Research Topics
| Andrey A PtitsynSummaryAffiliation: Colorado State University Country: USA Publications
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Detail Information
Publications
Circadian clocks are resounding in peripheral tissuesAndrey A Ptitsyn
Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, Baton Rouge, Louisiana, USA
PLoS Comput Biol 2:e16. 2006..We conclude that greater attention should be given to the potential influence of circadian mechanisms on any biological pathway related to metabolism and obesity...- Transformation of metabolism with age and lifestyle in Antarctic seals: a case study of systems biology approach to cross-species microarray experimentAndrey Ptitsyn
Colorado State University Department of Biology, Fort Collins, CO 80523, USA
BMC Syst Biol 4:133. 2010..However, the analysis of gene expression in seals is hampered by the lack of specific microarrays and the very limited annotation of known Weddell seal (Leptonychotes weddellii) genes... - Small RNA profiling of Dengue virus-mosquito interactions implicates the PIWI RNA pathway in anti-viral defenseAnn M Hess
Department of Statistics, Colorado State University, Fort Collins, Colorado 80523, USA
BMC Microbiol 11:45. 2011..aegypti, we deep-sequenced small non-coding RNAs. Triplicate biological replicates were used so that rigorous statistical metrics could be applied... - Systems biology approach to identification of biomarkers for metastatic progression in cancerAndrey A Ptitsyn
Center for Bioinformatics, Department of Microbiology, Immunology and Pathology, Colorado State University, Colorado, USA
BMC Bioinformatics 9:S8. 2008..Previous studies of gene expression patterns in metastasis have concentrated on selection of a small number of "signature" biomarkers... - Comprehensive analysis of circadian periodic pattern in plant transcriptomeAndrey Ptitsyn
Center for Bioinformatics, Department of Microbiology, Immunology and Pathology, Colorado State University, Campus delivery 1682 Fort Collins, CO 80523, USA
BMC Bioinformatics 9:S18. 2008..Circadian rhythm is a crucial factor in orchestration of plant physiology, keeping it in synchrony with the daylight cycle. Previous studies have reported that up to 16% of plant transcriptome are circadially expressed... - Stochastic resonance reveals "pilot light" expression in mammalian genesAndrey Ptitsyn
Center for Bioinformatics, Department of Microbiology, Immunology and Pathology, College of Veterinary and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America
PLoS ONE 3:e1842. 2008..The resolution ability of this method is limited by the background noise. Low expressed genes are detected with insufficient reliability and expression of many genes is never detected at all... - Analysis of circadian pattern reveals tissue-specific alternative transcription in leptin signaling pathwayAndrey A Ptitsyn
Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
BMC Bioinformatics 8:S15. 2007..It has been previously reported that most mammalian genes display a circadian oscillation in their baseline expression. Consequently, the phase and amplitude of each component of a signal transduction cascade has downstream consequences... - Digital signal processing reveals circadian baseline oscillation in majority of mammalian genesAndrey A Ptitsyn
Department of Microbiology, Immunology and Pathology, College of Veterinary and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America
PLoS Comput Biol 3:e120. 2007..Changes in gene expression caused by mutations or regulation of environmental factors (such as photic stimuli or feeding) should be considered in the context of changes in the amplitude and phase of genetic oscillations... 
True or false: all genes are rhythmicAndrey A Ptitsyn
Center for Bioinformatics, Colorado State University, Fort Collins, CO 80525, USA
Ann Med 43:1-12. 2011....- Unsupervised clustering of gene expression data points at hypoxia as possible trigger for metabolic syndromeAndrey Ptitsyn
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA
BMC Genomics 7:318. 2006..Classification of large volumes of data produced in a microarray experiment allows for the extraction of important clues as to the nature of a disease... - Computational analysis of gene expression space associated with metastatic cancerAndrey Ptitsyn
Center for Bioinformatics, Department of Microbiology, Immunology and Pathology, Colorado State University, Campus delivery 1682 Fort Collins, CO 80523, USA
BMC Bioinformatics 10:S6. 2009..A number of recent studies have identified multiple biomarkers for metastatic progression. However, most of the studies consider only direct comparison between metastatic and non-metastatic classes of samples... 
