OLVE BREIEN PEERSEN

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. pmc Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts
    Peng Gong
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e60272. 2013
  2. ncbi request reprint Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA
    Olve B Peersen
    University of Colorado, Department of Chemistry and Biochemistry, Boulder, Colorado 80309 0215 USA
    Nat Struct Biol 9:182-7. 2002
  3. pmc That zincing feeling: the effects of EDTA on the behaviour of zinc-binding transcriptional regulators
    Jennifer K Nyborg
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Biochem J 381:e3-4. 2004
  4. pmc Analysis of flavivirus NS5 methyltransferase cap binding
    Brian J Geiss
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Mol Biol 385:1643-54. 2009
  5. ncbi request reprint Self-association of the yeast nucleosome assembly protein 1
    Steven J McBryant
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    Biochemistry 43:10592-9. 2004
  6. pmc Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
    Aaron A Thompson
    Program in Cellular and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    EMBO J 23:3462-71. 2004
  7. ncbi request reprint Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer
    Andres B Tellez
    Department of Biomedical Informatics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Mol Biol 357:665-75. 2006
  8. pmc Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions
    Aaron A Thompson
    Program in Cellular and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    J Mol Biol 366:1459-74. 2007

Research Grants

  1. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2004
  2. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2005
  3. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2006
  4. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2007
  5. Assembly of Picornaviral Replication Complexes
    OLVE BREIEN PEERSEN; Fiscal Year: 2010

Collaborators

  • JENNIFER NYBORG
  • Brian J Geiss
  • Aaron A Thompson
  • Peng Gong
  • Andres B Tellez
  • Steven J McBryant
  • Jay C Nix
  • Ralph E Davis
  • Matthew G Kortus
  • Rebecca A Albertini
  • Scott Crowder
  • Jeannie F Spagnolo
  • Douglas L Brutlag
  • Karla Kirkegaard

Detail Information

Publications8

  1. pmc Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts
    Peng Gong
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 8:e60272. 2013
    ....
  2. ncbi request reprint Dimeric structure of the Oxytricha nova telomere end-binding protein alpha-subunit bound to ssDNA
    Olve B Peersen
    University of Colorado, Department of Chemistry and Biochemistry, Boulder, Colorado 80309 0215 USA
    Nat Struct Biol 9:182-7. 2002
    ....
  3. pmc That zincing feeling: the effects of EDTA on the behaviour of zinc-binding transcriptional regulators
    Jennifer K Nyborg
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    Biochem J 381:e3-4. 2004
    ....
  4. pmc Analysis of flavivirus NS5 methyltransferase cap binding
    Brian J Geiss
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Mol Biol 385:1643-54. 2009
    ..A detailed model of how the flavivirus MTase protein binds RNA cap structures is presented...
  5. ncbi request reprint Self-association of the yeast nucleosome assembly protein 1
    Steven J McBryant
    Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523 1870, USA
    Biochemistry 43:10592-9. 2004
    ..Dissociation of the dimer requires a nearly complete denaturation event...
  6. pmc Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
    Aaron A Thompson
    Program in Cellular and Molecular Biology, Colorado State University, Fort Collins 80523, USA
    EMBO J 23:3462-71. 2004
    ..This sensitivity is the result of allosteric effects where the structure around the buried N-terminus directly affects the positioning of Asp238 in the active site...
  7. ncbi request reprint Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer
    Andres B Tellez
    Department of Biomedical Informatics, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Mol Biol 357:665-75. 2006
    ....
  8. pmc Stabilization of poliovirus polymerase by NTP binding and fingers-thumb interactions
    Aaron A Thompson
    Program in Cellular and Molecular Biology, Colorado State University, Fort Collins, CO 80523 1870, USA
    J Mol Biol 366:1459-74. 2007
    ..The role of the enclosed active site motif as a structural scaffold for constraining the fingers domain and accommodating conformational changes in 3D(pol) and other viral polymerases during the catalytic cycle is discussed...

Research Grants6

  1. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2004
    ..The results will yield fundamental insights into the replication of this important group of pathogens. ..
  2. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2005
    ..The results will yield fundamental insights into the replication of this important group of pathogens. ..
  3. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2006
    ..The results will yield fundamental insights into the replication of this important group of pathogens. ..
  4. Assembly of Picornaviral Replication Complexes
    Olve Peersen; Fiscal Year: 2007
    ..The results will yield fundamental insights into the replication of this important group of pathogens. ..
  5. Assembly of Picornaviral Replication Complexes
    OLVE BREIEN PEERSEN; Fiscal Year: 2010
    ..The focus of this research project is to understand how this protein functions during virus replication and find ways to interfere with its function, which can open the door to the development of antiviral drugs. ..