZ proteins may account for some differences in pre-mRNA splicing between plants and animals...
  25. doi request reprint Interactions of SR45, an SR-like protein, with spliceosomal proteins and an intronic sequence: insights into regulated splicing
    Irene S Day
    Department of Biology, Program in Molecular Plant Biology, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Plant J 71:936-47. 2012
    ..These results suggest that SR45 recruits U1snRNP and U2AF to 5' and 3' splice sites, respectively, by interacting with pre-mRNA, U1-70K and U2AF(35) and modulates AS...
  26. pmc A calmodulin-binding protein from Arabidopsis has an essential role in pollen germination
    Maxim Golovkin
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1878, USA
    Proc Natl Acad Sci U S A 100:10558-63. 2003
    ..Our genetic, histological, and pollen germination studies with the knockout mutant line indicate that NPG1 is not necessary for microsporogenesis and gametogenesis but is essential for pollen germination...
  27. ncbi request reprint Proteomics of calcium-signaling components in plants
    Vaka S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, 200 West Lake Street, Fort Collins, CO 80523, USA
    Phytochemistry 65:1745-76. 2004
    ..Here we discuss the current status of Ca2+ signaling components, their known functions and potential of emerging high-throughput genomic and proteomic technologies in unraveling complex Ca2+ circuitry...
  28. ncbi request reprint Nuclear localization and in vivo dynamics of a plant-specific serine/arginine-rich protein
    Gul Shad Ali
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA
    Plant J 36:883-93. 2003
    ..These results indicate that transcription activity of the cell and protein (de)phosphorylation regulate the intranuclear distribution of SR45...
  29. pmc Structure and expression of a plant U1 snRNP 70K gene: alternative splicing of U1 snRNP 70K pre-mRNAs produces two different transcripts
    M Golovkin
    Department of Biology, Colorado State University, Fort Collins 80523, USA
    Plant Cell 8:1421-35. 1996
    ..In addition, multiple polyadenylation sites were observed in the 3' untranslated region. These results suggest a complex post-transcriptional regulation of Arabidopsis U1-70K gene expression...
  30. ncbi request reprint Interaction of a kinesin-like calmodulin-binding protein with a protein kinase
    I S Day
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 275:13737-45. 2000
    ..The association of KIPK with KCBP suggests regulation of KCBP or KCBP-associated proteins by phosphorylation and/or that KCBP is involved in targeting KIPK to its proper cellular location...
  31. pmc Expression of U1 small nuclear ribonucleoprotein 70K antisense transcript using APETALA3 promoter suppresses the development of sepals and petals
    Maxim Golovkin
    Department of Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    Plant Physiol 132:1884-91. 2003
    ..Flowers of Arabidopsis plants transformed with a reporter gene driven by the same promoter showed no abnormalities. These results show that U1-70K is necessary for the development of sepals and petals and is an essential gene in plants...
  32. pmc Arabidopsis thaliana VOZ (Vascular plant One-Zinc finger) transcription factors are required for proper regulation of flowering time
    Helena Celesnik
    Department of Biology, Program in Molecular Plant Biology, Program in Cell and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1878, USA
    Biol Open 2:424-31. 2013
    ....
  33. ncbi request reprint Cloning of the cDNA for glutamyl-tRNA synthetase from Arabidopsis thaliana
    I S Day
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    Biochim Biophys Acta 1399:219-24. 1998
    ..Expression of the GluRSAt in E. coli resulted in a protein of the expected size. Comparison of the amino acid sequence GluRSAt to other glutamyl-tRNA synthetases showed strong sequence similarity to cytoplasmic GluRS proteins...
  34. doi request reprint Metabolic engineering of Arabidopsis for butanetriol production using bacterial genes
    Salah E Abdel-Ghany
    Department of Biology and Program in Molecular Plant Biology, Colorado State University, Fort Collins, CO 80523 1878, USA
    Metab Eng 20:109-20. 2013
    ..This proof-of-concept study for phytoproduction of butanetriol paves the way to further manipulate metabolic pathways in plants to enhance the level of butanetriol production. ..
  35. pmc Deciphering the plant splicing code: experimental and computational approaches for predicting alternative splicing and splicing regulatory elements
    Anireddy S N Reddy
    Program in Molecular Plant Biology, Department of Biology, Colorado State University Fort Collins, CO, USA
    Front Plant Sci 3:18. 2012
    ..Such studies will permit identification of plant-specific features involved in AS regulation and contribute to deciphering the splicing code in plants...
  36. ncbi request reprint An SC35-like protein and a novel serine/arginine-rich protein interact with Arabidopsis U1-70K protein
    M Golovkin
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Biol Chem 274:36428-38. 1999
    ..The interaction of plant U1-70K with a novel set of proteins suggests the early stages of spliceosome assembly, and intron recognition in plants is likely to be different from animals...
  37. ncbi request reprint Molecular motors and their functions in plants
    A S Reddy
    Department of Biology and Program in Cell and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    Int Rev Cytol 204:97-178. 2001
    ..Structural features of some plant motors suggest calcium, through calmodulin, is likely to play a key role in regulating the function of both microtubule- and actin-based motors in plants...
  38. doi request reprint Structural dynamics of the microtubule binding and regulatory elements in the kinesin-like calmodulin binding protein
    Maia V Vinogradova
    Department of Biochemistry Biophysics, University of California, 600 16th Street GH S412E, San Francisco, CA 94107, USA
    J Struct Biol 163:76-83. 2008
    ..The observed variations in the position of the calmodulin binding helix fit the regulatory mechanism previously proposed for this kinesin motor...
  39. pmc Alternative splicing at NAGNAG acceptors in Arabidopsis thaliana SR and SR-related protein-coding genes
    Stefanie Schindler
    Genome Analysis, Leibniz Institute for Age Research Fritz Lipmann Institute, Beutenbergstr 11, 07745 Jena, Germany
    BMC Genomics 9:159. 2008
    ..As SR proteins, a family of RRM-containing important splicing factors, are known to be extensively alternatively spliced in Arabidopsis, we analyzed alternative splicing at NAGNAG acceptors in SR and SR-related genes...
  40. ncbi request reprint Crystal structure of kinesin regulated by Ca(2+)-calmodulin
    Maia V Vinogradova
    Department of Biochemistry Biophysics, University of California, San Francisco, California 94143 2240, USA
    J Biol Chem 279:23504-9. 2004
    ..Together with biochemical data, the crystal structure suggests that Ca(2+)-calmodulin inhibits the binding of KCBP to microtubules by blocking the microtubule-binding sites on KCBP...
  41. pmc A standardized kinesin nomenclature
    Carolyn J Lawrence
    Department of Plant Biology, The University of Georgia, Athens, GA 30602, USA
    J Cell Biol 167:19-22. 2004
    ..The scheme unifies all previous phylogenies and nomenclature proposals, while allowing individual sequence names to remain the same, and for expansion to occur as new sequences are discovered...