Research Topics
| William C BlackSummaryAffiliation: Colorado State University Country: USA Publications
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Publications
The Yin and Yang of linkage disequilibrium: mapping of genes and nucleotides conferring insecticide resistance in insect disease vectorsWilliam C Black
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523, USA
Adv Exp Med Biol 627:71-83. 2008..We discuss additional approaches that will be needed to identify genes and nucleotides that control phenotypes in field collected organisms, focusing specifically on ongoing studies of genes conferring resistance to insecticides...
Genetic relationships among Aedes aegypti collections in Venezuela as determined by mitochondrial DNA variation and nuclear single nucleotide polymorphismsLudmel Urdaneta-Marquez
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1682, USA
Am J Trop Med Hyg 78:479-91. 2008..The percentage of mosquitoes exhibiting a midgut infection barrier ranged from 2% to 15%, and those exhibiting a midgut escape barrier ranged from 2% to 18%. Venezuelan Ae. aegypti appear to be susceptible to dengue virus infection...
Identification of super-infected Aedes triseriatus mosquitoes collected as eggs from the field and partial characterization of the infecting La Crosse virusesSara M Reese
Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
Virol J 7:76. 2010..However, previous models predicted transovarial transmission (TOT) to be insufficient to maintain LACV in nature...- Alternative splicing generates multiple transcripts of the inhibitor of apoptosis protein 1 in Aedes and Culex spp. mosquitoesEric T Beck
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1692, USA
Insect Biochem Mol Biol 37:1222-33. 2007..triseriatus and Cx. pipiens was detected by RT-PCR in all mosquito life-stages and adult tissues examined, and the relative concentration of each Ae. triseriatus IAP mRNA variant in various tissues was determined... - Temporal and geographic evidence for evolution of Sin Nombre virus using molecular analyses of viral RNA from Colorado, New Mexico and MontanaWilliam C Black
Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA
Virol J 6:102. 2009..We investigated the prevalence of intramolecular changes and of genomic reassortment among Sin Nombre viruses detected in deer mice in three western states... - Potential for La Crosse virus segment reassortment in natureSara M Reese
Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
Virol J 5:164. 2008..Phylogenetic and linkage disequilibrium analyses revealed that approximately 25% of infected mosquitoes and viruses contained reassorted genome segments, suggesting that LACV segment reassortment is frequent in nature... - Quantitative trait loci mapping of genome regions controlling permethrin resistance in the mosquito Aedes aegyptiKarla Saavedra-Rodriguez
Department of Microbiology, Colorado State University, Fort Collins, Colorado 80523 1685, USA
Genetics 180:1137-52. 2008.... - Transcription of detoxification genes after permethrin selection in the mosquito Aedes aegyptiK Saavedra-Rodriguez
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1685, USA
Insect Mol Biol 21:61-77. 2012..Attempts to identify one or a few metabolic genes that are predictably associated with permethrin adaptation may be futile... - Aedes aegypti densonucleosis virus amplifies, spreads, and reduces host populations in laboratory cage studiesErica L Suchman
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO, USA
J Med Entomol 46:909-18. 2009..The parameters were used in a Leslie-Lewis matrix model. This model predicted that AeDNV negatively affects Ae. aegypti densities and population structure and thus vectorial capacity... - Selection of D2S3, an Aedes aegypti (Diptera: Culicidae) strain with high oral susceptibility to Dengue 2 virus and D2MEB, a strain with a midgut barrier to Dengue 2 escapeKristine E Bennett
Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft. Collins, CO 80523, USA
J Med Entomol 42:110-9. 2005..There were significant differences in MIR and DIR for the different virus strains in both the D2S3 and the D2MEB mosquito lines... - Dengue virus circulation and evolution in Mexico: a phylogenetic perspectiveFrancisco J Diaz
Arthropod Borne and Infectious Disease Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado 80523 1692, USA
Arch Med Res 37:760-73. 2006..Dengue is the most important arthropod-borne viral infection in the Americas. In the last decades a progressive increment in dengue severity has been observed in Mexico and other countries of the region... - Quantitative trait loci conditioning transovarial transmission of La Crosse virus in the eastern treehole mosquito, Ochlerotatus triseriatusDouglas H Graham
