Sue C Kinnamon

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. pmc Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25
    Tod R Clapp
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    BMC Biol 4:7. 2006
  2. doi request reprint Receptors and transduction of umami taste stimuli
    Sue C Kinnamon
    Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Ann N Y Acad Sci 1170:55-9. 2009
  3. ncbi request reprint Downstream signaling effectors for umami taste
    Sue C Kinnamon
    Department of Biomedical Sciences, Division of Neuroscience, Colorado State University, Fort Collins, CO 80523, USA
    Chem Senses 30:i31-2. 2005
  4. ncbi request reprint Detection of NaCl and KCl in TRPV1 knockout mice
    Collin Ruiz
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Chem Senses 31:813-20. 2006
  5. pmc Amiloride-sensitive channels in type I fungiform taste cells in mouse
    Aurelie Vandenbeuch
    Department of Biomedical Science, Colorado State University, Fort Collins, USA
    BMC Neurosci 9:1. 2008
  6. ncbi request reprint Behavioral evidence for a role of alpha-gustducin in glutamate taste
    Collin J Ruiz
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Chem Senses 28:573-9. 2003
  7. pmc Tonic activity of Galpha-gustducin regulates taste cell responsivity
    Tod R Clapp
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States
    FEBS Lett 582:3783-7. 2008
  8. ncbi request reprint Responses to di-sodium guanosine 5'-monophosphate and monosodium L-glutamate in taste receptor cells of rat fungiform papillae
    Weihong Lin
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Neurophysiol 89:1434-9. 2003
  9. ncbi request reprint Electrophysiological characterization of voltage-gated currents in defined taste cell types of mice
    Kathryn F Medler
    Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    J Neurosci 23:2608-17. 2003
  10. ncbi request reprint Morphologic characterization of rat taste receptor cells that express components of the phospholipase C signaling pathway
    Tod R Clapp
    Department of Biomedical Sciences, Anatomy and Neurobiology Section, Colorado State University, Fort Collins, Colorado 80523, USA
    J Comp Neurol 468:311-21. 2004

