William C Black

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. pmc Gene flow, subspecies composition, and dengue virus-2 susceptibility among Aedes aegypti collections in Senegal
    Massamba Sylla
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 3:e408. 2009
  2. pmc Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti
    Scott A Bernhardt
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 7:e44198. 2012
  3. pmc Dual African origins of global Aedes aegypti s.l. populations revealed by mitochondrial DNA
    Michelle Moore
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 7:e2175. 2013
  4. pmc Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México
    Gustavo Ponce Garcia
    Laboratorio de Entomologia Medica, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, San Nicolas de los Garza, Nuevo Leon, Mexico
    PLoS Negl Trop Dis 3:e531. 2009
  5. pmc A simplified high-throughput method for pyrethroid knock-down resistance (kdr) detection in Anopheles gambiae
    Amy Lynd
    Vector Research Group, Liverpool Tropical School of Medicine, Pembroke Place, Liverpool, UK
    Malar J 4:16. 2005
  6. pmc Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus
    Charles S Wondji
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK
    BMC Genomics 8:34. 2007
  7. ncbi request reprint Flavivirus susceptibility in Aedes aegypti
    William C Black
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    Arch Med Res 33:379-88. 2002
  8. doi request reprint Abundant nuclear copies of mitochondrial origin (NUMTs) in the Aedes aegypti genome
    W C Black Iv
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    Insect Mol Biol 18:705-13. 2009
  9. doi request reprint Why RIDL is not SIT
    William C Black
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA
    Trends Parasitol 27:362-70. 2011
  10. ncbi request reprint Population genomics: genome-wide sampling of insect populations
    W C Black
    Department of Microbiology Colorado State University, Fort Collins, Colorado 80523, USA
    Annu Rev Entomol 46:441-69. 2001

Detail Information

Publications78

  1. pmc Gene flow, subspecies composition, and dengue virus-2 susceptibility among Aedes aegypti collections in Senegal
    Massamba Sylla
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 3:e408. 2009
    ..But few studies have been made of Ae. aegypti s.l. in West Africa. To address this deficiency we have been studying the population genetics, subspecies composition and vector competence for DENV-2 of Ae. aegypti s.l. in Senegal...
  2. pmc Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti
    Scott A Bernhardt
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS ONE 7:e44198. 2012
    ..Furthermore, refractoriness of mosquitoes to infection with dengue virus was significantly positively correlated for nucleotide diversity indices in dicer-2...
  3. pmc Dual African origins of global Aedes aegypti s.l. populations revealed by mitochondrial DNA
    Michelle Moore
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 7:e2175. 2013
    ..Phylogenetic analyses in these many studies consistently resolved two clades but no comprehensive study of mtDNA haplotypes have been made in Africa, the continent in which the species originated...
  4. pmc Recent rapid rise of a permethrin knock down resistance allele in Aedes aegypti in México
    Gustavo Ponce Garcia
    Laboratorio de Entomologia Medica, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, San Nicolas de los Garza, Nuevo Leon, Mexico
    PLoS Negl Trop Dis 3:e531. 2009
    ..Ile1,016 segregates as a recessive allele conferring knockdown resistance to homozygous mosquitoes at 5-10 microg of permethrin in bottle bioassays...
  5. pmc A simplified high-throughput method for pyrethroid knock-down resistance (kdr) detection in Anopheles gambiae
    Amy Lynd
    Vector Research Group, Liverpool Tropical School of Medicine, Pembroke Place, Liverpool, UK
    Malar J 4:16. 2005
    ..Here we present a reliable and potentially high throughput method for screening An. gambiae for the kdr mutation...
  6. pmc Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestus
    Charles S Wondji
    Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK
    BMC Genomics 8:34. 2007
    ..Microsatellite and SNP markers were used to construct a linkage map and to detect a quantitative trait locus (QTL) associated with pyrethroid resistance in the FUMOZ-R strain of An. funestus from Mozambique...
  7. ncbi request reprint Flavivirus susceptibility in Aedes aegypti
    William C Black
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    Arch Med Res 33:379-88. 2002
    ..We end with a discussion of approaches being taken to identify the genes that may control flavivirus susceptibility in Ae. aegypti...