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523 1677, USA
Insect Mol Biol 12:307-18. 2003..Alleles at the three loci contributed additively towards determining the overall TOT rate and cumulatively accounted for approximately 53% of the phenotypic variance in TOT... - Genetic relatedness of deer mice (Peromyscus maniculatus) infected with Sin Nombre virusJ Jeffrey Root
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA
Vector Borne Zoonotic Dis 4:149-57. 2004.... - Gene flow, subspecies composition, and dengue virus-2 susceptibility among Aedes aegypti collections in SenegalMassamba Sylla
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
PLoS Negl Trop Dis 3:e408. 2009..But few studies have been made of Ae. aegypti s.l. in West Africa. To address this deficiency we have been studying the population genetics, subspecies composition and vector competence for DENV-2 of Ae. aegypti s.l. in Senegal... - Rhythms and synchronization patterns in gene expression in the Aedes aegypti mosquitoAndrey A Ptitsyn
Center for Bioinformatics, Colorado State University, Fort Collins, CO 80525, USA
BMC Genomics 12:153. 2011..Circadian gene expression in mosquito species has been previously reported but for only a few genes directly involved in the function of the molecular clock... - Molecular evidence for trypanosomatids in Culex mosquitoes collected during a West Nile virus surveyMeg Van Dyken
Arthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523-1682, USA
Int J Parasitol 36:1015-23. 2006..We have identified a potential new clade of trypanosomatids that exist within important mosquito vectors and discuss the potential ecological connections between these trypanosomes, arboviruses and mosquitoes... - Genetic elimination of dengue vector mosquitoesMegan R Wise de Valdez
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
Proc Natl Acad Sci U S A 108:4772-5. 2011..Successful completion of the field trials should facilitate incorporation of this approach into area-wide dengue control or elimination efforts as a component of an integrated vector management strategy... - Analyses of gene flow among populations of deer mice (Peromyscus maniculatus) at sites near hantavirus pulmonary syndrome case-patient residencesJ Jeffrey Root
Department of Microbiology AIDL, Colorado State University, Fort Collins, Colorado 80523, USA
J Wildl Dis 39:287-98. 2003..Overall, these data indicate that SNV trafficking is more likely at the local level, but some long-distance trafficking may be possible, especially where select habitat variables favor long-distance movements... - Flavivirus susceptibility in Aedes aegyptiWilliam C Black
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
Arch Med Res 33:379-88. 2002..We end with a discussion of approaches being taken to identify the genes that may control flavivirus susceptibility in Ae. aegypti... - Breeding structure of Aedes aegypti populations in Mexico varies by regionNorma Gorrochotegui-Escalante
Department of Microbiology, Colorado State University, Fort Collins 80523, USA
Am J Trop Med Hyg 66:213-22. 2002..F(ST) values were never large among Pacific collections, suggesting extensive gene flow along the Pacific coast... - The neovolcanic axis is a barrier to gene flow among Aedes aegypti populations in Mexico that differ in vector competence for Dengue 2 virusSaul Lozano-Fuentes
Department of Microbiology, Colorado State University, Fort Collins, Colorado, United States of America
PLoS Negl Trop Dis 3:e468. 2009..Previous population genetic and vector competence studies have demonstrated substantial genetic structure and major differences in the ability to transmit dengue viruses in Ae. aegypti populations in Mexico... - Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegyptiScott A Bernhardt
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America
PLoS ONE 7:e44198. 2012..Furthermore, refractoriness of mosquitoes to infection with dengue virus was significantly positively correlated for nucleotide diversity indices in dicer-2... - Why RIDL is not SITWilliam C Black
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, USA
Trends Parasitol 27:362-70. 2011..A recent Aedes aegypti case study demonstrates the viability of one of these new transgenic strategies... - QCal: a software application for the calculation of dose-response curves in insecticide resistance bioassaysSaul Lozano-Fuentes
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA
J Am Mosq Control Assoc 28:59-61. 2012..QCal uses a logistic regression model to generate values for lethal dose/knockdown dose based on data from a bioassay entered into the application user interface. The application can be freely distributed to interested parties... - Population-based molecular epidemiology of leprosy in Cebu, PhilippinesRama Murthy Sakamuri