Collaborators

Detail Information

Publications20

  1. pmc Mouse taste cells with G protein-coupled taste receptors lack voltage-gated calcium channels and SNAP-25
    Tod R Clapp
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    BMC Biol 4:7. 2006
    ....
  2. doi request reprint Receptors and transduction of umami taste stimuli
    Sue C Kinnamon
    Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    Ann N Y Acad Sci 1170:55-9. 2009
    ..In most taste fields, however, cAMP antagonizes responses to umami stimuli, suggesting that the Galpha subunit serves to modulate umami taste sensitivity...
  3. ncbi request reprint Downstream signaling effectors for umami taste
    Sue C Kinnamon
    Department of Biomedical Sciences, Division of Neuroscience, Colorado State University, Fort Collins, CO 80523, USA
    Chem Senses 30:i31-2. 2005
  4. ncbi request reprint Detection of NaCl and KCl in TRPV1 knockout mice
    Collin Ruiz
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Chem Senses 31:813-20. 2006
    ..These data, taken together, suggest that additional mechanisms must contribute to the amiloride-insensitive NaCl response...
  5. pmc Amiloride-sensitive channels in type I fungiform taste cells in mouse
    Aurelie Vandenbeuch
    Department of Biomedical Science, Colorado State University, Fort Collins, USA
    BMC Neurosci 9:1. 2008
    ..We also used immunocytochemistry to further define and compare cell types in fungiform and circumvallate taste buds of these mice...
  6. ncbi request reprint Behavioral evidence for a role of alpha-gustducin in glutamate taste
    Collin J Ruiz
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Chem Senses 28:573-9. 2003
    ..These data suggest that alpha-gustducin plays a role in glutamate taste...
  7. pmc Tonic activity of Galpha-gustducin regulates taste cell responsivity
    Tod R Clapp
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States
    FEBS Lett 582:3783-7. 2008
    ..We propose that an important role of alpha-gus is to maintain cAMP levels tonically low to ensure adequate Ca2+ signaling...
  8. ncbi request reprint Responses to di-sodium guanosine 5'-monophosphate and monosodium L-glutamate in taste receptor cells of rat fungiform papillae
    Weihong Lin
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Neurophysiol 89:1434-9. 2003
    ..Together, our results suggest that intracellular cAMP- and Ca(2+)-mediated pathways are involved in umami taste transduction for GMP and its synergistic responses with glutamate...
  9. ncbi request reprint Electrophysiological characterization of voltage-gated currents in defined taste cell types of mice
    Kathryn F Medler
    Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado 80523, USA
    J Neurosci 23:2608-17. 2003
    ..Unexpectedly, all gustducin-expressing cells lacked voltage-gated Ca(2+) currents, suggesting that these cells use mechanisms other than classical synapses to communicate signals to the brain...
  10. ncbi request reprint Morphologic characterization of rat taste receptor cells that express components of the phospholipase C signaling pathway
    Tod R Clapp
    Department of Biomedical Sciences, Anatomy and Neurobiology Section, Colorado State University, Fort Collins, Colorado 80523, USA
    J Comp Neurol 468:311-21. 2004
    ..We speculate that some type II cells may communicate to the nervous system via subsurface cisternae of smooth endoplasmic reticulum in lieu of conventional synapses...
  11. pmc Umami taste transduction mechanisms
    Sue C Kinnamon
    Department of Biomedical Sciences, Colorado State University, Fort Collins, 80523, USA
    Am J Clin Nutr 90:753S-755S. 2009
    ....
  12. ncbi request reprint Acid-activated cation currents in rat vallate taste receptor cells
    Weihong Lin
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins, 80523, USA
    J Neurophysiol 88:133-41. 2002
    ..The large amplitude of the current and its existence in a high percentage of taste cells imply that ASICs or ASIC-like channels may play a prominent role in sour-taste transduction...
  13. ncbi request reprint Expression of T1Rs and gustducin in palatal taste buds of mice
    Leslie M Stone
    Rocky Mountain Taste and Smell Center, Aurora, CO 80045, USA
    Chem Senses 32:255-62. 2007
    ..T1R1-positive palate taste cells coexpress gustducin about half the time, suggesting that other G proteins may contribute to the transduction of umami stimuli in this taste field...
  14. ncbi request reprint Taste receptor cell responses to the bitter stimulus denatonium involve Ca2+ influx via store-operated channels
    Tatsuya Ogura
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Neurophysiol 87:3152-5. 2002
    ..These data suggest that SOCs may contribute to bitter taste transduction and to regulation of Ca2+ homeostasis in taste cells...
  15. ncbi request reprint Virus-mediated transfer of foreign DNA into taste receptor cells
    Leslie M Stone
    Department of Biomedical Sciences, Colorado State University, Fort Collins 80523, USA
    Chem Senses 27:779-87. 2002
    ....
  16. ncbi request reprint ATP signaling is crucial for communication from taste buds to gustatory nerves
    Thomas E Finger
    Rocky Mountain Taste and Smell Center, Aurora CO 80045, USA
    Science 310:1495-9. 2005
    ..Finally, stimulation of taste buds in vitro evokes release of ATP. Thus, ATP fulfils the criteria for a neurotransmitter linking taste buds to the nervous system...
  17. pmc Nasal solitary chemoreceptor cell responses to bitter and trigeminal stimulants in vitro
    Brian D Gulbransen
    Rocky Mountain Taste and Smell Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    J Neurophysiol 99:2929-37. 2008
    ..Our results demonstrate that TRPM5- and gustducin-expressing nasal SCCs respond to the T2R agonist denatonium via a PLC-coupled transduction cascade typical of T2Rs in the taste system...
  18. ncbi request reprint Making sense with TRP channels: store-operated calcium entry and the ion channel Trpm5 in taste receptor cells
    Cristian A Perez
    Department of Physiology and Biophysics, Howard Hughes Medical Institute, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA
    Cell Calcium 33:541-9. 2003
    ..The role of store-operated channels and Trpm5 in capacitative calcium entry in taste receptor cells in response to bitter compounds is discussed...
  19. ncbi request reprint Tastants evoke cAMP signal in taste buds that is independent of calcium signaling
    Kristina R Trubey
    Dept of Physiology and Biophysics R430 Univ of Miami Miller School of Medicine, 1600 NW 10th Ave, Miami, FL 33136, USA
    Am J Physiol Cell Physiol 291:C237-44. 2006
    ..Our results suggest that tastant-evoked cAMP signals are not simply a secondary consequence of calcium modulation. Instead, cAMP and released Ca2+ may represent independent second messenger signals downstream of taste receptors...
  20. ncbi request reprint TRPV1 receptors and nasal trigeminal chemesthesis
    Wayne L Silver
    Department of Biology, Wake Forest University, Winston Salem, NC 27106, USA
    Chem Senses 31:807-12. 2006
    ..These results suggest that TRPV1 serves as a receptor for both cyclohexanone and capsaicin in trigeminal nerve endings...