  8. doi request reprint Abundant nuclear copies of mitochondrial origin (NUMTs) in the Aedes aegypti genome
    W C Black Iv
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    Insect Mol Biol 18:705-13. 2009
    ..aegypti NUMTs arise through mtDNA leakage from damaged mitochondria followed by breakage and nonhomologous recombination, rather than through duplicative processes such as transposition or molecular drive...
  9. doi request reprint Why RIDL is not SIT
    William C Black
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA
    Trends Parasitol 27:362-70. 2011
    ..A recent Aedes aegypti case study demonstrates the viability of one of these new transgenic strategies...
  10. ncbi request reprint Population genomics: genome-wide sampling of insect populations
    W C Black
    Department of Microbiology Colorado State University, Fort Collins, Colorado 80523, USA
    Annu Rev Entomol 46:441-69. 2001
    ..The four critical assumptions implicit in the population genomics approach are explained in detail. Studies adopting this paradigm are reviewed, and the steps necessary to complete a population genomics study are outlined...
  11. ncbi request reprint Mitochondrial gene order is not conserved in arthropods: prostriate and metastriate tick mitochondrial genomes
    W C Black
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Mol Biol Evol 15:1772-85. 1998
    ..Correspondence analysis of amino acid and codon use in the two ticks and in nine other arthropod mitochondrial genomes indicate a strong bias in R. sanguineus towards amino acids encoded by AT-rich codons...
  12. ncbi request reprint Affordable assays for genotyping single nucleotide polymorphisms in insects
    W C Black
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    Insect Mol Biol 16:377-87. 2007
    ..We emphasize and explain those techniques in which genotypes can be identified by eye or that only require agarose gel electrophoresis. We provide examples where these techniques have or are currently being applied to insects...
  13. pmc Temporal and geographic evidence for evolution of Sin Nombre virus using molecular analyses of viral RNA from Colorado, New Mexico and Montana
    William C Black
    Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA
    Virol J 6:102. 2009
    ..We investigated the prevalence of intramolecular changes and of genomic reassortment among Sin Nombre viruses detected in deer mice in three western states...
  14. pmc Patterns of variation in the inhibitor of apoptosis 1 gene of Aedes triseriatus, a transovarial vector of La Crosse virus
    Eric T Beck
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Mol Evol 68:403-13. 2009
    ..Initial results indicated that five SNPs were associated with TOT of LACV; however, these results were not replicable with larger sample sizes...
  15. ncbi request reprint Genetic relationships among Aedes aegypti collections in Venezuela as determined by mitochondrial DNA variation and nuclear single nucleotide polymorphisms
    Ludmel Urdaneta-Marquez
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1682, USA
    Am J Trop Med Hyg 78:479-91. 2008
    ..The percentage of mosquitoes exhibiting a midgut infection barrier ranged from 2% to 15%, and those exhibiting a midgut escape barrier ranged from 2% to 18%. Venezuelan Ae. aegypti appear to be susceptible to dengue virus infection...
  16. ncbi request reprint Breeding structure of Aedes aegypti populations in Mexico varies by region
    Norma Gorrochotegui-Escalante
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Am J Trop Med Hyg 66:213-22. 2002
    ..F(ST) values were never large among Pacific collections, suggesting extensive gene flow along the Pacific coast...
  17. ncbi request reprint Variation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United States
    Kristine E Bennett
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Am J Trop Med Hyg 67:85-92. 2002
    ..The MIB and MEB were not completely independent as determined by regression analysis. Midgut infection rates were dose dependent...
  18. pmc Potential for La Crosse virus segment reassortment in nature
    Sara M Reese
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
    Virol J 5:164. 2008
    ..Phylogenetic and linkage disequilibrium analyses revealed that approximately 25% of infected mosquitoes and viruses contained reassorted genome segments, suggesting that LACV segment reassortment is frequent in nature...
  19. pmc The neovolcanic axis is a barrier to gene flow among Aedes aegypti populations in Mexico that differ in vector competence for Dengue 2 virus
    Saul Lozano-Fuentes
    Department of Microbiology, Colorado State University, Fort Collins, Colorado, United States of America
    PLoS Negl Trop Dis 3:e468. 2009
    ..Previous population genetic and vector competence studies have demonstrated substantial genetic structure and major differences in the ability to transmit dengue viruses in Ae. aegypti populations in Mexico...