Department of Microbiology, Immunology, and Pathology, Colorado State University, 1682 Campus Delivery, Fort Collins, CO 80523, USA
J Clin Microbiol 47:2844-54. 2009..These methods provide a molecular database and a rational framework for targeted approaches to search and confirm leprosy transmission in various scenarios... - Genetic variation within the premembrane coding region of dengue viruses from the Yucatan peninsula of MexicoFrancisco J Diaz
Department of Microbiology, Colorado State University, Fort Collins 80523, USA
Am J Trop Med Hyg 67:93-101. 2002..One DEN-2 isolate from 1996 was demonstrated to cluster with viruses of the Sri Lanka genotype, none of which have been detected before in the Americas... - Variation in vector competence for dengue 2 virus among 24 collections of Aedes aegypti from Mexico and the United StatesKristine E Bennett
Department of Microbiology, Colorado State University, Fort Collins 80523, USA
Am J Trop Med Hyg 67:85-92. 2002..The MIB and MEB were not completely independent as determined by regression analysis. Midgut infection rates were dose dependent... - A linkage map of the Asian tiger mosquito (Aedes albopictus) based on cDNA markersIan W Sutherland
Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA
J Hered 102:102-12. 2011..This was most marked in linkage group I, which varied between 16.7 and 69.3 cM. A map integrating the results from these 4 families with an earlier cDNA linkage map is presented... - Infection and pathogenicity of the mosquito densoviruses AeDNV, HeDNV, and APeDNV in Aedes aegypti mosquitoes (Diptera: Culicidae)Jeremy P Ledermann
Arthropod Borne Infectious Disease Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
J Econ Entomol 97:1828-35. 2004..Accumulation of virus in the larval-rearing water was also observed with values approaching 10-11 logs/ml for each virus. These data indicate that there are dramatic differences in the pathogenicity among mosquito densoviruses... - Spatial population genetic structure and limited dispersal in a Rocky Mountain alpine stream insectDebra S Finn
Department of Biology and Graduate Degree Program in Ecology, Colorado State University, Fort Collins, CO 80523, USA
Mol Ecol 15:3553-66. 2006..IBD was significantly weaker across the entire study area, comprised of three separate islands. Overall, population structure was significant with F(ST) = 0.38, suggesting limited dispersal across a small spatial extent... - Resistance to permethrin in Culex tarsalis in northeastern ColoradoAdam C Strong
Department of Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, CO 80523, USA
J Am Mosq Control Assoc 24:281-8. 2008..Both mechanisms may play a role in permethrin resistance or reflect nontarget exposure to other pesticides in Cx. tarsalis in northeastern Colorado... - Quantitative trait loci that control dengue-2 virus dissemination in the mosquito Aedes aegyptiKristine E Bennett
Arthropod-Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, 80523, USA
Genetics 170:185-94. 2005..The locations of dengue-2 midgut infection and dissemination QTL correspond to those found in earlier studies... - Comparative genomics of small RNA regulatory pathway components in vector mosquitoesCorey L Campbell
Microbiology, Immunology, and Pathology Department, Colorado State University, Fort Collins, Colorado 80523, USA
BMC Genomics 9:425. 2008..To do this, we compared the genomic structure of SRRP components across three mosquito species and three major small RNA pathways... - Phylogenetic analysis of West Nile virus, Nuevo Leon State, MexicoBradley J Blitvich
Colorado State University, Fort Collins, USA
Emerg Infect Dis 10:1314-7. 2004..Nucleotide sequencing and phylogenetic analysis of the premembrane and envelope genes showed that the virus was most closely related to West Nile virus isolates collected in Texas in 2002... - Patterns of variation in the inhibitor of apoptosis 1 gene of Aedes triseriatus, a transovarial vector of La Crosse virusEric T Beck
Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
J Mol Evol 68:403-13. 2009..Initial results indicated that five SNPs were associated with TOT of LACV; however, these results were not replicable with larger sample sizes... - A large scale laboratory cage trial of Aedes densonucleosis virus (AeDNV)Megan R Wise de Valdez
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
J Med Entomol 47:392-9. 2010..aegypti oviposition behavior leads to successful viral dispersal from treated to novel containers in large-scale cages; however, the AeDNV titers reached were not sufficient to reduce egg densities... - Genotyping North American animal Mycobacterium bovis isolates using multilocus variable number tandem repeat analysisLorene R Martinez
Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523 1682, USA
J Vet Diagn Invest 20:707-15. 2008..bovis animal infections in North America. However, the greatest resolution was achieved by using a combination of both MLVA and spoligotyping... - An analysis of gene flow among midwestern populations of the mosquito Ochlerotatus triseriatusEric T Beck
Arthropod Borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, CO 80523, USA
Am J Trop Med Hyg 73:534-40. 2005..From generation to generation, there is sufficient gene flow to mix families arising from individual breeding sites and eliminate founder effects due to drift... - A preliminary linkage map of the tick, Ixodes scapularisAmy J Ullmann
Division of Vector Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Rampart Road, Foothills Campus, Fort Collins, CO 80522, USA
Exp Appl Acarol 28:107-26. 2002..8 cM. Assuming a genome size of approximately 10(9) bp, the relationship of physical to genetic distance is approximately 300 kb/cM in the I. scapularis genome... - Learning to use Ochlerotatus is just the beginningWilliam C Black
Department of Microbiology, Immunology and Parasitology, Colorado State University, Ft. Collins, CO 80523, USA
J Am Mosq Control Assoc 20:215-6. 2004 - Mapping a quantitative trait locus (QTL) conferring pyrethroid resistance in the African malaria vector Anopheles funestusCharles S Wondji
Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK
BMC Genomics 8:34. 2007..Microsatellite and SNP markers were used to construct a linkage map and to detect a quantitative trait locus (QTL) associated with pyrethroid resistance in the FUMOZ-R strain of An. funestus from Mozambique... - Mechanisms of insecticide resistance in field populations of Aedes aegypti (L.) from Quintana Roo, Southern MexicoAdriana E Flores
Laboratorio de Entomologia Medica, Facultad de Ciencias Biologicas, Universidad Autonoma de Nuevo Leon, Ap. Postal 109-F, San Nicolas de los Garza, NL 66450, Mexico
J Am Mosq Control Assoc 22:672-7. 2006..Slightly elevated levels of MFOs appeared in Lazaro Cardenas females and in Cozumel, Isla Mujeres, and Solidaridad males. Mechanisms involving iAChE or GST were not apparent... - Large genetic distances among Aedes aegypti populations along the South Pacific coast of MexicoFrancisco García-Franco
Department of Genetics and Molecular Biology, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional, Mexico DF, Mexico
Am J Trop Med Hyg 66:594-8. 2002..It is likely that dispersal via human commerce in the northeast confounds patterns of natural gene flow... - Gene flow among Anopheles albimanus populations in Central America, South America, and the Caribbean assessed by microsatellites and mitochondrial DNAAlvaro Molina-Cruz
Universidad del Valle de Guatemala, Guatemala City, Guatemala
Am J Trop Med Hyg 71:350-9. 2004..albimanus populations may have originated from the Caribbean... - A simplified high-throughput method for pyrethroid knock-down resistance (kdr) detection in Anopheles gambiaeAmy Lynd
Vector Research Group, Liverpool Tropical School of Medicine, Pembroke Place, Liverpool, UK
Malar J 4:16. 2005..Here we present a reliable and potentially high throughput method for screening An. gambiae for the kdr mutation... - Genomic analysis of detoxification genes in the mosquito Aedes aegyptiClare Strode
Vector Group, Liverpool School of Tropical Medicine, Liverpool L3 5QA, UK
Insect Biochem Mol Biol 38:113-23. 2008..This 'Ae. aegypti Detox Chip' will facilitate the implementation of insecticide resistance management strategies for arboviral control programmes... - A dengue receptor as possible genetic marker of vector competence in Aedes aegyptiRicardo F Mercado-Curiel
Department of Genetics and Molecular Biology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Ave Instituto Politécnico Nacional 2508 Col San Pedro Zacatenco, C P 07360, Mexico, DF, Mexico
BMC Microbiol 8:118. 2008.... - Phylogeny of parasitiform mites (Acari) based on rRNAHans Klompen
Department of Entomology, Ohio State University, Columbus, OH 43212, USA
Mol Phylogenet Evol 43:936-51. 2007..The most species rich mesostigmatid infraorder, Dermanyssina, shows huge distances to the outgroups, but remarkably low within-group divergence in nuclear rRNA. This suggests the possibility of a relatively recent origin of this lineage... - Identification and distribution of Mycobacterium leprae genotypes in a region of high leprosy prevalence in China: a 3-year molecular epidemiological studyXiaoman Weng
Beijing Friendship Hospital Affiliate of Capital University of Medical Sciences, Beijing Tropical Medicine Research Institute, 95 Yong An Road, Beijing 100050, People s Republic of China
J Clin Microbiol 45:1728-34. 2007..Social contact through village markets is proposed as a means of transmission...