K R Magnusson

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi request reprint The aging of the NMDA receptor complex
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Front Biosci 3:e70-80. 1998
  2. ncbi request reprint Aging of glutamate receptors: correlations between binding and spatial memory performance in mice
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80526, USA
    Mech Ageing Dev 104:227-48. 1998
  3. ncbi request reprint Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor
    K R Magnusson
    Department of Anatomy, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523 1670, USA
    J Neurosci 20:1666-74. 2000
  4. ncbi request reprint Changes in anesthetic sensitivity and glutamate receptors in the aging canine brain
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523 1670, USA
    J Gerontol A Biol Sci Med Sci 55:B448-54. 2000
  5. ncbi request reprint Influence of diet restriction on NMDA receptor subunits and learning during aging
    K R Magnusson
    Department of Anatomy and Neurobiology, Program in Molecular, Cellular, and Integrative Neurosciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1670, USA
    Neurobiol Aging 22:613-27. 2001
  6. ncbi request reprint Differential effects of aging on binding sites of the activated NMDA receptor complex in mice
    K R Magnusson
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Mech Ageing Dev 84:227-43. 1995
  7. ncbi request reprint The effects of age and dietary restriction on metabotropic glutamate receptors in C57B1 mice
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, USA
    J Gerontol A Biol Sci Med Sci 52:B291-9. 1997
  8. ncbi request reprint Electrophysiological analysis of NMDA receptor subunit changes in the aging mouse cortex
    M C Kuehl-Kovarik
    Department of Anatomy and Neurobiology, Colorado State University, Ft Collins, CO 80523, USA
    Mech Ageing Dev 115:39-59. 2000

Collaborators

Detail Information

Publications8

  1. ncbi request reprint The aging of the NMDA receptor complex
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Front Biosci 3:e70-80. 1998
    ..These studies suggest that the development of treatments that are aimed at preventing or reversing the effects of aging on the NMDA receptor will aid in preventing the memory declines that are associated with aging...
  2. ncbi request reprint Aging of glutamate receptors: correlations between binding and spatial memory performance in mice
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80526, USA
    Mech Ageing Dev 104:227-48. 1998
    ..These results suggest that there is a sparing of spatial memory with diet restriction in aging C57B1/6 mice and that the effects of aging on NMDA and AMPA receptors may be associated with age-related declines in spatial learning...
  3. ncbi request reprint Declines in mRNA expression of different subunits may account for differential effects of aging on agonist and antagonist binding to the NMDA receptor
    K R Magnusson
    Department of Anatomy, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523 1670, USA
    J Neurosci 20:1666-74. 2000
    ..These results suggest that changes during aging in the expression of different subunits of the NMDA receptor may account for the differential effects of aging on agonist versus antagonist binding to the NMDA binding site...
  4. ncbi request reprint Changes in anesthetic sensitivity and glutamate receptors in the aging canine brain
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523 1670, USA
    J Gerontol A Biol Sci Med Sci 55:B448-54. 2000
    ....
  5. ncbi request reprint Influence of diet restriction on NMDA receptor subunits and learning during aging
    K R Magnusson
    Department of Anatomy and Neurobiology, Program in Molecular, Cellular, and Integrative Neurosciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1670, USA
    Neurobiol Aging 22:613-27. 2001
    ..This suggests that it is the relationship between subunit expression levels that is important for maintaining memory functions in older animals...
  6. ncbi request reprint Differential effects of aging on binding sites of the activated NMDA receptor complex in mice
    K R Magnusson
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Mech Ageing Dev 84:227-43. 1995
    ..These results suggest that aging has heterogeneous effects on different sites on the NMDA receptor complex throughout the brain and on NMDA receptor agonist versus antagonist binding in selected brain regions...
  7. ncbi request reprint The effects of age and dietary restriction on metabotropic glutamate receptors in C57B1 mice
    K R Magnusson
    Department of Anatomy and Neurobiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, USA
    J Gerontol A Biol Sci Med Sci 52:B291-9. 1997
    ..These results suggest that dietary restriction induces a decrease in one or more of the functions associated with met2 binding sites during the aging process...
  8. ncbi request reprint Electrophysiological analysis of NMDA receptor subunit changes in the aging mouse cortex
    M C Kuehl-Kovarik
    Department of Anatomy and Neurobiology, Colorado State University, Ft Collins, CO 80523, USA
    Mech Ageing Dev 115:39-59. 2000
    ..Results are consistent with the interpretation that the epsilon2 subunit is reduced in older mouse frontal cortex. A change in NMDA receptor subunit composition could influence memory processes during aging...