  20. pmc Identification of super-infected Aedes triseriatus mosquitoes collected as eggs from the field and partial characterization of the infecting La Crosse viruses
    Sara M Reese
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
    Virol J 7:76. 2010
    ..However, previous models predicted transovarial transmission (TOT) to be insufficient to maintain LACV in nature...
  21. ncbi request reprint Dengue virus circulation and evolution in Mexico: a phylogenetic perspective
    Francisco J Diaz
    Arthropod Borne and Infectious Disease Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
    Arch Med Res 37:760-73. 2006
    ..Dengue is the most important arthropod-borne viral infection in the Americas. In the last decades a progressive increment in dengue severity has been observed in Mexico and other countries of the region...
  22. ncbi request reprint Analyses of gene flow among populations of deer mice (Peromyscus maniculatus) at sites near hantavirus pulmonary syndrome case-patient residences
    J Jeffrey Root
    Department of Microbiology AIDL, Colorado State University, Fort Collins, Colorado 80523, USA
    J Wildl Dis 39:287-98. 2003
    ..Overall, these data indicate that SNV trafficking is more likely at the local level, but some long-distance trafficking may be possible, especially where select habitat variables favor long-distance movements...
  23. pmc Alternative splicing generates multiple transcripts of the inhibitor of apoptosis protein 1 in Aedes and Culex spp. mosquitoes
    Eric T Beck
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1692, USA
    Insect Biochem Mol Biol 37:1222-33. 2007
    ..triseriatus and Cx. pipiens was detected by RT-PCR in all mosquito life-stages and adult tissues examined, and the relative concentration of each Ae. triseriatus IAP mRNA variant in various tissues was determined...
  24. ncbi request reprint Genetic variation within the premembrane coding region of dengue viruses from the Yucatan peninsula of Mexico
    Francisco J Diaz
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Am J Trop Med Hyg 67:93-101. 2002
    ..One DEN-2 isolate from 1996 was demonstrated to cluster with viruses of the Sri Lanka genotype, none of which have been detected before in the Americas...
  25. pmc Quantitative trait loci that control dengue-2 virus dissemination in the mosquito Aedes aegypti
    Kristine E Bennett
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, 80523, USA
    Genetics 170:185-94. 2005
    ..The locations of dengue-2 midgut infection and dissemination QTL correspond to those found in earlier studies...
  26. pmc Blood meal identification in off-host cat fleas (Ctenocephalides felis) from a plague-endemic region of Uganda
    Christine B Graham
    Division of Vector Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Am J Trop Med Hyg 88:381-9. 2013
    ..Our findings indicate that cat fleas in human habitations in the West Nile region feed primarily on domesticated species. We conclude that C. felis is unlikely to serve as a Y. pestis bridging vector in this region...
  27. ncbi request reprint An analysis of gene flow among midwestern populations of the mosquito Ochlerotatus triseriatus
    Eric T Beck
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    Am J Trop Med Hyg 73:534-40. 2005
    ..From generation to generation, there is sufficient gene flow to mix families arising from individual breeding sites and eliminate founder effects due to drift...
  28. ncbi request reprint Genetic relatedness of deer mice (Peromyscus maniculatus) infected with Sin Nombre virus
    J Jeffrey Root
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA
    Vector Borne Zoonotic Dis 4:149-57. 2004
    ....
  29. ncbi request reprint Selection of D2S3, an Aedes aegypti (Diptera: Culicidae) strain with high oral susceptibility to Dengue 2 virus and D2MEB, a strain with a midgut barrier to Dengue 2 escape
    Kristine E Bennett
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft Collins, CO 80523, USA
    J Med Entomol 42:110-9. 2005
    ..There were significant differences in MIR and DIR for the different virus strains in both the D2S3 and the D2MEB mosquito lines...
  30. pmc Quantitative trait loci mapping of genome regions controlling permethrin resistance in the mosquito Aedes aegypti
    Karla Saavedra-Rodriguez
    Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523 1685, USA
    Genetics 180:1137-52. 2008
    ....
