S Dow

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi request reprint Changes in regulatory T cells in dogs with cancer and associations with tumor type
    K O'Neill
    Department of Clinical Sciences, Animal Cancer Center, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Intern Med 23:875-81. 2009
  2. pmc An improved selective culture medium enhances the isolation of Burkholderia pseudomallei from contaminated specimens
    Andrew Goodyear
    Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, Colorado State University, Fort Collins, Colorado Department of Biology, North Park University, Chicago, Illinois Lao Oxford Mahosot Hospital Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People s Democratic Republic Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
    Am J Trop Med Hyg 89:973-82. 2013
  3. pmc Persistent gastric colonization with Burkholderia pseudomallei and dissemination from the gastrointestinal tract following mucosal inoculation of mice
    Andrew Goodyear
    Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center for Excellence for Biodefense and Emerging Infectious Diseases Research, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 7:e37324. 2012
  4. doi request reprint Increased monocyte chemotactic protein-1 concentration and monocyte count independently associate with a poor prognosis in dogs with lymphoma
    J A Perry
    Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Vet Comp Oncol 9:55-64. 2011
  5. doi request reprint Anti-endothelial cell antibodies in dogs with immune-mediated hemolytic anemia and other diseases associated with high risk of thromboembolism
    R Wells
    Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Intern Med 23:295-300. 2009
  6. pmc Liposome-nucleic acid immunotherapeutics
    Steven Dow
    Department of Microbiology, Colorado State University, Ft Collins, CO 80523, USA
    Expert Opin Drug Deliv 5:11-24. 2008
  7. doi request reprint Anti-erythrocyte antibodies and disease associations in anemic and nonanemic dogs
    P Morley
    Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Intern Med 22:886-92. 2008
  8. ncbi request reprint Use of flow cytometry and monochlorobimane to quantitate intracellular glutathione concentrations in feline leukocytes
    Craig Webb
    Department of Clinical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    Vet Immunol Immunopathol 112:129-40. 2006
  9. ncbi request reprint Neutrophil function in septic dogs
    Craig Webb
    Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    J Vet Intern Med 21:982-9. 2007
  10. ncbi request reprint Oxidative stress during acute FIV infection in cats
    Craig Webb
    Department of Clinical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    Vet Immunol Immunopathol 122:16-24. 2008

Collaborators

  • Yong Liu
  • Craig B Webb
  • Herbert Schweizer
  • S Rao
  • D H Thamm
  • T Hackett
  • Cheryl London
  • Daniel Gustafson
  • Andrew Goodyear
  • A Guth
  • Scott Hafeman
  • Robyn Elmslie
  • Debra Kamstock
  • Karen Sellins
  • A G Miller
  • J A Perry
  • Helle Bielefeldt-Ohmann
  • Bruce Pulford
  • Abby Jones
  • LANCE U'REN
  • A Duffy
  • R Wells
  • K O'Neill
  • Catharine Bosio
  • P Morley
  • Amanda Guth
  • R Elmslie
  • Susan Lana
  • L U'REN
  • D Kamstock
  • Michael Jordan
  • Karen Zaks
  • Mark Mathes
  • David A B Dance
  • Linda Strange
  • Joy Silisouk
  • Drew A Rholl
  • C S Olver
  • L Long
  • A C Avery
  • J Eickhoff
  • Angela Duffy
  • Alan Schenkel
  • Christian Julius
  • Jessica Veatch
  • A Christy Wyckoff
  • Aimee Bell
  • Genevieve Forster
  • Crystal Meyerett
  • Jan Kranich
  • Theodore Johnson
  • Heather Bender
  • Martin Schriefer
  • Mark D Zabel
  • Brady Michel
  • Natalia Reim
  • G Ogilvie
  • Gino Miele
  • Ryan Troyer
  • Katie Propst
  • Lisa Kellihan
  • M Lappin
  • B Biller
  • M Mathes
  • Paul Morley
  • Susan Plaza
  • D Liggitt
  • R Kedl
  • I Kurzman
  • Angelo Izzo
  • L Coro
  • J Fairman
  • Ross Kedl
  • Denny Liggitt
  • Lee Fradkin