Characterization of peripheral circadian clocks in adipose tissuesSanjin Zvonic
Stem Cell Laboratory, Louisiana State University, Pennington Biomedical Research Center, Baton Rouge, LA, USA
Diabetes 55:962-70. 2006....- Permutation test for periodicity in short time series dataAndrey A Ptitsyn
Experimental Obesity Laboratory, Louisiana State University Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge, LA 70808, USA
BMC Bioinformatics 7:S10. 2006..The data produced in these experiments carries a high degree of stochastic variation, obscuring the periodic pattern and a limited number of replicates, typically covering not more than two complete periods of oscillation... - A systems biology approach to identify molecular pathways altered by HDAC inhibition in osteosarcomaLuke A Wittenburg
Animal Cancer Center, Department of Clinical Sciences, Colorado State University Animal Cancer Center, 300 W Drake Rd, Fort Collins, Colorado 80523 1620, USA
J Cell Biochem 113:773-83. 2012.... - Circadian rhythms in adipose tissue: an updateJeffrey M Gimble
Stem Cell Biology Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA
Curr Opin Clin Nutr Metab Care 14:554-61. 2011..This review highlights recent in-vitro and in-vivo findings from murine, human and model organism studies... - Maternal and fetal response to fetal persistent infection with bovine viral diarrhea virusThomas R Hansen
Animal Reproduction and Biotechnology Laboratory, Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
Am J Reprod Immunol 64:295-306. 2010..This results in induction of immune tolerance to the infecting BVDV strain and persistent infection (PI)... - Rhythms and synchronization patterns in gene expression in the Aedes aegypti mosquitoAndrey A Ptitsyn
Center for Bioinformatics, Colorado State University, Fort Collins, CO 80525, USA
BMC Genomics 12:153. 2011..Circadian gene expression in mosquito species has been previously reported but for only a few genes directly involved in the function of the molecular clock... - Yield and characterization of subcutaneous human adipose-derived stem cells by flow cytometric and adipogenic mRNA analyzesGang Yu
Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA
Cytotherapy 12:538-46. 2010..This study reports our recent experience of isolating and immunophenotypically characterizing ASC from >60 human patients with a mean age of 43.6 and body mass index (BMI) of 27... - Prospective influences of circadian clocks in adipose tissue and metabolismJeffrey M Gimble
Stem Cell Biology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Nat Rev Endocrinol 7:98-107. 2011..Thus, circadian mechanisms represent a novel putative target for therapy in patients with metabolic diseases... - Expression profiling in canine osteosarcoma: identification of biomarkers and pathways associated with outcomeLiza E O'Donoghue
Department of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA
BMC Cancer 10:506. 2010..Unfortunately, OSA is an aggressive cancer with a high metastatic rate. Characterization of OSA with regard to its metastatic potential and chemotherapeutic resistance will improve both prognostic capabilities and treatment modalities... - Persistent fetal infection with bovine viral diarrhea virus differentially affects maternal blood cell signal transduction pathwaysNatalia P Smirnova
Department of Biomedical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523 1683, USA
Physiol Genomics 36:129-39. 2009.... - Circadian expression of genes regulating food intakeAdrian M Stütz
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA
Obesity (Silver Spring) 15:607-15. 2007..In the present study, we examined the circadian expression profiles of these genes... - Class discovery analysis of the lung cancer gene expression dataAndrey Ptitsyn
Pennington Biomedical Research Center, Baton Rouge, Louisiana 70808, USA
DNA Cell Biol 23:715-21. 2004..These subtypes should be taken into account in diagnostics, drug testing, and treatment development for lung cancer patients... - CLU: a new algorithm for EST clusteringAndrey Ptitsyn
Pennington Biomedical Research Center, 6400 Perkins Rd, Baton Rouge LA 70808, USA
BMC Bioinformatics 6:S3. 2005..Clustered EST data, accumulated in databases such as UniGene, STACK and TIGR Gene Indices have proven to be crucial in research areas from gene discovery to regulation of gene expression... - Circadian oscillation of gene expression in murine calvarial boneSanjin Zvonic
Stem Cell Biology Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge 70808, USA
J Bone Miner Res 22:357-65. 2007..Thus, circadian mechanisms may directly modulate oxidative phosphorylation and multiple metabolic pathways in bone homeostasis...