  31. ncbi request reprint Gene flow pattern among Aedes aegypti populations in Mexico
    Maria De Lourdes Munoz
    Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politiécnico Nacional, Avenida Instituto Politecnico Nacional 2508, Colonia San Pedro Zacatenco, CP 07360, Mexico, DF, Mexico
    J Am Mosq Control Assoc 29:1-18. 2013
    ..Furthermore, based on the distribution of the mosquito haplotypes in America, we suggest that mosquito dispersion is very efficient, most likely due to commercial transportation...
  32. pmc Kinetics of immune responses in deer mice experimentally infected with Sin Nombre virus
    Tony Schountz
    School of Biological Sciences, University of Northern Colorado, Greeley, Colorado, USA
    J Virol 86:10015-27. 2012
    ..Together, these data suggest that a subtle immune response that fails to clear the virus occurs in deer mice...
  33. ncbi request reprint Molecular evidence for trypanosomatids in Culex mosquitoes collected during a West Nile virus survey
    Meg Van Dyken
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    Int J Parasitol 36:1015-23. 2006
    ..We have identified a potential new clade of trypanosomatids that exist within important mosquito vectors and discuss the potential ecological connections between these trypanosomes, arboviruses and mosquitoes...
  34. ncbi request reprint A preliminary linkage map of the tick, Ixodes scapularis
    Amy J Ullmann
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Rampart Road, Foothills Campus, Fort Collins, CO 80522, USA
    Exp Appl Acarol 28:107-26. 2002
    ..8 cM. Assuming a genome size of approximately 10(9) bp, the relationship of physical to genetic distance is approximately 300 kb/cM in the I. scapularis genome...
  35. pmc Rhythms and synchronization patterns in gene expression in the Aedes aegypti mosquito
    Andrey A Ptitsyn
    Center for Bioinformatics, Colorado State University, Fort Collins, CO 80525, USA
    BMC Genomics 12:153. 2011
    ..Circadian gene expression in mosquito species has been previously reported but for only a few genes directly involved in the function of the molecular clock...
  36. ncbi request reprint Mechanisms of insecticide resistance in field populations of Aedes aegypti (L.) from Quintana Roo, Southern Mexico
    Adriana E Flores
    Laboratorio de Entomologia Medica, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Ap Postal 109 F, San Nicolas de los Garza, NL 66450, Mexico
    J Am Mosq Control Assoc 22:672-7. 2006
    ..Slightly elevated levels of MFOs appeared in Lazaro Cardenas females and in Cozumel, Isla Mujeres, and Solidaridad males. Mechanisms involving iAChE or GST were not apparent...
  37. pmc Phylogenetic analysis of West Nile virus, Nuevo Leon State, Mexico
    Bradley J Blitvich
    Colorado State University, Fort Collins, USA
    Emerg Infect Dis 10:1314-7. 2004
    ..Nucleotide sequencing and phylogenetic analysis of the premembrane and envelope genes showed that the virus was most closely related to West Nile virus isolates collected in Texas in 2002...
  38. pmc Transcription of detoxification genes after permethrin selection in the mosquito Aedes aegypti
    K Saavedra-Rodriguez
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1685, USA
    Insect Mol Biol 21:61-77. 2012
    ..Attempts to identify one or a few metabolic genes that are predictably associated with permethrin adaptation may be futile...
  39. ncbi request reprint Aedes aegypti densonucleosis virus amplifies, spreads, and reduces host populations in laboratory cage studies
    Erica L Suchman
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA
    J Med Entomol 46:909-18. 2009
    ..The parameters were used in a Leslie-Lewis matrix model. This model predicted that AeDNV negatively affects Ae. aegypti densities and population structure and thus vectorial capacity...
  40. ncbi request reprint Quantitative trait loci conditioning transovarial transmission of La Crosse virus in the eastern treehole mosquito, Ochlerotatus triseriatus
    Douglas H Graham
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1677, USA
    Insect Mol Biol 12:307-18. 2003
    ..Alleles at the three loci contributed additively towards determining the overall TOT rate and cumulatively accounted for approximately 53% of the phenotypic variance in TOT...
  41. pmc Genetic elimination of dengue vector mosquitoes
    Megan R Wise de Valdez
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    Proc Natl Acad Sci U S A 108:4772-5. 2011
    ..Successful completion of the field trials should facilitate incorporation of this approach into area-wide dengue control or elimination efforts as a component of an integrated vector management strategy...