Detail Information

Publications27

  1. ncbi request reprint Changes in regulatory T cells in dogs with cancer and associations with tumor type
    K O'Neill
    Department of Clinical Sciences, Animal Cancer Center, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Intern Med 23:875-81. 2009
    ..However, Tregs have not been well studied in dogs with cancer and it is not known if certain tumor types are associated with increased Tregs...
  2. pmc An improved selective culture medium enhances the isolation of Burkholderia pseudomallei from contaminated specimens
    Andrew Goodyear
    Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center of Excellence for Biodefense and Emerging Infectious Diseases Research, Colorado State University, Fort Collins, Colorado Department of Biology, North Park University, Chicago, Illinois Lao Oxford Mahosot Hospital Wellcome Trust Research Unit, Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao People s Democratic Republic Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom
    Am J Trop Med Hyg 89:973-82. 2013
    ..Therefore, we conclude that NAP-A medium provides a new tool for more sensitive isolation of B. pseudomallei from heavily contaminated sites...
  3. pmc Persistent gastric colonization with Burkholderia pseudomallei and dissemination from the gastrointestinal tract following mucosal inoculation of mice
    Andrew Goodyear
    Department of Microbiology, Immunology, and Pathology, Rocky Mountain Regional Center for Excellence for Biodefense and Emerging Infectious Diseases Research, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 7:e37324. 2012
    ..pseudomallei preferentially colonizes the stomach following oral inoculation, and that the chronically colonized GI tract likely serves as a reservoir for dissemination of infection to extra-intestinal sites...
  4. doi request reprint Increased monocyte chemotactic protein-1 concentration and monocyte count independently associate with a poor prognosis in dogs with lymphoma
    J A Perry
    Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    Vet Comp Oncol 9:55-64. 2011
    ..The mechanisms underlying these observations remain to be determined...
  5. doi request reprint Anti-endothelial cell antibodies in dogs with immune-mediated hemolytic anemia and other diseases associated with high risk of thromboembolism
    R Wells
    Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Intern Med 23:295-300. 2009
    ..The presence of anti-endothelial cell autoantibodies (AECA) has been associated with an increased risk of thromboembolism in humans...
  6. pmc Liposome-nucleic acid immunotherapeutics
    Steven Dow
    Department of Microbiology, Colorado State University, Ft Collins, CO 80523, USA
    Expert Opin Drug Deliv 5:11-24. 2008
    ..Thus, liposome-nucleic acid complexes form a potent and versatile immunotherapeutic platform...
  7. doi request reprint Anti-erythrocyte antibodies and disease associations in anemic and nonanemic dogs
    P Morley
    Department of Clinical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Vet Intern Med 22:886-92. 2008
    ....
  8. ncbi request reprint Use of flow cytometry and monochlorobimane to quantitate intracellular glutathione concentrations in feline leukocytes
    Craig Webb
    Department of Clinical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    Vet Immunol Immunopathol 112:129-40. 2006
    ....
  9. ncbi request reprint Neutrophil function in septic dogs
    Craig Webb
    Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    J Vet Intern Med 21:982-9. 2007
    ....
  10. ncbi request reprint Oxidative stress during acute FIV infection in cats
    Craig Webb
    Department of Clinical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    Vet Immunol Immunopathol 122:16-24. 2008
    ..Further studies are required to determine whether early treatment with anti-oxidants may help ameliorate the decline in CD4(+) T cell number and function associated with acute FIV infection in cats...
  11. ncbi request reprint Hematologic improvement in dogs with parvovirus infection treated with recombinant canine granulocyte-colony stimulating factor
    A Duffy
    Department of Clinical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    J Vet Pharmacol Ther 33:352-6. 2010
    ....
  12. ncbi request reprint Liposome-DNA complexes infused intravenously inhibit tumor angiogenesis and elicit antitumor activity in dogs with soft tissue sarcoma
    D Kamstock
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft Collins, 80523, USA
    Cancer Gene Ther 13:306-17. 2006
    ..These results suggest that intravenous infusions of LDC may elicit nonspecific antitumor activity and inhibit tumor angiogenesis...
  13. ncbi request reprint Vaccination with liposome--DNA complexes elicits enhanced antitumor immunity
    L U'REN
    Department of Microbiology, Colorado State University, Ft Collins, CO 80523, USA
    Cancer Gene Ther 13:1033-44. 2006
    ....
  14. ncbi request reprint Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs
    Mark Mathes
    Departments of Clinical Sciences, Colorado State University, Ft Collins, CO 80523, USA
    Exp Hematol 34:1393-402. 2006
    ..Therefore, the safety and efficacy of LC treatment was assessed in normal dogs and in dogs with spontaneous autoimmune hemolytic anemia (AIHA)...