  42. ncbi request reprint A large scale laboratory cage trial of Aedes densonucleosis virus (AeDNV)
    Megan R Wise de Valdez
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Med Entomol 47:392-9. 2010
    ..aegypti oviposition behavior leads to successful viral dispersal from treated to novel containers in large-scale cages; however, the AeDNV titers reached were not sufficient to reduce egg densities...
  43. ncbi request reprint Heated oligonucleotide ligation assay (HOLA): an affordable single nucleotide polymorphism assay
    W C Black
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    J Med Entomol 43:238-47. 2006
    ..We illustrate the development of HOLA for SNP detection in the Early Trypsin and Abundant Trypsin loci in the mosquito Aedes aegypti (L.) and at the a-glycerophosphate dehydrogenase locus in the mosquito Anopheles gambiae s.s...
  44. doi request reprint High SNP density in the blacklegged tick, Ixodes scapularis, the principal vector of Lyme disease spirochetes
    Janice Van Zee
    Centers for Disease Control and Prevention, Division of Vector Borne Diseases, Fort Collins, CO, USA
    Ticks Tick Borne Dis 4:63-71. 2013
    ....
  45. ncbi request reprint Spatial population genetic structure and limited dispersal in a Rocky Mountain alpine stream insect
    Debra S Finn
    Department of Biology and Graduate Degree Program in Ecology, Colorado State University, Fort Collins, CO 80523, USA
    Mol Ecol 15:3553-66. 2006
    ..IBD was significantly weaker across the entire study area, comprised of three separate islands. Overall, population structure was significant with F(ST) = 0.38, suggesting limited dispersal across a small spatial extent...
  46. ncbi request reprint A mutation in the voltage-gated sodium channel gene associated with pyrethroid resistance in Latin American Aedes aegypti
    K Saavedra-Rodriguez
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA
    Insect Mol Biol 16:785-98. 2007
    ..The tools and information presented provide a means for early detection and characterization of kdr that is critical to the development of strategies for resistance management...
  47. pmc SSCP analysis of cDNA markers provides a dense linkage map of the Aedes aegypti genome
    R E Fulton
    Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Genetics 158:715-26. 2001
    ..Comparative linkage analysis revealed areas of synteny between the two species. SNP polymorphisms are abundant in A. aegypti genes and should prove useful in both population genetics and mapping studies...
  48. pmc A linkage map of the Asian tiger mosquito (Aedes albopictus) based on cDNA markers
    Ian W Sutherland
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Hered 102:102-12. 2011
    ..This was most marked in linkage group I, which varied between 16.7 and 69.3 cM. A map integrating the results from these 4 families with an earlier cDNA linkage map is presented...
  49. ncbi request reprint Resistance to permethrin in Culex tarsalis in northeastern Colorado
    Adam C Strong
    Department of Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, CO 80523, USA
    J Am Mosq Control Assoc 24:281-8. 2008
    ..Both mechanisms may play a role in permethrin resistance or reflect nontarget exposure to other pesticides in Cx. tarsalis in northeastern Colorado...
  50. doi request reprint The Yin and Yang of linkage disequilibrium: mapping of genes and nucleotides conferring insecticide resistance in insect disease vectors
    William C Black
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA
    Adv Exp Med Biol 627:71-83. 2008
    ..We discuss additional approaches that will be needed to identify genes and nucleotides that control phenotypes in field collected organisms, focusing specifically on ongoing studies of genes conferring resistance to insecticides...
  51. pmc Wide spread cross resistance to pyrethroids in Aedes aegypti (Diptera: Culicidae) from Veracruz state Mexico
    Adriana E Flores
    Universidad Autonoma de Nuevo Leon, Facultad de Ciencias Biologicas, Laboratorio de Entomologia Medica, Av Universidad s n San Nicolas de los Garza, Nuevo León 66451, Mexico
    J Econ Entomol 106:959-69. 2013
    ..Bifenthrin appears to be an alternative pyrethroid without strong cross-resistance that could be used as an alternative to the current widespread use of permethrin in Mexico...
  52. ncbi request reprint Genotyping North American animal Mycobacterium bovis isolates using multilocus variable number tandem repeat analysis
    Lorene R Martinez
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
    J Vet Diagn Invest 20:707-15. 2008
    ..bovis animal infections in North America. However, the greatest resolution was achieved by using a combination of both MLVA and spoligotyping...
  53. ncbi request reprint Quantitative trait loci affecting dengue midgut infection barriers in an advanced intercross line of Aedes aegypti
    C Gomez-Machorro
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1677, USA
    Insect Mol Biol 13:637-48. 2004
    ..Alleles at these QTL contributed additively in determining susceptibility and accounted for approximately 24% of the phenotypic variance. Markers associated with a midgut escape barrier were inconsistently supported...
  54. pmc Intensive linkage mapping in a wasp (Bracon hebetor) and a mosquito (Aedes aegypti) with single-strand conformation polymorphism analysis of random amplified polymorphic DNA markers
    M F Antolin
    Department of Biology, Colorado State University, Fort Collins 80523, USA
    Genetics 143:1727-38. 1996
    ..hebetor, while 11% segregated as codominant loci in A. aegypti. SSCP analysis of RAPD-PCR markers offers a rapid and inexpensive means of constructing intensive linkage maps of many species...
  55. pmc Molecular and genetic ecotoxicologic approaches to aquatic environmental bioreporting
    B J Beaty
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    Environ Health Perspect 106:1395-407. 1998
    ..Integrated spatial, structural, and temporal analyses of these parameters will provide invaluable information concerning environmental determinants that restrict or promote gene flow in bioreporter populations...
  56. ncbi request reprint Amplifying whole insect genomes with multiple displacement amplification
    N Gorrochotegui-Escalante
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    Insect Mol Biol 12:195-200. 2003
    ..Genetic polymorphisms revealed at individual loci are the same whether using the original genomic DNA or MDA DNA as a template...
  57. pmc A dengue receptor as possible genetic marker of vector competence in Aedes aegypti
    Ricardo F Mercado-Curiel
    Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Ave Instituto Politécnico Nacional 2508 Col San Pedro Zacatenco, C P 07360, Mexico, DF, Mexico
    BMC Microbiol 8:118. 2008
    ....
  58. ncbi request reprint QCal: a software application for the calculation of dose-response curves in insecticide resistance bioassays
    Saul Lozano-Fuentes
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Am Mosq Control Assoc 28:59-61. 2012
    ..QCal uses a logistic regression model to generate values for lethal dose/knockdown dose based on data from a bioassay entered into the application user interface. The application can be freely distributed to interested parties...
  59. pmc Population-based molecular epidemiology of leprosy in Cebu, Philippines
    Rama Murthy Sakamuri
    Department of Microbiology, Immunology, and Pathology, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523, USA
    J Clin Microbiol 47:2844-54. 2009
    ..These methods provide a molecular database and a rational framework for targeted approaches to search and confirm leprosy transmission in various scenarios...
  60. pmc Comparative genomics of small RNA regulatory pathway components in vector mosquitoes
    Corey L Campbell
    Microbiology, Immunology, and Pathology Department, Colorado State University, Fort Collins, Colorado 80523, USA
    BMC Genomics 9:425. 2008
    ..To do this, we compared the genomic structure of SRRP components across three mosquito species and three major small RNA pathways...
  61. ncbi request reprint Identification of quantitative trait loci affecting sex determination in the Eastern treehole mosquito (Ochlerotatus triseriatus)
    D H Graham
    Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Hered 95:35-45. 2004
    ..The female-biased sex ratio observed in laboratory colonies of O. triseriatus is most easily explained by the existence of multiple female biased distorter loci, as have been observed in other Diptera...
  62. ncbi request reprint Differential lymphocyte and antibody responses in deer mice infected with sin nombre hantavirus or andes hantavirus
    Tony Schountz
    Arthropod Borne and Infectious Diseases Laboratory, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA
    J Virol 88:8319-31. 2014
    ..These data suggest that the rate of maturation of the immune response is substantially higher and of greater magnitude during ANDV infection, and these differences may account for clearance of ANDV and persistence of SNV...
  63. ncbi request reprint Aedes species in treeholes and fruit husks between dry and wet seasons in southeastern Senegal
    Massamba Sylla
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, U S A Departement de Biologie Animale, Faculte des Sciences et Techniques, université Cheikh Anta Diop de Dakar, Dakar, Senegal
    J Vector Ecol 38:237-44. 2013
    ..Aedes aegypti s.l. comprised 55.1% of these, followed by Ae. apicoargenteus (15.2%) and Ae. cozi (11.7%). Similar to East Africa, most (90%) of Ae. aegypti s.l. in the wet season were subspecies formosus. ..