  15. doi request reprint Antiphospholipid antibodies in dogs with immune mediated hemolytic anemia, spontaneous thrombosis, and hyperadrenocorticism
    A G Miller
    Department of Microbiology, Immunology and Pathology, Colorado State University, 200 Lake Street, Fort Collins, CO 80523, USA
    J Vet Intern Med 26:614-23. 2012
    ..The pathophysiology of thrombus formation in canine IMHA and other diseases remains unclear. Antiphospholipid antibodies (aPL) are an important cause of thrombosis in humans and might cause thrombosis in dogs...
  16. ncbi request reprint Phase I study of liposome-DNA complexes encoding the interleukin-2 gene in dogs with osteosarcoma lung metastases
    Steven Dow
    Department of Clinical Sciences, Colorado State University, Fort Collins, 80523, USA
    Hum Gene Ther 16:937-46. 2005
    ..We conclude that repeated intravenous infusion of LDCs in cancerbearing dogs is safe and well tolerated at low doses and may be capable of eliciting antitumor activity in some animals with advanced tumor metastases...
  17. doi request reprint Evaluation of liposomal clodronate for treatment of malignant histiocytosis in dogs
    Scott Hafeman
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft Collins, 80523, USA
    Cancer Immunol Immunother 59:441-52. 2010
    ..These findings suggest that liposomal delivery of clodronate and possibly other bisphosphonates may offer an effective new approach to treatment of histiocytic neoplasms in dogs and humans...
  18. ncbi request reprint Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma
    Debra Kamstock
    Department of Microbiology, Colorado State University, Ft Collins, CO 80523, USA
    Cancer Immunol Immunother 56:1299-309. 2007
    ..The overall tumor response rate was 30% for all treated dogs in the study. We conclude therefore that a xenogeneic VEGF vaccine may be a safe and effective alternative means of controlling tumor growth and angiogenesis...
  19. pmc Protection from pneumonic infection with burkholderia species by inhalational immunotherapy
    Andrew Goodyear
    Department of Microbiology, Immunology and Pathology, Colorado State University, Ft Collins, CO 80523, USA
    Infect Immun 77:1579-88. 2009
    ..We concluded that the potent local activation of innate immune responses in the lung could be used to elicit rapid and nonspecific protection from aerosol exposure to both B. mallei and B. pseudomallei...
  20. ncbi request reprint Continuous low-dose oral chemotherapy for adjuvant therapy of splenic hemangiosarcoma in dogs
    Susan Lana
    Animal Cancer Center, Department of Clinical Sciences, Colorado State University, Ft Collins, 80523, USA
    J Vet Intern Med 21:764-9. 2007
    ..Therefore, we evaluated the safety and effectiveness of LDC using a combination of cyclophosphamide, etoposide, and piroxicam as adjuvant therapy for dogs with stage II HSA...
  21. pmc Type I interferons inhibit the generation of tumor-associated macrophages
    LANCE U'REN
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft Collins, CO 80523, USA
    Cancer Immunol Immunother 59:587-98. 2010
    ..These findings indicate that endogenously produced type I IFNs suppress the generation of TAM, which may in turn account for inhibition of tumor growth and angiogenesis...
  22. pmc Liposome-siRNA-peptide complexes cross the blood-brain barrier and significantly decrease PrP on neuronal cells and PrP in infected cell cultures
    Bruce Pulford
    Department of Microbiology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 5:e11085. 2010
    ..However, delivery of lentivirus encoding PrP shRNA has demonstrated only modest efficacy in vivo...
  23. pmc Protection against pneumonic plague following oral immunization with a non-replicating vaccine
    Abby Jones
    Dept of Microbiology, Immunology, and Pathology, Colorado State University, Ft Collins, CO 80523, USA
    Vaccine 28:5924-9. 2010
    ..Thus, CLDC adjuvanted vaccines represent a new type of orally administered, non-replicating vaccine capable of generating effective protection against pulmonary infection with virulent Y. pestis...
  24. ncbi request reprint Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes
    Karen Zaks
    Department of Microbiology, Immunology, and Pathology, University of Cincinnati College of Medicine and Cincinnati Children s Hospital, OH 45229, USA
    J Immunol 176:7335-45. 2006
    ..tuberculosis. These results suggest that certain TLR agonists can be combined with cationic liposomes to produce uniquely effective vaccine adjuvants capable of eliciting strong T cell responses against protein and peptide Ags...
  25. ncbi request reprint Type I interferons potently suppress gene expression following gene delivery using liposome(-)DNA complexes
    Karen Sellins
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    Mol Ther 12:451-9. 2005
    ..Therefore, type I IFNs appear to play a key role in suppressing transgene expression in vivo following systemic nonviral gene delivery using LDC...
  26. ncbi request reprint Strain-based genetic differences regulate the efficiency of systemic gene delivery as well as expression
    Yong Liu
    California Pacific Medical Research Institute, San Francisco, California 94115, USA
    J Biol Chem 277:4966-72. 2002
    ....