  64. ncbi request reprint Combining real-time polymerase chain reaction using SYBR Green I detection and sequencing to identify vertebrate bloodmeals in fleas
    Christine B Graham
    National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    J Med Entomol 49:1442-52. 2012
    ..Using the established cutoff, our assay detected human, rat, and goat DNA in artificially fed C. felis up to 72 h postfeeding...
  65. ncbi request reprint Infection and pathogenicity of the mosquito densoviruses AeDNV, HeDNV, and APeDNV in Aedes aegypti mosquitoes (Diptera: Culicidae)
    Jeremy P Ledermann
    Arthropod Borne Infectious Disease Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
    J Econ Entomol 97:1828-35. 2004
    ..Accumulation of virus in the larval-rearing water was also observed with values approaching 10-11 logs/ml for each virus. These data indicate that there are dramatic differences in the pathogenicity among mosquito densoviruses...
  66. ncbi request reprint Genome size and organization in the blacklegged tick, Ixodes scapularis and the Southern cattle tick, Boophilus microplus
    A J Ullmann
    Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80522, USA
    Insect Mol Biol 14:217-22. 2005
    ..Genome size and organization in the three tick species so far examined are distinct from other arthropods in having a greater proportion of MR, a lower proportion of unique and HR DNA of very low sequence complexity...
  67. ncbi request reprint Microsatellite loci are not abundant in all arthropod genomes: analyses in the hard tick, Ixodes scapularis and the yellow fever mosquito, Aedes aegypti
    A J Fagerberg
    Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Insect Mol Biol 10:225-36. 2001
    ..These results suggest that microsatellite loci are not universally abundant in arthropod genomes nor do alleles always segregate as codominant markers...
  68. pmc Typing of LaCrosse, snowshoe hare, and Tahyna viruses by analyses of single-strand conformation polymorphisms of the small RNA segments
    W C Black
    Department of Microbiology, Colorado State University, Fort Collins 80523, USA
    J Clin Microbiol 33:3179-82. 1995
    ..The resulting single-strand conformation polymorphism patterns were specific for the respective viruses. This molecular technique offers great potential for virus typing and taxonomic studies...
  69. ncbi request reprint Selection of refractory and permissive strains of Aedes triseriatus (Diptera: Culicidae) for transovarial transmission of La Crosse virus
    D H Graham
    Arthropod Borne and Infectious Diseases Laboratory, Colorado State University, Fort Collins 80523, USA
    J Med Entomol 36:671-8. 1999
    ....
  70. ncbi request reprint Distribution of genetic variation among chromosomal forms of Anopheles gambiae s.s: introgressive hybridization, adaptive inversions, or recent reproductive isolation?
    W C Black
    Department of Microbiology, Colorado State University, Fort Collins, CO 80523 1677, USA
    Insect Mol Biol 10:3-7. 2001
    ..gambiae s.s., increased research on mechanisms of prezygotic reproductive isolation and field-based studies of survival and fecundity in hybrids to test for postzygotic reproductive isolation...
  71. doi request reprint Evidence of multiple chromosomal inversions in Aedes aegypti formosus from Senegal
    S A Bernhardt
    Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA
    Insect Mol Biol 18:557-69. 2009
    ..Recombination rates and gene order were consistent with the presence in Aaf of at least four large inversions on chromosome 1, a single small inversion on chromosome 2 and three inversions on chromosome 3...
  72. ncbi request reprint Developmental- and tissue-specific expression of an inhibitor of apoptosis protein 1 homologue from Aedes triseriatus mosquitoes
    B J Blitvich
    Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Colorado State University, Fort Collins, CO 80523, USA
    Insect Mol Biol 11:431-42. 2002
    ..aegypti, Ae. albopictus and Culex tritaeniorhynchus. Immunoblot analysis revealed that similar amounts of IAP1 were expressed in LaCrosse virus infected and uninfected Ae. albopictus cell cultures...
  73. ncbi request reprint Learning to use Ochlerotatus is just the beginning
    William C Black
    Department of Microbiology, Immunology and Parasitology, Colorado State University, Ft Collins, CO 80523, USA
    J Am Mosq Control Assoc 20:215-6. 2004
  74. ncbi request reprint Gene flow among Anopheles albimanus populations in Central America, South America, and the Caribbean assessed by microsatellites and mitochondrial DNA
    Alvaro Molina-Cruz
    Universidad del Valle de Guatemala, Guatemala City, Guatemala
    Am J Trop Med Hyg 71:350-9. 2004
    ..albimanus populations may have originated from the Caribbean...
  75. ncbi request reprint Large genetic distances among Aedes aegypti populations along the South Pacific coast of Mexico
    Francisco García-Franco
    Department of Genetics and Molecular Biology, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico DF, Mexico
    Am J Trop Med Hyg 66:594-8. 2002
    ..It is likely that dispersal via human commerce in the northeast confounds patterns of natural gene flow...
  76. ncbi request reprint Genomic analysis of detoxification genes in the mosquito Aedes aegypti
    Clare Strode
    Vector Group, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK
    Insect Biochem Mol Biol 38:113-23. 2008
    ..This 'Ae. aegypti Detox Chip' will facilitate the implementation of insecticide resistance management strategies for arboviral control programmes...
  77. pmc Identification and distribution of Mycobacterium leprae genotypes in a region of high leprosy prevalence in China: a 3-year molecular epidemiological study
    Xiaoman Weng
    Beijing Friendship Hospital Affiliate of Capital University of Medical Sciences, Beijing Tropical Medicine Research Institute, 95 Yong An Road, Beijing 100050, People s Republic of China
    J Clin Microbiol 45:1728-34. 2007
    ..Social contact through village markets is proposed as a means of transmission...
  78. ncbi request reprint Phylogeny of parasitiform mites (Acari) based on rRNA
    Hans Klompen
    Department of Entomology, Ohio State University, Columbus, OH 43212, USA
    Mol Phylogenet Evol 43:936-51. 2007
    ..The most species rich mesostigmatid infraorder, Dermanyssina, shows huge distances to the outgroups, but remarkably low within-group divergence in nuclear rRNA. This suggests the possibility of a relatively recent origin of this lineage...

Research Grants7

  1. Genetics of Dengue Vector Competence in Aedes aegypti
    William Black; Fiscal Year: 2001
    ..DS2 and DR2 will be used in the construction of recombinant inbred lines for use in a subtractive hybridization approach to clone cDNAs putatively encoded bydmib3and to assist in a collaborative effort to positionally clone dmib3. ..
  2. Genetics of Dengue Vector Competence in Aedes aegypti
    William Black; Fiscal Year: 2002
    ..DS2 and DR2 will be used in the construction of recombinant inbred lines for use in a subtractive hybridization approach to clone cDNAs putatively encoded bydmib3and to assist in a collaborative effort to positionally clone dmib3. ..
  3. Genetics of Dengue Vector Competence in Aedes aegypti
    William Black; Fiscal Year: 2003
    ..DS2 and DR2 will be used in the construction of recombinant inbred lines for use in a subtractive hybridization approach to clone cDNAs putatively encoded bydmib3and to assist in a collaborative effort to positionally clone dmib3. ..
  4. Genetics of Dengue Vector Competence in Aedes aegypti
    William Black; Fiscal Year: 2004
    ..DS2 and DR2 will be used in the construction of recombinant inbred lines for use in a subtractive hybridization approach to clone cDNAs putatively encoded bydmib3and to assist in a collaborative effort to positionally clone dmib3. ..
  5. Genetics of Dengue Vector Competence in Aedes aegypti
    William Black; Fiscal Year: 2005
    ..DS2 and DR2 will be used in the construction of recombinant inbred lines for use in a subtractive hybridization approach to clone cDNAs putatively encoded bydmib3and to assist in a collaborative effort to positionally clone dmib3. ..
  6. Yellow Fever/Dengue Virus Competence in Aedes aegypt aegypti/formosus in Senegal
    William Black; Fiscal Year: 2009
    ....
  7. Yellow Fever/Dengue Virus Competence in Aedes aegypt aegypti/formosus in Senegal
    William C Black; Fiscal Year: 2010
    ....